외국문헌초록 : 오존 산화와 BAF를 이용한 Acid Rose Dye를 포함한 염색폐수의 처리

( Xiao Jun Wang ),( Xiao Yang Gu ),( De Xian Lin ),( Fang Dong ),( Xiao Fang Wan ) 한국수처리학회(구 한국수처리기술연구회) 2007 한국수처리학회지 Vol.15 No.1

Effect of the Oxygen Flux Ratio on the Structural and the Optical Properties of Silver-oxide Films Deposited by Using the Direct-current Reactive Magnetron Sputtering Method

Xiao-Yong Gao,Hong-Liang Feng,Zeng-Yuan Zhang,Jiao-Min Ma,Meng-Ke Zhao,Chao Chen,Jin-Hua Gu,Shi-E Yang,Yong-Sheng Chen,Jing-Xiao Lu 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.2

Using values of the oxygen flux ratio (OFR = [O2]/[Ar]) ranging from 0 to 0.5, authors deposited a series of silver-oxide (Ag_xO) films on glass substrates by direct-current reactive magnetron sputtering (DC sputtering) at a substrate temperature of 150 ℃. The effect of the OFR on the film’s structural and optical properties was systematically investigated by using X-ray diffractometry, scanning electron microscopy and spectrophotometry. The Ag_xO films deposited clearly show an evolution of the film’s phase structure from the biphased (Ag + Ag_2O) structure to the biphased (AgO + Ag_2O) structure and then to the single-phased (Ag_2O) structure as value of the OFR increases. Accordingly, the film’s surface morphology, related to the film’s crystalline structure, clearly changes from a loose and porous surface structure to a compact surface structure and then to a pyramid-like surface structure with increasing value of the OFR. The novel porous structure may be attributed to the interruption of the silver’s growth course by the AgO on the film’s surface. Notably, a single-phased Ag_2O film is deposited by DC-sputtering at OFR = 0.5 due to the dual effects of thermal decomposition of the AgO phase and a combination reaction of AgO and Ag to Ag_2O. The oscillations both in the film’s reflectivity and transmissivity spectra are strengthened with increasing OFR, indicating an evolution from the metallic behavior of the biphased (Ag + Ag_2O) film to the dielectric behavior of the biphased (Ag_2O + AgO) film and the single-phased Ag2O film. The fitted optical absorption edges of the Ag_2O and the Ag_xO films deposited at values of the OFR of 0.5 and 0.33 are approximately 2.43 eV and 2.34 eV, respectively. The absorption edges are closely related to the direct interband transitions.

Applicative Value of Serum CA19-9, CEA, CA125 and CA242 in Diagnosis and Prognosis for Patients with Pancreatic Cancer Treated by Concurrent Chemoradiotherapy

Gu, Yu-Lei,Lan, Chao,Pei, Hui,Yang, Shuang-Ning,Liu, Yan-Fen,Xiao, Li-Li Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.15

Objective: To evaluate the application value of serum CA19-9, CEA, CA125 and CA242 in diagnosis and prognosis of pancreatic cancer cases treated with concurrent chemotherapy. Materials and Methods: 52 patients with pancreatic cancer, 40 with benign pancreatic diseases and 40 healthy people were selected. The electrochemiluminescence immunoassay method was used for detecting levels of CA19-9, CEA and CA125, and a CanAg CA242 enzyme linked immunoassay kit for assessing the level of CA242. The Kaplan-Meier method was used for analyzing the prognostic factors of patients with pancreatic cancer. The Cox proportional hazard model was applied for analyzing the hazard ratio (HR) and 95% confidential interval (CI) for survival time of patients with pancreatic cancer. Results: The levels of serum CA19-9, CEA, CA125 and CA242 in patients with pancreatic cancer were significantly higher than those in patients with benign pancreatic diseases and healthy people (P<0.001). The sensitivity of CA19-9 was the highest among these, followed by CA242, CA125 and CEA. The specificity of CA242 is the highest, followed by CA125, CEA and CA19-9. The sensitivity and specificity of joint detection of serum CA19-9, CEA, CA125and CA242 were 90.4% and 93.8%, obviously higher than single detection of those markers in diagnosis of pancreatic cancer. The median survival time of 52 patients with pancreatic cancer was 10 months (95% CI7.389~12.611).. Patients with the increasing level of serum CA19-9, CEA, CA125, CA242 had shorter survival times (P=0.047. 0.043, 0.0041, 0.029). COX regression analysis showed that CA19-9 was an independent prognostic factor for patients with pancreatic cancer (P=0.001, 95%CI 2.591~38.243). Conclusions: The detection of serum tumor markers (CA19.9, CEA, CA125 and CA242) is conducive to the early diagnosis of pancreatic cancer and joint detection of tumor markers helps improve the diagnostic efficiency. Moreover, CA19-9 is an independent prognostic factor for patients with pancreatic cancer.

REAL SOLUTIONS OF THE EQUATION (equation omitted)

Yang, Zhong-Peng,Cao, Chong-Gu,Tang, Xiao-Min 한국전산응용수학회 2003 Journal of applied mathematics & informatics Vol.13 No.1

For an n ${\times}$ n real matrix X, let ${\Phi}$(X) = X o (X$\^$-1/)$\^$T/, where o stands for the Hadamard (entrywise) product. Suppose A, B, G and D are n ${\times}$ n real nonsingular matrices, and among them there are at least one solutions to the equation (equation omitted). An equivalent condition which enable (equation omitted) become a real solution ot the equation (equation omitted), is given. As application, we get new real solutions to the matrix equation (equation omitted) by applying the results of Zhang. Yang and Cao [SIAM.J.Matrix Anal.Appl, 21(1999), pp: 642-645] and Chen [SIAM.J.Matrix Anal.Appl, 22(2001), pp:965-970]. At the same time, all solutions of the matrix equation (equation omitted) are also given.

Pu-Erh Tea Hot-Water Extract Activates Akt and Induces Insulin-Independent Glucose Transport in Rat Skeletal Muscle

Xiao Ma,Satoshi Tsuda,Xin Yang,Ning Gu,Hiroko Tanabe,Rieko Oshima,Tetsuya Matsushita,Tatsuro Egawa,Ai-Jun Dong,Bei-Wei Zhu,Tatsuya Hayashi 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.3

Skeletal muscle is a major organ that is important for whole-body glucose metabolism. We found that when isolated rat epitrochlearis muscle was incubated with a Pu-erh tea hot-water extract (PTE) for 30 min, the rate of 3-O-methyl-D-glucose (3MG) transport increased in the absence of insulin. This activation was associated with an increase in Ser473 phosphorylation of Akt, a signaling intermediary leading to insulin-dependent glucose transport, but not Tyr458 phosphorylation of phosphoinositide 3-kinase p85, an upstream molecule of Akt. PTE-stimulated 3MG transport was also not accompanied by Thr172 phosphorylation of the catalytic α-subunit of 5′-AMP-activated protein kinase (AMPK). Gallic acid, a water-soluble ingredient in Pu-erh tea, stimulated Akt phosphorylation, but not AMPK phosphorylation. These results suggest that Pu-erh tea potentially promotes skeletal muscle glucose transport at least in part by activating Akt.

EFFECT OF CHARGE DENSITY ON SPRAY CHARACTERISTICS, COMBUSTION PROCESS, AND EMISSIONS OF HEAVY-DUTY DIESEL ENGINES

Bin Yang Wu,Qiang Zhan,Xiao Yang Yu,Wen Yu Gu,Min Zhang,Wanhua Su 한국자동차공학회 2018 International journal of automotive technology Vol.19 No.4

In-cylinder charge density at top dead center is an important parameter of diesel engines and is influenced by intake pressure, intake temperature, and compression ratio. The effects of charge density on fuel spray, combustion process, and emissions were investigated by using a constant volume bomb and a heavy-duty diesel engine. Spray development resistance increased with the increase of the charge density in the constant volume bomb. It was found that short spray penetration was accompanied by a large spray cone angle in the former stage with high charge density. However, the equivalence ratio was lowered and the degree of homogeneity of the mixture was increased in the later stage owing to the rapid interaction of fuel and gas at a high mixing rate. Combining the first law of thermodynamics and the second law of thermodynamics for analysis, as the charge density increased, the gross indicated thermal efficiency (ITEg) was improved. However, pumping loss had to be considered with higher charge density. Under this condition, the brake thermal efficiency (BTE) trend was increased initially and decreased subsequently. Under high-load operation (1200 r/min BMEP, 2.0 MPa), the minimum charge density value of 44.8 kg/m3 was found to be reasonable. This charge density was suitable for combustion and brought about minimum exhaust energy and trade-off emissions. Moreover, by analyzing two operation conditions in terms of the maximum BTE with the Miller and the conventional cycles, compression temperature and combustion temperature were reduced in the Miller cycle with the charge density 44.8 kg/m3. A high C p/C v could improve the cylinder exergy/power conversion process by its positive effect of increasing the specific heat ratio. Owing to the interaction between a high C p/C v and exergy loss to heat transfer, the condition with the minimal charge density could produce more piston work.

Effect of a Diet with Unrestricted Sodium on Ascites in Patients with Hepatic Cirrhosis

( Xi Bing Gu ),( Xiao Juan Yang ),( Hong Ying Zhu ),( Bo Yu Xu ) 대한소화기학회 2012 Gut and Liver Vol.6 No.3

Background/Aims: There has been debate on whether a sodium-restricted diet (SRD) should be used in cirrhotic patients with ascites in China in recent years. The purpose of this study was to compare the effect of sodium-restricted and unrestricted diets on plasma renin activity (PRA), renal blood flow (RBF) and ascites in patients with liver cirrhosis. Methods: Two hundred cirrhotic patients with ascites were randomly divided into two groups (98 cases in the sodium-unrestricted diet [SUD] group and 102 cases in the SRD group); 95 patients (96.94%) in the SUD group and 97 patients (95.1%) in the SRD group had post-hepatitis B cir-rhosis. Results: Blood sodium and RBF were higher in SUD group than in SRD group (p<0.001), while PRA were signifi-cantly lower in SUD group than the SRD group 10 days after treatment (p<0.001). Renal impairment caused by low blood sodium was higher in SRD group than in SUD group (p<0.01). Ascites disappeared in higher proportion of patients in SUD group than in SRD group (p<0.001). Conclusions: SUD can increase the level of blood sodium and RBF, and be benefi-cial to diuresis and ascite reduction and disappearance. (Gut Liver 2012;6:355-361)

Modified exosomal SIRPα variants alleviate white matter injury after intracerebral hemorrhage via microglia/macrophages

Xinjie Gao,Heng Yang,Weiping Xiao,Jiabin Su,Yuwen Zhang,He Wang,Wei Ni,Yuxiang Gu 한국생체재료학회 2022 생체재료학회지 Vol.26 No.4

Background: Despite limited efficiency, modulation of microglia/macrophages has shown to attenuate neuroinflammation after intracerebral hemorrhage (ICH). In this context, we evaluated the efficacy of modified exosomal signal regulatory protein α (SIRPα) variants (SIRPα-v Exos) in microglia/macrophages and neuroinflammation-associated white matter injury after ICH. Methods: SIRPα-v Exos were engineered to block CD47-SIRPα interactions. After obtaining SIRPα-v Exos from lentivirus-infected mesenchymal stem cells, C57BL/6 mice suffering from ICH underwent consecutive intravenous injections of SIRPα-v Exos (6 mg/kg) for 14 days. Afterwards, the volume of hematoma and neurological dysfunctions were assessed in mice continuously until 35 days after ICH. In addition, demyelination, electrophysiology and neuroinflammation were evaluated. Furthermore, the mechanisms of microglial regulation by SIRPα-v Exos were investigated in vitro under coculture conditions. Results: The results demonstrated that the clearance of hematoma in mice suffering from ICH was accelerated after SIRPα-v Exo treatment. SIRPα-v Exos improved long-term neurological dysfunction by ameliorating white matter injury. In addition, SIRPα-v Exos recruited regulatory T cells (Tregs) to promote M2 polarization of microglia/macrophages in the peri-hematoma tissue. In vitro experiments further showed that SIRPα-v Exos regulated primary microglia in a direct and indirect manner in synergy with Tregs. Conclusion: Our studies revealed that SIRPα-v Exos could accelerate the clearance of hematoma and ameliorate secondary white matter injury after ICH through regulation of microglia/macrophages. SIRPα-v Exos may become a promising treatment for ICH in clinical practice.

Clinical Observation of Three Dimensional Conformal Radiotherapy with Tamoxifen in Treatment of Postoperative Malignant Glioma

Zhou, Shao-Bing,Liu, Yang-Chen,Yin, Xiao-Xiang,Ding, Wen-Xiu,Guo, Xin-Wei,Gu, Liang,Huang, Xin-En Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5

Objective: To evaluate the efficacy and adverse effects of three dimensional conformal radiotherapy (3D-CRT) with tamoxifen in treating patients with postoperative malignant glioma. Patients and Methods: 60 patients of postoperative malignant glioma were randomly assigned into two groups, 30 patients were treated with 3D-CRT plus tamoxifen (treatment group), and the other 30 patients with 3D-CRT plus temozolomide (control group). All patients were radiated by 6MV X-ray, 2.0Gy per fraction, once daily, with a total dose (DT) of 56~60Gy. Tamoxifen was delivered at $60mg/m^2/d$, temozolomide was given at $75mg/m^2/d$. All patients were treated with concurrent radiotherapy. Results: One, 2, 3 year survival rates of treatment and control group were 63.3%, 30.0%, 23.0% and 70.0%, 33.3%, 26.7%, respectively (${\chi}^2=0.01$, 0.23, 0.09, P>0.05). The rate of thromboembolism in treatment group was 6.7%. Conclusion: Therapeutic efficacy of two groups was similar, but it was more cost-effective in treatment group, and toxicity did not increase.

Expression of C4.4A is a Potential Independent Prognostic Factor for Patients with Gastric Cancer

Cheng, Da-Qing,Gu, Xiao-Dong,Li, Zhen-Yang,Xiang, Jian-Bin,Chen, Zong-You Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.9

C4.4A, a metastasis-associated gene, encodes a glycolipid-anchored membrane protein which is overexpressed in several human malignancies. However, there are few data available on C4.4A expression and its relationship with progression in gastric cancer. Our study was designed to explore the expression of C4.4A in gastric cancer and to correlate it with clinical outcome. C4.4A expression was studied by quantitative real-time RT-PCR and immunohistochemistry for assessment of correlations with clinicopathological factors. C4.4A mRNA expression was significantly up-regulated in gastric cancer as compared with noncancerous tissue (p<0.05)., being observed in 107 (88.4%) of the 121 gastric cancer cases by immunohistochemistry. We found that the expression of C4.4A mRNA was correlated with size of the tumor, depth of invasion, lymph node metastasis, distant metastasis and TNM stage. Moreover, patients with overexpression of C4.4A has a significantly worse survival (p<0.05). Further multivariable analysis indicated that the expression of C4.4A was an independent prognostic indicator for gastric cancer (p<0.05). In conclusion, overexpression of C4.4A correlates with metastatic potential of gastric cancer and C4.4A could be a novel independent prognostic marker for predicting outcome.