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      • KCI등재

        In-pile tritium release behavior and the post-irradiation experiments of Li4SiO4 fabricated by melting process

        Zhao Linjie,Yang Mao,Xiao Chengjian,Gong Yu,Ran Guangming,Chen Xiaojun,Li Jiamao,Yue Lei,Chen Chao,Hou Jingwei,Wang Heyi,Long Xinggui,Peng Shuming 한국원자력학회 2024 Nuclear Engineering and Technology Vol.56 No.1

        Understanding the tritium release and retention behavior of candidate tritium breeder materials is crucial for breeder blanket design. Recently, a melt spraying process was developed to prepare Li4SiO4 pebbles, which were subsequently subjected to the in-pile tritium production and extraction platform in China Mianyang Research Reactor (CMRR) to investigate their in-situ tritium release behavior and irradiation performance. The results demonstrate that HT is the main tritium release form, and adding hydrogen to the purge gas reduces tritium retention while increasing the HT percent in the purge gas. Post-irradiation experiments reveal that the irradiated pebbles darken in color and their grains swell, but the mechanical properties remain largely unchanged. It is concluded that the tritium residence time of Li4SiO4 made by melt spraying method at 467 ◦C is approximately 23.34 h. High-density Li4SiO4 pebbles exhibit tritium release at relatively low temperatures (<600 ◦C) that is mainly controlled by bulk diffusion. The diffusion coefficient at 525 ◦C and 550 ◦C is 1.19 × 10 11 cm2/s and 5.34 × 10 11 cm2/s, respectively, with corresponding tritium residence times of 21.3 hours and 4.7 hours.

      • KCI등재

        The preparation, performance and lithiation mechanism of cobalt-doped zinc oxide as a high performance anode material for LIB

        Yue Li,WanWan Li,Minhua Fang,XiaoLin Yao,Chao Chen,Miao Shui,Jie Shu,Yuanlong Ren 한국물리학회 2017 Current Applied Physics Vol.17 No.8

        Zn1-xCoxO (0 x 0.15) anode material was prepared by an easy polyacrylamide assisted sol-gel route. The successful replacement of Zinc by Cobalt within Cobalt content x 0.09 was confirmed by structural characterization. The introduction of Cobalt element greatly improved the electro-chemical performances of the matrix Zinc oxide. Without carbon coating, at the 20th cycle, Zn0.91Co0.09O anode still preserved a capacity a little bit more than 1000 mA h g1 and a capacity more than 600 mA h g1 was retained at the end of the 50th cycle. Better rate capability was also witnessed. The SEM, EIS at OCV, CV and in situ XRD were further carried out to elucidate the lithiation mechanism. The role Cobalt doping played can be summarized as follows: the stabilization of the Li2Zn phase, the minimization of charge transfer resistance and the enhanced reversibility of the reduction from metal oxide to metal.

      • KCI등재

        Membrane technologies for Li+/Mg2+ separation from salt-lake brines and seawater: A comprehensive review

        Ye Zhang,Li Wang,Wei Sun,Yue-hua Hu,Honghu Tang 한국공업화학회 2020 Journal of Industrial and Engineering Chemistry Vol.81 No.-

        Recent years have seen rapid improvement of technology and large-scale applications of lithium-ionbatteries, which leads to an increasing market demand for lithium. Since the land lithium resources arediminishing drastically, the sources of lithium extraction have shifted to the large amount of waterresources containing salt-lake brines and seawater. Among the varieties of aqueous recovery approaches,membrane technology seems to have huge development potential and good application prospect. This isbecause the membrane technologies exhibit excellent Li/Mg separation selectivity, with low energyconsumption and green process owing to no addition of chemicals. The present work reviews the latestadvances in various membrane technologies, including nanofiltration membrane, electrodialysis,membrane capacitive deionization approaches, solid electrolyte electrolysis-based technology, etc. Therecent developments in positively charged nanofiltration membrane are discussed in terms of thepreparation methods, membrane properties, and Li/Mg separation coefficient. In addition, the effects ofseveral factors on electrodialysis for lithium extraction and relevant mechanisms in both simple andactual saline systems are discussed, including applied voltage, VC/VD, and coexisting ions. Theapplications of electrodialysis with novel selective membrane involving nanofiltration membrane as wellas solid electrolyte membrane and perspectives for further investigation are proposed.

      • KCI등재

        Identification and characterization of heat shock proteins in a parasitic wasp Chouioia cuneae (Hymenoptera: Eulophidae)

        Li‐Na Pan,Feng-ZhuWANG,Xin-Yue ZHANG,Yan-Ni ZHAO,Geng-Ping ZHU,Min LI 한국곤충학회 2018 Entomological Research Vol.48 No.3

        Heat shock proteins (HSPs) are known to be induced in response to various stress factors. Although HSPs have been studied in a number of insects, not much is known about HSPs in the natural enemies of insects, especially parasitoids. In this study, we identified and characterized five full‐length HSP genes (Cchsp40, Cchsp60, Cchsp70, Cchsp83, and Cchsp90) from an endoparasitic chalcid wasp, Chouioia cunea, which parasitizes the fall webworm, Hyphantria cunea pupae, a worldwide pest. The expression of Cchsps in response to temperature, pesticide stresses and UV radiation were also investigated by quantitative real‐time polymerase chain reaction (RT‐qPCR). The results showed that all five Cchsps were induced in response to hot and cold temperatures. Four pesticides induced the abundant expression of Cchsp70, Cchsp83 and Cchsp90 while ultraviolet radiation up‐regulated Cchsp40, Cchsp70, Cchsp83 and Cchsp90. These results indicate the different transcriptional profiles of the five different Cchsps in response to various abiotic stresses. The findings of this study provide insights into the response of C. cunea to abiotic stresses and insight into the use of this parasitoid in biological control strategies.

      • Impact of high-temperature-water cooling damage on the mechanical properties of concrete

        Zhai, Yue,Li, Yan,Li, Yubai,Wang, Siwei,Liu, Yi,Song, Ki-Il Elsevier 2019 Construction & building materials Vol.215 No.-

        <P><B>Abstract</B></P> <P>A series of impact tests were conducted on split Hopkinson pressure bar equipment to study the influence of high-temperature-cooling damage on the mechanical properties of concrete. The experimental investigation showed the influence on the peak stress, peak strain, and fracture mode. The results indicate that the strain rate is directly related to the loading rate and heating temperature. The test results of natural cooling and water immersion cooling treatment were compared, which showed that the strength of water-cooled specimens is higher than that of naturally cooled specimens before the heating temperature reaches 400 °C and becomes much lower when the heating temperature is higher than 400 °C. Based on the experimental study, a dynamic non-linear elastic constitutive equation was established using a particle swarm optimization algorithm and an inversion analysis method. These results could provide theoretical references for the design of the ultimate strength of concrete materials for practical applications, such as fire and explosion prevention.</P> <P><B>Highlights</B></P> <P> <UL> <LI> High temperature-cooling damage on mechanical properties for concrete is tested. </LI> <LI> The strain rate is directly related to the loading rate and heating temperature. </LI> <LI> 400 °C can be considered as the threshold of high temperature-water cooling damage. </LI> <LI> Dynamic non-linear elastic constitutive equation is established. </LI> </UL> </P>

      • KCI등재

        《文选》及李善注所涉神话的数据统计与分析

        李立(Li Li),?月(Gu Yue),李炫周(Li Xuan-zhou) 한국중어중문학회 2009 中語中文學 Vol.45 No.-

        In the present study of anthology, even few scholars have been studying the myth involved in Wen Xuan and its annotated version. The results of the studies are still rare, There are over 140 workers poetries with mythological images in over 700 works which included in Wen Xuan, it was 20% of the total. And the above-mentioned 140 poetries, most of which are annotated by Li Shan, richly embellished with quotations and allusions to classical mythology in poems. The Cbu Ci that has been most frequently quoted it, secondarily Shan Hai Jing, thirdly Huai Nan Zi. Zhuang Zi has come in the fourth. A "Book of Myth" in Wen Xuan, which annotated by Li Shan, mentioned case of myth, and The Chu Ci, Shan Hai Jing and Huai Nan Zi from which over 10 types of myth were quoted, just Shan Hai Jing instead of The Chu Ci had held the first position. Of the 48 kinds of myths in the Wen Xuan by Li Shan annotated, "natural myth was the most, followed by the social myth", then "goddess myth", "creation myth" at least, with only three kinds. Most work s of Wen Xuan were recorded in Two Han Wei Jin Southern and Northern Dynasties, most poems with mythological images were also recorded in the same period. According to the above analysis. Two Han Wei Jin Southern and Northern Dynasties, was not only an important period that Chinese ancient myth was developed evolved, but also an important period that mythology and ancient literature linked by a close relationship.

      • SCISCIESCOPUS

        lncRNA Epigenetic Landscape Analysis Identifies <i>EPIC1</i> as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer

        Wang, Zehua,Yang, Bo,Zhang, Min,Guo, Weiwei,Wu, Zhiyuan,Wang, Yue,Jia, Lin,Li, Song,Caesar-Johnson, Samantha J.,Demchok, John A.,Felau, Ina,Kasapi, Melpomeni,Ferguson, Martin L.,Hutter, Carolyn M.,Sof Cell Press 2018 Cancer Cell Vol. No.

        <P><B>Summary</B></P> <P>We characterized the epigenetic landscape of genes encoding long noncoding RNAs (lncRNAs) across 6,475 tumors and 455 cancer cell lines. In stark contrast to the CpG island hypermethylation phenotype in cancer, we observed a recurrent hypomethylation of 1,006 lncRNA genes in cancer, including <I>EPIC1</I> (epigenetically-induced lncRNA1). Overexpression of <I>EPIC1</I> is associated with poor prognosis in luminal B breast cancer patients and enhances tumor growth <I>in vitro</I> and <I>in vivo.</I> Mechanistically, <I>EPIC1</I> promotes cell-cycle progression by interacting with MYC through <I>EPIC1</I>'s 129–283 nt region. <I>EPIC1</I> knockdown reduces the occupancy of MYC to its target genes (e.g., <I>CDKN1A</I>, <I>CCNA2</I>, <I>CDC20</I>, and <I>CDC45</I>). MYC depletion abolishes <I>EPIC1</I>'s regulation of MYC target and luminal breast cancer tumorigenesis <I>in vitro</I> and <I>in vivo</I>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> LncRNAs show a hypomethylation phenotype, in contrast to a CIMP phenotype in cancer </LI> <LI> <I>EPIC1</I> promotes breast tumorigenesis through regulating cancer cell-cycle progression </LI> <LI> <I>EPIC1</I> directly interacts with MYC protein through <I>EPIC1</I>'s 129–283 nt region </LI> <LI> <I>EPIC1</I> regulates MYC targets by enhancing MYC occupancy on its target promoters </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • SCISCIESCOPUS

        Metabolic Regulation of Gene Expression by Histone Lysine β-Hydroxybutyrylation

        Xie, Zhongyu,Zhang, Di,Chung, Dongjun,Tang, Zhanyun,Huang, He,Dai, Lunzhi,Qi, Shankang,Li, Jingya,Colak, Gozde,Chen, Yue,Xia, Chunmei,Peng, Chao,Ruan, Haibin,Kirkey, Matt,Wang, Danli,Jensen, Lindy M. Elsevier 2016 Molecular cell Vol.62 No.2

        <P><B>Summary</B></P> <P>Here we report the identification and verification of a β-hydroxybutyrate-derived protein modification, lysine β-hydroxybutyrylation (Kbhb), as a new type of histone mark. Histone Kbhb marks are dramatically induced in response to elevated β-hydroxybutyrate levels in cultured cells and in livers from mice subjected to prolonged fasting or streptozotocin-induced diabetic ketoacidosis. In total, we identified 44 histone Kbhb sites, a figure comparable to the known number of histone acetylation sites. By ChIP-seq and RNA-seq analysis, we demonstrate that histone Kbhb is a mark enriched in active gene promoters and that the increased H3K9bhb levels that occur during starvation are associated with genes upregulated in starvation-responsive metabolic pathways. Histone β-hydroxybutyrylation thus represents a new epigenetic regulatory mark that couples metabolism to gene expression, offering a new avenue to study chromatin regulation and diverse functions of β-hydroxybutyrate in the context of important human pathophysiological states, including diabetes, epilepsy, and neoplasia.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Lysine β-hydroxybutyrylation (Kbhb) is a new type of histone mark </LI> <LI> 44 non-redundant histone Kbhb sites are identified in human and mouse cells </LI> <LI> Histone Kbhb increases under starvation and STZ-induced ketoacidosis </LI> <LI> Starvation-induced H3K9bhb is associated with active gene expression </LI> </UL> </P> <P><B>Graphical Abstract</B></P> <P>[DISPLAY OMISSION]</P>

      • Pellet injectors for EAST and KSTAR tokamaks

        Vinyar, Igor,Hu, Jiansheng,Park, Soo-Hwan,Lukin, Alexander,Yao, Xinjia,Li, Changzheng,Chen, Yue,Reznichenko, Pavel,Kim, Hong-Tack Elsevier 2017 Fusion engineering and design Vol.124 No.-

        <P><B>Abstract</B></P> <P>The paper presents high frequency pellet injectors developed for edge localized mode mitigation and plasma fuelling of the EAST and KSTAR tokamaks. Each pellet injector is able to inject solid deuterium or hydrogen pellets at steady state mode. Injectors consist of modules including screw extruder cooled by liquid helium and pneumatic punchers for pellet fabrication and acceleration which are optimized to reach maximal injection frequency for specified pellet parameters.</P> <P>The EAST pellet injector is capable of injecting 1.5mm diameter and 1.2–1.8mm length pellets at frequency up to 50Hz with velocities 200–250m/s using two injection modules working in an alternating mode at 25Hz each. Injection reliability over 90% has been confirmed during several cycles of continuous D2 pellet injection at 50Hz. The KSTAR pellet injector has been designed to inject 2mm size pellets at frequency up to 20Hz and velocity 200m/s. Due to improved design of pellet fabrication and acceleration system the world record in continuous injection of 20,164 deuterium pellets (Ø2.0×1.5mm) for 1039s at 20Hz with reliability 97% has been achieved.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 50Hz and 20Hz pellet injectors have been developed for edge localized mode mitigation and steady state plasma fuelling of the EAST and KSTAR tokamaks. </LI> <LI> Innovative pellet fabrication systems have been designed to achieve world record in continuous pellet injection during 1039s at 20Hz with reliability 97%. </LI> <LI> Both pellet injectors have achieved ITER relevant characteristics of plasma fuelling and ELM control. </LI> </UL> </P>

      • Expression of Proteasome Activator REGγ in Human Laryngeal Carcinoma and Associations with Tumor Suppressor Proteins

        Li, Li-Ping,Cheng, Wei-Bo,Li, Hong,Li, Wen,Yang, Hui,Wen, Ding-Hou,Tang, Yue-Di Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.6

        The functional significance of the proteasome activator $REG{\gamma}$ in the regulation of cell proliferation and apoptosis has been recognized. However, pathological contributions to tumor development remain to be elucidated. Both oncogenic proteins and tumor suppressors are targeted by $REG{\gamma}$ for proteasomal degradation. It has been proposed that the role of the $REG{\gamma}$ in the pathogenesis of cancer is cell- and context-specific. In this study, we aimed to explore the potential involvement of $REG{\gamma}$ in laryngeal carcinomas, comparing protein expression in tumor and adjacent tissues by immunohistochemical staining and Western blot analysis. We also characterized the correlation between the expression of $REG{\gamma}$ and the previously identified substrates p53 and p21. We showed that $REG{\gamma}$ was abnormally highly expressed in cancer tissues. Statistical analysis revealed that there was a positive relationship between the level of $REG{\gamma}$ and the expression of p53 and p21. Our study suggests that $REG{\gamma}$ overexpression can facilitate the growth of laryngeal cancer cells.

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