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      • 미용사들의 이직욕구에 관한 연구 : 직무스트레스, 근골격계 증상을 중심으로 Focusing on Musculoskeletal Symptoms and Occupational Stress

        서은경,문덕환,박명희,김정원,황용식,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

        Objective : This study was conducted to prepare the fundamental data on desire of job transfer in hairdresser and prevent the health impairment of hairdresser due to occupational stress and musculosketetal symptoms. Methods and Material : The author surveyed the desire of job transfer and muscurlosketetal symptoms and occupational stress with self-reported questionnaire to 105 hairdresser who were working in beautyshop of Busan area and also 121 student in department of cosmestology as control group. Results : The results were as follows: 1. The rates of self reported symptom were 81.0% for shoulder, 72.4% for back, 67.6% for knee, 58.1% for hand in hairdresser, and 79.3% for shoulder, 71.9% for back, 66.9% for neck, 64.5% for hand and knee in student. 2. The rate of musculoskeletal symptom by NIOSH criteria was 36.2% in hairdresser, it was higher than student group(24.8%)(p<0.1). Occupational stress of the groups by occupational stress category was high as decision latitude, skill discretion, psycological job demand, decision authority in order. 3. The results of logistic regression of related varibles with desire of quitting job by logistic regression were statistical bordline significance between desire of quilting and social support(p<0.1). Conclusion : As above results, the author suggest to prepare the preventive program an musculoskeletal symptoms in hairdresser, especially shoulder, and also to control the occupational stress to hairdresser in beauty shop because occupational stress can be a factor of desire of quitting job.

      • 퍼머제의 중금속 농도에 관한 연구

        윤복연,문덕환,박명희,황용식,함성애,손병철,김대환,이창희,김휘동,이채언 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

        Objective : This study was conducted to prepare the fundamental data on heavy metal concentration in hair permanents agents and to prevent the health impairment due to heavy metal. Methods and Material : The author determined of 5 heavy metals(Pb, Cr, Mn, Ni, and Cu) concentration hair permanent agents in the market with flameless atomic absorption spectrophotometer. Results : The results were as follows: 1. The geometic mean concentrations of total subjects were 0.04㎍/g for Pb, 0.09㎍/g for Cr, 0.06㎍/g for Mn, 0.03㎍/g for Ni, and 0.04㎍/g for Cu. 2. The most highest mean concentrations of heavy metals in hair permanent agents by using type were Cr for wave agent and straight cream agent, Cu for setting iron agent, Cr and Cu for coating perm agent. 3. Metal most hlghest mean concentrations of heavy in hair permanent agents by type of color was green for Cu. 4. The mean concentration of Cu among 5 heavy metals in hair permanent agents by marker was most highest. 5. There was most statistically significant difference on mean concentration in hair permanent agents between domestic and foreign products. 6. The exposure amount of heavy metal concentration by one time using the permanent agent were 4.O㎍ for Pb, 9.O㎍ for Cr, 6.0㎍ for Mn, 3.O㎍ for Ni and 4.0㎍ for Cu. Conclusion : As above results author suggest to prepare the preventive program of health impairment due to heavy metal by long term chronic exposure to who were using the hair permanent agents hair designer and customers.

      • SCOPUSKCI등재

        Silica treatment technologies in reverse osmosis for industrial desalination: A review

        Yong-Min Park,Kyung-Min Yeon,Chul-hwi Park 대한환경공학회 2020 Environmental Engineering Research Vol.25 No.6

        Reverse osmosis (RO) is the main process of current industrial desalination, and its performance is affected by the quality of water source. Natural water contains a certain level of silica, which is originated from metal silicate in the earth crust. Due to its complexity, silica fouling is difficult to control, which often causes less efficient design of RO system for safe operation. In the present work, we review the current state of silica treatment technology in RO desalination. Silica chemistry is investigated in standpoint of the scale formation mechanism among multiple forms of silica species and its synergistic interaction with other foulants such as organic matter. Then, pretreatment methods to remove silica in the RO feed water are outlined. They include softening/coagulation, seed precipitation/aggregation, tight ultrafiltration, ion exchange, adsorbents media, and electro coagulation. We finally highlight the mitigation of RO fouling under silica rich conditions, whose concept can be implemented in different ways of antiscalant dosing, high/low pH operation, and intermediate softening of the RO concentrate, respectively. This review will provide comprehensive information and insight about the optimal operation of industrial RO susceptible to silica fouling.

      • Modeling and correction of structural variations in patient-derived iPSCs using CRISPR/Cas9

        Park, Chul-Yong,Sung, Jin Jea,Choi, Sang-Hwi,Lee, Dongjin R,Park, In-Hyun,Kim, Dong-Wook Nature Publishing Group 2016 NATURE PROTOCOLS -ELECTRONIC EDITION- Vol.11 No.11

        <P>Genome engineering technology using engineered nucleases has been rapidly developing, enabling the efficient correction of simple mutations. However, the precise correction of structural variations (SVs) such as large inversions remains limited. Here we describe a detailed procedure for the modeling or correction of large chromosomal rearrangements and short nucleotide repeat expansions using engineered nucleases in human induced pluripotent stem cells (hiPSCs) from a healthy donor and patients with SVs. This protocol includes the delivery of engineered nucleases with no donor template to hiPSCs, and genotyping and derivation/characterization of gene-manipulated hiPSC clones. With engineered nucleases, genomic inversions, reversions, and deletions of short nucleotide expansions can be identified in 2 weeks, and desired clones can be generated in as little as 3-4 weeks. This protocol enables the correction of large inverted segments and short nucleotide repeat expansions in diseases such as hemophilia A, fragile X syndrome, Hunter syndrome, and Friedreich's ataxia.</P>

      • KCI등재

        Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea

        Yong-Hyun Kim,Byung-Joo Park,Hee-Seop Ahn,Sang-Hoon Han,Hyeon-Jeong Go,Dong-Hwi Kim,Joong-Bok Lee,Seung-Yong Park,송창선,이상원,최인수 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.2

        Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an importantreservoir of these genotypes. A survey of 14 pig farms in Korea revealed HEV RNA in 30 of 148 (20.3%) fecal samples. HEV-3a and HEV-4csubtypes were identified in five pig farms (35.7%) and two pig farms (14.3%), respectively. Phylogenetic analysis indicated that the isolatedHEV strains were closely related to previously reported zoonotic strains in Korea. The results of the genetic analysis partially explain thepossible source of the zoonotic transmission of HEV to humans in Korea.

      • SCISCIESCOPUS

        <i>In-Situ</i> Synchrotron X-Ray Scattering Study of Thin Film Growth by Atomic Layer Deposition

        Park, Yong Jun,Lee, Dong Ryeol,Lee, Hyun Hwi,Lee, Han-Bo-Ram,Kim, Hyungjun,Park, Gye-Choon,Rhee, Shi-Woo,Baik, Sunggi American Scientific Publishers 2011 Journal of nanoscience and nanotechnology Vol.11 No.2

        <P>We report an atomic layer deposition chamber for in-situ synchrotron X-ray scattering study of thin film growth. The chamber was designed for combined synchrotron X-ray reflectivity and two-dimensional grazing-incidence X-ray diffraction measurement to do a in-situ monitoring of ALD growth. We demonstrate ruthenium thermal ALD growth for the performance of the chamber. 10, 20, 30, 50, 70, 100, 150 and 250-cycled states are measured by X-ray scattering methods during ALD growth process. Growth rate is calculated from thickness values and the surface roughness of each state is estimated by X-ray reflectivity analysis. The crystal structure of initial growth state is observed by Grazing-incidence X-ray diffraction. These results indicate that in-situ X-ray scattering method is a promising analysis technique to investigate the initial physical morphology of ALD films.</P>

      • Probabilistic evaluation of multi-fluid-phase carbon dioxide storage capacities of saline formations in the Pohang Basin, Korea using three-dimensional geologic modeling and grid-based Monte Carlo simulation

        Park, Jai-Yong,Lee, Sungho,Kihm, Jung-Hwi,Kim, Jun-Mo,Lee, Yong Il Elsevier 2018 International journal of greenhouse gas control Vol.79 No.-

        <P><B>Abstract</B></P> <P>A series of probabilistic evaluation is performed sequentially using three-dimensional geologic modeling and grid-based Monte Carlo simulation as a linked methodology to estimate multi-fluid-phase (i.e., individual gas-, liquid-, supercritical-, and whole fluid-phase) carbon dioxide (CO<SUB>2</SUB>) storage capacities of the target clastic saline formations in the Pohang Basin, Korea. The Pohang Basin is subdivided into the six geologic formations including the two clastic saline formations, which are the sandstone-dominant Fluvial Conglomerate and Sandstone (FCSS) and Shallow Marine Sandstone (SMSS) in ascending order. The results of the three-dimensional geologic modeling show that the six geologic formations are distributed very complicatedly both onshore and offshore with irregular depths and thicknesses, and they are partly dissected and offset by the eight major faults. The two clastic saline formations FCSS and SMSS are deep and thick at the three prospective areas such as Areas 1, 2, and 3 in the modeling domain. The results of the grid-based Monte Carlo simulation show the following three main contents. First, in the two clastic saline formations SMSS and FCSS, CO<SUB>2</SUB> exists as gas, liquid, and supercritical phases with the corresponding distinctive density ranges depending on the pressure and temperature with depth. Second, the theoretical multi-fluid-phase CO<SUB>2</SUB> storage capacities of the SMSS and FCSS all show asymmetric normal distributions. On the other hand, the effective multi-fluid-phase CO<SUB>2</SUB> storage capacities of the saline formations all show log-normal distributions, and their values are much lower than the values of the theoretical multi-fluid-phase CO<SUB>2</SUB> storage capacities. The mean theoretical fluid-phase CO<SUB>2</SUB> storage capacities of the SMSS and FCSS are equal to 2,511.60 Mton and 1,370.91 Mton, respectively. The mean effective fluid-phase CO<SUB>2</SUB> storage capacities of the SMSS and FCSS are equal to 64.19 Mton and 35.32 Mton, respectively. Third, in the SMSS, the grid-wise (elemental) median theoretical and effective multi-fluid-phase CO<SUB>2</SUB> storage capacities are probabilistically higher at Area 1 (mainly as supercritical and liquid phases), intermediate at Area 2 (mainly as liquid and gas phases), and lower at Area 3 (mainly as a gas phase). However, in the FCSS, the grid-wise median theoretical and effective multi-fluid-phase CO<SUB>2</SUB> storage capacities are probabilistically higher at Area 2 (mainly as supercritical and liquid phases), intermediate at Area 1 (mainly as a supercritical phase), and lower at Area 3 (mainly as a gas phase). Finally, four key criteria (parameters) for selecting or ranking the optimal CO<SUB>2</SUB> storage locations are decided by summarizing and analyzing the results of the three-dimensional geologic modeling and grid-based Monte Carlo simulation. On the basis of the four key criteria (parameters), the overall suitability ranks of Areas 1, 2, and 3 for geologic CO<SUB>2</SUB> storage are determined to be the first, second, and third, respectively.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A series of three-dimensional geologic modeling and grid-based Monte Carlo simulation as a linked methodology is presented to evaluate the multi-fluid-phase CO<SUB>2</SUB> storage capacities of the two saline formations in the Pohang Basin. </LI> <LI> The saline formations are distributed very complicatedly with irregular depths and thicknesses and are partly dissected and offset by eight major faults. </LI> <LI> In the saline formations, CO<SUB>2</SUB> exists as gas, liquid, and supercritical phases with the distinctive density ranges depending on the pressure and temperature with depth. </LI> <LI> The theoretical and effective gas-, liquid-, supercritical-, and fluid-phase CO<SUB>2</SUB> storage capacities of the saline formations are evaluated probabilistically and spatially. </LI> <LI>

      • SCISCIESCOPUS

        Kawasaki Disease in Korea, 2003–2005

        Park, Yong-Won,Han, Ji-Whan,Park, In-Sook,Kim, Chang-Hwi,Cha, Sung-Ho,Ma, Jae-Sook,Lee, Joon-Sung,Kwon, Tae-Chan,Lee, Sang-Bum,Kim, Chul-Ho,Lee, Heung-Jae,Yun, Yong-Soo Lippincott Williams Wilkins, Inc. 2007 PEDIATRIC INFECTIOUS DISEASE JOURNAL Vol.26 No.9

        PURPOSE:: The aim of this study was to investigate the incidence rate and epidemiologic patterns of Kawasaki disease in Korea for the 3-year-period, 2003–2005. METHODS:: The questionnaire for an epidemiologic survey on Kawasaki disease was distributed to all 102 Korean hospitals that conduct pediatric residency programs, and obtained data were analyzed upon receipt. RESULTS:: The 9662 patients of Kawasaki disease from 85 hospitals that responded (response rate, 83.3%) consisted of 5877 males and 3785 females (male:female ratio, 1.55:1). The incidence rate per 100,000 children <5-year-old was 104.2 in 2003, 106.4 in 2004, and 104.6 in 2005 (average rate, 105.0). Their mean age of onset was 33.3 months, and the proportions of sibling cases and recurrent cases were 0.29% and 2.0%, respectively. Coronary arterial abnormalities were detected at follow-up by echocardiogram in 18.8% of all such cases including dilatations of 18.0% and aneurysms of 2.5%. CONCLUSION:: The average annual rate of incidence, 105.0/100,000 in children <5-year-old is the second highest reported rate in the world.

      • KCI등재

        Long-term Outcome of Microscopic Transsphenoidal Surgery for Prolactinomas as an Alternative to Dopamine Agonists

        Park Kawngwoo,Park Kwang Hyon,Park Hye Ran,Lee Jae Meen,Kim Yong Hwy,Kim Dong-Young,Won Tae-Bin,Kong Sung Hye,Kim Jung Hee,Shin Chan Soo,Paek Sun Ha 대한의학회 2021 Journal of Korean medical science Vol.36 No.15

        Background: Although long-term dopamine agonist (DA) therapy is recommended as a first-line treatment for prolactinoma, some patients may prefer surgical treatment because of the potential adverse effects of long-term medication, or the desire to become pregnant. This study aimed to determine whether surgical treatment of prolactinomas could be an alternative to DA therapy. Methods: In this retrospective study, 96 consecutive patients (74 female, 22 male) underwent primary pituitary surgery without long-term DA treatment for prolactinomas at a single institution from 1990 to 2010. All patients underwent primary surgical treatment in the microscopic transsphenoidal approach (TSA). Results: The median age and median follow-up period were 31 (16–73) years and 139.1 (12.2–319.6) months, respectively. An initial overall remission was accomplished in 47.9% (46 of 96 patients, 33 macroadenomas, and 13 microadenomas) of patients. DA dose reduction was achieved in all patients after TSA. A better remission rate was independently predicted by lower diagnostic prolactin levels and by a greater extent of surgical resection. Overall remission at the last follow-up was 33.3%, and the overall recurrence rate was 30.4%. The permanent complication rate was 3.1%, and there was no mortality. Conclusion: TSA can be considered a safe and potentially curative treatment for selective microprolactinomas as an alternative to treatment with a long-term DA.

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