한약재 열수추출물의 항산화 활성 및 Xanthine Oxidase 저해 활성

신유진(Yu-Jin Shin),황정만(Jeong-Man Hwang),이승철(Seung-Cheol Lee) 한국식품영양과학회 2013 한국식품영양과학회지 Vol.42 No.10

통풍 증상을 개선하고 예방 및 치료에 효과를 확인하여 이를 일상생활에 지장을 주지 않고 장기간 쉽게 복용하기에 적합한 식품 소재를 발굴하기 위하여 한의학 및 식품 관련 서적에서 통풍 개선 및 치료 효과가 있어 널리 사용되고 있는 29가지 식용 가능 한약재를 선별하였다. 각 한약재의 열수 추출액의 총 페놀 함량, DPPH 라디칼 소거능, ABTS 라디칼 소거능, xanthine oxidase 저해능을 측정한 결과, 황금 추출액이 가장 높은 활성을 나타내었다. 이상의 결과는 황금 추출액을 주 소재로 하여 항산화능과 통증 개선에 유용한 식품 개발에 활용될 수 있을 것으로 기대된다. In our study, as many as 29 edible medicinal herbs were selected for testing their ability in the effective treatment of gout based on oriental medicine theory. We extracted each medicinal herb (135 g) with 4 L of distilled water at 100~105°C for 210 min. Thereafter, we evaluated both the antioxidant and xanthine oxidase inhibition activities of the extracts obtained. Among all the edible medicinal herbs used in our study, only the extract from Scutellaria baicalensis Georgi (Korean name: hwang-geum) showed (1) the maximum total phenolic content (TPC) (2.25 mg gallic acid equivalent/mL), (2) DPPH radical scavenging activity (94.04%), and (3) xanthine oxidase inhibition activity (87.75%). We also observed that TPC was relatively highly correlated with both the DPPH radical scavenging activity (r=0.63) and xanthine oxidase inhibition activity (r=0.77). Our results suggest that S. baicalensis G. may be a potent antioxidant source for the extraction and development of nutraceuticals that may be utilized for effective treatment of gout.

Dysregulation of the enteric nervous system may play an important role in C3 deficiency-induced constipation in the mid colon of C3 KO mice

Hee Jin Song,Yun Ju Choi,Ji Eun Kim,You Jeong Jin,Yu Jeong Roh,Ayun Seol,Su Jin Lee,Dae Youn Hwang1,2 한국실험동물학회 2023 한국실험동물학회 학술발표대회 논문집 Vol.2023 No.2

과학적 근거 중심 평가를 도입한 마늘의 콜레스테롤 조절 기능성 평가

김인혜;조강진;김진영;황경아;황유진;채유진;엄애선 한양대학교 2010 韓國 生活 科學 硏究 Vol.30 No.1

Garlic (Allium sativum) is used a flavouring agent and a traditional medicine in human history. Numerous studies support the fact that garlic intake may have effect on cholesetrol-lowering. No claims currently have been made about garlic intake and cholesterol-lowering effect with respect to health claim in Korea. The aim of this study was to evaluate the scientific evidence on garlic intake and cholesterol-lowering effect by the scientific evidence-based rating system of Korean Food and Drug Administration for health claim. We carried out a comprehensive search of the Pubmed, EMBASE, Cochrane Library and manual searches of relevant journals for studies between 1955-2009. The search terms were garlic and Allium sativum in combination with cholesterol. Eighteen clinical stidies were included and reviewed to evaluate the strength of evidence that supports a relation between garlic intake and cholesterol-lowering effect. Our results suggests that level of scientific evidence on garlic intake and cholesterol-lowering effect is "other function (II) probable".

포괄수가지불제도 적용에 따른 산부인과 진료수입의 변화

황태연,유병철,정귀언,정수진,김성준,배기택,손혜숙,이종태,전진호,엄상화 인제대학교 2001 仁濟醫學 Vol.22 No.1

Objectives: Under the fee-for-service system, Korean hospitals have been suffering from the worsening profitability caused by law medical care fees. To overcome the difficulties, they have maximized the quantity of medical services and made relatively large investment in developing new medical services using high-priced medical equipment, medicines and medical supplies which were not covered by medical insurance system rather than reduced running costs. Materials and Methods: This study was made to analyze and forecast the revenue change of the department of Obstetrics and gynecology of an university hospital in Seoul, expecting the implementation of DRG system in 2000. Results: The results were as follows : 1.During the first two days of hospitalization. 41% of total medical service fee was occurred, which was thought that most of the check-ups and operations were made during this period. After two days of hospitalization, the new occurrence of medical service fee tended to reduce. 2.Out of total medical service fee, 67% of admission fee was occurred after 5 days of hospitalization. This was because medical service fees in obstetrics and gynecology department occurred during the first 5 days of hospitalization. 3.Out of fees for operation, treatment, medical supplies and blood transfusion. 71% was occurred during the first two days. 4. In case of fees for examination, 50% was occurred during the first two days. 5.A total of 53% of fees for medication and injection was occurred during the first 5 days. Conclusions: By the implementation of the DRG system, the income is forecast to increase by 800 won to 310,000 won by the disease group of obstetrics and gynecology department. To increase hospital income with the implementation of DRG system, the results of this study suggest that examinations should be done at out-patient departments before the hospitalization of patient, the discharge of patient should be noticed in advance to reduce the period of hospitalization, and admission appointment system should be implemented for the immediate operation and delivery.

자동차 차체조립공정설계를 위한 시뮬레이션

황흥석,박태원,조규성,유진식 한국경영과학회 2000 한국경영과학회 학술대회논문집 Vol.- No.1

본 연구에서는 자동차의 차체조립공정설계를 위하여 FACTOR/AIM 및 자체 개발한 생산시스템 성능평가를 위한 시뮬레이션 프로그램을 이용하여 비교 연구하였다. 이를 위하여 먼저 자체에서 개발한 시스템성능 산정 방법으로 초기 해를 구하고 세부 생산라인의 고장 Data와 조립라인의 구성, 운반장비 등의 의 다양한 여건을 고려하기 위하여 FACTOR/AIM을 사용하였다. Data의 분석을 위하여 ExpertFit를 사용하였으며 초기 시스템 모델링 및 Data로 부터 목표 생산시스템을 만족하는 시스템을 단계별로 찾아가는 과정을 사용하여 최적 해를 구하였다. 본 연구에서 분석한 K회사의 경우 목표 생산량 70대/시간을 만족하기 위하여 4 차의 개선을 통하여 71.57대/시간의 생산라인을 구하였다. 본 연구에서 생산조립라인의 공정설계를 위한 시뮬레이션 과정을 실 예를 들어 제시하였으며 다른 제품의 생산공정분서에도 활용 가능하리라 생각된다.

양방향 요소제거법을 이용한 신뢰성 기반 최적설계

유진식,박재용,황승민,임민규,오영규,한석영 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-

This research presents a Reliability-Based Topology Optimization (RBTO) using Bi-directional Evolutionary Structural Optimization (BESO). An actual design involves uncertain conditions such as material property, operational load and dimensional variation. Deterministic Topology Optimization (DTO) is obtained without considering of uncertainties related to the uncertainty parameters. However, RBTO involves evaluation of probabilistic constraints, which can be done in two different ways, the reliability index approach (RIA) and the performance measure approach (PMA). The reliability index approach (RIA) and the performance measure approach (PMA) are adopted to evaluate the probabilistic constraints. In order to apply the BESO method to the RBTO, sensitivity number is defined as the change in the reliability index due to the addition or the removal of the ith element. In the BESO, a mesh-independency filter using nodal variables is used to remove the checkerboard patterns. The optimal topologies of RIA and PMA are obtained very similarly. It is shown that RBTO based on BESO can be effectively applied from the presented examples.

農業用水에 對한 小考

黃龍鎭,李裕根 진주산업대학교 1982 論文集 Vol.20 No.-

This paper is the one with relation to the agricultural useful water, and then I inquired about the vestiges of the water supply constructs in order to control by the our ancestors. Total consumption water quantities were 1144.24mm as a result of investigated to the consumption water quantities in the rice farming. It is 149 hundred millions ㎥ that is necessary for our country now, therefore, we have need for more water than being. A devise of resolving to the problem belongs to de promoting of the water holding in the soil and the construction of multiple dam.

面單位 農村地域의 類型化에 관한 硏究 : 西部慶南을 中心으로 Based on Sobu Kyongnam

愼英喆,李裕根,黃龍鎭 진주산업대학교 1992 論文集 Vol.31 No.-

本 硏究에서는 行政 및 文化生活의 基礎自 治單位인 西部慶南 9개 郡의 100개 面을 標本으로 삼아 因子分析方法등 여러 數理分析技法을 使用하여 村落의 形想를 3개 그룹으로 區分하며 農村地域의 特性을 나타내고 諸 指標를 利用하여 面單位의 農村地域의 土地利用特性과 類型化를 行하였다. 그 結果를 要約하면 다음과 같다. l) 判別된 平野村 25개, 準山村 49개, 山村 20개는 成功化率 94.0%로 3개 그룹으로 效率的인 村落區分이 이루어졌다. 2) 上位 5개 因子의 特性別 地域區分은 제1因子(人口가 많은 평야지대) 제2因子(畜産業이 盛한 地域), 제3因子(農家率이 높은 地域), 제4因子(果樹. 草地造成地域), 제5因子(沓作이 많은 地極)로 區分되었다. 3) 地域의 類型化는 Al類型(53개 面), A2類型(22개 面), B1類型(6개 面), B2類型(2개 面), C1類型(14개 面), C2類型(2개 面),D1類型(1개 面)의 7개 類型으로 區分되었다. 이러한 各 類型別 空間分布의 特性은 該當 農村地域의 地域開發과 關聯된 政策 이나 開發計劃樹立時 그 地域特性에 맞는 發展戰略과 手段이 될 것이다. This study is purposed to investigate the charactristics of using farm land and the classification of the area of rural community in Myo˘n Unit. With materials and methods to study in this paper, Cases and variables are given. The cases of rural settlement in So˘bu Kyo˘ngnam are one hundred. The variables of structure factor are twenty-three. The cases according to analysis are analysised by method of discriminant, factor and cluster analysis. From this study, The results obtained are as follows. 1) The cases of rural settlement are divided three groups by discriminant analysis. There are twenty-five plains, forty-nine Semi plains and twenty Mountain villages in So˘bu Kyo˘ngnam. 2) Five upper factors are analysised factor 1(populous plain), 2(high animal husbandry), 3(high farmhouse rate), 4(frute tree & pasture), 5(rice paddy field) on factor scores by factor analysis. 3) One hundred cases in So˘bu Kyo˘ngnam are classified according to rural settlement. Seven types of classification are the type of A1(53), A2(22), B1(6), B2(2), C1(14), C2(2), D(l).

난소절제 고혈압 백서에서 에스트로겐 투여가 혈관반응성에 미치는 영향

서봉관,최동주,황진용,천일석,이유판 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.4

대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.