흰쥐 시상에서 Epidermal growth factor receptor면역반응 신경세포의 생후 발달에 관한 연구

박영란,정윤영,김종중,문정석,오재욱,정영욱,김주수 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : Epidermal growth factor receptor (EGFR), a 170-kDa transmembrane glycoprotein, appears to mediate epidermal growth factor (EGF) activity. Transforming growth factor-α and EGF produce their biological effects in numerous systems by stimulating the EGFR In this study, we examine the postnatal development of EGFR immunoreactivity in the different regions of the thalamus of the rat Materials and Methods : The present study is based on 28 postnatal cases of rat thalamus ranging from the day of birth, postnatal day 0 (P0) to 30 days (P3, P5, P10, P15, P20, P30), and these cases were compared with adult rat thalamus. Cryostat sections were processed free-floating with monoclonal antibody by immunohistochemistry Results : EGFR immunoreactivity in the thalamus of the rat showed very different patterns according to postnatal ages and thalamic areas. EGFR-immunoreactive cells appeared in the first two postnatal weeks, except the ventral posterior thalamic nuclei. In the early postnatal days, EGFR-immunoreactive cells appeared thalamic midline structures, increased progressively in the first two postnatal weeks, and followed mediolateral gradient. The mature patterns of EGFR-immunoreactive cells were achieved at P20 Conclusion : These data indicate that the maturation of EGFR-immunoreactive cells requires a relatively prolonged period of time to achieve an adult configuration. Many growth factors probably play protective or neurotrophic roles at EGFR-immunoreactive neurons of thalamus both young and adult rats In addition to difference in time of appearance in thalamic nuclei and developing pattern with mediolateral gradient suggest that EGFR-immunoreactivities are correlated with the appearance of the related functional.

심혈관계 질환으로 관상질환 집중치료실에 입원한 환자들의 혜후 측정을 위한 APACHEⅢ점수 체계의 임상적 유용성

이공섭,이창선,최현주,홍종서,강지향,김도형,이민영,오인균,김병엽,김상억,김학찬,한승혜,이재용,지영우,안경주 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

화용론과 전제

오주영 慶星大學校 1987 부산수산대학 논문집 Vol.8 No.4

Although a great number of papers on presuppositions have appeared in recent books and journals, we can't explain the concept of presupposition clearly. However, I think that there are two types of definitions for presupposition : one is a semantic notion, defined in terms of truth and consequence, like (1). (1) A sentence A semantically presupposes another sentence B iff: ⒜ if A is true, then B is true. ⒝ if A is false, then B is true. The other concept of presupposition is a pragmatic notion that the speaker or the hearer rather than the sentence he utters, has presupposition. Under the pragmatic notion, presupposition is the condition that a sentence must be uttered sincerely, as (2). (2) An utterance A pragmatically presupposes a proposition B iff A is appropriate only if B is mutually known by participants. Under these concepts of presupposition, the aim of this paper is to propose that pragmatic presupposition is superior to semantic presupposition in explaining the problem of presupposition cancellation and the projection problem for presuppositions, that is, the problem of explaining how the presuppositions of a complex sentence are related to the presuppositions of the clauses it contains. First, let's look at Langendoen and Savin's proposal(1971) to solve the projection problem for presuppositions. According to this proposal, the set of presuppositions of the complex whole is the simple sum of the parts. In other words, if S?? is a complex sentence containing sentences S₁,S₂,···S?? as constituents, then the presuppositions of S??=the presuppositions of S₁+the presuppositions of S₂···+the presuppositions of S??. For example, the complex sentence (3) holds both the presupposition of its antecedent “Fred has been beating Zelda”and the presupposition of its consequent “She has been unfaithful.”So this proposal is called “cumulative hypothesis ”(by Morgan(1969). But the cumulative hypothesis leads to wrong predictions in cases like (4). (3) If Fred has stopped beating Zelda, then Fred no longer resents Zelda's infidelity. (4) If Jack has children, then all of Jack's children are bald. (n 94) the consequent clause presupposes that. John has children. Nevertheless, the conditional as a whole has no such presupposition. Second, let's turn to Karttunen's proposal(1973, 1974, 1977). Karttunen(1973) distinguished between three different types of complementizable predicates, which he called “plugs”, “holes”, and “filters”as follows: (5) a. Plugs : predicates which block off all the presuppositions of the complement sentence b. Holes : predicates which let all the presuppositions of the complement sentence become presuppositions of the matrix sentence c. Filters : predicates which, under certain conditions, cancel some of the presuppositions of the complement But I think this proposal is very good, but imperfect, because there are some counter- examples for this proposal. I will pick out only one counterexample in (6). In (6), predicate ‘tell’belongs to the above plugs, but the complex sentence (6a) presupposes (6b) which is the presupposition of the complement of (6a). (6) a. The mechanic didn't tell me that my car would never run properly again. b. My car used to run properly. Third, in contrast to the prior theory, Gazdar's proposal(1979 a.b) is as follows: ⒜ all the pontential presuppositions of a sentence are generated as a complete set, as in the original Langendoen and Savin's suggestion. So at this stage, the presuppositions of any complex sentence will consist of all the presuppositions of each of its parts. ⒝ Then a cancelling mechanism is brought into play which culls out of this total set of potential presuppositions all those that will survive to become actual presuppositions of a sentence uttered in a particular context. In one word, we can say that sentences will be associated with potential presuppositions, utterances with actual presuppositions. At any rate, I think Gazdar's proposal has explanatory adequacy and can solve or explain the above problems. In conclusion, semantic theories of presupposition are not viable for the simple reason that semantics is concerned with the specification of invariant stable meanings that can be associated with expressions. Presuppositions are not invariant, not stable, not belong to any orderly semantics, but very changeable to context ; so presuppositions do belong to pragmatics.

슬릿 플레이트 댐퍼를 가진 반강접합부 실험

오상훈,김영주,문태섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2(구조계)

The resistance of a structure against an earthquake is related to its ability to absorb the seismic input energy. The development of devices for dissipating the seismically induced energy on the structure is a subject that is receiving large attention in the field of earthquake engineering. One example of these devices is the steel plate with slits. In this paper, a connection with a slit-type steel plate damper installed at each ends of wide-flange section beam, as an energy absorption element, was proposed. A series of experiment was performed to investigate their behavior and structural characteristic. The main parameters were the aspect ratio of the struts in slit plates, thickness of the struts and height of the vertical places. Test results indicated that most of the energy was absorbed by plastic deformation of slit plate dampers.

토지이용패턴에 따른 하천수질과 식생분포

오영주,강병화,김병우,김성필,한민수,김진호,나영은 한국환경농학회 2006 한국환경농학회지 Vol.25 No.1

급성 충수돌기염의 조기 진단을 위한 초음파검사의 의의

오병연,임경수,이영주,김원,최옥경 大韓應急醫學會 1998 대한응급의학회지 Vol.9 No.4

Background: In the most of emergency department, the diagnosis of appendicitis has been carried by clinical history, physical examination and plain X-ray. But the diagnostic accuracy by these methods was so low that unnecessary operation was common performed, and sometimes the operation was delayed till the physicians could confirm the acute appendicitis clinically. Although many kinds of diagnostic tools such as CT scan, laparoscope, and etc, we believe that ultrasonography(US) would be a quick and sensitive diagnostic method for the evaluation of acute appendicitis in the Emergency Department. Methods: Forty-seven patients who were clinically suspected as acute appendicitis were evaluated with the grayscaled US by emergency physician. The probe of US was placed on maximal tender point of abdomen, and the appendix image was evaluated while probe was pressed deeply and gently. When the blind loop was found at maximal tender point of abdomen, we evaluated the diameter of appendix, the presence of compressibility, peri-appendiceal fluid collection and other mass effect. As soon as the ultrasonographic evidences of the appendicitis were noticed, the operations were done and pathologic report were reviewed later. Results: Among the forty-seven patients, forty patients were diagnosed as a appendicitis by Us, and most common ultrasonic findings were as follows; 1) non-compressible blind loop larger than 5 mm in diameter, 2) wall thickening more than 3 mm, 3) peri-appendiceal fluid collection, 4) periappendiceal mass. Among remaining 7 patients in whom we could not get any positive findings of appendicitis, abdominal CT scan was carried in 2 cases who had direct and rebound tendemess on right lower abdomen, and CT scan showed the evidences of the appendicitis. The other 5 cases without rebound tendemess were observed for 2 hours, and abdominal pain was disappeared lately. Finally forty-two patients were operated and confirmed as acute appendicitis by pathologic reports; 24 were reported as suppurative appendicitis, and 12 cases of gangrenous appendicitis, 3 cases of perforated appendicitis, and 3 cases were peri-appendiceal abscess. The specificity of US in the diagnosis of acute appendicitis was 71.4%, and the sensitivity was 95.2%. Conclusions: In some patients suspected appendicitis, emergency physicians could diagnosis acute appendicitis accurately and rapidly by use of ultrasonography. Although the US was an accurate imaging modality to diagnosis acute appendicitis and evaluate its complications, we recommend a laparotomy or abdominal CT scan in the patients with negative US findings in spite of presence of peritoneal irritation signs such as rebound tenderness and/or muscle guarding on right lower abdomen.

Reactive perforating collagenosis with leukocytoclastic vasculitis

( Ju Yun Woo ),( So Min Lyu ),( Seung Hyun Cheong ),( Ji Yeon Byun ),( Hae Young Choi ),( Chee Won Oh1 ) 대한피부과학회 2012 대한피부과학회 학술발표대회집 Vol.64 No.1

微分方程式의 攝動이 있는 安定性에 관한 硏究

오영선,황정주,안정향 대구대학교 부설 과학교육연구소 1994 과학교육 Vol.7 No.-

Hg₁-xMnxTe산화막의 홀효과에 관한 연구

오재근,최기영,송재흥,김영국,채건식,주유환,설정식,손인호,차성극,이상찬 慶南大學校 附設 基礎科學硏究所 1996 硏究論文集 Vol.8 No.-

HClO₄(pH:2) 수용액에서 양극산화 방법으로 HgMnTe(HMT)의 표면에 산화막을 형성 시켰다. 산화막의 두께는 SEM으로 측정하였으며 10㎛였다. 전류-전압 특성곡선을 얻어 산화 피크 전압으로부터 HTeO₂?, TeO?, HHgO₂? 막이 형성되었음을 알 수 있었다. 산화시키지 않은 HMT와 HClO₄수용액에서 산화시킨 HMT에 대해 Hall전압 및 자기저항을 각각 측정하였다. 홀전압과 자기저항은 HMT보다 HMT산화막에서 더 컸으며 이것은 HHgO₂? 공격자가 홀의 역할을 하고, TeO₄? 산화막은 전하의 포획도를 낮게하기 때문으로 생각할 수 있다. Anodic oxidation processes on HgMnTe surface has been studied in standard aqueous HClO₄(pH:2) solution. The 10㎛ thickness of the anodic oxide layers was measured by SEM. The Composition of the anodic oxide layers are evaluated from current-voltage(I-V) characteristic of HgMnTe Oxidation. The layers are composed of mixed oxide. ??, TeO₄, and?? in HClO₄solution. Transport properties have been investigated in HMT oxide layer made in HClO₄solution and virgin HMT samples at 300K. Hall voltage and magnetoresistance are greater in oxide layer HMT than virgin HMT. As a result, we know that the vacancy of ??in an anodic oxide layer acts as hole and the resulting oxide ?? layer exhibit a reduced degree of charge trapping and increase magnetoresistance.

면접조사를 통한 초등학생의 영양교육 실태 및 실천도 조사

오유진,이영미,김정현,안홍석,김정원,박혜련,서정숙,김경원,권오란,박혜경,이은주,성현이 대한지역사회영양학회 2008 대한지역사회영양학회지 Vol.13 No.4

This study investigated the experience and practice of elementary school students on nutrition education. The data were collected from 217 male and female students attending 5-6th grade elementary schools in Seoul and Kyunggi-Do from March to June 2007, interviewing face to face by a nutrition teacher and 3 interns of a nutrition teacher. The results were as follows: 86.5% of the subjects learned about ‘Table etiquette’, ‘Reasons for eating fruits and vegetables’ (78.7%), ‘Food waste and environment’ (72.3%), ‘Healthy snacks’ (55.7%), ‘Food sanitation’ (52.3%), ‘Food culture of foreign countries’ (48.1%). Nutrition education experience was significantly different by gender. A total of 43.5% boys responded that they never learned about ‘basic food preperation’ (p < 0.01). They had learned ‘Nutrients for body’ and ‘Food waste and environment’ in school, ‘Healthy weight loss’, ‘Food culture of foreign countries’, ‘Food circulation’ on television, Most content (‘Table etiquette’, ‘Simple cooking’, ‘Food sanitati n’, ‘Eating behaviors for health’, ‘Reasons for eating fruits and vegetables’, ‘Healthy snacks’) was learned from parents. The practice after nutrition education was higher in ‘Table etiquette’ (2.14), ‘Eating fruits and vegetables’ (2.07) than others compared with education experience. The most reason of non-practice on nutrition information was ‘Troublesome’. In ‘Nutrients for body’, a boy answered ‘Difficult for practice’ 20.0%, a girl answered ‘Difficult to understand’ 32.6%, showing a significant difference between the gender groups (p < 0.001). They remembered the ‘Nutrients for body’ (49.6%), ‘Food sanitation’ (44.5%) because of ‘important content’,‘Basic food preparation’ (40.6%), ‘Food culture of foreign countries’ (36.3%) because of ‘interesting content’, ‘Healthy weight loss’ (52.0%), ‘Eating behavior for health’ (44.5%) and ‘Healthy snacks’ (33.7%) because of ‘need for my health’.