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      • SCIEKCI등재

        Comparative Study of Low Doses of Rosuvastatin and Atorvastatin on Lipid and Glycemic Control in Patients with Metabolic Syndrome and Hypercholesterolemia

        ( Jong Seon Park ),( Young Jo Kim ),( Ji Yong Choi ),( Yoon Nyun Kim ),( Teck Jong Hong ),( Dong Soo Kim ),( Ki Young Kim ),( Myung Ho Jeong ),( Jei Keon Chae ),( Seok Kyu Oh ),( In Whan Seong ) 대한내과학회 2010 The Korean Journal of Internal Medicine Vol.25 No.1

        Background/Aims: This multicenter, open-labeled, randomized trial was performed to compare the effects of rosuvastatin 10mg and atorvastatin 10mg on lipid and glycemic control in Korean patients with nondiabetic metabolic syndrome. Methods: In total, 351 patients who met the modified National Cholesterol Education Program Adult Treatment Panel 3 (NCEP ATP 3) criteria for metabolic syndrome with low-density lipoprotein cholesterol (LDL-C) levels≥130mg/dL were randomized to receive either rosuvastatin 10mg (n=173) or atorvastatin 10mg (n=178) for over 6 weeks. Results: After 6 weeks of treatment, greater reductions in total cholesterol (-35.94 ±11.38 vs. -30.07 ±10.46%, p<0.001), LDL-C (48.04 ±14.45 vs. 39.52 ±14.42%, p<0.001), non-high-density lipoprotein cholesterol (-42.93 ±13.15 vs. -35.52 ±11.76%, p<0.001), and apolipoprotein-B (-38.7 ±18.85 vs. -32.57 ±17.56%, p=0.002) levels were observed in the rosuvastatin group as compared to the atorvastatin group. Overall, the percentage of patients attaining the NCEP ATP 3 goal was higher with rosuvastatin as compared to atorvastatin (87.64 vs. 69.88%, p<0.001). Changes in glucose and insulin levels, and homeostasis model assessment of insulin resistance index were not significantly different between the two groups. The safety and tolerability of the two agents were similar. Conclusions: Rosuvastatin 10mg was more effective than atorvastatin 10mg in achieving NCEP ATP 3 LDL-C goals in patients with nondiabetic metabolic syndrome, especially in those with lower NCEP ATP 3 target level goals. (Korean J Intern Med 2010;25:27-35)

      • 우리나라 사이버 패션에 대한 연구-1994년 이후에 나타난 트랜드 중에서-

        이은영,이종련,홍윤택,Lee, Eun-Young,Lee, Jong-Lyun,Hong, Youn-Teck 배재대학교 자연과학연구소 1999 自然科學論文集 Vol.11 No.1

        94년 이후의 FASHION TREND는 여러요인의 상호작용으로 제안되어졌다. 이 경향은 과학의 발달로 인한 끊임없는 상상력에 기인하다. 그 중에서도 사이버 패션의 경향은 다음과 같은 현대 복식의 착장미를 보여주고 있다. . 파운데이션의 적용 . 구축적 컷팅 . 양면적인 요소들의 상호작용 등이 많이 표현되어 진다. After 94' Fashion Trend presented interaction of variety factors. It is based on continuous imagination that si caused development of science. Cyber fashion trend in these days trend. Among modern trend. We find clothing beauty in contemporary fashion trend. There are many expressions about interaction of dualistic factors and constructive cutting and application of foundation.

      • KCI등재

        한국인에서 전립선암으로 호르몬치료를 받는 환자의 대사성 변화

        박창후(Chang Hoo Park),성기택(Gi Teck Sung),김세영(Sea Young Kim),김성진(Sung Jin Kim),홍성우(Sungwoo Hong),김종원(Jongwon Kim),박창면(Chang Myon Park),김한권(Han Kwon Kim),박종연(Jong Yeon Park) 대한비뇨기종양학회 2010 대한비뇨기종양학회지 Vol.8 No.2

        Purpose: In men with prostate cancer, Androgen deprivation therapy shows a variety of well recognized metabolic alteration. But it is not known in Korean men with prostate cancer. To better characterize the metabolic effects of androgen deprivation therapy in Korean men, we evaluated the changes in fat thickness, bone mineral density (BMD), body mass index (BMI), and levels of hemoglobin (Hb) and cholesterol. Materials and Methods: From December 2002 to December 2008, 148 Korean men treated with leuprolide depot and bicalutamide for prostate cancer and 100 healthy subjects were investigated included change from baseline to month 12 in fat thickness, bone mineral density (BMD), body mass index (BMI), and levels of hemoglobin (Hb) and cholesterol. Fat thickness was estimated from subcutaneous fat thickness at T10 level through CT or MRI image. We also compared them with data from healthy subjects. Results: The mean fat thickness was significantly increased by 22.9% from baseline (16.6mm) to month 12 (20.4mm) in men with prostate cancer (p<0.001). The BMD was significantly decreased by 4.2% from 0.95 to 0.91 (p<0.001). The BMI was significantly increased by 4.8% from 23.0kg/m² to 24.1kg/m² 43 (p<0.001). The hemoglobin level was significantly decreased. In contrast, the cholesterol levels did not change significantly. The patients with prostate cancer had significant changes in fat thickness, BMD, and BMI, compared with healthy subjects (p<0.005, respectively). But there are no significant changes in hemoglobin and cholesterol levels. Conclusions: Our results show that Korean men with prostate cancer have increased abdominal subcutaneous fat and BMI and have decreased BMD during androgen deprivation therapy. These increases the risk of bone fracture and obesity related complication. Therefore, BMD will be checked periodically and carry out exercise program to prevention obesity during androgen deprivation therapy.

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