백서의 치아이동 시 피질골 천공이 치주조직의 OPG, RANK, RANKL의 발현에 미치는 영향

박우경,김성식,박수병,손우성,김용덕,전은숙,박미화 대한치과교정학회 2008 대한치과교정학회지 Vol.38 No.3

치아이동 시 피질골 천공이 치조골 재형성에 미치는 영향을 알아보기 위해서 생후 15주된 자성백서를 사용하여 피질골 천공 후 치아이동을 실시한 실험군(Tooth movement with cortical punching: TMC group, n = 16)과 교정적 치아이동만 실시한 대조군(Tooth movement only group: TM group, n = 16)의 치아주위조직을 면역조직화학염색을 통하여 관찰하였다. 실험군과 대조군의 실험동물에 20 gm의 힘으로 상악 전치부 사이를 이개시키는 치아이동을 시행하였으며 실험군에서는 상악 전치부 구개부위에 피질골 천공을 실시하였다. 치아이동 후 1, 4, 7, 14일째에 실험군과 대조군의 실험동물을 희생시켰다. 면역조직화학염색법으로 OPG, RANK, RANKL의 발현을 비교한 결과, OPG의 발현은 양 군 모두에서 미처치 대조군에 비하여 감소되었으나, 실험군에서의 발현이 대조군보다 컸으며, RANK, RANKL은 피질골 천공을 시행한 경우에 더 강한 발현을 보이는 것이 관찰되었다. 따라서 피질골 천공이 치주조직의 OPG, RANK, RANKL의 발현에 영향을 미치며 치조골의 재형성을 향상시키는 것을 알 수 있었다. Objective: The purpose of this study was to investigate whether cortical punching could stimulate the expression of OPG, RANK, and RANKL during tooth movement by immunohistochemistry. Methods: 34 sprague-dawley rats (15 weeks old) were allocated into 3 groups: TMC group (experimental group; Tooth Movement with Corticotomy, n = 16), TM group (control group; Tooth Movement only group, n = 16), and non-treatment group (n = 2). 20 gm of orthodontic force was applied to rat incisors by inserting elastic bands. The duration of force application was 1, 4, 7 and 14 days. A microscrew (diameter 1.2 mm) was used for cortical punching of the palatal side of the upper incisors in the TMC group. Results: Distributions of OPG, RANK, and RANKL were evaluated by immunohistochemistry. OPG, RANK and RANKL were observed on experimental and control groups. On the compression side, the degree of the expression of OPG decreased in both groups. The expression of RANK was most prominent in the experimental group of day 4. The expression of RANKL was most intensive and extensive in the experimental group of day 7. However, the expression of OPG was decreased in the experimental and control groups compared to the non treatment group. The expression of OPG, RANK and RANKL after force application were decreased at day 14. Conclusions: These findings suggested that cortical punching might stimulate remodeling of alveolar bone during a 2 week period of tooth movement without any pathologic change.

Effect of Impact Velocity on Interface Characteristics of HT‑9 Steel Joints Fabricated by Magnetic Pulse Welding

Jun‑Woo Song,Jin‑Ju Park,Gyoung‑Ja Lee,Min‑Ku Lee,Kyu‑Hyun Park,Soon‑Jik Hong,Jung Gu Lee 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.3

The weldability window in magnetic pulse welding (MPW) is proposed for the end-closure joining of HT-9 steel tubularworkpieces. Based on both theoretical and experimental investigations, the impact velocity of the flyer tube at the momentof collision had a dominant effect on the bonding characteristics of the resultant joints and the optimal impact velocity wasestimated to be in the range of 265–290 m/s in this alloy system. Under the optimal process conditions, no leak was detectedduring helium leak testing. Moreover, the integrity of the joint interface was preserved until the tube section ruptured duringinternal pressure burst testing. For HT-9 steel, the ductile δ-ferrite phase produced by the localized interfacial melting duringMPW acted as an effective obstacle to crack propagation, thereby enhancing the fracture resistance of the joint interface. Allof the results demonstrated the high integrity and durability of the HT-9 steel tube assembly fabricated by the MPW process.

S-344 : The Role of Skeletal Muscle Mass in Development of Metabolic Syndrome

( Byung Sam Park ),( Jun Sung Moon ),( Ji Sung Yoon ),( Kyu Chang Won ),( Hyoung Woo Lee ) 대한내과학회 2013 대한내과학회 추계학술대회 Vol.2013 No.1

Introduction: It has been well known that abdominal adiposity is related with insulin resistance and greater risk of metabolic disorder. Skeletal muscle plays central role in insulin mediated glucose disposal of whole body, but we only know a little about the association between skeletal muscle mass and MetS (MetS). The aim of this study is to clarify the clinical role of skeletal muscle mass in developing MetS through using skeletal muscle parameters by body impedance analysis (BIA). Methods: 1,042 healthy adults aged from 20 to 75 years who visited Yeungnam university health promotion center from Jun. 2008 to Jun. 2010 were enrolled. 204 subjects who had prior MetS or chronic disease that can affect to skeletal muscle mass were excluded. After 24 months from baseline, the metabolic parameters were assessed and the development of MetS was diagnosed using modified NCEP-ATP III criteria. From the BIA (Inbody 720), we obtained skeletal muscle mass (SMM, Kg), body fat mass (BFM, Kg), and visceral fat area (VFA, cm2). Then, we had defined as follows; percent of skeletal muscle mass (SMM%, %): SMM (kg)/weight (Kg), skeletal muscle index (SMI, Kg/m2): SMM (Kg)/height (m)2, skeletal muscle to body fat ratio (MFR): SMM (kg)/BFM (Kg) and skeletal muscle to visceral fat ratio (SVR, Kg/cm2): SMM (Kg)/VFA (cm2) Results: Mean follow up periods were 28.7±5.4 months. Among total 838 subjects (46.9±9.9 years, M:F=477:361), 88 (10.5%) were newly diagnosed MetS. 5th quintile of the SMM%, MFR and SVR was associated with decreased risk of development of MetS after adjusting for confounding factors. Conclusion: Decreased skeletal muscle mass may play critical role in development of the MetS and not absolute amount of skeletal muscle mass but relative ratio to body composition may be more important.

한국 정신장애의 역학 조사 연구[I] : 각 정신장애의 유병률

조맹제,함봉진,김장규,박강규,정은기,서동우,김선욱,조성진,이준영,홍진표,최용성,박종익,이동우,이기철,배재남,신정호,정인원,박종한,배안,이충경 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.4

Objectives : This study aims to estimate the prevalence of the DSM-IV psychiatric disorders in Korean population using the Korean version of Composite International Diagnostic Interview (K-CIDI). Methods : Subjects were selected by taking multi-stage, cluster samples of 7,867 adult household residents, 18 to 64 years of age, in ten catchment areas. Total 78 trained interviewers administered the K-CIDI to the selected respondents, from June 1 to November30,2001. Results : Total 6,275 respondents completed the interview. Some 33.5% of respondents reported at least one lifetime disorder, 20.6% reported at least one-year disorder, and 16.7% reported at least one-month disorder. The most common lifetime disorders were alcohol abuse/dependence (17.24%), nicotine dependence/withdrawal (11.19%), specific phobia (5.16%), and major de-pressive disorder (4.25%). The lifetime prevalence of substance abuse/dependence (0.25%) and schizophrenia (0.16%) was very low. Nicotine and alcohol use disorder showed very high male/female ratio. Mood disorder and anxiety disorder were more prevalent among female than male. Conclusion : The prevalence of psychiatric disorders was high. In comparison with other studies, remarkable differences in distributions of psychiatric disorders across the areas and times were observed.

제 3 대구치 발치시 환자의 호흡 패턴이 스트레스 변화 양상에 미치는 영향

이상명,김형욱,박양호,김진철,박준우,이성준,안재목,Rhee, Sang-Myung,Kim, Hyung-Wook,Park, Yang-Ho,Kim, Jin-Cheol,Park, Jun-Woo,Rhee, Sung-Jun,Nyamdorj, Selenge,Ahn, Jae-Mok 대한구강악안면외과학회 2007 대한구강악안면외과학회지 Vol.33 No.5

Purpose: Heart rate variability(HRV) is the clinical consequence of various influences of the autonomic nervous system(ANS) on heart beat. HRV can estimate the potential physiologic rhythm from the interval between consecutive beats(RR interval or HRV data). It is known as RSA which represents respiration-related HR rhythmic oscillation. Previous studies demonstrated a specific breathing pattern(0.1Hz, 6breaths/min) to improve a physiological body condition related to the stress. In this paper, the level of stress would be evaluated in terms of three phases of the dental treatment, combined with 6breaths/min. Methods: These phases include before, during and after tooth extraction or anesthesia or something.36 patients' stresses were assessed using HRV stress analyzer in each phase in Kangdong Sacred Heart Hospital, and Chuncheon Sacred Heart Hospital, Hallym University Medical Center from Jun. to Sept. of 2007. HRV 5-min data collected were analyzed in time-domain and frequency-domain to evaluate the activity of autonomic nervous system(ANS) which represents the level of stress. Results: All HRV parameters including HF(high frequency), LF(low frequency) and LF/HF ratio showned a significant change affecting the ANS balance. There was a 6.4% difference between R(LF/HF)s on general breathing pattern for balance of Autonomic nervous system, but on controlled breathing pattern, 0.1Hz, was made narrow till 1.4%. The activity of ANS has increased by 1.4% on general breathing pattern, and by 2.9% on controlled breathing pattern, 0.1Hz. Conclusion: After analysis of preoperative stress changes and effect of breathing pattern of 0.1 Hz on the stress in 36 patients who have undergone third molar extraction, following was concluded. In the preoperative stage, the sympathetic change was the greatest?after the?anesthetic injection, and stress was relieved by controlling the breathing pattern to a frequency of 0.1Hz.

대학생의 스포츠 활동 참가유형에 따른 자아존중감 및 건강통제소재의 관계

박주영,김지연,이준우,백승옥 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this study was to analyze the relationships between self esteem and health locus of control in sports participation type of university students. The subjects of the study was selected by stratified cluster random sampling method from the sports participation located in Seoul ' Kyung-Ki area in universty students. Among them 400 students are contacted as sampies to be studied. 29 of them are not reviewed because of untimely response and doubted sincerity of their answers. The author used questions from Rosenberg's Self-Esteem Scale SES (10 Questions, 1965, translated, edited and standardized by Kim, gui-bong, Kim, young-soo, Kang, sung-gu, Park, joo-young, Kim, young-ho, 1999) and Wallston, Wallston and DeVellis Multidimentional health Locus of Control Scale (18 Questions, 1978) to analyze the sample with statistical calculations including descriptive statistics analysis, one-way ANOVA, multiple correlation analysis for the study. The study conclusions from this study summarized as follow: First, there were differences in university students sports participation type depending on their characteristics such as sex, height, and weight. Second, the sports participation type among university students has a significant difference on the self-esteem. Third, the sports participation type among universty students has a significant difference on the health locus of control(internal health locus of control). Forth, there is some relationships between mental-health and body-consciousness in sports participation type of university students.

가압성형을 위한 Zr(Y)O₂TZP/Zr(Ce)O₂TZP/뮬라이트계 현탁액의 분산 거동

박우경,전병세 慶南大學校 附設 工業技術硏究所 1999 硏究論文集 Vol.17 No.-

가압성형(Pressure Casting)에 의한 조성경사를 갖는 다층 Zr(Y,Ce)O₂TZP/뮬라이트 세라믹복합체의 제조를 위해 현탁액의 분산거동을 살펴보았다. 각 조성에 해당하는 현탁액의 분산안정성을 살펴보기 위하여 분산제(NaHMP) 함량을 각각 0~1 wt.% 첨가시켜 pH 변화와 제타 전위를 측정하였다. 그 결과, Zr(Y)O₂TZP, Zr(Ce)O₂TZP, 그리고 뮬라이트는 분산제의 함량을 각각 0.5wt.%, 0.8wt.%, 그리고 0.8wt.% 첨가하였을 때 최적의 분산 조건이 형성되었으며, 이때의 pH 값은 8(±0.2) 이었다. Zr(Y)O₂TZP/뮬라이트, Zr(Ce)O₂TZP/뮬라이트, 그리고 Zr(Y,Ce)O₂TZP/뮬라이트 현탁액에서 최적의 분산조건은 0.6wt.%(pH 8.2), 0.8wt.%(pH 8.2), 그리고 0.6wt.%(pH 8.2)이었다. The dispersion behavior of the suspensions for the pressure casting were investigated to fabricate mutilayer Zr(Y,Ce)O₂TZP/Mullite. A dispersing agent (NaHMP) was changed from 0 to 1 wt.%, and then pH and zeta potential was measured. As a result, the optimal contents of the dispersing agent for Zr(Y)O₂TZP, Zr(Ce)O₂TZP, and Mullite were 0.5wt.%, 0.8wt.%, and 0.8wt.% respectively, and the pH values were around 8(±0.2). The optimal contents of the dispersing agent for Zr(Y)O₂TZP/Mullite, Zr(Ce)O₂TZP/Mullite, and Zr(Y,Ce)O₂TZP/Mullite were 0.6wt.%(pH 8.2) 0.8wt.%(pH 8.2), and 0.6wt.%(pH 8.2), respectively.

Sol-Gel 스핀코팅법을 이용한 접촉연소식 마이크로 가스센서의 제작

박성진,이상문,임준우,이덕동 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

Catalytic gas sensor have been used for a long time due to their excellent sensitivity for gases. However, this type has a problem in power consumption. A new integrated catalytic gas sensor for detecting flammable gases or flammable vapours has been fabricated on silicon with thin film that is silicon nitride(1,500□)/ silicon oxide(3,000□)/ silicon nitride(1,500□) dielectric layer, and silicon micromachining techniques. A microsensor using sol-gel spin coated alumina film was fabricated. For this method, alumina film was improved porosity than other techniques, sputter. By adding catalyst solution in alumina sol, we have simple process and control catalytic quantity. Finally the power consumption of the fabricated device was about 100mW at the operating temperature.

시설참외 연작재배지 토양의 객토 및 심토반전이 토양 화학성 변화와 토양선층 억제효과에 미치는 영향

전한식,박우철,정재식 한국환경농학회 2002 한국환경농학회지 Vol.21 No.1

우리나라의 시설참외 수산지인 성주지역의 시설참외 연작 대책으로 객토와 심경에 의한 토양 화학성분의 변화와 뿌리혹선충 억제 효과를 조사한 결과는 다음과 같다. 시설참외 연작대책으로 많은 양의 객토를 함으로 EC는 4.30 dS/m에서 1.80 dS/m로 58%, 유효인산은 406mg/kg으로 55% 감축되고 유기물 함량이 16g/kg에서 11g/kg으로 31% 줄어 퇴비 등 각종 거름 시용량을 증가해야 하면 뿌리혹선충 밀도 억제효과는 1년 차 89%, 3년 차 84%, 5년 차 69%로 되어 근본 대책이 되지 못하면서 영농비 가중 및 환경 파괴의 문제가 수반되었다. 심토반전 효과도 객토와 비슷하여 EC 4.30 dS/m에서 1.98 dS/m로 54% 줄고 유효인산 406 mg/kg에서 329 mg/kg 으로 19% 줄었으며 뿌리혹선충 밀도 억제 효과는 처리 후 1년 차 71%, 3년 차 67%, 5년 차 42%가 되므로 처리 3년 이후에는 다른 대책이 필요하였다. To elucidate the effect of soil addition and subsoil plowing on the change of soil chemical properties and the reduction of root-knot nematode, this experiment carried out in continuous cropping field of protected oriental melon (Cucumis melo L). Soil addition reduced electric conductivity (E. C.) from 4.3 to 1.8 dS/m (58%), available P_2O_5 from 406 to 182 mg/kg (55%) and organic matter content from 16 to 11 g/kg (31%). Population densities of root-knot nematode in soil reduced as much as 89%, 84%, and 69% at first year, third years, and of five years later, respectively. The effects of subsoil plowing were similar to that of soil addition. E. C. and phosphate were reduced from 4.30 to 1.98 dS/m (54%) and phosphate from 406 to 329 mg/kg (19%), respectively. Population densities of root-knot nematode reduced as much as 71%, 67%, and 42% after 1, 3, and 5 years, respectively. Subsoil plowing reduced nematode densities only for three years.

2000-2008년 수도권 지역의 가와사끼병의 역학적 연구

박형준,김영대,김우경,송영환,김동욱,박용원 인제대학교 2009 仁濟醫學 Vol.30 No.-

Objectives : The aim of this study was to investigate the clinical features and epidemiologic pattern of Kawasaki disease(KD) in Seoul metropolitan area for the 9-year-period. Methods : An epidemiologic survey on KD was retrospectively performed. The questionnaire was sent to 3 hospitals including Seoul Paik hospital, Sanggye Paik hospital and Ilsan Paik hospital, and obtained data were analyzed. Results : Data from a total of 1,297 cases were collected. The male-to-female ratio was 1.33:1(741:556), and the mean age of onset was 32.2 months. The monthly number of patients was slightly higher in May, June and December. There was no sibling case and rate of recurrence cases was 2.31%(30/1,297), and the proportion of patients with KD among total hospitalized pediatric patients was 2.05%. Coronary arterialu..A) abnormalities were detected at follow-up by echocardiogram in 17.2%(204/1,185) of cases including 0.76% of aneurysms. Conclusion : Comparing with the data of the KD patients in Korea(1.48%), our data of 1,297 KD patients area showed higher proportion of patients with KD among total hospitalized pediatric patient(2.05%).