서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

가스크로마토그래피를 이용한 요중 마뇨산 측정시 새로운 시료 전처리 방법의 검증

조수현,임용현,김선민,권호장,하미나,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

Urinary hippuric acid was analyzed by gas chromatography/mass spectrometry method. A simple and economical derivatization procedure using excessive methanol in acidic condition was adopted to esterify hippuric acid. Quantitative analysis was performed with two internal standards, heptadecanoic acid and hydrocinnamic acid, to evaluate the derivatization procedure as an analytical method. Using the standard addition method, linear and reproducible calibration curves were obtained for both internal standards. Calibration experiment showed that good quantitative result could also be obtained with the calibration curve obtained without urine matrix. Recovery rates for the urine samples were in the range of 95.6∼111.4%. Using hydrocinnamic acid as internal standard, analysis time could be reduced.

레미콘 타설 작업 중 발생한 피부 궤양 1례

조수헌,한상환 大韓産業醫學會 1995 대한직업환경의학회지 Vol.7 No.1

The case was described of a 43 year old male who developed burns of the both shins as a result of handling wet cement. After wet cement was spilled into the rubber boots he was wearing, he experienced painful erythema of both lower legs. Several weeks later, medical examination revealed dirty and granulated ulceration of the both shins. The largest ulcer, about 18 by 10 centimeters, was located on the anterior aspect of left lower leg. We concluded that this skin problem resulted from the extreme alkalinity of calcium hydroxide in wet cement, combined with the effects of pressure and occlusion against the skin.

액체막법에 의한 중금속이온의 분리 및 회수

曺文換,丁學鎭,이상인,金振浩,金始中 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

거대고리 리간드는 금속이온과 선택적으로 결합하는데, 이를 이용하여 에멀젼 액체막을 통한 금속이온의 이동에 관하여 연구를 수행하였다. 금속이온은 유기층에 있는 운반체에 의하여 source phase에서 receiving phase으로 이동한다. 운반체로는 거대고리 리간드인 DBN_(3)O_(3)를 사용하였다. 여기에서 에멀젼 액체막을 통한 금속이온의 이동에 관한 요인과 어떤 금속이온의 선택적 분리에 관하여 검토하였다. 금속이온과 거대고리 리간드 그리고 금속이온과 receiving phase내에 있는 음이온에 대한 안정도 상수를 금속이온의 선택적 이동에 대한 척도로 조사하였다. 납이온이 혼합 용액에서 다른 금속이온보다 높은 이동속도를 나타내었다. Receiving phase내의 음이온이 금속이온의 이동에 중요한 역할을 한다. Receiving phase내에 있는 NO_(3)^(-)을 S_(2)O_(3)^(2-) 대치하면 이동량이 증가함을 보였는데 이는 Pb^(2-)-S_(2)O_(3)^(2-) 상호작용이 Pb^(2+)-NO_(3)^(-) 상호작용보다 크기 때문이다. Macrocyclic ligand has been know to selectively bind with metal ions so that ability applied for the transport of metal ions across the emulsion liquid membrane in this study. The metal ions are transproted from the source phase to the receiving phase by the carrier of the organic phase. Several factors involved in the transport of metal ions acrose the emulsion membrane we reported here and these factors proveided the informations for the selective seperation of some metal ion. Stability constants for cation-macrocyclic ligand and metal ion-anion receiving phase interaction are examined as parameters for the prediction of metal ion transport selectivities Pb^(2+) was transported higher rates than the other metal ions in the mixture solution. The interaction of metal ion to anion in receiving phase is important. S_(2)O_(3)^(2-) in replacement of NO_(3)^(-) in the receiving phase enhances the transport of pb^(2-) since Pb^(2-)-S_(2)O_(3)^(2-) interaction is greater than Pb^(2+)-NO_(3)^(+) interaction.

사업장 소음 폭로에 의한 일과성 역치 상승과 회복

조수헌,하미나,한상환,주영수,성주헌,강종원,윤덕로,송동빈,이명학,김선태 大韓産業醫學會 1996 대한직업환경의학회지 Vol.8 No.2

To determine the recovery time from noise-induced temporary threshold shift(TTS), a prospective field study was conducted at three worksites where workers are known to be exposed high level of noise. Subjects were selected according to answers on a questionnaire which inquired about otological history and previous noise exposure, including avocational, military and occupational exposures. After excluding employee with past otologic problems, recent exposure to high level noise, and under medications, total 92 employees participated in the study. Among 92 participants, complete consecutive audiometric examinations were carried out at 0∼2 hours, 5∼7 hours, 14∼16 hours after worktime noise exposure on 26 participants wearing hearing protectors and 22 participants wearing no protective devices. The difference between the hearing level 0∼2 hours after noise exposure and 5∼7 hours is statistically significant by paired t-test(p<0.01). The median recovery times calculated from the data of 22 participants wearing no protective hearing devices are 15.6 hours at 4000Hz, and 7.7 hours, 10.3 hours, 8.4 hours at 1000Hz, 2000Hz and 8000Hz respectively. These data suggest that when measuring the pure tone audiometry for noise exposed workers, at least 16 hours noise-free interval is required.

수산물에 대한 Grapefruit 종자추출물의 항균 및 항산화효과

조성환,서일원,최종덕,주인생 國立統營水産專門大學 附設 水産科學硏究所 1990 수산과학연구소보고 Vol.2 No.-

연속 추출장치를 이용하여 grapefruit 종자를 gl-ycerine으로 추출하고 농축, 조제한 grapefruit 종자추출물(GFSE)의 항균 및, 항산화성 효과를 검토하기 위하여 정어리, 고등어 및 새우와 같은 수산물을 재료로 하여 GFSE를 처리하지 않은 대조구와 GFSE용액 (100, 250, 500, 750, 1,000PPM)으로 처리한 시험구로 나누어 Salmonella tylhi를 접종하여 일정 온도에서 저장하면서 총균수, 과산화물가 및 texture의 변화를 측정하고 GFSE처리후 저장한 수산물을 대조구와 외관, 냄새를 중심으로 관능검사를 실시하였다. 정어리와 고등어의 경우, 최초 균수가 1.9*10^6, 1.8*10^6이었는데 500PPM 농도 첨가하여 5℃에서 50일 저장후 1.1*10^4과 9.0*10^3으로 감소되었고, 새우의 경우 균의 검출이 확인되지 않아 상당히 좋은 항균효과를 나타내었다. 그리고, 3종의 수산물 모두 GFSE처리구가 대조구에 비하여 유의적인 항산화효과가 있음을 나타내었으며, 500~750PPM 농도의 용액을 처리하여 30℃에서 30일간 저장한 수산시료 추출유의 과산화물가는 정어리는 최초 28~45meq/kgdptj 92~143meq/kg(대조구,490meq/kg)로, 고등어는 64~75meq/kg에서 98~137meq/kg(대조구, 406meq/kg)로, 새우는12~20meq/kg에서 21~32meq/kg(대조구, 72meq/kg)로 증가하여 뚜렷한 산패 억제효과를 볼 수 있었다. Texture도 저장기간이 경과함에 따라 감소하는 경향을 나타내었으나 3종 수산물 모두 GFSE용액 처리시험구에서 감소율이 크게 낮아졌다. GFSE를 처리하여 0℃, 0일간 보관한 시험구와 대조구에 관한 관능검사 결과, GFSE를 처리하지 않은 대조구는 열등한 기호도를 보여준 반면, GFSE용액을 500PPM 이상의 농도로 처리한 시험구 모두가 높은 기호도의 관능검사 결관를 나타내었다. The antimicrobial and antioxidant activities of grapefruit seed extract(GFSE), which was extracted with glycerine in the special schematic extraction apparatus, were investigated for handling and processing of fishery products. The effectivity of GFSE has been tried on sardine, mackerel and shrimp divided into six lots for each fishery product: control(no treatment) and five GFSE-treated samples. Samples were inoculated with Salmonella typhi, incubated for 24hrs at 30℃ in dextrose-tryptone broth medium and prepared for microbiological & chemical analysis and organoleptic assessment. The bacteriological analytical results with GFSE(250ppm) showed the reduction of 1.8×10^6→2.0×10^4, 1.9×10^6→1.8×10^4 and 1.6×10^6→2.7×10^3 in total bacterial count for sardine, mackerel and shrimp, respectively. The test results with GFSE(500ppm) showed a 100% reduction of bacterial mackerel treated with GFSE(500ppm) was reduced to 1.1×10^4 and 9.0×10^3 respectively. Antioxidant effect of treatment with GFSE at 500ppm level for three products was significant. LSD test results on organoleptic parameter for the samples treated with various showed a significant influence on the appearance, odor and texture in which at concentration 500ppm level give the excellent scours compared to each control.

비특징 기반의 차량 번호판 인식

조보호,정성환 國立 昌原大學校 精報通信硏究所 1998 精報通信論文集 Vol.2 No.-

In this paper, we propose a nonfeature-based method to recognize vehicle plate characters. Previous feature-based requires complex preprocessing on a vehicle plate area. The problems of these approaches are the plate binarization process which causes distorted characters and difficult feature vector extraction. In the proposed method, we simplify the previous complex preprocessing. We also use the location information of characters in the vehicle plate area and the color intensity difference between the character region and the background region in the vehicle plate area. Our method then directly recognizes the extracted character region by using ART2 neural network. We perform experiments with extracted 77 vehicle image under various lighting condition. In the experimental results, our proposed method is not sensitive to the lighting condition. It also shows about 92%, 0.1 sec in terms of the total recognition rate and the recognizing time, respectively.

인삼 및 인삼밭 토양의 무기성분 정량에 관한 연구

趙漢玉,李重和,趙成桓 세종대학교 1978 세종대학 논문집 Vol.7 No.-

The author investigated the physical and chemical properties of the soil which ginsengs were cultivated and minerals in Korean ginseng were analyzed. The results were summarized as follows: 1. The soil which ginsengs were cultivated was that of Lithosel or reddish yellow Podzolic. 2. Ginseng tail showed the higher values in the contents of all the minerals than white ginseng. Other minerals except Na, Cu, and P seemed to be more abundant in the ground part than in ginseng root and in ginseng leaves, especially, such elements as Fe, Cu, Zn, and Mn were distributed in great quantities. 3. The content of Ca in ginseng root increased gradually according to growth stage and that of K, Na and Mg decreased on the contrary. 4. In the course of manufacturing of red ginseng, some minerals and proximate components were washed away. 5. Ginseng tails were extracted with ethyl alcohol and concentrated. The extraction yields of chemical components in ginseng extract were as follows: fat: 52.4% free sugar: 87.4% the other proximate component: 15-30% K: 68.1% Na: 54.6% P_2O_5:48.2% Mg: 41.2%

執行任員의 法的地位와 責任

조성환 동국대학교 대학원 1999 大學院硏究論集-東國大學校 大學院 Vol.29 No.-

Company is run by the following two factors: the board of directors, which is composed with all directors or executive members, makes decision making on the management. Then directors and other members carry out those decisions in accordance with the board of director's decisions. The board of directors has many problems for its efficiency and so on. The executive officer which is defined as "a person, selected and appointed by the board of directors and is in charge of partial management under the leadership of director" has been emerged as the potential solution to the decision-making, and the management function after the functional division of the supervision and the managerial. This system has been established early in the U.S.A. so that the officer, independent from executive, has the authority and duty of care comparable to those of the executives. In Japan, since Sony Company adopted this system and reduced the member of directors in 1998 other companies has considered this positively and affirmatively. As of now Korea has discussed on this insufficiently. But to raise the level of transparency of company and to step up the investment of foreign institutional investors further, in the respect of the accordance of corporate governance to global standards. This system is left much to be discussed. In this regard I have analyzed the possible ensuring problems after the adoption of this system into our country in comparison with the cases in U.S.A. and Japan. In the first chapter, I have examined the background of the recent polemic concerning the executive officer and defined the term executive officer, and in the second chapter the background and the reason of adoption of the executive officer. In the third and fourth chapters, I have included its developments in U.S.A and in Japan, respectively, and in the fifth chapter, I have examined the possible problems after the adoption of this system into our country. Finally in the sixth chapter, I have summarized the results of this study.

위암의 Epidermal Growth Factor 및 Epidermal Growth Factor Receptor 표현에 관한 연구

조백환,정상우,조규혁 대한의학협회 1990 대한의학협회지 Vol.33 No.8