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Song,Won-Seob,Chi,Hyung-Joon,Rim,Yo-Sup,Yoon,Jae-Ho 한국자원식물학회 2002 Plant Resources Vol.5 No.1
The material of Rhodiola sachatinensis collected from an alpine region of the west-northern China. For analysing the effect, 1 used Rhodiola sachatinensis s rhizome and cultivated callus. In EtOAc, BuOH, H₂0separation the plant showed strong antioxidative activity, but not in Hexane. The radical scavenging effect of EtOAc(RC50, 35(g), BuOH(RC50, 43(g), H₂0(RC50, 50(g) fraction and MeOH extract(RC50, 50(g) of the Rhodiola sachatinensis was comparable to that of synthetic antioxidant BHA(RC50, 14(g) and α-Tocopherol(RC50, 12(g). Total amino acid concentration of plant of In nature condition were 18,009ppm, and major components were arginine, glutamic acid, aspartic acid and valine. The ratio of essential/total amino acid on plant of In nature condition was 46.93%. Total amino acid concentration of callus of In vitro condition were 32,435ppm, and major components were valine, histidine, lysine and leucine. The ratio of essential/total amino acid on callus of In vitro condition was 56.07%. was 56.07%.
Turn-on colorimetric sensing of fluoride ions by a cationic triarylborane bearing benzothiazolium
Song, Ki Cheol,Lee, Kang Mun,Kim, Hyungjun,Lee, Yoon Sup,Lee, Min Hyung,Do, Youngkyu Elsevier 2012 Journal of organometallic chemistry Vol.713 No.-
<P><B>Abstract</B></P><P>A cationic triarylborane Lewis acid bearing benzothiazolium moiety, 2-(4′-dimesitylborylphenyl)-3-methylbenzo[<I>d</I>]thiazol-3-ium ([<B>2</B>]<SUP>+</SUP>) was prepared from a neutral borane (<B>2a</B>) and their crystal structures were determined from X-ray diffraction studies. While <B>2a</B> shows a blue-shift with a small decrease in the UV–vis absorption band upon fluoride binding to the boron atom, [<B>2</B>]<SUP>+</SUP> undergoes a red-shift of the absorption band which tails over visible region, giving rise to the color change of the solution from colorless to yellow. The fluoride binding constant in THF/H<SUB>2</SUB>O (9/1, v/v) is calculated to be 1.3 × 10<SUP>4</SUP> M<SUP>−1</SUP> that is much greater than that of a neutral borane <B>2a</B> (<I>K</I> = 4.2 × 10<SUP>2</SUP> M<SUP>−1</SUP>). DFT calculation results suggest that the absorption process in the fluoroborate (<B>2</B>F) is involved with π(Mes)→π*(phenylbenzothiazolium) intramolecular charge transfer and the greater elevation of the π(Mes) donor level is responsible for the turn-on colorimetric response of [<B>2</B>]<SUP>+</SUP>.</P> <P><B>Graphical abstract</B></P><P>A cationic triarylborane Lewis acid bearing benzothiazolium moiety ([<B>2</B>]<SUP>+</SUP>) was prepared and characterized. [<B>2</B>]<SUP>+</SUP> displays enhanced fluoride ion affinity and turn-on colorimetric response toward fluoride.<ce:figure id='dfig1'></ce:figure></P><P><B>Highlights</B></P><P>► A novel cationic triarylborane Lewis acid was synthesized. ► Fluoride ion affinity was significantly enhanced. ► Fluoride binding led to turn-on color change from colorless to yellow.</P>
갑상선 미세침흡인세포검사 슬라이드에서 BRAF Mutation 검출을 통한 갑상선 유두암의 진단
박원서<SUP>1<,SUP>,이규언<SUP>2<,SUP>,송정윤<SUP>1<,SUP>,정유승<SUP>3<,SUP>,김훈엽<SUP>4<,SUP>,고석환<SUP>1<,SUP>,윤여규<SUP>2,5<,SUP>,Won Seo Park,<SUP>1<,SUP>,Kyu Eun Lee,<SUP>2<,SUP>,Jeong Yoon Song,Ph,D,<SUP>1<,SUP>,Y 대한갑상선-내분비외과학회 2010 The Koreran journal of Endocrine Surgery Vol.10 No.1
Purpose: The prevalence rate of the BRAF mutation in papillary thyroid cancer (PTC) is as high as about 52 to 83% in Korea. Preoperative detection of BRAF mutation on fine needle aspiration cytology (FNAC) slides may help the surgeon make better therapeutic decisions. The present study aims to assess the feasibility of the mutant allele specific amplification (MASA) and restriction fragment length polymorphism (RFLP) method with using conventional FNAC slides and we also wanted to evaluate the clinical role of preoperatively detecting BRAF mutation. Methods: We extracted the genomic DNA from 59 FNAC slides and performed direct sequencing (DS) for detecting BRAF mutation. We could use only 17 slides for the MASA method and 6 slides for the RFLP method due to the shortage of extracted DNA. Additionally, we retrospectively analyzed the cases for which a histological diagnosis could be made. Results: Genomic DNA was extracted from 23 out of the 59 FNAC slides. The BRAF mutation status could be assessed via DS in 33 out of the 59 FNAC slides. The concordance between the MASA method and DS and the RFLP method and DS was 36.3% and 66.7% respectively. The positive and negative predictive value of the 13 indeterminate nodules was 87.5% and 20%, respectively. We could not find any association between the BRAF mutations and the alleged risk factors of PTC. Conclusion: We believe that the purity and the amount of the DNA template must be increased to detect BRAF mutation with using a FNAC slide. Preoperative detection of the BRAF mutation on a FNAC slide may refine the cytological diagnosis, but the application of assessing BRAF mutation as a prognostic marker is debatable. (Korean J Endocrine Surg 2010;10:12-18)
Yoon, Jong Hyun,Roh, Eun Youn,Shin, Sue,Jung, Nam Hee,Song, Eun Young,Lee, Dong Soon,Han, Kyou Sup,Kim, Joung Sung,Kim, Byoung Jae,Jeon, Hye Won,Yoon, Kang Sup Kluwer Academic Publishers 2009 Biotechnology letters Vol.31 No.3
<P>The human umbilical cord (hUC) is a source of adult tissue-derived mesenchymal stem cells (MSCs). A pulsed low-intensity ultrasound (PLIUS) method is described for increasing the yield of MSCs from whole hUC without enzymatic digestion or growth factor supplementation. Analysis of the immunophenotype of cells and a differentiation study were performed to show the compatibility of MSCs. The mean number of cells recovered from primocultures of hUC was 6 x 10(5) cells/cm. PLIUS resulted in a 3.3-fold increase in MSC yield at passage 0. PLIUS exposure increases the yield of hUC-MSCs by promoting release and enhancing proliferation.</P>
송윤섭(Yoon Sup Song) 한국가구학회 2017 한국가구학회지 Vol.28 No.4
Recently, as changes in the office environment, office furniture are changing at a rapid pace. With the development of various smart devices specialized in work type, the concepts of office environment and office furniture are diversified. New furniture design is presented with the new concept of work format and changes to the space, an example of a compact single-person storage space is required.
공예적 융합(Craft Consilience)의 가구디자인 연구 - 자수기법 및 민화를 이용한 가구디자인
송윤섭(Yoon-Sup Song),최기(ki Choi) 한국가구학회 2010 한국가구학회지 Vol.21 No.4
With changing systems of wealth creation around the 21st century, crafts(traditional and industrial crafts) are affected by the trend of changes or lead the trend, that is to say, a turning point of paradigm has come. Values of crafts give the value of users, and the tradition and modern coexists in the trend of times changing from the tradition to the modern so crafts artists’ works are diversified and used in design industries. Based on a place of expression showing various beauty of crafts, identity of design is established through ‘Craft Consilience’ of intangible cultural assets, master craftsman, crafts artists, crafts industries, and crafts departments. As master craftsman and furniture designers meet together to mix master craftsman’s idea with designers’ idea, the new Korean crafts furniture is suggested.
이송희 ( Song-hee Lee ),윤문섭 ( Moon-sup Yoon ),정노희 ( Noh-hee Jeong ) 충북대학교 산업과학기술연구소 2019 산업과학기술연구 논문집 Vol.33 No.1
Surfactant is an amorphous compound that contains both hydrophilic and hydrophobic groups in a molecule. When surfactant comes into contact with water, bubbles are generated. The bubbles produced are useful for commercial use. But, Sometimes it can be disrupted during the synthesis or processing of substances. It's antifoaming agent that removes bubbles. Antifoaming agent is applicated to having a picture developed, dyeing process, making lens and making paper and so on. In this study, Synthesis of Long chain saturated fatty acid methyl esters and Long chain unsaturated fatty acid methyl esters by distillation method and analyzed it by using FT-IR and <sup>1</sup>H-NMR. Surface tension was method and foaming properties were tested on the synthesized antifoaming agents. As a result, Surface Tension was a range of 21.57 to 29 dyne/cm. Antifoaming agent’s properties was range of 0 to 7.8 cm.
송윤섭(Yoon Sup Song) 한국가구학회 2013 한국가구학회지 Vol.24 No.4
The purpose of this study, as well as children who reside in a modern kitchen furniture removal and prevention of risk factors found for the problems at the heart of the residential area in consideration of the safety of the kitchen reflects the importance of the space is to propose a new kitchen furniture design.
전통목가구와 현대소재의 병치(倂置)혼합적 특성을 적용한 가구디자인 연구
송윤섭(Yoon Sup Song) 한국가구학회 2014 한국가구학회지 Vol.25 No.4
The purpose of this research is to provide new direction on the field of the furniture design and to establish the identity of Korean furniture design as the flow of craft’s juxtapose mixture era where it mix and match Korean traditional craft style materials with the modern furniture design. In other words, it is intended to create new furniture design and propose beautiful Korean luxury furniture design based on the precious unique culture with the traditional craft style, juxtaposition of modern furniture, and reinterpretation. It should grant artistic values that can satisfy consumers having various tastes and scarcity values, plus it should put out aesthetic and creative expressions in furniture design putting into the beautiful traditional craft form values. Furthermore, it is required to create new design through values and spirit, materials, techniques, forms, pattern, and usages by interacting, coordinating, and combining tradition and modern East and West, plus craft and design.