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Kim, Sang-Tae,Lee, Seung-Yeon,Kim, Seung-Chul,Byun, Hye-Won,Lee, Sang-Tae,Kim, Mu-Yeal,Hong, Seok-Pyo,Chung, Young-Jae,Park, Ki-Ryong,Lee, Chung-Hee,Lee, Joong-Ku,Heo, Kyeong-In,Lee, Ji-Ye,Lee, Eun-Je National Science Museum of Korea 2011 Journal of Korean nature Vol.4 No.3
We developed the educational purpose mobile application, named "Wild Flowers of Bukhansan National Park (version 1.0)", aiming for easy identification of wild flowers for students and visitors in the park. When visitors find a flower or part of plant in the park, visitors can search for its name utilizing the pictures and characters provided in their own smartphone mobile devices or tablet PCs. The application provides pictures of wild flowers in the park and character-based searching system based on 12 diagnostic features (e.g., growth form, leaf arrangement, flower symmetry, petal color, petal number, sepal number, etc). We adopted the complete floristic survey of Chung and Lee (1962) and added species that we confirmed their distribution in the park during the development of this application. In summary, number of vascular plants in this park was estimated to be 428 taxa including 100 families, 280 genera, 327 species, 1 subspecies, 50 varieties, and 5 formas. We provided a total of 588 pictures representing 358 taxa and each taxon includes multiple pictures in many cases. Included identification quizzes can be an efficient educational tool as well as fun activity for students and visitors who are learning plant species in Korea. Our next step will include GPS function in the application for indicating visitor's location and for providing previously reported sites of the species that we interested in the map of the park. The future application which includes GPS function will be a valuable tool for the monitoring of rare plants, plant researches related to the climate changes, etc. We currently provide Korean iPhone version only, and English version and both of android versions will be serviced soon.
박재현,우보명,김우룡,안현철,조현서,추갑철,김춘식,최형태,Park, Jae-Hyeon,Woo, Bo-Myeong,Kim, Oue-Ryong,Ahn, Hyun-Chul,Cho, Hyun-Seo,Choo, Gab-Chul,Kim, Choon-Sig,Choi, Hyung-Tae 한국환경복원기술학회 2001 한국환경복원기술학회지 Vol.4 No.3
This study was conducted to investigate physicochemical property changes from July 1998 to August 2001 in Mt. Bukhansan National Park. Four water sampling points were selected to measure the quality of stream water in the northeastern part of the Mt. Bukhansan National Park. The results were summarized as follows; In spring, the average pH of stream water was below the first class of the river water quality standard, while it was normal level in summer. The average electrical conductivity was about 2.3~3.3 times higher in downstream water than in upstream water during spring and summer. The contents of anions($Cl^-$, $NO{_3}^-$, $SO{_4}^{2-}$) were about 1.1~7.4 and 0.4~11.4 times higher in downstream than in upstream water, respectively. These results indicate that water quality was poorer in downstream than in upstream water. We suggest that stream water in the Mt. Bukhansan National Park should be protected from impacts of snow melting mineral particles in spring season and human impacts like wastewater of point source in summer season.
The rs196952262 Polymorphism of the AGPAT5 Gene is Associated with Meat Quality in Berkshire Pigs
Woo Bum Park,Sang Mi An,Go Eun Yu,Seulgi Kwon,Jung Hye Hwang,Da Hye Park,Deok Gyeong Kang,Tae Wan Kim. Hwa Chun Park1. Jeongim Ha*.,Chul Wook Kim* 한국축산식품학회 2017 한국축산식품학회지 Vol.37 No.6
High-quality meat is of great economic importance to the pig industry. The 1-acylglycerol-3- phosphate-O-acyltransferase 5 (AGPAT5) enzyme converts lysophosphatidic acid to phosphatidic acid in the mitochondrial membrane. In this study, we found that the porcine AGPAT5 gene was highly expressed in muscle tissue, influencing meat characteristics, and we also identified a non-synonymous single-nucleotide polymorphism (nsSNP) (rs196952262, c.673 A>G) in the gene, associated with a change of isoleucine 225 to valine. The presence of this nsSNP was significantly associated with meat color (lightness), lower cooking loss, and lower carcass temperatures 1, 4, and 12 h after slaughter (items T1, T4, and T12 on the recognized quality scale, respectively), and tended to increase backfat thickness and the waterholding capacity. These results suggest that nsSNP (c.673A>G) of the AGPAT5 gene is a potential genetic marker of high meat quality in pigs.
김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구
이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2
표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.
이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1
연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.
블럭탐색 제어를 이용한 프랙탈 영상 부호화 시간 향상과 컬러 영상에의 응용
박철우,정동웅,김태형,김두영 東亞大學校 附設 情報通信硏究所 1996 情報通信硏究所論文誌 Vol.4 No.1
In this paper, in order to reduce block search area during the process to determine the coefficient of IFS transform equation in Fractal Coding, We performed the following steps : First, We partitioned Domain blocks and Range blocks with certain critical point determined by the edge characteristcs and the direction of brightness. When similar block's detected, the Domain block in the same class of the given range was only searched. Second, When the processing is on, We determined the linear list structure with the second error limit, We, therefore, could control coding time, We tryed to improve the compression rate of the Image with reducing the number of times of tranformation by changing the area of block with Quadtree Partitioning, and also tried to progress the fidelity of the image by changing the search density of search area, according to the magnitude of range block. We applied these method to image compression of 24-bpp color. First of all, after converting the RGB coordinate into YIQ Coordinate which has brightness signal and chrominance signal, We minimized by a quarter and coded I,Q signal which implies the information of the color but takes just small part at image information and on the case of decoding, with linear interpolation method we got I,Q signal enlarged as it was. All throughout these processing, We could find out that There are no damages on the original image, and we are able to make better result on compression rate and fidelity of image comparing with those of conventional Fractal Coding method which was applied to the RGB images.
科學敎師敎育의 實態調査와 그 改善方案 : 物理敎師 敎育을 中心으로
朴泳喆,宋寅命,權寧駿,趙泰環,金英猷 공주대학교 사범대학 과학교육연구소 1986 과학교육연구 Vol.18 No.1
The presnt study is concerned with too purposes. One, immedi-ately, is to use the new physics (science) curriculum revision in the physics (science) teacher preparation institution. The other, ultimately, is to throw some suggestions in curriculum revision and the related agencies and persons. The problems set-up, in detail, are educational objectives, the contents of subject-matter, the methods of instruction, management of curriculum, teacners' problems and opinions to the future education of physics teacher. Not only to analyze the present curriculum but also to develop the new curriculum, three dimensions, theoretical background reflected recent advancement and current topics in science educa-tion, the present status of the secondary school curriculum, the literature survey, and the status quo of college and graduate school curricula preparing qualified science teacher of secondary school are considered in criteria of analysis. The results are the following. The educational objectives set-up are not clear-cur and not appropriate. The contents of subject are not so validated to objectives reflected current science curric-lum of secondary school and philosophy of science teacher educa-tion, and are not made into structure. The methods of assertion and proof and the creative thinking information processing, problem-solving, decision-making are encouraged in the present teaching. In conclusion, the new physics (science) teacher preparation curriculum model appropriate to our situation is presented. The new model emphasized the flexibility of the curriculum managem-ent and stressed the achievement of excellence in teaching of open-competence, the concept of science for all and multi-aspect of modern science and technology.
소음 노출 남성 근로자에서의 청력저하와 혈청 마그네슘의 관련성
박완섭,이종영,정상재,유재영,최태성,홍성철,노성찬 大韓産業醫學會 2000 대한직업환경의학회지 Vol.12 No.1
목적 : 본 연구는 소음에 노출된 남자 근로자를 대상으로 장기간 소음 폭로가 혈청 마그네슘의 농도와 관련이 있는지를 검정하고 이러한 혈청 마그네슘의 농도가 또한 청력저하와 관련이 있는지를 파악하기 위하여 수행되었다. 방법 : 소음에 노출되는 178명의 연구대상자를 청력저하의 정도에 따라 세 그룹으로 분류하고, 구조화된 설문, 신체계측, 혈액검사 등으로 청력저하에 대한 감수성 요인과 혈청 마그네슘 등을 수집하고 측정하였으며, 대상자들의 청력 역치를 측정하기 위하여 청력검사를 실시하였다. 결과 : 본 연구의 결과를 요약하면 다음과 같다. 첫재, 청력저하에 관련된 개인의 감수성 인자라고 알려진 변수인 흡연유무, 나이, 혈압, 헤마토크리트, 콜레스테롤, 혈당 중에서 나이, 이완기 혈압이 단순분석에서 세 그룹간에 차이가 있었고(p〈0.05), 혈청 마그네슘의 농도 또한 세 그룹간에 통계적으로 유의한 차이가 있었으며(p〈0.05) 청력저하가 심할수록 혈청 마그네슘 농도는 낮아지는 경향을 보였다. 둘째, 그룹간의 소음 노출력은 차이가 있었지만 (p〈0.05) 청력보호구 착용상태에는 유의한 차이가 없었다. 셋째, 혈청 마그네슘 농도에 영향을 줄 수 있는 변수인 소음 노출 기간, 마그네슘 함량이 많은 음식의 섭취정도, 스트레스 수준 중에서 소음 노출기간이 혈청 마그네슘 농도와 유의한 상관관계를 보였고(p〈0.05) 노출기간이 길수록 마그네슘의 혈청농도는 낮아지는 경향을 나타내었다. 넷째, 주파수별로 청력저하와 관련된 감수성 요인들에 대한 다중회귀분석 결과 주파수 1,000 Hz에서는 연령이 좌,우측 귀 모두에서 유의한 변수로 채택되었으며 (p〈0.05), 연령이 증가할수록 청력저하가 심해지는 경향을 보였고, 주파수 4,000 Hz에서는 확장기 혈압, 소음 노출 기간, 혈청 마그네슘 등이 청력저하에 대한 감수성 요인으로 채택되었으며(p(0.05), 이완기 혈압이 높을수록, 소음노출 기간이 길수록, 혈청 마그네슘의 농도가 낮을수록 청력저하가 심해지는 것으로 나타났다. Objectivea : This study was conducted to investigate that the chronic noise exposure is associated with decreased serum magnesium concentrations and evaluate whether decreased serum magnesium is associated with noise induced hearing loss. Methods : One hundred seventy-eight male workers exposed to noise were selected and classified three groups by the degree of hearing loss. Hearing threshold levels were less than 30 dB at 1,000 Hz or less than 40 dB at 4,000 Hz In group I, more than 30 dB at 1,000 Hz or more than 40 dB at 4,000 Hz and 15 dB and less of pure tone average[PTA : (500 Hz+l,000 Hz+2,000 Hz)/3] in group II, more than 30 dB at 1,000 Hz or more than 40 dB at 4,000 Hz and over 15 dB of PTA in group III. Results : Serum magnesium concentrations were 2.42±0.26 mg/dl in group 1, 2.35±0.23 mg/dl in group n , 2.26±0.24 mg/dl in group II, respectively and significantly differ-ent between group I and group III (p〈0.01). It was negatively correlated with duration of the noise exposure as correlation coefficient (r) of -0.194 (p(0.05) . Analysis of the multipleregression on hearing threshold levels showed that serum magnesium, diastolic blood pres-sure, duration of the noise exposure were statistically significant at 4,000 Hz (p(0.05) . While only age was statistically significant at 7,000 Hz (p(0.05) . Conclusions : These results suggest that chronic noise exposure may induces decreasein serum magnesium concentrations and that its decreased concentration is related with noise induced hearing loss.