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각종 치과레이저의 Streptococcus mutans에 대한 증식 기능억제 효과
한강석,국중기,유소영,김화숙,박종휘,박현동,이상훈 大韓小兒齒科學會 2003 大韓小兒齒科學會誌 Vol.30 No.3
레이저의 구강내 산 생성 세균인 S. mutans에 대한 증식 및 기능 억제효과를 평가하기 위하여 S. mutans KCTC 3065가 포함된 세균 pellet에 Er:YAG 레이저와 Nd:YAG 레이저를 비접촉식 방법으로, 조사세기 50mJ, 조사시간 5초, 그리고 pulse repetition rate를 각각 10Hz와 30Hz로 하여 조사하고 세균 군락수, 산 생성능, 불용성 세포외다당류의 합성량을 측정하여 다음과 같은 결과를 얻었다. 1. Chinese ink로 photosensitization을 시행한 후 Nd:YAG 레이저를 조사한 경우가 S. mutans의 증식을 가장 많이 억제하였으며 Er:YAG 레이저 조사도 증식을 억제하였다. Chinese ink를 사용하지 않고 ND:YAG 레이저를 단독으로 조사한 경우는 S. mutans의 증식을 억제하지 못하였다. 2. Chinese ink로 photosensitization을 시행한 후 Nd:YAG 레이저를 조사한 경우가 일정기간 동안 S. mutans의 산생성능을 가장 많이 억제하였으며 Er:YAG 레이저 조사도 산 생성능을 억제하였다. Chinese ink를 사용하지 않고 Nd:YAG 레이저를 단독으로 조사한 경우는 S. mutans의 산 생성능을 억제하지 못하였다. Er:YAG 레이저와 Chinese ink로 photosensitization을 시행한 후 Nd:YAG 레이저를 조사한 경우는 pulse repetition rate가 클수록 전반적으로 세균의 산생성능을 더 많이 억제하였다. 3. 레이저 조사는 S. mutans의 불용성 세포외다당류의 합성에 영향을 미치지 못하였다. 이상의 결과로 보아 Er:YAG 레이저와 Chinese ink로 photosensitization을 시행한 후의 Nd:YAG 레이저 조사는 일정시간 동안 S. mutans의 증식과 산 생성능을 억제시키므로써 치아우식증 예방효과를 얻을 수 있다고 사료되나 억제효과가 오래가지 않아 임상적으로 효과를 얻기 위해서는 자주 조사를 해주어야 한다는 문제점을 안고 있어 임상적으로 치아우식증 예방이란 단독 목적으로 사용하기에는 실용성이 크지 않다고 사료된다. This was performed to evaluate the inhibitory effect of laser on the growth of S. mutans. The bacterial pallets containing S. mutans KCTC 3065 were irradiated with Er:YAG laser and Nd:YAG laser by non-contact method at an intensity of 50mJ for 5 sec with the pulse repetition rates of 10Hz and 30Hz, respectively. The following results were obtained on colony count, acid producing ability, and the amount of insoluble extracellular polysaccharide synthesis. 1. The irradiation of Nd:YAG laser after photosensitization with Chinese ink inhibited the proliferation of S. mutans the most, and the irradiation of Er:YAG also inhibited the proliferation. However, the irradiation of Nd:YAG laser alone could not inhibited the proliferation of S. mutans. The pulse repetition rate did not affect significantly on the proliferation of bacteria in overall. 2. The irradiation of Nd:YAG laser after the photosensitization with Chinese ink inhibited the acid production of S. mutans the most for a certain period of time. Er:YAG laser also inhibited acid production. When Nd:YAG laser was used alone, the acid production of S. mutans was not been inhibited. The irradiation of Nd:YAG laser after photosensitization with Chinese ink inhibited the acid production ability of bacteria the most as the pulse repetition rate increased. 3. Laser irradiation did not inhibited the synthesis of insoluble extracellular polysaccharide of S. mutans. From these results, we conclude that the irradiatioin of Er:YAG laser and Nd:YAG laser after photosensitization with Chinese ink would inhibit the proliferation and acid production by S. mutans, which may prenent dental caries. However, this effect does not last long time so that the laser irradiation should be repeated frequently in order to obtain clinical effect; thus, this laser irradiation would not have a clinical usefulness in preventing dental caries when used solely.
A FERROELECTRIC BASED PASSIVE RFID TAG FOR UHF (860-960 MHz) BAND
Kang, Hee-Bok,Hong, Suk-Kyoung,Park, Hae-Chan,Chang, Heon-Yong,Park, Kun-Woo,Ahn, Jin-Hong,Kih, Joong-Sik,Sung, Man Young,Sung, Young-Kwon Taylor Francis 2007 Integrated ferroelectrics Vol.89 No.1
<P> For a longer working distance between passive tags and the reader, the ferroelectric based technologies are proposed in UHF (860-960 MHz) band transponder. The small ferroelectric capacitor layout area with a stacked capacitor structure over circuit region and a large dielectric permittivity of 250 to 500 and small 1T1C cell array layout area with simple 2T2C based reference scheme allow small chip size. The low operation voltage of 1.5 V to 2.0 V without high voltage boosting scheme also contribute to small power consumption and low cost.</P>
Convergence Diagnostics for the Gibbs Sampler
Joong Kweon Sohn,Heon Joo Kim,Sang Gil Kang 한국데이터정보과학회 1996 한국데이터정보과학회지 Vol.7 No.1
The Gibbs sampler is a substantially powerful tool in Bayesian analysis. However, it is necessary to choose the number of iterations and the size of random samples. This problem has been studied by many researchers. The proposed procedures by them are generally difficult to apply to a practical problem. The attraction of the sampling based approaches is their conceptual simplicity and ease of implementation for users with available computing resources but without numerical analytic efforts. In this paper we consider the problem of determining the number of iterations t, which is simple to application.
강익중,이도헌 한국공업화학회 2002 응용화학 Vol.6 No.1
Many studies have demonstrated that nanoparticles are effective, safe absorption enhancers to improve the delivery efficiency of drug and vaccine, and suitable for controlled drug release because it has stability, bioadaptability and biodegradability. The experiment was performed in vivo by utilizing chitosan nanoparticles as a biopolymer to control drug delivery rate at an optimal temperature, pH, and concentration. It was observed that nanoparticle containing insulin could effectively control the blood glucose to low level.
Kang, Jin Ku,Chang, Chang-Hyun,Nam, Hyo Jung,Kim, Sung-Kuk,Ahn, Keun Jae,Seok, Heon,Park, Sang Joon,Kang, Yoon Joong,Jo, Young Suk,Shong, Minho,Kim, Ho IOS Press 2011 Cellular oncology Vol.34 No.1
<P>Phospholipase C-관l (PLC-관l) is known to play a critical role in cell adhesion and migration and is highly expressed in metastatic tumors. In the current study, we found that cells transformed by PLC overexpression (PLC-관l cells) exhibited a marked decrease in expression of the Epo receptor (EpoR). Here, we assessed the role of EpoR-dependent signaling pathways in PLC-관l-dependent regulation of cell adhesion and migration.</P>
BAYESIAN ESTIMATION PROCEDURES IN MULTIPROCESS DISCOUNT NORMAL MODEL
Joong Kweon Sohn,Sang Gil Kang,Heon Joo Kim 한국데이터정보과학회 1995 한국데이터정보과학회지 Vol.6 No.2
A model used in the past may be altered at will in modeling for the future. For this situatiom, the multiprocess dynamic model provides a general framework. In this paper we consider the multiprocess discount normal model with parameters having a time dependent non-linear structure. This model has nice properties such as insensitivity to outliers and quick reaction to abrupt changes of pattern.