大邱 都心部再開發事業의 改善方案에 關한 硏究

尹炳九,金正煥 啓明大學校 産業技術硏究所 1988 産業技術硏究所 論文報告集 Vol.10 No.-

The future will confront us with other tasks, probably even lager assignments for urban planning. There will have to be a gradual intergration of "urban renewal planning" into the scope of encompassing urban planning measures. Urban renewal planning is a task for many branches of science. This study attempted to pressent the concepts and objectives of urban renewal planning for CBD Daegu and describe the legal foundations, Preparatory work. excution and financing.

여성에서 황체호르몬과 골다공증

윤병구 대한골대사학회 1995 대한골대사학회지 Vol.2 No.2

한국인에서의 무과립구증 발병율 조사연구 -제4상 임상시험을 위한 기초자료조사-

안윤옥,박병주,이무송,김병국,구홍회,서철원 大韓臨床藥理學會 1993 臨床藥理學會誌 Vol.1 No.1

卯巢腫瘍의 病理學的 檢索

尹 確,金秉憲,李東久 慶北大學校 醫科大學 1975 慶北醫大誌 Vol.22 No.2

1970년부터 1978년까지 만 9년간 경북대학교 의과대학 병리학교실에 의뢰된 난소종양 169예를 검색한 결과 다음과 같은 성적을 얻었다. 난소종양은 총 169예로 양성종양이 124예(73.4%), 악성종양이 45예(26.6%)였으며, 전이암은 9예로 전 난소종양의 4.2%를 차지하였다. 조직학적 유형은 양성낭성기형종이 전 난소종양의 26.6%로 가장 많이 발생하였고, 다음은 양성장액성낭종이 36예(21.3%), 양성점액성남종이 30예(17.8%), 악성장액성종양이 15예(8.7%)의 빈도순이었다. 난소종양의 크기는 총평균이 11.1㎝ 이며, 양성종양의 평균크기는 10.6㎝, 악성종양이 12.7㎝로 나타났으며, 조직학적 유형별로 살펴보면 양성낭성기형종은 9.5㎝, 양성장액성낭종은 11.2㎝, 양성점액성낭종은 14.0㎝, 악성장액성종양은 10.4㎝, 전이암은 13.9㎝이었다. 양성종양의 평균연령은 37세였으며, 악성종양은 43세였다. 전 종양의 11예인 6.5%가 19세 이하였다. 조직학적 유형별로 보면, 양성낭성기형종의 평균연령이 34세였고, 양성장액성낭종이 38세, 양성점액성낭종이 36세, 악성장액성종양이 43세, 전이암이 49세였다. 발생부위를 알 수 있었던 150예의 난소종양은 좌측이 61예(40.7%), 우측예 58예(33.7%)로 좌우편재성은 인정되지 않았으며 양측예는 31예(20.7%)였다. 임상증상은 조직학적 유형에 관계없이 양성 및 악성에서 복부종괴 촉지가 88예(27.8%)로 가장 많았고, 그 다음이 복통 60예(18.7%), 복부불편감 33예(10.4%), 복부팽만이 32예(10.1%), 상부 위장관증상 28예(8.8%), 전신증상 22예(6.9%), 자궁이상출혈 19예(6.0%)의 순위였고, 증상이 나타나지 않는 환자가 35예(11.0%)였다. The author studied the 169 cases of primary and metastatic ovarian tumors, that were submitted to the department of pathology, school of medicine, Kyungpook National University, during the period of 9 years, from 1970 to 1978. The results of the study were summarized as follow: Of the 169 cases of ovarian tumors, 124(73.4%) were benign and 45(26.6%) were malignant. Metastatic tumors were 9 cases(4.2%). In histological type, benign cystic teratoma(45,26.6%)ranked first and followed by benign serous cystadenoma(36, 21.3%), benign mucinous cystade-nma(30, 17.8%) and serous cystadenocarcinoma (15, 8.7%) in order of frequency. Mean size of all ovarian tumors was 11.3cm, that of benign tumors 10.6cm and malignant tumors 12.7cm. Mean age of benign overian tumors was 37 years and malignant one was 43 years. There is observed in 11 cases(6.5%) in the age group under 19 years old. Left side of ovarian tumors was 61 cases(40.7%), right side 58 cases(33.7%) and both sides 31 cases(20.7%). Clinical symptoms were palpable abdominal mass, abdominal pain, abdomial discomport, abdo-minal distension, upper gastrointestinal symptom, general symptom and abnormal uterine bleeding in order of frequency.

Wolff-Parkinson-White 증후군의 외과적 치료 : 초기 10례치험 보고 CLINICAL EXPERIENCE OF INITIAL 10 CASES

장병철,김성순,홍유선,윤치순,방서욱,조범국 대한의학협회 1990 대한의학협회지 Vol.33 No.5

선천성 양측성 폐정맥 협착증의 심초음파 및 심도자 및 혈관조영술 소견

정남식,하종원,윤정한,김병옥,장양수,조승연,조범구 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.4

단독주택지역의 주거환경에 대한 주민만족도에 관한 연구

김철수,임성호,윤병구 계명대학교 산업기술연구소 1998 産業技術硏究所 論文報告集 Vol.21 No.1

The main purpose of this study is to suggest some policy directions for a better residential environment in detached housing area in case of Taegu metropolitan city. In order to consider the change of urban spatial structure, study areas are classified into three zone-CBD, inner zone and outer zone. A field survey is conducted to measure residential satisfaction levels in term of safety, health and convenience. The main findings of this research can be summarized as follows. In general, the level of residential satisfaction at CBD is the worst with the lowest levels of the all three measures, while that of outer zone is the best with some dificiencies in term of health. The major determinants of the levels of residential satisfaction are found out to be (i) privacy protection, public transport, air quality and neighborhood facilities in case of CBD, (ii) cleanliness, fire protection, sunlighting and shopping facilities in case of inner zone, and (iii) public transport in case of outer zone. As is discussed, zonal problem is unique.

주택지 개발유형에 따른 주거환경 만족도와 정주성향에 관한 연구

임성호,손상락,윤병구 계명대학교 산업기술연구소 1998 産業技術硏究所 論文報告集 Vol.21 No.1

This study analyzes the difference of recognition on the dwelling environment satisfaction and the propensity to settlement of residents by dwelling characteristics and their desire and verifies the relations among them. The results are summarized as follows. The dwelling environment satisfaction and the propensity to settlement show the difference according on the development type and the housing type. The residential satisfaction at the detached housing area with housing site exploitation work is appeared higher than to the one at the apartment area with the land adjustment work. The major factors effecting on the propensity to living are Safty and Convenience in the projected area of housing site. while the one effecting on house-moving is Health in the projected area of land adjustment. Finally, To plan new housing area should be considered in several important variables on the dwelling environment according to the development types of residential area in the future.

병원단위의 임상진료지침 개발과정

신영수,김창엽,오병희,한규섭,윤병우,한준구,강영호 한국의료QA학회 1997 한국의료질향상학회지 Vol.4 No.1

Background : With increased concerns about variation among physician a practice pattern and their impact on the quality of care, clinical practice guidelines have been developed by many different organizations, with differing aims and incentives. From the same point of view, there is growing interest in the development of clinical practice guidelines in Korea, but with only a few examples. As a result, there is not much exploration on the incentive and barrier to development guidelines as well as description on the development process. The purposes of this study are to describe the process of the four different clinical practice guidelines in a hospital setting, and to identify incentives and barriers in the development of guidelines. Methods : For this research, a clinical practice guideline development committee and four clinical practice guideline development teams were organized in a university hospital which has more than 1,200 beds. Twenty eight doctors, three nurses, and one technician participated as members of development teams for eight months. Four to six meetings were held, and three to seven departments in the hospital were involved. Results : The topics which developed into clinical practice guidelines were cardiopulmonary resuscitation(CPR), blood transfusion, anticoagulation, and angiography. The main goals set by teams were education(CPR, angiography), risk management(blood transfusion), and to enhance quality of care(anticoagulation). Among four teams, only in the team for anticoagulation guideline medical record review and pilot-testing were performed. Also literature review was not carried out systematically. However, all the guidelines were developed by multidisciplinary participation by personnels of related departments. All the team expected guidelines to be used as standard protocols in the practice. Conclusion : Experience and skill in developing process has to be improved to have a more valid and useful practice guideline. In particular, literature review and problem identification by examining medical record should be emphasized. Also further studies of the clinical outcomes of the guidelines application and changes in physicians behaviors would be required.

Impact of Lysophosphatidylcholine on the Plasminogen Activator System in Cultured Vascular Smooth Muscle Cells

Yoon, Byung-Koo,Kang, Young-Hee,Oh, Won-Jong,Park, Kyungwon,Lee, Dong-Yun,Choi, DooSeok,Kim, Duk-Kyung,Lee, YoungJoo,Rhyu, Mee-Ra The Korean Academy of Medical Sciences 2012 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.27 No.7

<P>The balance between tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) regulates fibrinolysis. PAI-1 expression increases in atherosclerotic arteries and vascular smooth muscle cells (VSMCs) are one of major constituents of atheroma. We investigated the impact of lysophosphatidylcholine (lysoPC), an active component of oxidized low-density lipoprotein, on the plasminogen activator system of the rat VSMCs. The lysoPC stimulated the protein and gene expressions of PAI-1 but did not affect the protein expression of t-PA. Fibrin overlay zymography revealed that lysoPC increased the activity of PAI-1 in the conditioned media, while concurrently decreasing that of free t-PA. Vitamin E inhibited the lysoPC-induced PAI-1 expression. Further, lysoPC increased the intracellular reactive oxygen species (ROS) formation. Caffeic acid phenethyl ester, an inhibitor of NF-κB, blocked this lysoPC effect. Indeed, lysoPC induced the NF-κB-mediated transcriptional activity as measured by luciferase reporter assay. In addition, genistein, an inhibitor of protein-tyrosine kinase (PTK), diminished the lysoPC effect, while 7,12-dimethylbenz[a]anthracene, a stimulator of PTK, stimulated PAI-1 production. In conclusion, lysoPC does not affect t-PA expression but induces PAI-1 expression in the VSMC by mediating NF-κB and the genistein-sensitive PTK signaling pathways via oxidative stress. Importantly, lysoPC stimulates the enzyme activity of PAI-1 and suppresses that of t-PA.</P>