슬관절에 히야루론산 주입후 발생한 활막성 연골종증 : 증례 보고

최의성,김용민,김동수,손현철,박경진,조병기,배승환 충북대학교 의과대학 충북대학교 의학연구소 2009 忠北醫大學術誌 Vol.18 No.2

활막성 연골종증은 비교적 드문 양성 종양으로 관절내 활액막 결체조직의 양성 반응성 이형성에 의해 여러 개의 연골성 결절을 형성하고 이것이 관절내로 유리되어 유리체를 형성하는 질환으로 주로 슬관절에 발생한다. 활막성 연골종증의 정확한 발생 기전은 아직 밝혀지지 않았으나 외상, 감염 등이 원인으로 제시되고 있다. 저자들은 슬관절 내 히야루론산 주입후 발생한 슬관절내 활막성 연골종증을 1 례 경험하였으며, 관절경적 제거술을 통해 만족스런 결과를 얻었다. As a relatively rare benign tumor, synovial chondromatosis forms several cartilaginous nodules by the benign reactive metaplasia of synovial connective tissues within joints, which are loosed into the joints and cause a disease forming loose body mainly in knee joint. Accurate mechanism of synovial chondromatosis has not been clarified yet; however, trauma, infections and others have been suggested as its possible causes. The authors of this study experienced an example of a patient with synovial chondromatosis in knee joint occurred after the injection of hyaluronic acid in the joints and had a satisfactory outcome through the arthroscopic resection.

하악 제3대구치와 하악관과의 위치관계에 대한 파노라마 방사선사진과 cone beam형 전산화단층영상의 비교

최형수,김규태,최용석,황의환 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.3

Purpose : To assess the diagnostic accuracy and value in an imaging technique field through the comparison of cone beam computed tomography and conventional panoramic radiography in assessing the topographic relationship between the mandibular canal and impacted third molars. Materials and Methods : Participants consisted of 100 patients offered the images through cone beam computed tomography and panoramic radiography. PSR-9000 Dental CT system (Asahi Roentgen Ind. Co., Ltd, Japan) was used as the unit of cone beam computed tomography. CE-II (Asahi Roentgen Ind. Co., Ltd, Japan) and Pro Max (Planmeca Oy, Finland) were used as the unit of panoramic radiography. The images obtained through panoramic radiography were classified into 3 types according to the distance between mandibular canal and root of mandibular third molar. And they were classified into 4 types according to the proximity of radiographic feature. The images obtained through cone beam computed tomography based on the classification above were classified into 4 types according to the location between the mandibular canal and the root and were analyzed. And they were classified into buccal, inferior, lingual, and between roots, according to the location between mandibular canal and root. The data were statistically analyzed and estimated by χ²-test. Results : 1. There was no statistical significance according to 3 types (type l, type ll, type lll) through CBCT. 2. The results of 4 types (type A, type B, type C, type D) through CBCT were as high prevalence of CBCT 1 in type A, CBCT 2 in type B, CBCT 3 in type C, and CBCT1 in type D and those of which showed statistical significance (P value=0.03). 3. The results according to location between mandibular canal and root through CBCT recorded each 49, 25, 17, 9 as buccal, inferior, lingual, between roots. Conclusion : When estimating the mandibular canal and the roots through the panoramic radiography, it could be difficult to drive the views of which this estimation was considerable. Thus it is required to have an accurate diagnostic approaching through CBCT that could estimate the location between mandibular canal and roots.

참당귀(Angelica fifas Nakai)의 캘러스로부터 체세포배 발생에 미치는 계대배양 주기의 영향

최용의,소웅영 全北大學校 基礎科學硏究所 1994 基礎科學 Vol.16 No.-

Embryogenic callus was produced form leaf segments cultured on medium containing 1.0 mg/L 2,4-D. The callus gave rise to somatic embryos after transfer the embryogenic callus to medium without 2,4-D. Also, somatic embryogenesis occured from aged callus on medium containing 2,4-D. To investigate the effects of culture periods on somatic embryogenesis the embryogenic calli were cultured for 2, 4, 6 and 8 weeks on medium containing 1.0 mg/l 2,4-D and then transferred to medium with or without 2,4-D. In prolonged preincubation, somatic embryos were formed early and at high frequency and their development normally occured. When subcultured on medium containing 2,4-D, the callus preincubated for 6 to 8 weeks was capable of producing somatic embryos. Histological observation revealed that 4 weeks-old embryogenic callus on medium containing 2,4-D was composed of mainly typical embryogenic cells, whereas the 8-weeks-old callus was composed of nonembryogeinc cells and that. In the developing state of somatic embryo on medium without 2,4-D, all the cells of callus were in vacuolated and elongated except developing somatic embryos.

rhBMP-2가 저칼슘식이 투여 백서의 골결손부 이유에 미치는 영향

최용석,황의환,이상래 大韓口腔顎顔面 放射線學會 2004 Imaging Science in Dentistry Vol.34 No.1

Purpose : To investigate the effect of rhBMP-2 on the healing of bone defect in the low calcium diet rat. Materials and Methods : To prepare the experimental model, control group was fed a normal diet and experimental group was fed a low calcium diet for 3 weeks. And then, 4 mm bicortical perforated bone defect was made on mandibular body of each rats. Experimental group was subdivided into two groups; experimental group 1 (rats given a low calcium diet before and after bone defect) and experimental group 2 (rats given a low calcium diet before and after bone defect with rhBMP-2 application). At 1, 3, 5 and 7 weeks after bone defect formation, the rats Were terminated. The healing of bone defect was assessed by three-dimensional computerized tomography, soft xray radiography, and histopathological examination. Results : The wound healing of the bone defect for control group, experimental group 1, and experimental group 2 showed a increase from 3 weeks after bone defect formation. The experimental group 2 showed a more increase in healing amount than control group and experimental group 1 from 5 weeks after bone defect formation and the experimental group 2 showed a complete recovery of bone defect at 7 weeks after bone defect formation. Conclusion : The healing process of bone defect is accelerated by rhBMP-2 application in the low calcium diet rats.

Cone beam형 전산화단층영상의 원리

최용석,김규태,황의환 대한구강악안면방사선학회 2006 Imaging Science in Dentistry Vol.36 No.3

The use of computed tomography for dental procedures has increased recently. Cone beam computed tomography (CBCT) systems have been designed for imaging hard tissues of the dentomaxillofacial region. CBCT is capable of providing high resolution in images of high diagnostic quality. This technology allows for 3-dimensional representation of the dentomaxillofacial skeleton with minimal distortion, but at lower equipment cost, simpler image acquisition and lower patient dose. Because this technology produces images with isotropic sub-millimeter spatial resolution, it is ideally suited for dedicated dentomaxillofacial imaging. In this paper, we provide a brief overview of cone beam scanning technology and compare it with the fan beam scanning used in conventional CT and the basic principles of currently available CBCT systems.

만성 요통 환자의 심리사회적 특성

김용민,원중희,최의성,서중배,이호승,허윤무 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.2

연구목적: 만성 요통 환자의 많은 수가 직업 등 주변 환경과 심리 상태의 영향을 받는 것으로 추정되나 그 연관성은 아직 논란이 많다. 본 연구에서는 설문 조사를 통하여 만성 요통 환자의 심리사회적 특성을 알아보고자 하였다. 대상 및 방법. 1997년 7월부터 1998년 12월까지 6주 이상 지속된 만성 요통으로 본원 정형외과 외래를 내원한 환자들 중 기질적 원인이 불명확한 62명의 환자들에서 직업, 유발요인, 치료 등 요통 관련 요소 설문과 Minnesota Multiphasic Personal Inventory (MMPI)를 실시하였다. 요통 관련 사항에는 통증의 기간, 정도, 통증이 유발 또는 심해지는 자세, 그리고 본인이 생각하는 요통의 원인 등을 포함하였다. MMPI는 전체 평균을 이용한 방법과 two-code 방법을 이용하여 평가하였다. 결과: 만성 요통환자의 직업 상 실내에서 앉아 일하는 직업이 가장 맡았으며 일정한 자세를 오래 유지하며 앉거나 서 있는 경우 증상이 악화되는 것으로 기술되었다. MMPI에서는 건강 염려증, 우울증, 히스테리의 세 척도의 평균이 55이상으로 상승되어 있었다. Two-code 방법에서는 92% (46/50)의 환자에서 위 세 척도 중 적어도 하나 이상 상승되어 있었다. 결론: 만성 요통 환자들에서 일상 생활의 자세와 직업이 요통의 발생 및 악화에 영향이 있을 것으로 보여졌다. MMPI를 통한 심리 인성 검사 상 건강 염려증, 우울증, 히스테리의 성향이 증가되어 있어 요통의 발생과 만성화에 심리적 요소가 영향을 미치는 것으로 보여졌다. 사회경제학적, 정신심리학적 요인이 만성 요통에 미치는 영향의 규명을 위한 다양하고 심도 있는 연구가 필요하다고 생각된다. Purpose : Socioeconomic and psychologic factors seem to affect incidence, severity, and chronicity of low back pain. Purpose of this study is to survey socioeconomic factors and document psychoneurotic traits via MMPI in chronic low back pain patients. Materials and Methods : From July 1997 to December 1998, questionnaire about low back pain-related factors such as duration, severity, posture, occupation etc. and MMPI were given to patients who visited our department for chronic low back pain()6weeks). 62 patients completed, and 50 of them completed MMPI. The answers were analyzed. MMPI scores were evaluated in mean±SD method and two-code method. Results : Sedentary workers were the most common. And symptoms were told to be elicited by long sitting or standing posture(job) . Hs, D, Hy scales of MMPI, which are know as "neurotic triad by two-code method was observed in 92% (46/50) . Conclusion : It seemed that job and posture had Important role in chronic low back pain. And, it seemed that chronic low back pain patients had some psychoneurotic traits especially in hypochondriasis, depression, and hysteria. More investigations to document the influences of socioeconomic and psychoneurotic factors in chronic low back pain seems to be necessary.

장기적 흡인 배액법을 이용한 척추 후방 기기 고정술 후 감염의 치료

김용민,김동수,최의성,손현철,박경진,김융성 충북대학교 의과대학 충북대학교 의학연구소 2003 忠北醫大學術誌 Vol.13 No.2

연구 목적 : 척추경 나사못을 이용한 척추 후방 기기 고정술 후 심부 감염이 발생한 증례 들을 대상으로 관련 인자를 분석하고 Hemo-vac을 이용한 장기간의 폐쇄성 흡인 배액법을 통한 치료와 그 결과에 대해 알아보고자 하였다. 대상 및 방법 : 1996년 5월부터 2001년 8월까지 척추후방기기고정술 후 심부 감염이 발생 한 5례를 연구 대상으로 하여 전신 질환 동반, 감염의 발현 양상을 조사하였고, 창상 세척 등 감염 수술 후 장기적 배액법을 이용한 치료 과정 및 최종 결과를 후향적으로 분석하였다. 결 과 : 당뇨와 비만이 술후 심부 감염의 위험요인으로 분석되었다. 수술 환부로부터의 배농, 발열 등 감염 증상은 술후 평균 18.8(8-36)일에 발현되기 시작하였다. 일인당 단 1회의 세척술이 실시되었고 고정기기는 제거하지 않았다. 이후 평균 19.2일간의 지속적 흡인 배농 및 평균 43.6일간의 항생제 정맥투여에 이은 평균 33.8일간의 경구투여로 심부감염은 특별한 합병증 없이 모두 치료되었으며 양호한 임상적 결과와 후외방 골융합을 얻을 수 있었다. 결 론: 척추 후방 기기 고정술 후 발생한 심부 감염에 대해 창상의 세척 및 육아조직 제 거 후 항생제 투여와 Hemo-vac을 이용한 장기간의 장기적 흡인 배액법은 감염의 조절과 척추의 안정성을 동시에 얻을 수 있는 유용한 방법중 하나인 것으로 생각되었다 Purpose: Various treatment modalities have been applied to control deep infection after spinal instrumentation. Validity of removing implants to control the infection is still contro- versial because it may cause loss of spinal stability. Analysis of the inherent risk factors associated with deep infection and the efficacy of management with long-term suction drainage without removal of implants. Materials and Methods : Fiye cases of postoperative deep infection after posterior spinal fixation from May 1996 to August 2001 were investigated on combined general ill- ness, features of infection, various profiles on the management of infection with surgical irrigation and debridement followed by long-term suction drainage, and final outcomes. Results :Remarkable risk factors were diabetes and obesity. Evidences of infection such as discharge from the wound, dehiscence, or fever were observed on the average of 18.8th day postoperatively By only one additional surgical procedure for each patient followed by long-term suction drainage for mean 19.2 days and administration of intravenous antibiotics for average of 43.6 days, deep infections were controlled successfully without removal of implants and without any grave complications. All achieved favorable clinical results and posterolateral fusion. Conclusion : Irrigation and debridement accompanied by long-term suction drainage using Hemo-vac and administration of susceptible antibiotics seemed to be one of the effective methods to control deep infection after posterior spinal instrumentation and main than the postoperative stability of spine.

안전한 CALS/EC 서비스 구현을 위한 정보보호기술 표준화 전략

김의탁,허철호,최용락 大田大學校 産業技術硏究所 1998 산업기술연구소 論文集 Vol.9 No.1

This paper is proposed the standardization strategy of security technology for secure CALS/EC service implementation after analyzing security technology in CALS/EC. In this paper, we discussed about security technology such as cryptography, digital signature, authentication technology and electronic payment protocol(SET) related CALS/EC. In addition to, we investigated why we need the standardization in CALS/EC security technology. According to the standardization, we will expect that compete other developed countries in global market and provide compatibility between heterogeneous systems or countries.

Primary intraosseous carcinoma of the mandible

Hwang, Eui-Hwan,Choi, Yong-Suk,Lee, Sang-Rae 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4

A very uncommon tumor, primary intraosseous carcinoma (PIOC), is a carcinoma arising within the jaw. The definite diagnosis of PIOC is often difficult as the lesion must be distinguished from alveolar carcinoma that may invade the bone from the overlying soft tissues or from the tumors that have metastasized to the jaw from a distant site. A case of PIOC arising in the mandible is presented. The clinical, radiologic, and histologic features are described. This rare lesion should be considered in any differential diagnosis of a jaw radiolucency.

지역의무 공동도급 수주에 의한 공사현장 운영실태 연구

임의수,최응규,조용훈 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

Since the systematic researches on the operation for compulsory local joint contract are not enough, it is required to make efforts the sound activation of this system. This study analyzes and examines the problems occurred at the operation of construction field due to compulsory local joint contract. And tries to suggest effective operational guidelines