유기질비료 시비량에 따른 오미자 묘목의 초기 생육특성에 관한 연구

이경아,박태호,박성용,김도현,오문국,김민수,안태진,이상원,김영국,안영섭,박충범,차선우,송범헌 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.1

This study was carried out to have basic and applied informations to find the optimum nitrogen fertilization level for organic cultivation and to investigate early growth characteristics of Schizandra chinensis Baillon. Different application levels of the organic fertilizer were based on the recommended rate of N fertilizer. Five different levels of the organic fertilizer were applied to S. chinensis and early growth responses such as the length of vine, the diameter of vine, the number of leaves, and the number of branches were investigated. Lengths of main and total vines were shown longer at the level of 1.0 time organic fertilizer than those at others. The vine length at early growth was the highest at the level of 1.0 time organic fertilizer among the treatments. Stem diameter was shown thicker level of 1.0 time organic fertilizer than others on August and September, whereas on October it was the thickest in the conventional cultivation. Number of leaf was increased higher at the level of 1.0 and 2.0 times organic fertilizer than that in the compared to conventional. The number of branches was appeared the lowest at the level of 1.0 time organic fertilizer at early growth, however they were increased through progressing their growth stages. They were not significantly difference among the treatments except for the level of 2.0 times organic fertilizer. Based on the research results, the growth of S. chinensis was commonly higher at the level of 1.0 time organic fertilizer compared to other treatments.

저밀도 폴리에틸렌의 트리잉진전에 미치는 부분방전펄스의 영향

박노봉,박영국 충주대 산업과학기술연구소 1998 産業科學論文集 Vol.6 No.-

Inception and ptopagation of electrical tree and properties of partial discharge(PD) pulses accompanying with tree in low density polythylene were discussed. We observed the characteristic of process of electrical tree by using optical microscope and investigated the statisical characteristics of the PD pulses by analyzing PD quantities and distribution pattern. The PD quantities detected and analyzed were PD magnitude, repetion rate, average discharge power, mean phase angle and q-n, Φ-n Φ-q and Φ-q-n distribution pattern. The statistical operators used were skewness(s), kurtosis(k) and average phase angle. The average discharge power of PD appears good linear relation with propagation of tree and the repetition rate and magnitude of PD are increased with the propagation of tree. The skewness and average discharge phase angle of PD pulses increases as the Propagation of ree. The kurtosis was about 1.8 at the Inception of tree, but It increased as the propagation of tree.

급성 신부전증을 초래한 Wegener씨 육아종증 1례

박일,임영국,최성도,임현성,정종훈,문철웅 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

호흡기 증상과 급성신부전증이 발생된 환자에서 혈액검사, 혈청학적 검사, 방사선학적 검사, ANCA test 및 신생검을 통하여 Wegener씨 육아종증을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. 본질환이 재발하는 경우는 cyclophosphamide에서 azathioprine으로 치료약을 바꾸었을때나 특히 ANCA 반응이 양성으로 지속시 발생한다. Godman과 Churg는 상기도의 괴사성 육아성 병변, 하기도의 괴사성 혈관염, 국한성 신사구체염을 진단의 지표로 삼았다. 특히 상기도 점막의 생검 소견상 괴사성 육아성 혈관염이 보이면 일단 본 증을 의심하고 폐 생검과 신 생검이 필요로 한다. Wegener's Granulomatosis is an uncommon disease which is characterized by granulomatous vasculitis of both lung and kidney. Although the cause is unknown, it's suggesting that disordered immunity with both antibody and cell-mediated tissue damage occurs. The disease affects patients of any age. Characteristic clinical manifestations are diverse but in clude saddle nose deformity, sinusitis, productive coughing, myalgia, fever etc. Characteristic laboratory abnormalities include elevated ESR, neutrophilic leukocytosis, anemia and positive test for ANCA test. Renal biopsy is important for diagnosis. The treatment of choice is a combination of corticosteroid and cytotoxic agent. A53-year-old woman was admitted to our hospital because of productive coughing, short of breathing, oliguria, nausea, and vomiting. Three months ago, she was suffered from general weakness, poor appetite, tingling sensation on extremity, and loosely stool. Twenty days ago, above symptoms were aggravated, she admitted local clinic. Six days ago, because of CBC showed anemia , she was done transfusion. During transfusion, she was developed urticaha then productive coughing, dyspnea, increased serum BUN and creatinine levels. She was transferred to our hospital under the impression of ARF. On the admission, she was chronic ill-looking appearance with pale conjunctiva, tachypnea, dyspnea, and cold sweating. We have checked the patient by CBC, serum and serologic test, X-ray, ANCA test, renal biopsy. With renal biopsy microscopic examination study revealed necrotizing vasculitis, We treated a combination therapy with methyl-PDS and cyclophosphamide. She had a good response. So we report wegener's granulomatosis with the review of relevant literature.

Ⅲ급 부정교합자의 양악 수술과 하악 편악 수술 시 연조직 변화에 관한 비교 연구

박영국,장인희,이영준 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.1

악교정 수술 시행 시 연조직 변화에 대한 대부분의 연구는 Ⅱ급 부정교합을 대상으로 하였다. 또한 수술 방법에 따른 연조직 변화에 대한 비교 연구가 부족하였다. 따라서 이 연구는 골격성 Ⅲ급 부정교합자에서 상악골 전진술과 하악골 후퇴술을 동시에 시행한 양악 수술과 하악골 편악 수술 시행 시, 경조직과 연조직 측모 및 연조직 두께의 변화를 관찰하고, 수술 전후 변화의 상관성을 산출하며, 경조직 변화에 수반하는 연조직 변화의 비율을 산출하여 교정-악교정 수술 복합 치료 계획 수립과 결과의 예측에 이용하고자 시행되었다. 경희대학교 치과병원 교정과에 내원하여 골격성 Ⅲ급 부정교합자로 진단받은 환자 52명을 대상으로 하여, Le Fort I osteotomy를 이용한 상악골 전방이동술과 시상분할골절단술을 이용한 하악골 후퇴술을 시행한 양악 수술군 26명과 하악골 후퇴술만을 시행한 편악 수술군 26명으로 구분하여, 수술 전후 측모두부방사선규격사진을 계측, 분석하여 다음과 같은 결과를 얻었다. 양악 수술군은 골격 변화량의 72.4% 비율로 상순 부위 연조직의 전방 이동을 보였으며, 편악 수술군은 통계적으로 유의한 변화를 보이지 않았다. 비순각은 양악 수술군에서 편약 수술군에 비해 더 크게 증가하였다. 이순각은 편악수술군에서 더 크게 감소하였다. 하악골의 후방 이동에 따른 연조직 pogonion의 후방 이동은 양악 수술군에서 98%, 편악 수술군에서 109%로 편악 수술군에서 더 크게 나타났다. 양악 수술군에서는 편악 수술군에 비하여 경조직의 변화에 수반하는 상순에서의 큰 변화가 나타났다. 편악 수술군에서는 상순의 변화는 미약하엿으며, 하순 및 이부의 변화가 양악 수술군에 비해 두드러지게 나타났다. Numbers of postulations lie on the difference of integumental changes with two major surgical remedies of one jaw vs. two jaw surgery in skeletal Class Ⅲ malocclusion. Accordingly it was the aim of the study to elucidate the skeletal profile changes with an accompanying disposition of soft tissues, consequently to yield the correlation and ratio of soft tissue changes with two types of surgical procedures, which in turn make it possible to predict the soft tissue outcomes by means of assembled regression equations. Cephalometric headfilms of fifry two adult skeletal Class Ⅲ comprised of 26 maxillary advancement by Le Fort I osteotomy and mandibular setback by sagittal split ramus osteotomy simultaneously (double jaw surgery, group A), 26 mandibular setback alone (one jaw surgery, group B) were statistically analyzed. Group A manifested 72.4% soft tissue advancement to skeletal changes in the upper lip area, while group B appeared to have no statistically significant changes. The nasolabial angle showed more increment in group A than in group B, whereas the mentolabial angle illustrated more reduction in group B. The backward movement of soft tissue pogonion to skeletal change revealed 98% in group A, and 109% in group B. The double jaw surgery group characteristically revealed remarkable integ umental change in the upper lip area, while the one jaw surgery had major effects in the lower lip and soft tissue pogonion areas.

한국산 긴몰개(Squalidus gracilis majime, Cyprinidae)의 난발생

박경서,홍영표,문운기,최신석,안광국 한국육수학회 2005 생태와 환경 Vol.38 No.1

한국산 긴몰개 (Squalidus gracilis majimae)의 난발생 과정을 연구하기 위하여, 긴몰개의 친어와 생태적 조사는 충청남도 보령시에 위치한 보령댐과 웅천천에서 실시하였다. 자연 산란에 의해 수정된 난과 배 발생의 형태학적 설명은 다음과 같이 요약된다. 수정란의 형태는 둥글고, 점착성이 있으며 투명하였고, 수정란의 평균직경은 2.9±0.3 ㎜ (n = 30)였고, 유구가 존재하지 않았으며, 수정란의 발생은 수온 26±1.5℃에서 관찰되었다. 수정 후 20분에 배반이 형성되었으며,48분 뒤 2세포로 나뉘어졌고, 포배기는 수정 후 5시간 40분에 나타났으며, 낭배기는 수정 후 6시간 55분에 관찰되었다. 배체의 형성은 수정 후 12시간 58분부터 시작되었고, 안포와 9개의 체절이 수정 후 17시간 05분에 발견되었다. 수정 후 23시간 30분에 이포가 생겼으며, 25~26개의 체절과 함께 안포안의 렌즈가 수정 후 32시간 35분에 발견되었다. 수정 후 37시간 27분에 뇌의 분화와 함께 배체가 꿈틀거리기 시작했으며, 심장박동과 안포내의 흑색소포가 수정 후 44시간 46분에 발견되었다. 수정 후 50시간 36분 가슴지느러미의 형성과 함께 몸 부분의 흑색소포가 형성되는 것을 끝으로하여 수정 후 57시간 49분에 수정란은 부화되었다. 이때 갓 부화된 자어는 전장이 3.3±0.2 ㎜(n= 120)이었다. 본 연구 결과는 최근 수질오염 및 종 다양성 감소가 시급한 상황에서 종 및 개체군 보존에 기여할 것으로 사료된다. This study was conducted, based on the field survey and laboratory observations, to elucidate egg developmental processes and their characteristics of the Korean slender gudgeon, Squalidus gracilis majimae. For the experiments, the mature adults were collected at the Woongcheon-Cheon Stream and Boreung Reservoir located in Boreung City, Chungnam Province and eggs were obtained from the natural spawning area. Morphological characteristics of the egg and embryonic development were su㎜arized as follows: The shape of the fertilized egg was spherical, adhesive and transparent. The fertilized egg was 2.9±0.3 ㎜ (n = 30) in mean diameter under water temperature of 26 ± 1.5℃, light white in color and had no oil droplets. After 20 minutes from the time of fertilization, a blastodisc was formed and divided into two cells at 48 minutes after fertilization. The blastular stage occurred at 5 hours 40 minutes after fertilization and the gastrular stage was detected at 8 hours 41 minutes after fertilization. The beginning of embryo formation was observed at 12 hours 58 minutes after fertilization and optic vesicles and 9 somites were discovered at 17 hours 05 minutes after fertilization. Differentiation of brains and embryo wiggling were observed at 37 hours 27 minutes after fertilization. Heart beating and the formation of melanophores in optic vesicles were detected at 44 hours 46 minutes after fertilization. The formation of pectoral fins and melanophores in the body were discovered at 50 hours 36 minutes after fertilization. Hatching occurred at 57 hours 49 minutes after fertilization. The newly hatched larvae were 3.3 ±0.2 ㎜ (n = 120) in total length. We believe that these results may contribute the species and population conservations under the situation of accelerated water pollution and the decreases of its diversity.

현역 군인 발생을 중심으로 본 2000년도 국내 삼일열 말라리아 발생 현황

박재원,김영아,염준섭,유정식,양병국,채종일 대한감염학회 2001 감염 Vol.33 No.4

Background : Since 1997, the annual case occurrence of vivax malaria in the Republic of Korea have exceeded 1,000 cases since 1997. The military is thought to be an important source of the current outbreak. We collected various informations about malaria cases (soldiers, veterans and civilians) which occurred in 2000, and analyzed the characteristics of the current outbreak. Methods : Informations about malaria cases of soldiers, veterans and civilians, including name, age, sex, day of onset, region, etc., were collected through the National Institute of Health. Results : Out of total 4,141 cases, 1,288 (31.1%) occurred in the military, 1,273 (30.7%) occurred among the veterans, and 1,580 (38.2%) occurred among civilians. The monthly case occurrence reached its peak in early August. Areas such as Cheolwon, Yeoncheon and Paju showed the highest prevalence. Conclusion : It is considered that the current malaria outbreak has escaped from the exponential growth phase, however, more attention should be paid to prevent further spreading of malaria infection. (Korean J Infect Dis 33:280∼284, 2001)

정상교합자의 Ⅲ급 부정교합자의 저작근 근전도에 관한 연구

박영국,이기수,주보훈 대한치과교정학회 1991 대한치과교정학회지 Vol.21 No.1

The purpose of the present study was to investigate the differences of EMG activity of the masticatory muscles between normal occlusion and Class Ⅲ malocclusion during various jaw functions. 46 subjects of 18.4-25.7 years were employed in this study: 26 subjects were normal occlusions, and 20 subjects were Class Ⅲ malocclusions. The EMG data from the anterior and posterior temporal, anterior and posterior masseter muscles in both sides as mandibular elevators and supra-hyoid muscle group(close to the anterior belly of digastric muscle in right side) as mandibular depressor were recorded with the Medelec MS 25 electromyographic machine. The EMG recordings were analyzed during mandibular rest position, maximal biting, mastication with chewing gum, and swallowing of peanuts. All data were recorded and statistically processed. 1.The maximal mean amplitude of the anterior temporal muscle was stronger significantly in Class Ⅲ malocclusion than in normal occlusion, and then the posterior temporal was weaker during mandibular rest position. 2.The maximal mean amplitudes in the anterior and posterior temporal muscles and the anterior masseter muscle of Class Ⅲ malocclusion was weaker significantly than that of normal occlusion during maximal biting. 3.During mastication of the chewing gum, the maximal mean amplitudes of Class Ⅲ malocclusion was weaker significantly than normal occlusion in the anterior and posterior temporal muscles of the working side, and the duration of Class Ⅲ malocclusion was longer in the anterior temporal muscles of both sides and the posterior temporal and the anterior masseter muscle of the balancing side. There were significant increasings of the latency in balancing anterior temporal, working posterior temporal muscles and supra-hyoid muscle group of Class Ⅲ malocclusion. The silent period durations was 16.36 ms in Class Ⅲ malocclusion while 10.76 ms in normal occlusion, which was statistically different(P<0.05). 4.At swallowing of peanuts, the maximal mean amplitude of Class malocclusion was weaker significantly in the posterior temporal muscle than that of normal occlusion. There was no significant difference of duration between normal occlusion and Class Ⅲ malocclusion. 5.The muscle activities of Class Ⅲ malocclusion had a tendency of decrease less than normal occlusion. And then the muscle activities of the anterior temporal and anterior masseter muscles in Class Ⅲ malocclusion showed the tendency of the increase more than other muscles of Class Ⅲ malocclusion.

초소형 전기 장치에 의한 전기 자극이 치아 이동과 주위 조직 개조에 미치는 효과에 관한 연구

박순정,이영준,박영국,Davidovitch, Zeev 대한치과교정학회 2003 대한치과교정학회지 Vol.33 No.4

낮은 강도의 전류는 골세포의 활성화 대사를 증가시키는 것으로 알려져 왔다. 이 연구는 초소형 전기 장치에 의한 전기 자극이 교정적 치아 이동에 미치는 영향을 규명하기 위하여, 체중 3kg 내외의 고양이 6마리를 대상으로 가철성 교정 장치와 NiTi coil spring(75gm)을 사용하여 상악 견치를 이동시켰다. 실험군측 견치에는 교정력과 간헐적인 20㎂의 전기 자극을 가하였고, 대조군측에는 같은 크기의 교정력만을 가한 후 4주 동안의 치아 이동량을 측정하여 비교하였으며, 치아를 중심으로 조직을 절취하여 탈회하고 조직 처리 후 광학 현미경으로 치주조직의 변화를 비교하여 다음과 같은 결론을 얻었다. 1. 28일간의 실험 기간 동안 실험측의 치아 이동량은 대조군에 비하여 현저히 증가하여, 4주후에 실험측의 치아는 대조군에 비하여 37% 증가된 이동량을 기록하였다. 2. 전기 자극을 받은 치아의 치근 견인측에서 대조군에 비하여 조직학적으로 증가된 골형성 양상이 관찰되었다. 3. 28일간의 전기 자극과 교정력으로 실험측 치아의 압박측에서 대조군에 비하여 증가된 골 흡수 양상이 관찰되었다. 4. 실험군 견치 치근 주위 조직에서는 전반적으로 더 많은 수의 조골 및 파골 세포들과 모세 혈관, 골양 조직들이 관찰됨으로써 증가된 조직 세포 활성을 반영하였다. 5. 1일 5시간 동안의 간헐적 전류 자극은 치아 이동량을 증가 시키고 조직 개조를 활성화 시키는 효과가 있었다. 이상의 결과는 외부에서 가한 낮은 강도의 간헐적 전기 자극으로 교정적 치아 이동량이 많아지고 치주 조직의 개조활성이 증가됨을 보이므로 초소형 전기 장치에 의한 자극은 치아 이동과 주위 조직 개조를 촉진시킬 가능성이 있을 것으로 평가 되었다. Electric current is a highly probable way as a clinical tool for tooth movement. The purposes of this study were to determine the usefulness of exogenous electric currents in accelerating orthodontic tooth movement and to investigate the effects of electric-orthodontic treatment on the remodeling of the periodontal tissue histologically. The study was performed with six male cats weighing around 3kg. The electric device which is providing the direct electric current of 20㎂ was inserted to the removable appliance. The right and left maxillary canines were assigned as control and experimental sides respectively. The control canine was provided with orthodontic force (75gm) only and the experimental side was given the same amount of force and electricity. The lingual buttons were bonded to the maxillary canines and both sides of canines were retracted with NiTi coil spring. The electric device was adjusted to provide 20㎂ direct current to the experimental canines 5 hours a day. The amount of the canine movement was measured with electronic caliper every week. After4 weeks of tooth movement, the animals were sacrificed and the histologic study was performed. The results of this study were as follows : 1. The application of a direct current to the experimental tooth significantly increased the final amount of orthodontic tooth movement. The amount of tooth movement after 28-day was 37% more in the experimental side. 2. The electrically stimulated tooth showed histologic evidence of significant increases in the amount of bones and matrix deposition in the area of tension. 3. In the compression side, the electric-orthodontic treatment stimulated bone resorption more extensively in the experimental canines. 4. After 28 days of electricity exposure and orthodontic force, the experimental side demonstrated significantly more osteoblasts, osteoclasts, capillaries and osteoid tissues, reflecting an increase in the local tissue's cellular activity. 5. Intermittent electrical stimulation (five hours a day) had effects to enhance orthodontic tooth movement and tissue remodeling. These results suggested that the low-intensity exogenous electric current by the miniature electric device might accelerate orthodontic tooth movement and bone remodeling in vivo and have the possibility to reduce the orthodontic treatment duration.

개방교합자의 설근과 구륜근 활성도에 관한 연구

박영국,이기수,최연석 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.2

The purpose of the present study was to investigate the difference of muscular activities of the tongue and lip muscles between anterior open-bite and normal occlusion during various function. Thirty eight subjects of 12.1-39.6 years were employed in this study : Eighteen subjects were anterior open-bites and tweenty subjects were normal occlusions. During rest position, maximum effort of lip sealing, command swallow of saliva and sucking & swallowing of juice, the electromyographic datas of the genioglossus, superior longitudinal muscle of tongue, upper and lower orbicularis oris were recorded and integrated with Medelec MS25 electromyographic machine. Lateral cephalometric radiographs were taken on all subjects for the analysis of tongue posture and size. All data were recored and statistically processed. The findings of this study can be summerized as follows: 1. During the rest position, muscular activity of tongue was higher than that of lip muscle in open-bite, but no difference in normal occlusion group. 2. During the swallowing of juice, the activity of orbicularis oris was higher than that of genioglossus in open-bite. But the normal occusion was showed higher activity of tongue during the swallowing of juice. 3. The open-bite, compared to the normal occlusion. had higher value of tongue muscle activity during the rest position. 4. Compared to normal occlusion group, the open-bite had higher value of lip muscle activity during the sucking and swallowing of juice. 5. during the command swallow of saliva, the normal occlusion was showed harmonious swallowing pattern, but the open-bite showed much variation and disharmony in muscular contraction sequence, tended to absent of muscle activity. 6. At the lateral cephalometric radiographs, compared to the normal occlusion, the open-bite was showed lower tongue posture, But no difference was found in intermaxillary space. It is suggested that the open-bite, compared to the normal occlusion, had higher muscular activity of tongue during the rest position and various functions, showed lower tongue posture on the lateral cephalogram. In the development of anterior open-bite malocclusion, these factors may be an etiologic factor.

Effect of Dietary Monascus Pigment on the Liver Damage Induced with CCI₄in Rats

윤종국,--,--,--,-- THE KOREAN SOCIETY FOR BIOMEDICAL LABORATORY SCIEN 2003 Journal of biomedical laboratory sciences Vol.9 No.3

In the biological world, there are a number of ecological fights for survival between each organism such as plants, animals and microorganism. In such events, an organism can use its natural bioactive products as defence agent against other organism. Furthermore, natural bioactive products can be utilized for medicine or functional food. Recently, we investigate the effect of Monascus pigment extracted from a fungus, Monascus anke, on the alcohol metabolism and blood lipid profile. In the present study, it is observed that Monascus pigment supplemented dietary may have a hepatoprotective effect on rat's liver damage induced with CCl₄. By treatment with CCl₄(3 times, I.P), liver damage was reduced more in the rats fed 2% Monascus pigment extract supplemented diet than those fed standard diet, based on the serum levels of alanine aminotransferase, microsomal glucose-6-phosphatse activity and hepaic malondialdehyde content. On the other hand, oxygen free radical generating enzymes, hepatic P-450 dependent aniline hydroxylase, xanthine oxidase, and oxygen free radical scavenging enzymes, hepatic glutathione S-transferase, catalase, superoxide dismutase activities were generally higher both in CCl₄, treated group and control fed 2% Monascus pigment extract supplemented diet than those fed standard diet. In conclusion, the rats fed 2% Monascus pigment extract supplemented diet showed more reduced liver damage than those fed standard diet, which may be due to the acceleration of oxygen free radical metabolism.