관동맥질환에서 저밀도 지단백 입자 크기의 분포

임효영,김인숙,승기배,강동헌,전두수,장기육,박준철,이수영,홍순조,최규보 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.8

논문 : 1920년대 초기 『조선일보』 「문예란」 연구 -발굴과 위상의 구명

박현수 ( Hyun Soo Park ),홍현영 ( Hyun Young Hong ) 민족문학사학회·민족문학사연구소 2015 민족문학사연구 Vol.57 No.-

『조선일보』의 「문예란」은 1921년 7월 4일부터 같은 해 8월 27일까지 『조선일보』1면에 개설되었다. 이 글의 목적은 『조선일보』 「문예란」에 실린 작품들을 발굴, 소개하고, 그 위상을 구명하는 것이다. 「문예란」이 개설되었던 때는 『조선일보』가 23회에 이르는 발매반포금지와 2차례의 정간을 겪고 점차 운영에서 정상을 찾아가던 즈음이었다. 「문예란」은 총 38회 개설되었는데, 시가 21편, 평론이 3편, 기행문이 1편, 수필이 1편 등 모두 26편의 작품이 실렸다. 「문예란」에 글을 수록한 작가는 변영로, 남궁벽, 김억, 박종화, 오상순, 오천석, 김찬영, 현진건 등이다. 변영로는 「문예란」에서 가장 활발한 작품 활동을 했으며 필자들의 교류에서도 중심에 있었다. 그는 진리가 확정된 세계에서 벗어나 불확실성에 투신하는 자세를 새롭게 창출될 문학의 핵심이라고 주장했다. 이 글은 남궁벽이 스스로 ``∼다``체로 번역해 발표한 「별의압흠」, 「말」 등을 소개하는 것을 통해 정본 확정의 문제를 제기했다. 또 작가의 과작을 고려할 때 새롭게 발굴, 소개하는 남궁벽의 시 5편이 지니는 무게 역시 가볍지 않다. 박종화의 시 가운데 「廢園에누어셔」는 「黑房秘曲」에 실린 시와 달리 3장으로 되어 있다. 특히 3장이 당시 박종화의 지우였던 정백, 홍사용 등의 갈등과 관련되어 주목을 필요로 한다. 이 글에서 소개하는 오상순의 두 시 역시 처음 발굴, 소개하는 시들이다. 이들은 어린 시절의 상상력이 깃든 언어를 가장 본질적인 것으로 파악하는 당시 오상순의 문학관을 드러내고 있다. 「문예란」의 필자들은 이미 문단의 승인을 받은 존재들이었다는 점에서 작품들 역시 문학청년 시기의 습작이나 투고작과는 다르다. 또 「문예란」의 필자는 각각의 동인지에 얽매이지 않는 문인들의 네트워크와 문학 활동을 파악할 수 있는 대상이기도 하다. 「문예란」이 지닌 가장 두드러진 의미는 『조선일보』를 비롯해 『동아일보』 『매일일보』 등 당시 신문 미디어에 같은 성격의 지면이 존재하지 않았다는 점에 있다. Literary section in Chosun Ilbo was first open on July 4, 1921 and lasted until on August 27 in the same year. The section was reported on the first page of Chosun Ilbo. The purpose of this article was to discover and introduce the pieces of literary work reported in Chosun Ilbo, and to bring light on the status of its literary section. The time when literary section was established was the moment Chosun Ilbo was returning to normal condition of running business after having twenty three times of prohibition of release and two times of suspension. The number of reported literary section was thirty eight, which included twenty one pieces of poem, three pieces of critique, one piece of travel essay, and one piece of essay. Thus, the total number of reported literary work was twenty six. Writers who participated in the section were as followed : Young-Roh Byun, Byuk Namgung, Uk Kim, Jong-Hwa Park, Sang-Soon Oh, Chun-Seok Oh, Chan-Young Kim and Jin-Gun Hyun. Among them, Young-Roh Byun was the most active writer in the literary section and was in the center of mutual exchange of opinion among the writers. He sought the core of literature in the attitude that was devoted to the uncertainty, which was off the world of concrete truth. This article supposed a question on determination of the formal copies by discovering and introducing the Byul-eui-ap-hem(별의압흠), and Mal(말) which were reported by Byuk. He translated these pieces for himself using style of writing, "∼ da". Moreover, as Namgung was not a prolific writer, the importance of five pieces of poem by Byuk Namgung should not be overlooked. Park`s poem, Lying in the closed garden(廢 園에누어셔), consisted of three chapters compared to that of his, which were issued in Secret songs in a black room(黑房秘曲). Especially, the third chapter of it was related to conflict among his companions, Baek Jung and Sah-Yong Hong. Therefore, it needs to be focused on that chapter. Two pieces of poem by Sang-Soon Oh were introduced for the first time. These represented Oh`s literary view at the moment, which the writer understood the language with childhood imagination as the most essential one. Writers of the literary section had already been approve by the literary circle. For this reason, the pieces reported in the literary section had a different character from their studies or submission before starting their literature career. In addition, the writers were the subject of the network and career activities among the writers who were not bound by literary coterie magazines. The most significant meaning of literary section was that the section with the same character did not exist in Dong-A Ilbo, Maeil Shinbo, or Chosun Ilbo itself. To prove this point, relation between news media and literature in early 1920s was discussed.

유아의 성별, 연령에 따른 체력 특성

전영남,양점홍,김수진,이성민 釜山大學校 附設 體育科學硏究所 2005 體育科學硏究所 論文集 Vol.21 No.2

The purpose of this study is to examine the characteristics of young children's fitness development in accordance with gheir gender and age, providing information necessary for an effective physical education instruction for young children's growth and development. For the purpose, this researcher selected total 257 young children from K Kindergarten located at K-gu in B Metropolitan City who consisted of 73 boys and 45 girls, both of were fully aged 4, and 83 boys and 56 girls, fully aged 5.......

혈소판 감소증 환자에서 대마비와 전신 상태의 급격한 악화 : 급성 대동맥 혈전증 A Case Report of Acute Aortic Thrombosis 증례 보고

이홍기,박훤겸,백홍규,남영수,김영선,김용수 대한혈관외과학회 2002 Vascular Specialist International Vol.18 No.2

Acute aortic occlusion is rare but poses a high mortality and morbidity. Prompt diagnosis and treatment is essential. Typical presentation is rest pain with bilateral absent femoral pulse. When the non-typical symptoms predominate such as paraplegia, acute abdomen or sudden-onset hypertension, diagnosis may be difficult. We experienced a case of acute aortic thrombosis who suddenly developed paraplegia and rapidly deteriorated within several hours. When the paraplegia developed, he was under treatment with heparin and urokinase, was thrombocytopenic, and the femoral arteries were pulsatile. Spinal cord compression due to bleeding complication had to be ruled out. Duplex sonography and lumbar CT scan were not diagnostic. Aortic thrombosis was diagnosed by abdominal CT scan. This case illustrates the need for high suspicion of acute aortic occlusion presenting with paraplegia especially in patients with associated atherosclerotic disease.

Decoding the Modern Fantasy of `White People, Korean` : An Analysis of Images from `the King Young-jo & Jung-jo` to `the open port era`

Min, Soo hong,Kwon, Young Gull 한국색채학회 2006 한국색채학회 학술대회 Vol.2006 No.1

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

Haemophilus influenzae Type b 에 대한 급성 후두염의 치료 경험 2 례

이수영(Soo Young Lee),유상호(Sang Ho Yoo),이기선(Ki Sun Lee),홍미애(Mi Ae Hong),김순남(Soon Nam Kim) 대한소아알레르기호흡기학회 1998 소아알레르기 및 호흡기학회지 Vol.8 No.1

Epiglottitis is an uncommon but potentially life threatening infectious disease in young children. And it is rapidly progressing cellulitis of the epiglottis and adjacent structures that has the potential for causing abrupt, complete airway obstruction. The most common cause of acute epiglottitis is Haemophilius influenzae type b (Hib), therefore in USA, the acute epiglottitis is seen less commonly since the wide spread use of immunization against Hib. In Korea, there has been no report of acute epiglottitis caused by known bacterial organism, and a little investigation of the effects of the immunization against Hib, or Hib related respiratory diseases. In this report, we describe two cases of acute epiglottitis caused by Hib, occurred in non-immunized young-male children admitted to Ajou University Hospital. They had visited to the emergency center of Ajou University hospital with the complaints of acute fever, drooling, dysphagia and severe respiratory difficulties. In both cases, we observed the cherry-red colored, severely swollen epiglottis by the direct laryngoscopic examination. Hib was cultured in blood samples from both two cases, and the patients treated successfully by the 3 days of endotracheal intubation and proper antibiotics therapy without any complications such as pneumonia, meningitis, osteomyelitis, or pericarditis.

만성 B형 간염에서 라미부딘 치료중 발생한 Viral Breakthrough 예의 임상 결과

안수현,장윤정,오성남,최도원,백수정,정원석,최창원,김경오,임형준,조남영,박종재,김재선,박영태,이명석,연종은,변관수,이창홍 대한간학회 2002 Clinical and Molecular Hepatology(대한간학회지) Vol.8 No.4

목적: 만성 B형 간염의 치료 중 발생하는 약제 내성 변이종은 임상적으로는 치료 중 음전되었던 혈청 HBV DNA가 다시 양전되는 viral breakthrough 로 진단할 수 있다. 현재 약제 내성 변이종이 발생했을 경우라도 라미부딘 치료를 계속 유지하는 것을 권장하고 있으나, viral breakthrough 발생 예들의 장기적 임상경과가 아직도 불명확하여 이것을 일반화하기는 어려운 상황이다. 이에 라미부딘 사용 중 viral breakthrough 가 발생한 예들을 대상으로 그 임상경과를 알아보고자 하였다. 대상과 방법: 9개월 이상 라미부딘을 투약한 만성 B형 간염 환자로 viral breakthrough가 발생한 74명을 대상으로 하였다(남/여 54/20, 평균연령 42세). Viral breakthrough 후 혈청 ALT치, 총 빌리루빈치, HBV DNA 역가, HBeAg, anti-HBe를 정기적으로 검사하면서 임상경과를 관찰하였다. Viral breakthrough 후 라미부딘의 투약기간은 평균 13개 월(1-41개월)이었다. 결과: Viral breakthrough 발생후 혈청 ALT치가 정상으로 유지되었던 환자는 8예(11%)에 불과했고 나머지 66예(89%)에서는 ALT치가 증가하였으며, 이중 30예(41%)에서 급성 악화(ALT 정상 상한치의 5배 이상 상승)를 보였다. 급성악화는 viral breakthrough 후 3개월 내에 19예 (63%)에서 발생하여 3개월 내에 발생한 예가 많았으나 12개월 이상 지나서 나타나는 예도 약 20%에서 있었다. 비대상성 악화는 6예에서 관찰되었다. Viral breakthrough 후 급성악화가 일어난 예와 없었던 예의 비교에서 급성악화를 예측할 수 있는 인자는 발견할 수 없었다. Viral breakthrough 후 발견할 수 없었다. Viral breakthrough 후 HBeAg이 음전된 예는 8예(11%)였으나 그 임상경과는 양호하지 않았다. 결론: 만성 B형 간염 환자 에서 라미부딘 투여 중 발생한 viral breakthrough 예 중 상당수에서 급성악화가 발생하였으며, HBeAg 이 소실되더라도 그 임상경과는 양호하지만은 않았다. Viral breakthrough 발생 후 주의 깊은 임상경과 의 관찰이 요구되며, 앞으로 viral breakthrough 후 급성악화 예에 대한 대규모 연구와 적절한 치료방향의 제시가 이루어져야 할 것으로 생각된다. Background/Aims: Long-term lamivudine therapy can induce the emergence of lamivudine resistant hepatitis B virus (HBV) mutants. Clinically emergence of the mutant is expressed by the reappearance of disappeared HBV DNA in serum. Continued lamivudine treatment has been usually recommended in cases of viral breakthrough. However, the clinical outcome in patients with viral breakthrough is not clear. The aim of this study was to investigate the clinical course of chronic hepatitis B patients after viral breakthrough during lamivudine therapy. Methods: A total of 74 patients with chronic hepatitis B who showed viral breakthrough after at least 6 months of lamivudine treatment were included in this study. They had positive HBeAg and HBV DNA before treatment. The median follow-up duration after breakthrough was 13 months. Results: After viral breakthrough, only 8 patients (11%) maintained normal ALT levels and 66 patients (89%) showed elevation of ALT. 30 patients (41%) showed acute exacerbation of hepatitis (ALT increase over five-times upper normal limit). These acute exacerbations occurred within three months after breakthrough in 19 patients (63%). In the cases of acute exacerbation, 6 patients showed decompensated progression such as elevation of serum total bilirubin. One of them died of hepatic failure. A predictive factor for acute exacerbation was not found. HBeAg seroconversion occurred in 8 patients after viral breakthrough but their clinical course was highly variable. Conclusions: Chronic hepatitis B patients who had viral breakthrough during lamivudine therapy should be followed carefully and regularly in mind of potential clinical deterioration. New strategies are needed to manage the cases of acute exacerbation after viral breakthrough.(Korean J Hepatol 2002;8:389-396)

정신분열병에 대한 리스페리돈의 효과 및 안정성

이민수,김용구,김영훈,연병길,오병훈,윤도준,윤진상,이철,정희연,강병조,김광수,김동언,김명정,김상훈,김희철,나철,노승호,민경준,박기창,박두병,백기청,백인호,손봉기,손진욱,양병환,양창국,우행원,이정호,이종범,이홍식,임기영,전태연,정영조,정영철,정인과,정인원,지익성,채정호,한상익,한선호,한진희,서광윤 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

연구목적 : 본 시험의 목적은 임상시험 시작전에 연구자들을 대상으로 PANSS Workshop을 통하여 PANSS, ESRS에 대한 국내에서의 표준화 작업을 구축하고 새로운 정신병 치료제인 리스페리돈의 효과와 안정성을 재확인하여 리스페리돈 사용에 대한 적정화를 이루는데 있다. 연구방법 : 1996년 4월부터 1996년 9월까지 국내 39개 대학병원 정신과에 입원중인 혹은 증상이 악화되어 입원하는 정신분열병 환자 377명을 대상으로 다시설 개방 연구를 시행하였다. 1주일간의 약물 배설기간을 가진후, 리스페리돈을 8주간 투여하였고, 기준점, 1주, 2주, 4주, 그리고 8주후에 평가되었다. 용량은 제1일에는 리스페리돈 1mg씩 1일 2회, 제2일에는 2mg씩 1일 2회, 제3∼7일에는 3mg씩 1일 2회 투여하였다. 이후 환자의 임상상태에 따라 임의로 증량할 수 있으며, 최대 일일 16mg을 초과하지 않도록 하였다. 추체외로 증상을 조절하기 위한 투약을 허용하였다. 임상증상 및 부작용의 평가는 PANSS(Positive and Negative Syndrome Scale), CGI(Clinical Global Impression) 그리고 ESRS(Extrapyramidal Symptom Rating Scale)을 사용하였다. 연구결과 : 377명중 343명(91%)이 8주간의 연구를 완결하였다. 치료 종결시점인 8주후 PANSS 총점수가 20% 이상 호전된 경우를 약물 반응군으로 정의할때, 약물반응군은 81.3%였다. 리스페리돈에 반응하는 예측인자로는 발병연령, 이전의 입원 횟수, 유병기간이 관련 있었다. 리스페리돈은 1주후부터 PANSS양성, 음성, 및 일반정신병리 점수상에 유의한 호전을 보여 효과가 빨랐다. CGI의 경우도 기준점에 비해 1주후부터 유의한 감소를 나타내었다. ESRS의 경우, 파킨슨 평가점수는 기준점과 비교해 투여 1주, 2주, 4주후 유의하게 증가되었다가 8주후 기준점과 차이가 없었다. Dystonia 평가점수는 1주후만 유의한 증가를 보였으며, dyskinesia 평가점수는 유의한 차이가 없었다. 혈압, 맥박수의 생명징후 및 일반 혈액학 검사, 생화학적 검사, 심전도 검사에서 유의한 변화는 없었다. 결 론 : 이상의 다시설 개방 임상 연구를 통해 리스페리돈은 정신분열병 환자에서 양성증상뿐만 아니라 음성증상 및 전반적인 증상에도 효과적인 것으로 사료된다. 보다 명확한 평가를 위해서는 다른 항정신병약물과의 이중맹검 연구가 필요할 것으로 생각되며, 또한 장기적 치료에 대한 평가도 함께 이루어져야 하겠다. Objective : The purpose of this study was to investigate the efficacy and safety of risperidone in the treatment of Korean schizophrenic patients. Method : This multicenter open study included 377 schizophrenic patients drawn from 39 university hospitals. After a wash-out period of 1 week, the schizophrenic patients were treated with risperidone for 8 weeks and evaluated at 5 points ; at baseline, and 1, 2, 4 and 8 weeks of treatment. The dose was increased from 2mg/day(1mg twice daily) to 6mg/day(3mg twice daily) during the first week and adjusted to a maximum of 16mg/day over the next 7 weeks according to the patient's clinical response. Medication to control extrapyramidal symptoms was permitted. The psychiatric and neurological status of the patients was assessed by PANSS, CGI, and ESRS scales. Results : 343(91%) of 377 patients completed the 8-week trial period. Clinical improvement, as defined by a 20% or more reduction in total PANSS score at end point, was shown by 81.3% of patients. The predictors of response to risperidone were associated older age, shorter duration of illness, fewer previous hospitalization. Risperidone had rapid onset of action ; a significant decrease of the total PANSS and three PANSS factor(positive, negative, general), and CGI was already noticed at the end of first week. For the ESRS, parkinsonism rating scores were significantly increased until week 4 comparing with baseline. Dystonia rating scores were significantly increased until week 1, and dyskinesia rating scores were not significantly changed during the study. Laboratory parameters including vital sign, EKG, hematological, and biochemical values showed no significant changes during the trial. Conclusions : This study suggests that risperidone is generally safe and effective against both the positive and negative symptoms in our group of patients.

노인의 Helicobacter pylori 재균율

박주상,홍원선,이영수,이은주,명승재,정훈용,양석균,김진호,민영일 대한노인병학회 2000 Annals of geriatric medicine and research Vol.4 No.3