남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

Helicobacter pylori와 대장균의 Shuttle Vector 개발

조명제,이우곤,이상룡,김경희,안영숙,김성희,김현주,류복덕,최여정,윤영혜,백승철,전영석,이광호 경상대학교 유전공학연구소 1997 遺傳工學硏究所報 Vol.16 No.-

In this study, a vehicle vector using cryptic plasmids was constructed for gene transfer in Helicobacter pylori. pHP51(3.9 kb) and pHP489(1.2 kb) were selected for constructing vectors from cryptic plasmid of H. pylori isolates in Korea. The HindⅢ-digestedDNA fragment(1.2kb) of pHP489 and 1.6kb DNA fragment of pHP51 were ligated with a kanamycin resistance gene(aph3'-Ⅲ) from C. jejuni to produce the recombinant plasmids pHP489K and pHP51K, respectively. Transformation frequency of pHP51K by electroporation was low. But pHP489K could be effectively transformed into various H. pylori strains. In order to design an intermdiate vehicle vector for gene transfer into H. pylori, pBlueHP489K was prepared by recloning pHP489K DNA into pBluescript and pTZ19R vector. This vector permitted the DNA fragment containing pHP489 sequence, aph3'-Ⅲ, and cloned DNA to be cut and self-ligated in the SacⅠ site after cloning. ureA and ureB gene were inserted into pBlueHP489K, resulting in pBlueHP489K/AB. The DNA fragment containing pHP489, kanamycin resistance gene(aph3'-Ⅲ), and urease structural gene was cut away from pBlueHP489K/AB and self-ligated to generate pBlueHP489K/AB. pBlueHP489K/AB made urease-negative H. pylori strains restore their urease activity. By this experiment, pBlueHP489K was confirmed to be the vehicle system for transferring H. pylori genes.

재발성 정동장애의 장기 경과

전영철,이정태,김광수 한국의학사 1993 診斷과治療 Vol.13 No.5

개방교합성 골격 형태를 가진 아동과 성인의 치성보상 양상

전영미,박동철,김정기 대한치과교정학회 1999 대한치과교정학회지 Vol.29 No.2

심한 골격성 부조화를 보이는 환자에서 치열 보상에 의하여 교합 접촉이 양호하게 유지되는 경우를 자주 볼수 있으며, 이러한 치열 보상은 삼차원 평면 모두에서 발생한다. 본 연구에서는 개방교합성 골격형태의 치열 보상 양상을 관찰하고, 이러한 골격형태를 보이는 성인과 아동의 치열보상 양상의 차이를 비교하고자 하였다. 개방교합성 골격형태를 보이는 환자60명과 정상군 60명을 대상으로 하였으며 이들 각각을 연령에 따라 8-12세의 아동군과 17세 이상의 성인군으로 분류하여 다음과 같은 결론을 얻었다. 1. 개교성골격군의 후하안면고경은 아동과 성인 모두에서 정상군보다 적으며(p<0.01), 전하안면고경은 아동에서 정상군과 차이가 없으나 성인에서는 정상군보다 크다(p<0.01). 2. 개교성골격군에서 기저골 길이에 대한 상하악 전치의 맹출비는 아동기에 정상군보다 크며(p<0.05), 성인기의 상악전치의 맹출비는 아동기에 비해 컸으나(p<0.05) 하악 전치의 맹출비는 아동기와 유사하였다. 3. 개교성골격군에서 상·하악 구치의 기저골의 길이에 대한 상대적인 맹출량은 아동기에 정상군과 차이가 없었지만, 성인에서 상악 구치의 상대적인 맹출량은 정상군보다 컸으며(p<0.01), 하악 구치의 상대적인 맹출량은 정상군과 동일하였다. 4. 개교성골격군에서 하악평면에 대한 하악 교합평면의 경사는 아동이나 성인 모두에서 정상군보다 더 큰 각을 이루며 (p<0.01), 상악 교합평면 경사는 성인기에 아동기보다 컸다(p<0.05). 상악 교합평면은 성인기에 아동기보다 전상방경사를 보였다.(p<0.01). 5. 개교성골격군에서의 치성보상은 아동기에 이미 상 · 하악 전치부의 과맹출에 의하여 이루어진다. 개교성골격군은 성장과정중 상악 구치부의 과도한 수직적 발육을 보이며 이에 대한 보상적 반응으로 상 · 하악 전치부는 정상군보다 더 큰 맹출량을 보이는데 특히 상악 전치부에서 더 큰 맹출비를 보인다. Although there is a severe underlying skeletal deformity,the dentition has often maintianed some occlusal contact and interdigitation by the teeth compensating in their positions for the skeletal problem, and these dental compensations are manifested in all three planes of space. The purpose of present investigation were 1) to study the pattern of dentoalveolar compensation of hyperdivergent skeletal pattern : and 2) to compare the dentoalveolar compensations of hyperdivergent skeletal pattern in children with adults. The samples selected for this study were consisted of 60 subjects in normal group, 60 subjects in hyperdivergent group. Each was divided into two subgroups by age ; child groups(8~12yr old) and adult groups (17yr old over). The findings of this study were as follows; 1. In child, hyperdivergent subjects had smaller posterior lower facial height(p<0.01) and slightly longer anterior lower facial height than normal ones. In adults, they still expressed smaller posterior lower facial height and much longer anterior lower facial height than normal ones(p<0.01). 2. Hyperdivergent subjects had larger amount of upper and lower incisor relative eruption to their basal bone length than normal ones(p<0.05). In adult, relative eruption of upper incisor was increasing(p<0.05), although relative eruption of lower incisor remained the same as the child. 3. In child,there was no difference between hyperdivergent group and normal one in the upper and lower molar relative eruption to their basal bone length. In adult, hyperdivergent group had larger amount of upper molar relative eruption than normal ones(p<0.01), but relative eruption of lower molar was similar to normal ones. 4. Hyperdivergent group had larger angle between lower occlusal plane and mandibular plane than normal group(p<0.01). Upper occlusal plane of adult groups rotated more antero-superiorly than child groups, and adult hyperdivergent group had steeper upper occlusal plane than normal group(p<0.05).

EMR 남중생의 심폐기능에 관한 연구

전동호,노영태,이상봉,이영덕,박병주,박철준 釜山大學校 附設 體育科學硏究所 1997 體育科學硏究所 論文集 Vol.13 No.-

The purpose of this study is to offer proper physical programs to the middle school EMR boys and to improve their cardiorespiratory function through measuring cardiorespiratory function when they are rest situation, all out situation ten EMR boys, divided into two groups as five exercise boys and five non- exercise ones, played soccer game more than one hour a week for 10 weeks. The results of the measurement by treadmill were as fallows 1. In analyzing the two group t-test score it was found that HR and RQ of both group didn't show statistically significant difference of all(p<0.05). 2. VE, VO₂, Vt, O₂,pluse, CO₂,were revealed the significant difference of rest situation with the exception of all-out situation and recovery(p<0.05) 3. VE, VE/VO₂, O₂/ml/kg. O₂/kg/HR, were revealed the significant difference of all-rest situation with the exception of rest situation and recovery(p<0.05) 4. VO₂, Vt, O₂pluse were revealed the significant difference of recovery situation with the exception of all-out situation and rest(p<0.05) 5. The non-exercise group higher figure in HR, Vt, O₂/ml/kg than exercise group except in VE in the rate of recovery situation in 3 minute

von Willebrand's diseasee 1예

박치영,모성환,문철호,곽재정,김태종,전용준,박유환,정춘해 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

von Willebrand's disease 1예

박치영,모성환,문철호,곽재정,김태종,전용준,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1995 The Medical Journal of Chosun University Vol.20 No.2

von Willebrand's disease (vWD) is the most common autosomal-dominant inherited disorder resulting from a quantitative or a qualitative defect of von Willebrand factor (vWF). The most diagnostic pattern is the combination of a prolonged bleeding time, a reduction in plasma vWF concentration, a parallel reduction in ristocetin cofactor activity, and reduced factor Ⅷ activity, In this case, ristocetin-induced platelet aggregation data were compatible with that of vWD. Bleeding times were prolonged over 4 minutes, vWF antigen levels were 45%. vWF ristocetin cofactor activities were 0~1% and factor Ⅷ levels were 31%, when compared to the normal control. We report the case of a family with vWD. characterized by a quantitative defect in vWF

尿素溶液에서의 二酸化黃의 吸收

韓英鎬,全英哲 釜山水産大學校 1984 釜山水産大學 硏究報告 Vol.24 No.2

SO₂가스를 吸收除去하는 濕式脫黃法에서 尿素를 吸收劑로 사용하였을 때 吸收劑의 濃度와 溫度에 따른 吸收能力, 吸收된 氣體 중의 SO₂의 分壓 및 吸收液 중의 SO₂의 濃度, CO₂가스의 影響등을 實驗한 結果를 要約하면 다음과 같다. 1. 吸收液으로서 蒸溜水 100 mol에 尿素 0.1 mol을 溶解시킨 것을 사용하여 SO₂가스 (3.530ppm)를 吸收시킨 結果 尿素(一酸鹽基) 1.0mol에 대하여 溫度 30℃에서는 吸收되는 SO₂量이 0.48mol 이어서 理論當量(0.5mol)과 거의 같고, 50℃에서는 0.44mol, 70℃에서는 0.35mol, 80℃에서는 0.26mol로서 理論當量의 1/2정도였다. 2. 吸收液으로서 各各 0.9mol, 1.0mol, 1.1mol, 1.2mol의 尿素를 蒸溜水 100mol에 溶解시킨 것을 사용하여 SO₂를 吸收시킨 結果 各 一定 農度 吸收液의 0.1mol씩 減少함에 따라 SO₂의 減少量은 같다. 3. 吸收液으로서 蒸溜水 100mol에 尿素 1.0mol을 용해시킨 것을 사용하여 SO₂와 CO₂를 함께 吸收시킨 結果 CO₂의 影響은 없었다. The study was carried out to investigate SO₂gas absorbing capacity using urea solution as absorbent at different conditions such as temperature and various conditions of absorbent. The effects of CO₂gas for absorbing capacity were also examined. The following results could be summarized: 1. When SO₂gas, of which initial condition was 3,530 ppm, was absorbed in absorbing solution made by dissolving 1.0 mole urea in 100 moles distilled water, at the temperature of 30, 50, 70 and 80℃, the amounts of the absorbed SO₂gas per 1.0 mole of urea were 0.48 mole at 30℃, 0.44 mole at 50℃, 0.35 mole at 70℃ and 0.26 mole at 80℃ respectively. The quantity of absorbed SO₂gas at 30℃ were nearly approached to the theocratical equivalent of 0.5 mole, while other was about half of the equivalent at 80℃. 2. The reduced quantity of the absorbed SO₂gas due to the reduction of urea concentration at every 0.1 mole unit seemed to be constant at a given temperature. 3. The result that SO₂and CO₂were absorbed to the absorbent which 1.0 mole urea were dissolved in 100 moles distilled water was that the influence of CO₂gas had no significance.

회맹장 및 대장을 침범한 장 결핵에 있어서 바륨을 이용한 방사선 이중조영촬영 소견에 대한 연구

진용현,전혜정,이용근,강철호,조성범,김윤환,박철민,차상훈,김일영,이혜경 건국대학교 의과학연구소 2002 건국의과학학술지 Vol.12 No.-

To determine the characteristic double contrast barium enema findings of ileo-cecal and colonic tuberculosis and to make differential diagnosis from other bowel inflammatory disease. Sixty-seven patients confirmed as ileo-cecal and/or colonic-tuberculosis in six hospitals were evaluated retrospectively. The diagnosis was proven by endoscopic biopsy, surgery, and clinical follow up. Nine of 67 patients were excluded because radiologic findings were normal though endocopic biopsy examinations resulted in tuberculosis. Histopathological diagnosis were madein 58 cases as follows: endoscopic biopsy(n=29), operation(n=12), follow up examination(n=14), tissue culture(n=1), laparoscopic biopsy(n=2). There were 30 men and 28 females. The mean age were 36 yrs(range:16-67), 34 patients were in the second and third decade. The distribution of lesions, morphological characteristics, mucosal changes, ulcer shape and depth, associated with other tuberculous lesion, multiplicity were retrospectively analyzed in the findngs of double contrast barim enema. The commonest clinical symptoms were abdominal pain(n=35, 60%) and diarrhea(n=18, 31%). The chest radiography revealed association of pulmonary tuberculosis in 39 cases. Tuberculous lesions of other organs except chest were present in five cases. Double contrast barium enema findings showed a thickening and irregularity of intestinal mucosal fold(n=29, 50%), bowel contraction and/or shortening(n=26, 45%). There were small, nodular, superficial ulcers in the case of ulcer depth less than 2 mm in the depth. As many as 39 cases(67%) in this series had two or more lesions in the intestinal tuberculosis. The involved segment revealed symmetrical feature(n=21, 36%). Inflammatory pseudopolypoid lesions were noted in 30 cases(52%). The ileo-cecal region was involved in 38 cases(66%). The ascending colon(n=25, 43%) was the second commonest site with or without contiguous cecal involvement. Lesions in terminal ileum, ileo-cecal valve, transverse colon, descending colon and appendix were seen in 19, 18, 18, 12 and seven cases, respectively. Among 18 cases of ileo-cecal valve lesions, there were incompetency in nine cases(16%) and wide gapping in four cases(7%). In 14 cases, tuberculous enterocolitis was diagnosed by clinical follow-up and double contrast barium enema study. 12 out of 14 cases, the findings of double contrast barium enema of tuberculous enterocolitis were normalized after anti-tuberculous medication. However, two cases showed more aggravated state than before due to inappropriate treatment. Double contrast barium enema plays an important role in the diagnosis of tuberculous enterocolitis, determines the type, site and extent of the involvement and helps in treatment guide by using sequential studies.

레이저 용융 적층공정을 이용한 정밀 형상 제작

김재도,전병철,권택열,이영곤,신동훈 한국레이저가공학회 2000 한국레이저가공학회지 Vol.3 No.3

For the direct metal shape processing the powder feed device which is different from the widely used in rapid prototyping. Is developed, The three dimensional object is shaped with the melting metal powder. The developed research has applied to rapid prototyping in ultraprecision for MEMS and medical science fields required of rapid manufacture of complex shape. The goal of this study make 3D model which has precision accuracy. Powder spreading apparatus has been more improved because that the control of powder spread is very important in layer manufacturing. It consists of the vibration motor, nozzle and tube which supplies various metal powder. This apparatus could control the spreading velocity that could control powder spreading thickness. Laser on/off switch was adapted because laser scanning velocity must be preserved constantly to prevent heat transformation of laser overheating. The error between sintered thickness and experimental one occurred by shrinkage in sintering melting process. The problem of heat transformation was solved by On/Off switching system.