한국여성의 연령별 골밀도 : 대구지역을 중심으로

이희자,최미자,이인규 대한골대사학회 1996 대한골대사학회지 Vol.3 No.1

익산시와 서울시 여고생의 식습관 및 영양 섭취 상태에 관한 연구

김인숙,이윤희,김희주 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.2

This study was carried out to investigate the dietary behaviors and nutrient intake of high school girls in Iksan and Seoul cities. The subjects consisted of 122 students in Iksan city, and 136 students in Seoul city. The proportion of subjects who eat meals irregularly was higher in Iksan (98.4%) than in Seoul (80.9%). The proportion of subjects who skip meals was also higher in Iksan (61.5%) than in Seoul (56.6%), and most of them (69.7%) skipped breakfast, even though they thought that it was the most important meal (86.4%). The subjects vended to overeat at lunch (41.9%) and dinner (55.4%). The main reasons that the subjects skipped a meal were a lack of time (50.7%) and poor appetites (23.7%).Most of the subjects (57.4%) had tried to control their body weight by taking drugs (40.5%), doing exercise (34.5%), and controlling their diet (25%). The average intake of nutrients and energy was significantly higher (P<0.05, P<0.01) in Iksan than in Seoul. The intake was below the RDA recommendations except for phosphorus in Iksan, but was above it except for calcium, iron, and vitamin B2,in Seoul. The indexes of nutritional quality (INQ) of calcium (0.5), iron (0.6), vitamin A (0.8), vitamin B2 (0.7), niacin (0.9), and vitamin C (0.9) were under 1.0 but those of protein (1.0), phosphorus (1.2) and thiamin (1.0) were over 1,0. The INQ of the other nutrients, except protein and vitamin C,was significantly higher in Seoul than in Iksan.

DYNAMIC RESPONSE OF CARBON NANOTUBES DISPERSED IN NEMATIC LIQUID CRYSTAL

YOUNG HEE LEE,SANG YOUN JEON,KYUNG AH PARK,IN-SU BAIK,SEOK JIN JEONG,SEOK HO JEONG,안계혁,SEUNG HEE LEE 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2007 NANO Vol.2 No.1

The alignment and dynamic response of carbon nanotubes (CNTs) in nematic liquid crystal (NLC) medium induced by strong electric field have been observed through polarizing optical microscope. Density-functional calculations suggest that LC molecule anchors helically to the CNT wall to enhance π-stacking with a binding energy of nearly -2.0 eV due to a considerable amount of charge transfer from LC molecule to CNT, resulting in the formation of excess charges and permanent dipole moment in CNTs. Under strong electric field, the motion of CNTs distorted the director of adjacent LC molecules. Our detailed analysis of dynamics revealed that the four-lobe textures in vertical cell and two vertical stripes in in-plane switching cell were strongly correlated, i.e., the side view of textures by the vertical motion of CNTs in vertical cell was similar to the textures in in-plane switching cell. Interestingly, the magnitude of textures in microscope was strongly dependent on the size of CNTs and theapplied field strength. The statistical size distribution of textures similar to that of CNTs provided information for the degree of dispersion of CNTs.

Probing the Issue of Informed Consent in Health Care in Korea―Concept Analysis and Guideline Development

Won-Hee Lee,In-Sook Kim,Byung-Hye Kong,Sue Kim,Sunhee Lee 한국간호과학회 2008 Asian Nursing Research Vol.2 No.2

Purpose The purpose of the study was to identify how informed consent is conceptualized by patients, family members, physicians, and nurses in Korea, and to develop guidelines for clinical practice in Korea. Methods This study employed the hybrid model to define the concept of informed consent through theoretical and fieldwork phases. For the theoretical phase, attributes of informed consent were identified through a review of the literature, and in-depth interviews were conducted for the fieldwork phase to develop attributes from the data and to verify the attributes identified from the literature review. Purposive sampling was done for 48 participants (12 patients, 12 family members, 12 physicians, 12 nurses), who were interviewed from selected units (orthopedics, cardiothoracic surgery, obstetrics/gynecology) from two university hospitals in Seoul and Kwangju, Korea. Attributes and processing issues of informed consent were extracted from both phases. Results Core attributes of informed consent include the patient’s self-directed decision-making, fulfillment of legal responsibility, focusing on forging a trusting relationship, assuming active responsibility for explanations (physicians) and granting consent (patient), factors related to sufficient explanation, and the role of family. Findings were integrated into a set of guidelines for patients and family and health care professionals. Conclusion The guidelines developed in the present study offer empirical parameters for an effective process of obtaining informed consent in Korea by seeking to decrease the gap in perceptions of informed consent among patients, family members, physicians, and nurses. The importance of advocating patients and developing a trusting relationship between health care providers and patients is especially noteworthy. [Asian Nursing Research 2008;2(2):102–112] Purpose The purpose of the study was to identify how informed consent is conceptualized by patients, family members, physicians, and nurses in Korea, and to develop guidelines for clinical practice in Korea. Methods This study employed the hybrid model to define the concept of informed consent through theoretical and fieldwork phases. For the theoretical phase, attributes of informed consent were identified through a review of the literature, and in-depth interviews were conducted for the fieldwork phase to develop attributes from the data and to verify the attributes identified from the literature review. Purposive sampling was done for 48 participants (12 patients, 12 family members, 12 physicians, 12 nurses), who were interviewed from selected units (orthopedics, cardiothoracic surgery, obstetrics/gynecology) from two university hospitals in Seoul and Kwangju, Korea. Attributes and processing issues of informed consent were extracted from both phases. Results Core attributes of informed consent include the patient’s self-directed decision-making, fulfillment of legal responsibility, focusing on forging a trusting relationship, assuming active responsibility for explanations (physicians) and granting consent (patient), factors related to sufficient explanation, and the role of family. Findings were integrated into a set of guidelines for patients and family and health care professionals. Conclusion The guidelines developed in the present study offer empirical parameters for an effective process of obtaining informed consent in Korea by seeking to decrease the gap in perceptions of informed consent among patients, family members, physicians, and nurses. The importance of advocating patients and developing a trusting relationship between health care providers and patients is especially noteworthy. [Asian Nursing Research 2008;2(2):102–112]

관상동맥 스텐트 시술 후의 재협착에 관한 연구

김윤철,이정우,김보영,강정아,임대승,이민수,김정희,성보영,최성준,성인환,전은석 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.1

Coronary stent implacement is known as an effective treatment in the intimal dissection after percutaneous transluminal coronary angioplasty and the prevention of restenosis. However, In-stent restenosis still remains a major concern in clinical stenting. The stents were placed in 103 patients from July 1996 to March 1999 and performed follow-up coronary angiograms in 59(57.3%) patients. To identify the clinical, angiographic and procedurerelated variables 'which predict late restenosis within the stented artery, 59 patients(58.3±9.9, M:F= 41:18) were studied. The clinical characteristics of the patients were stable angina in 23(39.0%), unstable angina in 14(23.7%), acute myocardial infarction in 21(35.6%) and old myocardial infarction in 1(1.7%). Coronary stenting was performed in 1 patient(1.7%) for primary lesion, 50 patients(84.7%) for suboptimal results after PTCA, 6 patients(10.2%) for bail-out procedure, and 2 patients(3.4%) for restenotic lesions. All patients were treated with aspirin and ticlopidinc. The follow-up angiograms were obtained at 7±4 months. The overall in-stent restenosis rate was 27.1%. The coronary angiographic findings were 32 single vessel(54.2%), 19 two vessel(32.2%) and 8 three vessel disease(13.6%). The angiographic morphological characteristics were type A in 33(55.9%), type B in 14(23.7%), type C in 12(20. 3%) cases. Variables of 16 patients with restenosis were compared with those of 43 patients without restenosis. Previously known predictors for in-stent restenosis were multiple stenting, stenting for restenotic lesions, residual stenosis after stenting, stenting for total occlusion lesions, reference diameter, balloon to vessel ratio, acute gain and minimal luminal diameter after procedure, design and characteristics of stents, ostial lesion of aorta, high pressure method for stenting, lesion length, diabetes mellitus, size of artheroma, saphenous vein grafts, ulcerlating lesions and calcified lesions. In this study, Reference diameter before stenting(2.43±0.54mm vs. 2.88±0.65mm, p=0.016) and balloon-to-artery ratio(1.28±0.26 vs. 1.11±0.18, p=0.006) were predictors for in-stent restenosis. 1) The overall in-stent restenosis rate was 27.1%. 2) In the analysis of predictors for in-stent restenosis, there was no significant differences in clinical, angiographic factors between group with restenosis and without restenosis. But, Only reference diameter before stenting and balloon-toartery ratio were predictors of late in-stent restenosis. In conclusion, stenting is effective revascularisation method for selected patients with ischemic heart disease, and to minimize in-stent restenosis rate, stent implanting is achieved in a large vessel on the basis of an artery-to-stnet ration of 1:1, if possible.

Uncoupling Protein 3의 골격근 세포내 과발현이 OLETF 백서 및 배양된 골격근 세포에서 포도당대사에 미치는 영향

한정희,박혜선,고정민,김하영,강호경,이인규,박중열,홍성관,이재담,이기업 대한당뇨병학회 2002 Diabetes and Metabolism Journal Vol.25 No.6

연구배경:Uncoupling protein(UCP)는 미토콘드리아의 내막에 위치하는 단백질로 세포내의 과다한 에너지를 열로 발산시키는 기능을 가진다. 최근 동물의 갈색지방조직에만 존재하는 UCP와 유사성을 가진 아형들(UCP2,3)이 사람에게도 존재함이 알려져 큰 관심을 끌도 있는데 이중 UCP3는 그 발현이 골격근세포와 갈색지방조직에만 국한된다. 본 연구에서는 UCP3가 체내 인슐린 감수성을 결정하는데 가장 중요한 조직인 골격근에 국한되어 발현되는 점에 착안하여 UCP3를 골격근세포에 과발현시켰을 때 포도당 대사에 어떠한 영향이 나타나는 지를 조사하였다. 방법:25주령의 8마리의 OLETF 백서를 대상으로 하여 4마리는 골격근에 adenovirus 2mL(1×10¹²pfu/mL)를 주사하여 대조군으로 하였고 4마리는 골격근에 재조합법으로 제작된 adenovirus­UCP3 2mL(1×10¹²pfu/mL)를 주사하였다(UCP3 과발현군). UCP3를 투여한 백서에서 먹이섭취가 증가하는 경향이 있어 그 전날 대조군이 먹은 야의 먹이만큼 투여하였다. 골격근에 adenovirus를 주사한 10일 후에 euglycemic hyperinsulinemic clamp를 시행하였다. Adenovirus­UCP를 C2C12 골격근 세포에 transfection시켜 UCP3를 C2C12 골격근 세포에 transfection시켜 UPS3­C2C12를 만들고 C2C12 골격근 세포와 UPS3­C2C12 골격근 세포에서 포도당 수송 및 당원합성을 측정하였다. 결과:UCP3 과발현 OLETF에서 체중이 감소하는 경향을 보였고 인슐린 감수성이 증가하였다. C2C12세포에서 기저상태 포도당 수송은 1.28±0.17μmol/L/min였고 100nM 인슐린으로 2시간 처리한 후 2.67±0.20 μmol/L/min로 증가하였다. UCP3­C2C12 세포에서는 기저상태 포도당 수송이 3.98±0.13μmol/L/min로 증가되었고 인슐린 처리 후 5.74±0.44μmol/L/min로 증가하였다. 인슐린을 처리한 UCP3­C2C12 세포에 P13K 억제제인 wortmannin을 첨가하였을 때 포도당 수송활성이 3.81±0.20μmol/L/min로 감소하였다. 기저상태 당원합성은 C2C12 세포에서 0.25±0.01μmol/L/min였고 인슐린 처리 후 0.45±0.01μmol/L/min로 증가하였다. UCP3­C2C12 세포에서는 기저상태 당원합성이 0.62±0.01μmol/L/min였고 인슐린 처리 후 1.26±454μmol/L/min로 증가하였다. UCP3­C2C12세포에 wortmannin을 첨가하였을 때 당원합성율이 0.80±0.04μmol/L/min로 감소하였다. 결론:UCP3 과발현이 OLETF 백서에서 인슐린 감수성을 증가시켰고 골격근세포에서 포도당 수송 및 당원합성을 증가시켰다. wortmannin을 첨가하였을 때 포도당 수송 및 당원합성이 감소함으로 보아 이 과정이 인슐린 신호전달체계인 P13K에 일부 의존함을 알 수 있었다. Background : UC P3 is a mitochondrial membrane protein expressed selectively in the skeletal muscle and brown adipose tissue. Since the skeletal muscle is the main organ determining insulin sensitivity in the body, it was hypothesized that UCP3 overexpression in skeletal muscle cells would improve glucose metabolism. Methods : An adenovirus-UCP3 was produced by a recombinant DNA method. OLETF rats were divided into 2 groups. Four rats were injected with the adenovirus-UCP3 (UCP3 group) and others were injected with the adenovirus(control group) in the skeletal muscle. The UCP3 group was provided with the same quantity of food as that consumed by the control group on the previous day. Insulin sensitivity was evaluated by the euglycemic hyperinsulinemic clamp method. In a separate experiment, glucose transport and glycogen synthesis we evaluated in C2C212 cells transfected with ether an adenovirus or the adenovirus-UCP3. Results : The insulin sensitivity improved significantly and the body weight decreased in the UCP3 group. The glucose transport and glycogen synthesis were higher in the UCP3-C2C12 skeletal muscle cells at the basal state. After insulin treatment, glucose transport and glycogen synthesis were also higher in the UCP3-C2C12 cells but the increments were reduced after treatment with wortmannin, a PI3K inhibitor. Conclusion : Insulin sensitivity was higher in the UCP3-overexpressed OLETF rats in the in vivo study. UCP3 transfection also increased glucose transport and glycogen synthesis in the cultured skeletal muscle cells by a PI3K dependent mechanism(J Kor Diabetes Asso 25 :460~468, 2001).

HPLC를 이용한 지역 농산물의 비타민 B₆ 함량 분석

최소라 ( So-ra Choi ),송은주 ( Eun-ju Song ),송영은 ( Young-eun Song ),최민경 ( Min-kyung Choi ),한현아 ( Hyun-ah Han ),이인석 ( In-sok Lee ),신소희 ( So-hee Shin ),이기권 ( Ki-kwon Lee ),최용민 ( Young-min Choi ),김행란 ( Haeng-r 한국식품영양학회 2017 韓國食品營養學會誌 Vol.30 No.4

Contents of water soluble vitamin B6 in a total of 62 agricultural products cultivated in local areas in Korea were analyzed by high performance liquid chromatography with fluorescence detector (HPLC/FLD). To verify the method of vitamin B6 analysis, a quality control chart was formulated with in-house control using a mixture of broccoli and shiitake mushrooms. Among cereals, high content of vitamin B6 measured 234.3~260.3 μg/100 g in dried mung bean and soybean. Vitamin B6 content of non-glutinous and glutinous black rice measured 105.0 μg/100 g and 129.7 μg/100 g, respectively. In vegetables, high content of vitamin B6 were measured in passion fruit (104.3 μg/100 g), gat (55.7~84.3 μg/100 g), gomchwi (31.3~88.0 μg/100 g) and garlic (72.7~98.3 μg/100 g). Among fruits, gold kiwi 'Zespri' and green kiwi 'Hayward' revealed high vitamin B6 content of 116.3 μg/100 g and 78.7 μg/100 g, respectively. In persimmons, daebongsi had high vitamin B6 content (36.0~72.7 μg/100 g) than bansi and sweet persimmon. Vitamin B₆ content in dried jujube and persimmon increased more than 86.7 μg/100 g compared to fresh materials. Among specialty crops, green tea powder (64.7~251.0 μg/100 g) and sansuyu (172.3 μg/100 g) revealed high content. Of mushrooms, vitamin B6 content of Sparassis crispa (139.3 μg/100 g) was the highest. Vitamin B6 content information of agricultural products in local areas in Korea collected from this experiment will be used as valuable preliminary data for grasp national nutritional status.

또래집단의 사회적 강화가 아동의 구강보건행태에 미치는 효과

이난희,박인혜 韓國學校保健學會 2000 韓國學校保健學會誌 Vol.13 No.1

The relationships between children's health behavior and variables that effect children's health behavior has been investigated in a number of previous studies. This study was conducted to examine the effects of a peer's social reirforcement on children's dental health behavior in an elementary school. The research design was a nonequivalent pre and post-test quasi-experimental design and the study subjects with one hundred and thirteen eight to nine years old children, and their mothers(57 experimental group, 56 control group) were selected as a study group. Subjects were selected by the convenience sampling method. The study was carried out in an elementary school in Namwon city, Korea, from the 26th of Apil to the 12th of June in 1999. Data were collected in both the pre and post-test portions. Using the $quot;Health Belief Model$quot;, each item of the questionnaire for measurement of dental health behavior was nudified and administered for the children and their mothers. The questionnaire for the measurement of dental health behavior was developed by Oh, Y.B.(1994). The Cronbach's o of the questionnaire for children were .81, and for the mother were 79. In this study, the health belief mudel consists of $quot;perceived susceptibility$quot;, $quot;perceived seriousness$quot;, $quot;perceived barrier$quot;, $quot;perceived salience$quot;, and $quot;perceived benefit$quot;. The questionnaire for the children was composed of 37 items, and the questionnaire for the muther was composed of 40 items. Data were analyzed by frequency, x²-test ANOV4 Pearson's Correlation, and multiple regression analysis by a SAS program. The results of this study were summarized as follows ; 1. The first hypothesis that the experimental group would have more change in the frequency of brushing per week than that of control group was accepted(t=3.817, p=0.000). Mean tooth brushing score sin the experimental group impoved signif4cantly from pre-test to post-test, but in the control group there was no significant impovement in tooth brushing scores. 2. The second hypothesis that the experimental grnup would have more change in score of dental health behavior than that of control group was accepted (benefit . 1=2.804, p=0.006, salience : t=2.608, p=0.010). An evaluation between the experimental group and the control group showed significant change from Pre-test to post-test in health behavior scores. 3. The third hypothesis that higher scores of social reidorcement would crcate mure change in the scores of tooth brushing frequency in the experimental group was accepted (β =0.169, p=0.000). Multiple regression was used to examine the peer's social reinforcement scores and the relative Hluence of significant variables in fevious ANOVA and Pearson's correlation test on children's frequency of brushing during the Post-test. The results of the study indicated that the combination of social reinforcement of peers with variable spertaining to mother and householder were signif4cantly related and effectively improved a child's tooth brushing.

한국여성의 연령별 골밀도와 생화학적 지표와의 관계 : 대구지역을 중심으로

이희자,이인규 대한골대사학회 1996 대한골대사학회지 Vol.3 No.1

現代社會에서의 老人의 居住意識에 관한 硏究

李仁喜 同德女子大學校 1985 同大論叢 Vol.15 No.1

This study was performed to suggest a basic information on the living environment and elders welfare which are suitablie to the elders from their consciousness of habitation in the modern society in which the number of elders is gradually increased. The samples of this study were randomly selected 60 males and 58 females over sixty-year-old from apartments of Walker Hill, Jamsil Chokong and Daerim and Sajik place of pastime for the elders in Seoul. The method of ivestigation was based on the survey with questionares which were asking the preference of live together with sons and daughters or live alone, in the case of live together, with whom did they wish to live together, and as the factors of the preference, sex, age, education and the living status were analyzed. Statistical data analysis was made to obtain frequency, percentages, χ², degree of freedom and P by computer. The results obtained were summarized as follows. 1. Preference for habitation: It was shown that 71.7% of male and 63.5% of female elders prefer to live together with their son and daughter more females wish to live alone compared to males. As the factors of preference, the living status and the number of children were statistically significant but sex, age, education and condition of health were not found significant. 2. The children with whom the elders wish to live together: It was exhibited that 70.6% of samples wish to live together with the eldest son and daughter-in-law and 18.8% of samples wish to live together with the second son and daughter-in-law and only 5.9% of samples wish to live together with a daughter and son-in-law. As the factors of preference, age, education, living status and health condition showed a significance but sex and the number of children did not show any significance. 3. Reasons for live together with children: Economically profitable shpwed a significance in case the living status was low. Trustworth whowed a significance in case the living status was low and in female. The sweet performance of the great children did not show any significance. It is feel easy because of children's support showed a significance only in the case of low living status. It is comfortable bacause of sharing house affairs showed a significance only in the case of sex and living status. Traditional habit showed a significance only in the case of female and living status. 4. reasons for the preference of living alone: It is inconvenient because of the generation gap showed a significance in sex. It is uneasy because to pay attention showed a significance only in the high living status by living together and no significance was observed in other cases.