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황형수,류영국,모영승 원광대학교 2001 論文集 Vol.26 No.-
제어계의 축소 모델을 구하는 방법을 이용하여 Wang등은 다양한 동특성을 갖는 공정들에 대하여 범용적으로 적용할 수 있는 PID 동조 알고리즘을 제안하였다[7]. 그러나 Wang이 제안한 방법은 공정모델에 영점이 존재하지 않는 경우와 Nyquist선도가 -π/2및 -π를 지나는 경우에는 잘 적용이 되지만 공정모델에 영점이 존재하는 경우에는 동조 성능이 만족스럽지 못하였다. 본 논문에서는 공정 모델에 영점이 존재할 경우 Pade 축소법을 응용함으로써 이를 개선한 방법을 제안하였다. 이 방법은 저차 및 고차, 크고 작은 지연시간, 단조롭거나 진동하는 응답등의 다양한 동특성을 갖는 공정들에 범용적으로 적용할 수 있으며, 시뮬레이션을 통하여 이 방법이 다양한 공정에 우수한 특성을 나타냄을 보였다. The PID tuning algorithm which can applied generally to processes with varies dynamic characteristics is proposed by Wang[7]. However, it can be applied well to process model without zeros and with ∠G(jw)=- π/2 and - π point in Nyquist curve, but it gives unsatisfactory tuning performance for processes with zeros and without ∠G(jw)=- π/2 and - π in Nyquist curve. In this paper, the method which improve it using Pade reduction method is proposed. Satisfactory responses can be expected for processes with various dynamics, including those with low or high order, small or large dead time, monotonic or oscillatory responses. Simulation examples are given to show the effectiveness and flexibility of the controller in handling processes of different characteristics.
흰쥐에서 음경발기 평가의 척도로서 음경해면체내압측정술 확립
송윤섭,김용준,이광우,김준모,문기혁,박영호,민영기,유형균,김형건 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.1
Purpose: Because studies about the control of penile erection at the entral nervous system was dependent on the animal experiments, establishment of measuring penile erection is important to evaluate the effects changes at the central nervous system on the penile erection. Intracavernous pressure measurement in rats has been introduced as a suitable index for the evaluation of penile erection but this method is invasive and technically difficult. So, we established the intracavernous pressure measurement in rats as the experimental index for penile erection. Materials and Methods: 42 male adult Sprague-Dawley rats (250-300gm) were divided to saline or papaverine treated group. Rats were placed on a heating table to maintain their body temparature and anesthetized with 50mg/kg of pentobarbital sodium by intraperitoneal injection. A cannula was inserted to the left carotid artery to measure systemic blood pressure. Saline (0.05, 0.1ml), papaverine(0.05, 0.1, 0.25, 0.5, 1.0, 2.0mg) were injected intracavernously via 26 guage needle filled with saline or papaverine which connected to pressure transducer and polygraph was inserted into the corpus cavernosum on one side to inject the drug and to measure intracavernous presure. Results: Properly executed insertion and intracavernous administration produced a instantaneous but transient rise in intracavernous pressure that substantially stabilized and maintained at 5.4±0.4mmHg. Intracavernous pressure and duration of penile blood flow following intracavernous injection of papaverine are increased comared to those of saline. Conclusions: Monitoring intracavernous pressure in rats represents a suitable index for the evaluation of penile erection in small laboratory animals.
우심방 전체를 침범한 진행성 간세포암종에서의 소라페닙 치료
강영모 ( Young Mo Kang ),류수형 ( Soo Hyung Ryu ),이보경 ( Bo Kyung Lee ),고경호 ( Kyoung Ho Ko ),박태영 ( Tae Young Park ),문정섭 ( Jeong Seop Moon ),조선화 ( Seon Hwa Cho ) 대한간암학회 2018 대한간암학회지 Vol.18 No.2
Advanced hepatocellular carcinoma (HCC) with tumor thrombus extending through the hepatic veins, inferior vena cava, and right atrium (RA) is very rare. However, whether active treatments such as radiation, transcatheter arterial chemoembolization, and sorafenib in advanced HCC with RA involvement prolong survival is uncertain. We present a rare case of advanced HCC with tumor thrombus nearly occupying the entire RA that was treated with sorafenib. The patient received 400 mg sorafenib twice daily. However, her liver enzyme levels continued to increase and abdominal computed tomography showed an increase in the tumor size in the liver and RA. In the present case, active treatment with sorafenib was ineffective; thus, palliative care may be more beneficial in advanced HCC with extensive RA involvement. (J Liver Cancer 2018;18:142-145)
A New High-Yielding White Potato Cultivar, "Shinnamjag"
Young Eun Park,Kwan Soo Kim,Hyun Mook Cho,Ji Hong Cho,Jung Yun Yi,Hyo Won Suh,Sung Yeul Kim,Kyoung Yul Ryu,Hyun Joon Kim,Yul Kyun Ahn,Dong Mo Son,Hyun Sook Kim 한국육종학회 2004 한국육종학회지 Vol.36 No.3
Shinnamjag is a round, smooth, white-skinned, and fleshed potato cultivar with erect plant shape and early maturity. It has excellent table quality. Its yields are high, especially with prominent marketable yield compared to Superior, a leading potato cul
Ryu, Je Ho,Jeong, Young-Il,Kim, Hyun Yul,Son, Gyung Mo,Lee, Hye Lim,Chung, Chung-Wook,Chu, Chong Woo,Kang, Dae Hwan American Scientific Publishers 2018 Journal of Nanoscience and Nanotechnology Vol.18 No.2
<P>Nanophotosensitizer composed of methoxy poly(ethylene glycol) (MePEG) and chlorin e6 (Ce6) (abbreviated as Pe6) was synthesized for efficient delivery of Ce6 to the colon cancer cells. Pe6 nanophotosensitizer has small diameter less than 100 nm with spherical shape and core-shell structure. They were activated in aqueous solution while Ce6 was quenched due to its poor aqueous solubility. They showed no intrinsic cytotoxicity against normal cells and colon cancer cells. Pe6 nanophotosensitizers showed enhanced cellular uptake, phototoxicity, and reactive oxygen species (ROS) generation at in vitro cell culture experiment. Furthermore, they showed improved tumor tissue penetration and accumulation in vivo animal studies. We suggested Pe6 nanophotosensitizers as an ideal candidate for PDT of colon cancer.</P>
Young Sup Ahn,Byeong Choon Jeong,Mi Nam Chung,Joon Seol Lee,Yang Ho Oh,Kyung Soo Min,Jong Hyeong Lee,Eun Seok Kim,In Mo Ryu 한국육종학회 2002 한국육종학회지 Vol.34 No.2
Borami' is a new sweetpotato cultivar with light purple flesh developed at the Mokpo Experiment Station, The National Honam Agricultural Experiment Station, RDA. This cultivar was selected from the cross between 'Yamakawamurasaki' and 'Shinmi' in 1994, Se
뇌경색의 진단에서 확산강조 및 T2강조 영상의 유용성 비교
유승,양영모,유인술,김승환,하영록,정성필 대한응급의학회 2002 대한응급의학회지 Vol.13 No.2
Purpose: Diffusion-weighted magnetic resonance imaging (DWI) has been known to visualize hyperacute ischemic stroke. And it takes only a few minutes to do. Moreover only a small amount of time and little cost is required to add T2-weighted imaging(T2WI) to DWI. The purpose of this study is to determine the usefulness of T2WI in addition to DWI as a primary imaging modality for patients with suspected ischemic stroke. Methods: DWI plus T2WI was performed from January to May 2001 on the patients with suspected ischemic stroke. Two emergency physicians reviewed the films and medical records. The sensitivity and the specificity of DWI and T2WI for acute ischemic stroke were calculated. The agreement between DWI and T2WI was calculated using kappa statistics. Results: A total of 241 patients were enrolled. Acute ischemic stroke was confirmed in 86 (35.7%) patients. The sensitivity and the specificity of DWI for acute ischemic stroke were 94.2% and 98.7%, and those for T2WI were 60.5% and 94.2% respectively. The kappa value was 0.721 (p<0.01). Among the 86 acuted ischemic stroke patients, the number of cases who presented less than 6 hours after symptom onset was significantly lower in the T2WI positive group (31% vs. 68.7%, p<0.05). Conclusion: This study suggests that the addition of T2WI to DWI. as a primary imaging modality for acute ischemic stroke has little benefit compared to DWI alone, especially, when the symptom duration has been less than 6 hours.