증폭(蒸曝)에 의한 지황(地黃)의 성분 변화에 대한 고찰

정재우 ( Jae Woo Jung ),김한영 ( Han Young Kim ),류지효 ( Ji Hyo Lyu ),김정훈 ( Jung-hoon Kim ) 대한본초학회 2021 大韓本草學會誌 Vol.36 No.6

Objectives : ‘Steaming and drying’ is a traditional processing method that has been used to produce Suk-ji-hwang (熟地黃; Rehmanniae Radix Preparata) from Ji-hwang (地黃, the fresh root of Rehmannia glutinosa Liboschitz ex Steudel; Rehmanniae Radix). The steaming and drying process, which is proceeded in heating and moisturizing conditions, plays a crucial role in the change of therapeutic effect of Ji-hwang, presumably due to the modification of its chemical constituents. In this article, the chemical influence of the ‘Steaming and drying’ process was investigated for understanding the underlying mechanism of chemical modification of Ji-hwang. Methods : The articles regarding the modifications of chemical constituents of Ji-hwang during the ‘Steaming and drying’ process were collected and analyzed to investigate the influence of the processing to Ji-hwang. Results : The results indicated that iridoid glycosides were degraded to their aglycones and sugars, and such degradations occurred faster at a high pressure than at an atmospheric pressure during the process. The contents of catalpol, ajugol, and acteoside were decreased, while those of rehmannioside A and D were slightly increased during the repeated processing. The contents of oligosaccharides, namely sucrose, maltose, raffinose, and stachyose (except for manninotriose), were decreased, while those of monosaccharides, glucose and fructose, were increased by the repeated processing. Conclusions : These results demonstrate that the ‘Steaming and drying’ process influenced the chemical constituents of Ji-hwang and provide probable basis for the therapeutic modification of Suk-ji-hwang after the processing of Ji-hwang.

골수염으로 발현된 재발성 콕시디오이데스 진균증 1예

백지현,박은영,정윤숙,홍재원,채윤태,진성준,최희경,신소연,한상훈,진범식,김창오,최준용,송영구,조남훈,김준명 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Coccidioidomycosis is a fungal infection that results from inhaling the airborne arthroconidia of the Coccidioides species. It is an endemic disease in the southwest part of North America and rarely diagnosed in Korea. As tourism to endemic areas and the number of immunocompromised patients have been increasing, the incidence of this infection has increased in non-endemic areas. Treatment is usually successful with antifungal agents; however, recurrence is common. It is difficult to decide when to discontinue the antifungal treatment especially in non-endemic areas where doctors are not familiar with the disease. We report a case of recurrent coccidioidomycosis manifesting as osteomyelitis after the treatment of the patient for disseminated coccidioidal infection. The complement fixation test was a useful tool for the assessment of patient response and to evaluate suspected recurrence.

허혈성 심질환에서 나타나는 황상화지수, 사이토카인 및 염증지표의 변화

전상훈,안지훈,방덕원,온영근,현민수,김성구,권영주 순천향대학교 의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

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성장기 아동의 single tooth scissors bite의 교정 치료: 증례 보고

김지인,현홍근,김영재,김정욱,장기택,이상훈,한세현,김종철 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

A scissors bite in the posterior teeth occurs when the upper teeth are positioned totally buccal to the lower teeth in centric occlusion, either unilaterally or bilaterally. This malocclusion can result from either excessive width of the maxilla or deficient width of the mandible, or sometimes combination of the both. Scissors bite, when left untreated without a proper dental intervention, interferes with the normal mandibular growth leading to a state where consequent disharmony in dental arch width evokes occlusal disturbances. Therefore, early preventive orthodontic treatment is necessary in patients with scissors bite. Scissors bite rarely involves anterior and posterior sites concuttently across the dental arch but usually affect single tooth. Even in the single tooth scissors bite cases, more likely to be met in the clinical fields, immediate dental intervention is indicated because continuous occlusal forces that exacerbate the already adverse axis of the posterior teeth. In this case study, patients with single tooth scissors bite, each 7, 14, 12, and 16 years old, were each treated with criss-cross elastic, fixed appliance, removable appliance, and miniscrews. With the proper selection of appliances appropriate to each specific cases, good treatment outcome can be achieved without resulting any side effects. 중심교합위의 상태에서 편측 혹은 양측으로 상악 구치부의 치아가 하악 구치부의 협측으로 위치한 경우를 scissors bite라 고 한다. 이는 상악의 폭경이 크거나 하악의 폭경이 좁은 경우 발생한다. Scissors bite의 경우 방치하게 되면 하악의 성장이 방해받게 되고 그 결과, 악궁 폭경의 부조화가 심해져 저작 장애를 일으킬 수 있으므로 조기 차단 교정이 반드시 필요하다. 실제 임상에서는 여러 치아의 scissors bite보다 최후방 구치 혹은 그 외 하나의 구치만의 single tooth scissors bite(STSB)을 보이는 경우가 많다. 이러한 STSB의 경우도 방치하게 되면 저작력으로 인하여 구치의 각도가 더욱 악화되므로 즉각적인 치료가 필요하다. 본 증례에서는 STSB를 보이는 7세, 14세, 12세, 16세의 환자에게 각각 criss-cross elastic, 고정성 장치, 가철성 장치, miniscrew를 사용하여 치료한 증례를 보고하였다. 각 환자의 증례에 적합한 장치를 잘 선택하여 사용한다면 치아를 정출시키는 등의 부작용을 야기하지 않고 양호한 결과를 얻을 수 있을 것이다

레이저 포화흡수체 Nd:LSB에 관한 연구

지명훈,오세용,이영우 목원대학교 멀티미디어신기술연구소 2001 멀티미디어신기술연구소논문집 Vol.1 No.1

본 논문에서는 다른 Q-스위칭용 포화흡수체보다 넓은 천이 영역을 가지고 있는 포화흡수체 Nd:LSB가 Q-스위칭 소자로서 가능한지 보였으며, 최적화된 출력 거울의 반사율, 최대 출력, 출력 에너지, 펄스폭, 출력 효율을 수치적으로 분석하였다. 그 결과 Nd:LSB를 이용한 1319nm 파장의 수동형 Q-스위칭 Nd:YAG 레이저의 특성을 예측할 수 있었고, 공진기 거울의 반사율 98%, 공진기 길이 30㎝로 하였을 경우 출력 31.3MW, 펄스폭 6.22ps를 얻을 수 있다. In this study, it's shown that the saturable absorber Nd:LSB which has broad absorption bandwidth than other saturable absorber as Q-switching system has a capability as a saturable absorber in Q-switching system. In this system, we theoretically analyzed the optimized output mirror, peak power, output power, pulse width and output efficiency. As the result, the passively Q-switched 1319nm Nd:YAG laser using Nd:LSB as a saturable absorber gives the optimized output mirror reflectivity 98% and peak power of 31.3MW and pulse width of 6.22ps at 30㎝ resonator length theoretically.

상악 제2유구치와 상악 제1대구치의 치관 형태: 치아계측학적 연구

김지인,현홍근,김영재,김정욱,장기택,이상훈,한세현,김종철 大韓小兒齒科學會 2011 大韓小兒齒科學會誌 Vol.38 No.4

The basic structure of the primary crowns usually resemble their succeeding permanent teeth. However, maxillary second primary molars resemble ipsilateral first permanent molars. Accordingly in this study, odontometric data of the two teeth was obtained, then analyzed to verify the morphological relationship and sex difference between the two teeth. Dental study casts were examined for their mesiodistal and buccolingual width of the crowns, diameter of each cusps, and intercuspal distances. Photographs of the crowns were taken to measure the angles between each cusp tip. The results are as follows : 1. In boys, PrI, PaI, DBC angle, and MBC angle did not show any statistically significant difference between the two teeth(p>0.05), and moderate level of correlations were observed. 2. In girls, crown index, DBC angle, and MBC angle of the two teeth did not show any statistically significant difference(p>0.05), and moderate level of correlations were recognized. 3. Measurements that did not show statistically significant difference between the two teeth in both boys and girls were DBC angle and MBC angle(p>0.05). In DLC angle, however, statistically significant difference was observed(p<0.01). 4. Most of the measurements showed sex differences, except DBC angle, which did not show any sex difference in both teeth(p>0.05). 유치 치관의 기본적인 구조는 대개 계승 영구치를 닮는다. 그러나 제2유구치는 계승 영구치인 제2소구치보다 오히려 제1대 구치와 더 유사한 경향이 있다. 이에 본 연구는 한국인에서 상악 제2유구치와 제1대구치의 치아계측학적 자료(odontometric data)를 얻어 두 치아의 형태와 크기 사이의 연관성을 살펴보고, 나아가 남녀간의 차이점 유무를 고찰해 보고자 하였다. 남아 150명, 여아 150명 총 300명의 모형을 이용하여 상악 제2유구치와 상악 제1대구치의 근원심 치관 폭경, 협설측 치관 폭경, 각 교두의 직경, 교두정간 거리를 계측하였고, 치관의 교합면 사진을 촬영하여 각 교두정 사이의 각도를 측정하여 다음과 같은 결과를 얻었다. 1. 남아에서 Protocone index, Paraconeindex, Distobuccal cusp(DBC)각, Mesiobuccal cusp(MBC)각은 상악 제1대 구치와 제2유구치 사이에 통계적 유의차가 관찰되지 않았고(p>0.05), 중등도의 상관관계가 확인되었다. 2. 여아에서 crown index, Distobuccal cusp(DBC)각, Mesiobuccal cusp(MBC)각은 상악 제1대구치와 제2유구치 사 이에 통계적 유의차가 관찰되지 않았고(p>0.05), 중등도의 상관관계가 확인되었다. 3. 남, 여 모두에서 Distobuccal cusp(DBC)각, Mesiobuccal cusp(MBC)각은 두 치아 사이에 유의할만한 차이를 보이 지 않았고(p>0.05), Distolingual cusp(DLC)각에서는 통계적 유의차가 관찰되었다(p<0.01). 4. 대부분의 계측치에서 남녀 차이를 나타냈지만, Distobuccal cusp (DBC)각은 상악 제1대구치와 제2유구치 모두에서 남녀 차이를 보이지 않았다(p>0.05).

Tuning the Microstructure and Mechanical Properties of Cold Sprayed Equiatomic CoCrFeMnNi High-Entropy Alloy Coating Layer

Ji‑Eun Ahn,Young‑Kyun Kim,Sang‑Hoon Yoon,Kee‑Ahn Lee 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.7

An equiatomic CoCrFeMnNi high entropy alloy (HEA) coating layer was prepared via a cold spray (CS) process. In orderto control the microstructure and nano-indentation properties of the CS HEA, heat treatments were employed. CS HEAcoating layer showed a heterogeneous microstructure where ultra-fine grains were formed at the particle interfaces, whilecoarse grains were formed inside the particles. Furthermore, deformation twins (DTs) were also formed inside the particlesdue to severe plastic deformation (SPD) in each particle generated during the CS deposition. For the 550 °C heat treatment(HT), fine Cr-rich precipitates were additionally formed at the grain boundary and particle boundary. By contrast, recrystallizationoccurred during 850 °C HT, while the size of the Cr-rich precipitate increased. The nano-indentation hardness ofthe CS HEA coating layer was 10.9 GPa, which was ~ 3 times higher than that of the conventional cast HEA. The superiorhardness of the CS HEA might has been enabled due to the combination of the high dislocation density, DTs, and ultra-finegrains. Based on the results above, the strategy to control the microstructure and mechanical properties through HT of theequiatomic CoCrFeMnNi HEA coating layer prepared via the CS process has been discussed.

색상 측정 기기를 이용한 복합레진 적층 수복과 단일 수복의 색상 비교 분석

송영상,김자현,이빈나,장지현,장훈상,황윤찬,오원만,황인남 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2

Objectives: This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers. Materials and Methods: For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering compositie resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin. Results: Color difference (△E*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at anythickness (△E* > 3.3). Conclusion: When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for chossing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel. (Restor Dent Endod 2012;37(2):84-89)

Water glass로부터 ZSM-5의 합성

우훈희,홍지숙,서정권,이관영,이정민 한국공업화학회 2002 응용화학 Vol.6 No.2

In order to seek optimum conditions for ZSM-5 formation in the absence of organic template,the effects of both starting composition and water glass as silica source were examined. Water glass was most inexpensive among silica sources, but this was difficulty in reactant control because of contained much alkali ingredient, Considering environmental problem and economic performance,chose alkali drawing-out method to use methanol newly to remove alkali ingredient of waterglass. Characterization of ZSM-5 was carried out by means of XRD, SEM.

동계 난방시 구조체 축열 공조시스템의 축·방열 특성에 관한 연구

임지훈,이시환,차영호,정광섭,이정재 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

It is the plan that storage gets energy done by in structure with what thermal storage of structure changes only supply air duct among the existing HVAC system, and a basic principle coordinates the damper that it was installed makeup air in supply air duct like former HVAC system to an inside at supply and a night by day, and do makeup air supply with in ceiling space of thermal storage of structure HVAC system. This thermal storage of structure HVAC system uses the existing utility system, and energy saving can get structure of building done with energy storage, before air conditioning and peak load cut getting day heat load done.