동종이식골의 탈회정도가 이소성 골형성유도에 미치는 영향

윤홍식 慶北大學校 齒科大學 1997 慶北齒大論文集 Vol.14 No.-

동종이식골내의 탈회정도에 따른 잔존 칼슘피가 이소성 골형성능에 미치는 영향을 파악하고자 Sprague-dawley계 백서에서 채취한 경골및 대최골의골간부를 0.5cm크기로 절단하여 부착 연조직은 제거한 다음 초음파 세척장치를 이용하여 60℃ 0.6N HCI용액 5분, 10분, 15분, 20분, 25분, 30분, 35분, 40분간 각각 처리하여 탈회 동종이식골을 준비하였다. 이때 탈회시간에 따른 시편의 무게를 측정하였고, 각 탈회용 액으로부터 1cc를 취한 다음 Sigma사의 진단용 칼슘피 측정 kit를 이용하여 spectrophotometer의 600mm파장하에서 칼슘측정을 시행하였다. 그리고 탈회정도에 따른 이식골편의 골형성 유도능을 확인하기 위하여 24마리의 Sprague-Dawley계 백서를 탈회사간별로 8군으로 나누어 배부에 0.5cm크기로 4군데의 피하낭을 형성한후 각각의 처리된 탈회이식골편을 이식하였다. 매식된 동종이식골편들을 술후 1, 2, 3주째 채취하여 통법에 따라 H-E염색 표본을 제작하여 광학현미경으로 관찰하였다. 이상의 실험에서 다음과 같은 결과를 얻었다. 1. 탈회30분가지의 용출되는 칼슘농도변화가 평균 15.91mg/ml로, 탈회20분 이후에 평균 99.65%의 탈회정도를 보였다. 2. 동종골 무게변화량은 탈회시작 25분까지 뚜렷한 무게변화를 보였으나, 그 이후에는 변화정도가 미약하였다. 3. 탈회된 이식동종골에 의한 이소성골형성 유도능 비교에서 20분에서 30분간 탈회된군에서 가장 양호하였고 그 외의 군에서는 그 정도가 열등하였다. 이상의 결과는 탈회된 동종골에 있어 골형성 유도능을 극대화하기 위해서는 골기질내의 무기성분의 완전한 탈회가 선행되어야 하며 탈회골기질의 변성이 최소화되어야 함을 시사한다.

國産絹雲母의 含有酸化鐵 處理에 關한 硏究 : 溶解速度를 中心으로

洪允命,金雨植,鄭國三 연세대학교 대학원 1977 延世論叢 Vol.14 No.2

This study was carried out to investigate the effect for removal ratio of ferric oxide from the domestic sericite in which was contained 4.44 wt.% of ferric oxide as impurity. Applying the acid treatment with a solution of hydrochloric acid, nitric acid, sulfuric acid and perchloric acid. The removal ratio of ferric oxide was determined by spectrophotometry under the conditions of varying reaction time, concentration and temperature respectively. The following experimental results were obtained on the removal ratio of ferric oxide. i) Removal ratio of ferric oxide have increased in the whole range and shows mort large increasing gap over 55℃, and optimum conditions were obtained when 2N-HCl was treated in the range 85℃, 180min. ii) In the equation of dissolution rate for ferric oxide, *****=k[H+]m' [αA-]n', the constant of anion, n', was determined as 0.60 for Cl-, 0.30 for SO4-2 and 0.29 for NO3-at 25℃, respectively iii) The removal ratio of ferric oxide in the formate to that in the hydrochloric acid solution, R, was related to the reaction temperature, T, such as the of following empirical equation. R = e0.042T

지역경제의 생태학적 평가에 관한 연구 : 낙동강 유역을 중심으로 The case of Nakdong River region, Korea

윤갑식,김홍배,최세호 漢陽大學校 環境工學硏究所 1998 環境科學論文集 Vol.19 No.-

본 연구에서는 수질오염이 산업폐수, 가계하수 그리고 토지유출수의 3가지 요소에 의해서 발생된다는 가정을 바탕으로 환경수준과 경제활동 사이에 존재하는 상반관계를 낙동강유역을 대상으로 분석하였다. 분석에는 다지역 투입산출모형이 이용되는데 이때의 다지역 투입산출표는 행정구역이 아닌 유역권을 기준으로 작성되었고 이를 바탕으로 목표년도(2010)의 낙동강 유역 수질수준을 예측하였다. 또한 수질을 개선하기 위해 두가지 정책 즉, 자체처리시설을 증설하는 정책과 종말처리장을 증설하는 정책을 제시하고 이것을 정책에 소요되는 비용과 정책효과 측면에서 평가하여 지역별 가장 효율적인 정책을 제시하였다. 마지막으로 GRDP에서 수질오염에 의해 발생하는 환경비용을 고려한 ERDP(환경적으로 조정된 지역내 순생산)를 제시하였다. This paper analyzes the trade-off relationship between environmental quality and economic activity, specifically focusing on water pollution of Nakdong-river region, Korea. The analysis begins with the assumption that water is contaminated by three pollutive sources, production sector, household sector and land surface water. Three-region input-output table is constructed based on the Catch basin area not administrative area for analysis. Water polluting level of Nakdong river region in the year 2010 is forecasted taking into account the pollutive sources. Also, two types of environmental policies are presented and assessed in terms of pollution abatement costs and effects. Finally, the interest in this paper stems from recent advances in so-call EDP(environmentally adjusted net domestic product) which reflects environmental costs in GDP. The paper attempts to calculate ERDP(environmentally adjusted net regional domestic product) by incorporating EDP into regional level with the assumption that environmental costs are represented by water pollution abatement costs.

복강암세포(Sarcoma-180)를 이식한 마우스에서 상황버섯(Phellinus linteus) 추출물이 백혈구 화학주성(Chemotaxis)능에 미치는 영향

조홍식,윤정중,이연태 대한암예방학회 1999 Journal of cancer prevention Vol.4 No.4

머리염색이 인체에 미치는 영향

윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

우리나라 재난의학적 처치에 대한 연구 : 1993년 3월 29일 구포 열차 전복사고를 중심으로 한 연구 ANALYSIS OF RAILROAD COLLAPSED ACCIDENT OF GUPO

백광제,홍윤식 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Disaster in an unexpected, chaotic, horrendous catastrophes and it may be either natural or human origin. Now a days, disasters are occurring at on increasing rate due to population growth and technological advancement. Medical disaster in an incident which produces such a number of causalities that makes the routine methods for patient care ar4e inadequate. The public no linger accept these consequences as "act of God" and they demand that disaster risks to be minimized and that any impact to be management in an orderly fashion. So emergency medical personnel must strive to achieve themselves to achieve the greatest good for the greatest number of potential survivors at the disaster scene. On 28 March 1993, a train carrying 600 passengers rolled over due to railroad collapse. About 170 passengers dies(25 before extrication) and 22 severe wounded survived. Problems in the organization at the scene, triage, and the communication contributed to the confusion in the management of victims. As analysis of this accident allows several lessons to be learn which might prevent or reduce the fatalities from future disaster. Although Korean community has relied on a model of disaster response deprived from the experience of military and civil defense planners for years. A better approach to organizing medical personnel for the incident with multiple causalities, which is based on the medical response of the emergency medical services organization, will be needed in the near future.

HFCVD법을 이용하여 제작한 n-형 다이아몬드 박막의 특성 연구

김병규,황윤식,권민철,김용,이재열,박홍준 동아대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.17 No.1

HFCVD법으로 암모니아 가스를 사용하여 n-형 도핑된 다이아몬드 박막을 제작하여, 기판온도와 암모니아 가스 첨가비에 따른 박막의 morphology의 변화를 조사하였다. 증착된 시료에 대한 SEM, Raman, XRD를 이용하여 박막의 특성을 분석하고, 도핑에 따른 전계방출 특성을 측정하였다. 양질의 n-형 도핑된 다이아몬드 박막을 증착시키기 위해 기판온도와 암모니아 첨가비에 따른 최적의 증착조건을 찾을 수 있었다. We fabricate n-doped diamond thin films by hot filament chemical vapor deposition method(HFCVD) using ammonia as a doping gas and investigate the effect of the substrate temperature and the ammonia gas ratio upon the diamond film morphology. The SEM, Raman spectroscopy, and the XRD analysis are executed to characterize film morphology. Field emission property of the film is measured also. We find optimum conditions of the substrate temperature and the ammonia gas ratio to deposit high quality n-doped diamond thin films.

응급센터에 내원한 만성 폐쇄성 폐질환 환자에 대한 고찰

박승회,백광제,홍윤식 대한응급의학회 1993 대한응급의학회지 Vol.4 No.2

Chronic Obstrcitive Pulmonary Diseases(COPDs) produce significant morbvidity and mortality in human lives. COPD is a progressive disease that coexists with emphysema and chronic brochitis. The critical episodes depend on inciting or aggravating factors which can be classified into 3 ways. First, disease related aggravation. Second, Patient related aggravation. Third, Physician related(latrogenic). The authors reviewed 102 COPD patients who came to Korea University Hospital Emergency Medical center from March of 1992 to February of 1993. 1) Males were more frequently affected than females, and male to female ratio was 2.64 : 1 2) The average age of the patients were 62.8 years old. 3) The average number of hospital admission was 2.5 times and one patient was admitted 9 times for the same disease. 4) On an average, the patients had dyspneic symptoms for 15.6 years and the symptoms had developed since they were 47.8 years old. 5) The ratio between smokers and nonsmokers were3 2.1 : 1, the smokers had smoked for 36.3 years and the average amount of smoking was 1.5 pack per day. 6) After admission, sputum culture and sensitiveity test were done and the results were as follows : nonspceific organums 47 cases(46.0%), streptococcus 23 cases(22.5%), Pseudomonas 15 cases(14.7%), Hemophilus influenza 7 cases(6.8%), Klebsiella 5 cases(4.9%), Actinomycosis 3 cases (2.9%), Staphylococcus 2 cases(1.9%) 7) Aggravation factors for dyspnea were as follows : Upper Respiratory Tract Infection 40 cases(39.2%), Smoking 2.5 cases(24.5%), Pneumothorax 11 cases(10.8%), Pneumonia 7 cases(6.8%), Unknown origin 19 cases(18.6\%) 8) Prognosis after hospital admission were classified into 6 groups : 1. completely recovered 2. almost recovered 3. no improvement 4. hopeless discharge 5. expired within 48 hrs. 6. expired after 48hrs. The results were as follows : 87.3%(89 cases) discharged in almost recovered stated state, 1.9%(2 cases) discharged with no improvement, 4.9%(5 cases) were hoplessly discharged, 2.9%(3 cases) expired within 48 hrs, 2.9%(3 cases) expired after 48 hrs.

컬럼형 회분건조기를 이용한 벼의 건조에 관한 연구

변유량,최홍식,조형용,권윤중,김주봉 연세대학교 산업기술연구소 1984 논문집 Vol.16 No.1

The vertical column batch dryer which is suitable to Korean farm was constructed and dryer performance was investigated through field test. The effect of a drying air temperature and an airflow rate on the drying rate was studied, and an empirical drying equation was established. The average drying rate of paddy were 1.6-1.8%/hr at the air temperature of 43℃ and the airflow rates of 19.4 - 24.5 CFM/ft². The differences of grain moisture content between the inner and outer layer of vertical paddy bed were 0.5 - 0.9% The effect of a drying air temperature was larger at high airflow rate. At constant temperature, the drying rate was increased as an airflow rate was increased. The empirical drying equation could be expressed as followed: ??=0.9exp(??) Where K=3.22×?? The average whitening ratio of brown rice which was dried with column batch dryer was higher 0.6% than that of sun dried rice.

MHD WAVE ENERGY FLUXES GENERATED FROM CONVECTION ZONES OF LATE TYPE STARS

Moon, Yong-Jae,Yun, Hong-Sik The Korean Astronomical Society 1991 Journal of The Korean Astronomical Society Vol.24 No.2

An attempt has been made to examine the characteristics of acoustic and MHD waves generated in stellar convection zones($4000\;K\;{\leq}\;T_{eff}\;{\leq}\;7000\;K$, $3\;{\leq}\;\log\;g\;{\leq}\;4.5$). With the use of wave generation theories formulated for acoustic waves by Stein (1967), for MHD body waves by Musielak and Rosner (1987, 1988) and for MHD tube waves by Musielak et al.(l989a, 1989b), the energy fluxes are calculated and their dependence on effective temperature, surface gravity and megnetic field strength are analyzed by optimization techniques. In computing magneto-convection models, the effect of magnetic fields on the efficiency of convection has been taking into account by extrapolating it from Yun's sunspot models(1968; 1970). Our study shows that acoustic wave fluxes are dominant in F and G stars, while the MHD waves dominant in K and M stars, and that the MHD wave fluxes vary as $T_{eff}^4{\sim}T_{eff}^7$ in contrast to the acoustic fluxes, as $T_{eff}^{10}$. The gravity dependence, on the other hand, is found to be relatively weak; the acoustic wave fluxes ${\varpropto}\;g^{-0.5}$, the longitudinal tube wave fluxes ${\varpropto}\;g^{0.3}$ and the transverse tube wave fluxes ${\varpropto}\;g^{0.3}$. In the case of the MHD body waves their gravity dependence is found to be nearly negligible. Finally we assesed the computed energy fluxes by comparing them with the observed fluxes $F_{ob}$ of CIV(${\lambda}1549$) lines and soft X-rays for selected main sequence stars. When we scaled the corrected wave fluxes down to $F_{ob}$, it is found that these slopes are almost in line with each other.