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김재덕,서요섭,김진수 대한구강악안면방사선학회 2008 Imaging Science in Dentistry Vol.38 No.2
The basal cell nevus syndrome (BCNS) is an autosomal dominant disorder, characterized by basal cell carcinomas, odontogenic keratocysts and skeletal abnormalities. We experienced two cases that represented several characteristics of BCNS. Case 1: a thirty three year-old man visited CSU hospital. His radiographs showed four cystic lesions at both maxillary sinus and both mandibular angle, with bifid rib and ectopic calcification of falx cerebri. After marsupialization and enucleation, recurrent and newly developing tendency were found on his follow-up radiographs. Case 2: a seventeen year-old man had four large cystic lesions which were diagnosed as odontogenic keratocysts. He had craniofacial anomalies which included ectopic calcification and frontal bossing.
Case Report : Periosteal osteoblastoma of the mandible mimicking an osteoma: Case report
( Yo Seob Seo ),( Jae Duk Kim ),( Jin Soo Kim ) 조선대학교 구강생물학연구소 2013 Oral Biology Research (Oral Biol Res) Vol.37 No.2
Osteoblastomas are uncommon tumors that account for approximately 1% of all primary bone tumors. This report presents the cone-beam computed tomography (CBCT) findings of an osteoblastoma of the coronoid process of the mandible. Initially, this lesion was judged as an osteoma. CBCT images revealed a large mass with multiple internal calcifications. Histopathological examination of the lesion confirmed it as an osteoblastoma.
Yo-Seob Seo,In-A Cho,Tae-Hyeon Kim,Jae-Seek You,Ji-Su Oh,Gyeong-Je Lee,Do Kyung Kim,Jae-Sung Kim 대한생리학회-대한약리학회 2020 The Korean Journal of Physiology & Pharmacology Vol.24 No.3
The aim of the present study was to investigate the pathophysiological etiology of osteoarthritis that is mediated by the apoptosis of chondrocytes exposed to 25-hydroxycholesterol (25-HC), an oxysterol synthesized by the expression of cholesterol-25-hydroxylase (CH25H) under inflammatory conditions. Interleukin-1β induced the apoptosis of chondrocytes in a dose- dependent manner. Furthermore, the production of 25-HC increased in the chondrocytes treated with interleukin-1β through the expression of CH25H. 25-HC decreased the viability of chondrocytes. Chondrocytes with condensed nucleus and apoptotic populations increased by 25- HC. Moreover, the activity and expression of caspase-3 were increased by the death ligand-mediated extrinsic and mitochondria-dependent intrinsic apoptotic pathways in the chondrocytes treated with 25-HC. Finally, 25-HC induced not only caspasedependent apoptosis, but also induced proteoglycan loss in articular cartilage ex vivo cultured rat knee joints. These data indicate that 25-HC may act as a metabolic pathophysiological factor in osteoarthritis that is mediated by progressive chondrocyte death in the articular cartilage with inflammatory condition.
Thermoluminescent dosimetry of panoramic radiography
( Yo-seob Seo ),( Sun-kyoung Yu ) 조선대학교 치의학연구원(구 조선대학교 구강생물학연구소) 2021 Oral Biology Research (Oral Biol Res) Vol.45 No.1
This study aims to calibrate a thermoluminescence dosimeter (TLD) using a diagnostic radiation device and evaluate the dose of panoramic radiography. TLD-100s were calibrated using a solid-state dosimeter (Unfors Mult-O-Meter 512L; Unfors Instruments, Billdal, Sweden) and a diagnostic radiation device (HDT-500R; Hyun Dai Medical X-ray Co., Paju, Korea). Forty eight TLDs were placed in 24 sites of a head and neck phantom of a male (ART-210; Radiology Support Devices Inc., Long Beach, CA, USA), and panoramic radiation was performed under exposure parameters of 70 kVp and 10 mA using a ProMax (Planmeca, Helsinki, Finland). Using the International Commission on Radiological Protection (ICRP) 2007 recommendation, the effective dose of panoramic radiography was calculated from the absorbed doses of the tissues of the 24 TLD sites in a head and neck phantom. The absorbed dose of the TLD site was higher in the parotid gland (right: 1854.4 µGy, left: 1788.9 µGy) and lower in the calvarium anterior (3.8 µGy). The effective dose was calculated at 28.4 µSv. The cancer and heritable risks were 1.56×10-6 and 5.67×10-8, respectively. The TLD was calibrated using a diagnostic radiographic device, and the panoramic radiographic dose was evaluated. The findings of this study could be helpful in future dose studies.
증후군이 없는 40대 환자에 발생한 양측성 함치성낭: 증례보고 및 문헌고찰
서요섭 ( Yo Seob Seo ),성건화 ( Kun Hwa Sung ),김진수 ( Jin Soo Kim ) 조선대학교 구강생물학연구소 2012 Oral Biology Research (Oral Biol Res) Vol.36 No.1
Dentigerous cysts, the most commonly occurring developmental cysts of the jaw, develop in association with impacted teeth. However, in the absence of a syndrome, occurrence of bilateral dentigerous cystsis rare;approximately 23 cases have been described in the literature. Development of bilateral dentigerous cysts after the fi fth decade is extremely rare. We report on a rare case of bilateral non-syndromic dentigerous cysts associated with both mandibular third molars of a 49 year-old man.
조사야에 따른 cone-beam computed tomography의 흡수선량 비교
서요섭 ( Yo Seob Seo ),김재덕 ( Jae Duk Kim ),김진수 ( Jin Soo Kim ) 조선대학교 치의학연구원 2013 Oral Biology Research (Oral Biol Res) Vol.37 No.1
To compare absorbed doses of cone-beam computed tomography (CBCT) according to field of view (FOV). Materials and Methods: To measure the absorbed doses of CBCT (Hitachi Medical Co.), we placed thermoluminescent dosimeter chips on both the submandibular and parotid glands, esophagus, tongue, and thyroid gland in a dental head phantom (CIRS). We used three image acquisition modes with FOV of different size: panoramic mode (P mode), implant mode (I mode), and dental mode (D mode). Two different dental mode scans were performed. One scanned the right upper molar region (D1), whereas the other scanned the left lower molar region (D2). Results: Average absorbed doses was lowest in D mode (average of D1 and D2, 4272.1 μGy) (p<0.05). Although the averages of absorbed doses between D1 and D2 showed no significant difference (p>0.05), the absorbed doses of esophagus (D1 756.9 μGy, D2 2938.2 μGy) and thyroid gland (D1 344.6 μGy, D2 880.1 μGy) were significantly different between D1 and D2. Conclusion: Since the average of absorbed doses was lowest with the smallest FOV, we must try to select the lowest FOV as possible when performing computed tomography, followed by careful diagnosis.