Numerical Calculation of Stator End Leakage Reactance of Permanent Magnet Machines with Concentric Winding

Xiaoqin Zheng,Wen Zhang,Xinzhen Wu,Ronggang Ni 한국자기학회 2019 Journal of Magnetics Vol.24 No.1

Concentric winding has been widely used in small capacity AC motors due to its excellent performance. In this paper, a numerical calculation method based on the magnetic vector potential is proposed to calculate the stator end leakage reactance of concentric winding. In this case, the basic unit of numerical calculation becomes the coil group rather than the coil since concentric windings have different coil sizes. The calculated stator end leakage reactance of a prototype three-phase permanent magnet machine with concentric winding is validated using the finite element method. Compared to 3D electromagnetic field calculation, the proposed method does not require a complex modeling process and is therefore highly efficient computationally, requiring only a fraction of the calculation time.

An Energy-efficient Competitive Clustering Algorithm for Wireless Sensor Networks using Mobile Sink

Jin Wang,Xiaoqin Yang,Tinghuai Ma,Menglin Wu,Jeong-Uk Kim 보안공학연구지원센터(IJGDC) 2012 International Journal of Grid and Distributed Comp Vol.5 No.4

Phosphate Solubilization and Gene Expression of Phosphate-Solubilizing Bacterium Burkholderia multivorans WS-FJ9 under Different Levels of Soluble Phosphate

( Qingwei Zeng ),( Xiaoqin Wu ),( Jiangchuan Wang ),( Xiaolei Ding ) 한국미생물 · 생명공학회 2017 Journal of microbiology and biotechnology Vol.27 No.4

Phosphate-solubilizing bacteria (PSB) have the ability to dissolve insoluble phosphate and enhance soil fertility. However, the growth and mineral phosphate solubilization of PSB could be affected by exogenous soluble phosphate and the mechanism has not been fully understood. In the present study, the growth and mineral phosphate-solubilizing characteristics of PSB strain Burkholderia multivorans WS-FJ9 were investigated at six levels of exogenous soluble phosphate (0, 0.5, 1, 5, 10, and 20 mM). The WS-FJ9 strain showed better growth at high levels of soluble phosphate. The phosphate-solubilizing activity of WS-FJ9 was reduced as the soluble phosphate concentration increased, as well as the production of pyruvic acid. Transcriptome profiling of WS-FJ9 at three levels of exogenous soluble phosphate (0, 5, and 20 mM) identified 446 differentially expressed genes, among which 44 genes were continuously up-regulated when soluble phosphate concentration was increased and 81 genes were continuously down-regulated. Some genes related to cell growth were continuously up-regulated, which would account for the better growth of WS-FJ9 at high levels of soluble phosphate. Genes involved in glucose metabolism, including glycerate kinase, 2-oxoglutarate dehydrogenase, and sugar ABC-type transporter, were continuously down-regulated, which indicates that metabolic channeling of glucose towards the phosphorylative pathway was negatively regulated by soluble phosphate. These findings represent an important first step in understanding the molecular mechanisms of soluble phosphate effects on the growth and mineral phosphate solubilization of PSB.

Acoustic localization of surface defect for low-speed large bearing with averaged generalized inverse beamforming

Xiang Guo,Xing Wu,Xiaoqin Liu,Linjiang Tang 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.1

Using microphone array to detect the fault of rotating machinery is an effective method. Compared with the fault diagnosis based on vibration analysis, the advantage of this method is that it does not need the direct contact between the sensor and the machine. In addition, acoustic location can be realized by using microphone array, to accurately identify the sound radiation source on the machine surface. Conventional beamforming (CBF) is widely applied in noise source identification because of its fast speed. In the local reverberation environment, the conventional beamforming is disturbed by the image source, causing inaccurate judgment of the fault location and low imaging resolution. In this paper, an acoustic imaging method of averaged generalized inverse beamforming (AGIB) is proposed. Compared with CBF, generalized inverse beamforming (GIB) possess higher location accuracy. First, the spectral kurtosis (SK) can enhance the impact characteristics of fault signals. According to the center frequency and bandwidth estimated by the spectral kurtosis diagram, the impact information which adopt in beamforming location can be extracted in time domain and frequency domain by spectral kurtosis matched filter. Then the average amplitude and standard deviation of generalized inverse beamforming output at different positions are calculated. Finally, the normalized standard deviation is used for the beamforming output weighting of the central measurement position, so as to enhance the spatially invariant source contribution and effectively attenuate the ghost caused by the local reverberation environment. Through defect location of low-speed large bearing, compared with the averaged conventional beamforming (ACBF), AGIB can not only overcome the influence of local reverberation environment and accurately locate the fault location, but also improve the resolution significantly.

Transcriptomic analysis reveals the molecular mechanism of apoptosis induced by Muscovy duck reovirus

Quanxi Wang,Baocheng Wu,Mengxi Liu,Xiaoqin Yuan,Chunyan Li,Shiyi Chen,Yubin Zhuang,Yijian Wu,Yifan Huang 한국유전학회 2017 Genes & Genomics Vol.39 No.11

This study was to investigate the molecular mechanism underlying the apoptosis induced by Muscovy duck reovirus (MDRV) through a transcriptomic analysis. Muscovy ducklings were infected with MDRV strain YB and the apoptotic cells in their livers were examined with terminal-deoxynucleotidyl-transferase-mediated nick end labeling and flow cytometry. Genes differentially expressed in the livers of the MDRV-infected ducklings were screened by comparing them with those of uninfected ducklings and were analyzed with a transcriptomic method to illuminate the mechanism of MDRV infection. The results showed that MDRV infection strongly induced apoptotic cells in liver. Significant pathway enrichment determined by a Kyoto Encyclopedia of Genes and Genomes analysis showed that MDRV activated the death receptor family signaling pathway (Fas, TNFR1), the interleukin receptor signaling pathway (IL1, IL3), the phosphatidylinositol 3-kinase signaling pathway, NF-ҝB signaling pathway and calcium ions signaling pathway to induce apoptosis. This was verified by SYBR-Green-based fluorescence quantitative PCR. In conclusion, MDRV induce apoptosis by activation multi signaling pathways.

Mitochondrial dysfunction is underlying fluoroquinolone toxicity: an integrated mitochondrial toxicity assessment

Jiang Tianyi,Kustermann Stefan,Wu Xiaoqin,Zihlmann Christine,Zhang Meifang,Mao Yi,Wu Waikwong,Xie Jianxun 대한독성 유전단백체 학회 2023 Molecular & cellular toxicology Vol.19 No.2

Background Antibiotics bear an inherent risk of mitochondrial toxicity due to the structural similarities between mitochondria and bacteria. Drug-induced mitochondrial dysfunction can contribute to organ toxicity and has resulted in a considerable number of market withdrawals. Fluoroquinolones were alerted for hepatotoxicity liability and were recently given black box warnings by FDA for the potential disabling side eff ects including tendonitis, pain in extremities and joints, neuropathies associated with paraesthesia, depression, impairment of memory, hearing, vision, etc. Objective In this study, the potential involvement of mitochondrial impairment in the toxicity of four fl uoroquinolones was investigated with a panel of mechanistic endpoints including ATP, mitochondrial respiration, as well as mitochondrial DNA and protein levels. Results Data revealed mitochondrial toxicity to diff erent extents, induced by the tested fl uoroquinolones and suggested mitochondrial protein synthesis as potential mechanism of action. Conclusion This study exemplifi es an integrated/holistic approach with a selected battery/panel of in vitro assays/endpoints serving to identify mitochondrial toxicity early on in the development of drugs, in particular, antibiotics.

Numerical Investigations of Turbulent Flows around Hydrofoil by Using Implicit Large Eddy Simulation

Xuelin Tang,Gao Hui,Wu Zhixing,Hao Man,Shi Xiaoyan,Li Xiaoqin 한국유체기계학회 2018 International journal of fluid machinery and syste Vol.11 No.3

Based on Implicit Large Eddy Simulation (ILES), the Adaptive Local Deconvolution Method (ALDM) was proposed to develop an implicit Sub-Grid Scale (SGS) model for three-dimensional (3D) turbulent unsteady flow around the NACA0012 Hydrofoil at a high Reynolds number of 2400,000. With the help of User Define Function (UDF) of the Fluent CFD software, the 3D turbulent unsteady flows were carried out by using ILES and LES respectively. The lift coefficients predicted by both models were in good agreement with the experimental data and the relative error of lift coefficient predicted by both models decreases firstly and then increases with the increase of the incident angle, but the numerical results by ILES were more close to the experimental, which verified the feasibility and accuracy of the ILES model. In addition, the predicted pressure contour and streamline distributions by ILES and LES at different incident angles in a wide range were also investigated further. The larger of the incident angle, the production and shedding of the vortex are stronger. The predicted results by both the models have the similar tendency, and the ILES could more finely capture the flow patterns. For a large incident angle of 20°, the internal flow analyses by ILES could well reproduce the whole process of the vortex from generation to development and shedding around the hydrofoil.

EST-SSRs characterization and in-silico alignments with linkage map SSR loci in Grape (Vitis L.) genome

Hong Huang,Xia Xu,Xiaoqin Yang,Shuang Liang,Jiao Wu,Jiang Lu 한국유전학회 2012 Genes & Genomics Vol.34 No.1

11,581 grape (Vitis L.) EST-SSRs were produced and characterized from a total of 381,609 grape ESTs. Among the EST-SSRs, the tri repeat (5,560, 45.4%) represented the most abundant class of microsatellites in grape EST. Most of grape EST-SSR motifs fall within 18-24 bps in length. The EST-SSRs tri- repeats occurred a higher percentage in 5'-end (59.3%) than in 3'-end (48.3%). And EST-SSR tri- repeats had abundant codon repeats for putative amino acid runs as Proline, Arginine in grape ESTs. To better utilizing these markers, 142 of newly developed and validated EST SSR loci as well as 223 linkage map SSR loci were in silico aligned and mapped in grape genome. The orders of these SSR loci in the chromosomal physical locations and in the linkage groups were compared, and about twenty linkage map loci positions were switched or rearranged in grape genome. The EST-SSR markers extended the linkage map in grape genome. The method of in silico mapping reported in this study provided an initial collection for grape mapping resources. This approach offers great opportunities to understand the genetic variations in nucleotide sequences differences in physical map,and genetic recombination in linkage maps, as well as benefits for markers enrichment in a specific grape genome region for fine mapping or QTL mapping.

Depression and Survival in Chinese Patients with Gastric Cancer: A Prospective Study

Yu, Hui,Wang, Yaoxian,Ge, Xin,Wu, Xiaoke,Mao, Xiaoqin Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.1

Aim: Depression is thought to be a predictor of poor survival among cancer patients. In our study, we aimed to investigate the association between depression and survival in patients with gastric cancer. Methods: The subjects were a total of 300 patients aged 20-75 years who had histological confirmed diagnosis of gastric cancer from January 2004 to May 2006. Three months after patients diagnosis, depression was scored using by the Depression Status Inventory (DSI) designed by Willian WK Zung. The follow-up period consisted of a total of 13,643 person-months. A Cox's regression analysis was used to assess the association between depression and survival. Results: The percentage of subjects with depression according to the DSI depression criteria was 31%. Tumor stage and treatment methods were significantly associated with depression of patients. Age (60 years or older), annual income, tumor stage, lymph nodes metastasis and treatment were significantly associated with increased hazard ratio (HR) for gastric cancer survival. The adjusted HR for mortality risk in gastric cancer patients with depression tended to be high (HR=3.34, 95% CI=1.23-5.49) and a significant trend was found (P<0.05). Conclusion: The data obtained in this prospective study in Chinese support the hypothesis that depression is associated with poor survival among gastric cancer patients. Further studies with a large sample and longer term follow-up period are needed.

Gram-positive Rhizobacterium Bacillus amyloliquefaciens FZB42 Colonizes Three Types of Plants in Different Patterns

Ben Fan,Rainer Borriss,Wilfrid Bleiss,Xiaoqin Wu 한국미생물학회 2012 The journal of microbiology Vol.50 No.1

The colonization of three types of different plants, Zea mays, Arabidopsis thaliana, and Lemna minor, by GFP-labeled Gram-positive rhizobacterium Bacillus amyloliquefaciens FZB42 was studied in gnotobiotic systems using confocal laser scanning microscopy and electron microscopy. It was demonstrated that FZB42 was able to colonize all the plants. On one hand, similar to some Gram-negative rhizobacteria like Pseudomonas, FZB42 favored the areas such as the concavities in root surfaces and the junctions where lateral roots occurred from the primary roots; on the other hand, we clearly demonstrated that root hairs were a popular habitat to the Gram-positive rhizobacterium. FZB42 exhibited a specific colonization pattern on each of the three types of plants. On Arabidopsis, tips of primary roots were favored by FZB42 but not so on maize. On Lemna, FZB42 accumulated preferably along the grooves between epidermal cells of roots and in the concave spaces on ventral sides of fronds. The results suggested L. minor to be a promising tool for investigations on plant-microbial interaction due to a series of advantages it has. Colonization of maize and Arabidopsis roots by FZB42 was also studied in the soil system. Comparatively, higher amount of FZB42 inoculum (~108 CFU/ml) was required for detectable root colonization in the soil system, where the preference of FZB42 cells to root hairs were also observed.