Correlations Between Fasciology and Yin Yang Doctrine

Hui Tao,Mei-chun Yu,Hui-ying Yang,Rong-mei Qu,Chun Yang,Xin Zhou,Yu Bai,Jing-peng Wu,Jun Wang,Ou Sha,Lin Yuan 사단법인약침학회 2011 Journal of Acupuncture & Meridian Studies Vol.4 No.2

The aim of this study is to explore the correlations between fasciology and yin yang doctrine. Professor Yuan developed fasciology by three-dimensional reconstruction of connective tissue (fascia) in the trunk and limbs of the human body and tracing back to tissue origins in light of biological evolution and developmental biology. Fasciology states that the human body can be divided into two systems: the supporting-storing system and the functional system. This article elaborates on the roles of the two systems and their mutual relationship. The two systems are used to analyze the yin,the yang, and their relationship. The two systems are promoted but also restricted in different contexts. The supporting-storing system is formed by undifferentiated connective tissue and provides undifferentiated cells and nutrients for differentiated cells of the functional system. Thus, the supporting-storing system could be classified as quiet, similar to yin. The functional system continuously maintains the various functional activities of the human body. Thus, the functional system could be classified as active, similar to yang. In interpreting the yin yang doctrine from the point of view of fasciology, yin can be compared with the supporting-storing system and yang can be compared with the functional system.

Thyroid-Associated Orbitopathy: Evaluating Microstructural Changes of Extraocular Muscles and Optic Nerves Using Readout-Segmented Echo-Planar Imaging-Based Diffusion Tensor Imaging

Huan-Huan Chen,Hao Hu,Wen Chen,Dai Cui,Xiao-Quan Xu,Fei-Yun Wu,Tao Yang 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.3

Objective: We aimed to investigate the ability of readout-segmented echo-planar imaging (rs-EPI)-based diffusion tensor imaging (DTI) in assessing the microstructural change of extraocular muscles (EOMs) and optic nerves in patients with thyroidassociated orbitopathy (TAO) as well as in evaluating disease activity. Materials and Methods: We enrolled 35 TAO patients and 22 healthy controls (HCs) who underwent pre-treatment rs-EPIbased DTI. Mean, axial, and radial diffusivity (MD, AD, and RD) and fractional anisotropy (FA) of the medial and lateral EOMs and optic nerve for each orbit were calculated and compared between TAO and HC groups and between active and inactive TAO groups. Factors such as age, sex, disease duration, mediation, and smoking history between groups were also compared. Logistic regression analysis was used to evaluate the predictive value of significant variables for disease activity. Results: Disease duration was significantly shorter in active TAOs than in inactive ones (p < 0.001). TAO patients showed significantly lower FA and higher MD, AD, and RD than HCs for both medial and lateral EOMs (p < 0.001), but not the AD value of lateral EOMs (p = 0.619). Active patients had significantly higher FA, MD, and AD than inactive patients for medial EOMs (p < 0.005), whereas only FA differed significantly in the lateral EOMs (p = 0.018). The MD, AD, and RD of optic nerves were significantly lower in TAO patients than HCs (p < 0.05), except for FA (p = 0.129). Multivariate analysis showed that the MD of medial EOMs and disease duration were significant predictors for disease activity. The combination of these two parameters showed optimal diagnostic efficiency for disease activity (area under the curve, 0.855; sensitivity, 68.4%; specificity, 96.9%). Conclusion: rs-EPI-based DTI is promising in assessing microstructural changes of EOMs and optic nerves and can help to indicate the disease activity of TAO, especially through the MD of medial EOMs.

Reliability Analysis and Prediction for Product Design Based on Feature Similarity

Tao Yang,Yu Yang,Yao Jiao 보안공학연구지원센터 2014 International Journal of Database Theory and Appli Vol.7 No.5

During product design phase, aiming at the problem of lacking reliability data, lower of product reliability, feature similarity-based new product design reliability analysis and prediction model were proposed. Putting the new product features as an evaluation objectives, an approach named Technique for Order Preference by Similarity to Ideal Solution(TOPSIS) was established firstly for selecting similar features products; Then, in order to realize the reliability analysis relational mapping with the new product design, the failure structure of the similar features products was quantified and the product failure structure matrix (FSM) was established, respectively; Afterwards, the Group Decision Making Method (GDMM) was presented for determining the improvement factor of the similar features products failure causes, on that basis, the new product features failure structure was generated to predict the reliability of new designing products. Finally, feasibility and effectiveness of the model were verified through an example of new Smart Mobile Phone product design.

Service life prediction of chloride-corrosive concrete under fatigue load

Yang, Tao,Guan, Bowen,Liu, Guoqiang,Li, Jing,Pan, Yuanyuan,Jia, Yanshun,Zhao, Yongli Techno-Press 2019 Advances in concrete construction Vol.8 No.1

Chloride corrosion has become the main factor of reducing the service life of reinforced concrete structures. The object of this paper is to propose a theoretical model that predicts the service life of chloride-corrosive concrete under fatigue load. In the process of modeling, the concrete is divided into two parts, microcrack and matrix. Taking the variation of mcirocrack area caused by fatigue load into account, an equation of chloride diffusion coefficient under fatigue load is established, and then the predictive model is developed based on Fick's second law. This model has an analytic solution and is reasonable in comparison to previous studies. Finally, some factors (chloride diffusion coefficient, surface chloride concentration and fatigue parameter) are analyzed to further investigate this model. The results indicate: the time to pit-to-crack transition and time to crack growth should not be neglected when predicting service life of concrete in strong corrosive condition; the type of fatigue loads also has a great impact on lifetime of concrete. In generally, this model is convenient to predict service life of chloride-corrosive concrete with different water to cement ratio, under different corrosive condition and under different types of fatigue load.

Liposome Formulation of Paclitaxel with Enhanced Solubility and Stability

Yang, Tao,Cui, Fu-De,Choi, Min-Koo,Lin, Hongxia,Chung, Suk-Jae,Shim, Chang-Koo,Kim, Dae-Duk Informa Healthcare 2007 DRUG DELIVERY Vol.14 No.5

<P> Despite its strong antitumor activity, paclitaxel (Taxol®) has limited clinical applications due to its low aqueous solubility and hypersensitivity caused by Cremophor® EL and ethanol which is the vehicle used in the current commercial product. In an attempt to develop a pharmaceutically acceptable formulation that could replace Taxol®, a paclitaxel incorporated liposome has been constructed to improve solubility and physicochemical stability. The effect of various components of the liposome, including cholesterol and lipid, on the solubility and entrapment efficiency (EE) of paclitaxel was systematically investigated. The results showed that 5% (v/v) of polyethylene glycol 400 in the hydration medium of liposome significantly increased the solubility (up to 3.39 mg/mL) as well as the EE and the paclitaxel content in the liposome formulation composed of 10% (w/v) of S100PC with cholesterol (cholesterol-to-lipid molar ratio = 10:90). When sucrose (sugar-to-lipid molar ratio = 2.3) was added as a lyoprotectant during the freeze-drying of the liposome, physicochemical stability of liposome was significantly improved. Moreover, the cytotoxicity of the final liposome formulation against MDA-MB-231 human breast cancer cell line was not significantly different from that of Taxol®. The enhanced aqueous solubility as well as the physicochemical stability of paclitaxel in the liposome formulation developed in this study could be a safer and effective alternative to the Cremophor® EL and ethanol formulation.</P>

High performance KNN-based single crystal thick film for ultrasound application

Tao Zhang,Jun Ou-Yang,Xiaofei Yang,Wei Wei,Benpeng Zhu 대한금속·재료학회 2019 ELECTRONIC MATERIALS LETTERS Vol.15 No.1

Using a novel lapping technology, the achievement of approximately 28 μm (K 0.45 Na 0.55 ) 0.96 Li 0.04 NbO 3 (abbreviated asKNLN) single crystal thick fi lm with <001> orientation has been realized. This kind of thick fi lm exhibited excellent electricalperformance: a superior piezoelectric constant (~ 490 pm/V) and an outstanding electromechanical coupling coeffi cient(k t ~ 0.55). Based on the obtained KNLN single crystal thick fi lm, a tiny side-looking 82 MHz ultrasound transducer witha bandwidth of 57.3% at − 6 dB has been successfully fabricated. Most importantly, 80 MHz intravascular ultrasound andphotoacoustic images of the healthy rabbit aorta have been presented. All these promising results indicate that KNN-basedsingle crystal thick fi lm is a good environmental protection candidate for high frequency (~ 80 MHz) ultrasound applications.

Modeling of Chloride Ion Diffusion in Concrete under Fatigue Loading

Tao Yang,Bowen Guan,Guoqiang Liu,Yanshun Jia 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.1

It is common for reinforced concrete in the saline region to bear fatigue loading and chloride induced corrosion, which has become one of the main causes of structural failure of reinforced concrete. The objective of this paper is to investigate the characteristics of chloride ion transport in concrete under fatigue loading. A new theoretical model describing the chloride ion transport in saturated concrete under fatigue loading is proposed. In this model, the concrete is divided into two parts, matrix and microcrack, to characterize the chloride diffusion coefficient of concrete based on crack area. The influence of fatigue damage on the microcrack area of concrete is quantitatively analyzed and the relationship between fatigue loading and chloride diffusion coefficient is established. Then, based on Fick’s second law, the model is proposed and solved by analytical solution. Some experiments are conducted to verify the proposed model and the simulated and measured results are in good agreement with each other. Finally, the characteristics of chloride ion transport under different influencing factors are analyzed using the proposed model.

Icariside II Promotes the Differentiation of Adipose Tissue-Derived Stem Cells to Schwann Cells to Preserve Erectile Function after Cavernous Nerve Injury

Tao Zheng,Tian-biao Zhang,Chao-liang Wang,Wei-xing Zhang,Dong-hui Jia,Fan Yang,Yang-yang Sun,Xiao-ju Ding,Rui Wang 한국분자세포생물학회 2018 Molecules and cells Vol.41 No.6

Icariside II (ICA II) is used in erectile dysfunction treatment. Adipose tissue-derived stem cells (ADSCs) are efficient at improving erectile function. This study aimed to explore the action mechanism of ADSCs in improving erectile function. ADSCs were isolated from the adipose tissues of rats. Cell proliferation was determined using the Cell Counting Kit-8 (CCK-8) assay. The expressions of mRNA and protein were determined separately through qRT-PCR and western blot. The endogenous expressions of related genes were regulated using recombinant plasmids and cell transfection. A Dual-Luciferase Reporter Assay was performed to determine the interaction between miR-34a and STAT3. Rat models with bilateral cavernous nerve injuries (BCNIs) were used to assess erectile function through the detection of mean arterial pressure (MAP) and intracavernosal pressure (ICP). ICA II promoted ADSCs’ proliferation and differentiation to Schwann cells (SCs) through the inhibition of miR-34a. Suppressed miR-34a promoted the differentiation of ADSCs to SCs by up-regulating STAT3. ICA II promoted the differentiation of ADSCs to SCs through the miR-34a/STAT3 pathway. The combination of ICA II and ADSCs preserved the erectile function of the BCNI model rats. ADSCs treated with ICA II markedly preserved the erectile function of the BCNI model rats, which was reversed through miR-34a overexpression. ICA II pro-motes the differentiation of ADSCs to SCs through the miR-34a/STAT3 pathway, contributing to erectile function preservation after the occurrence of a cavernous nerve injury.

A Study on the Formation and Mechanism of Zhengdong New District in Zhengzhou City

Yang, Jun-Tao,Baek, Seung-Man 대한건축학회지회연합회 2019 대한건축학회연합논문집 Vol.21 No.1

As a completely new metropolitan area, Zhengdong New District ecological space has experienced a complete formation process of "planning - construction", the planning scheme also experienced abandon and regression of initial planning concept, which leads to a certain complexity. This paper combed the formation process of the urban spatial in Zhengdong new district, summarized the important factors that affect the urban space change through the analysis of the urban space characteristics of different versions of the plan, and put forward the mechanism of urban space formation at the level of planning management.

Improving MapReduce Performance by Data Prefetching in Heterogeneous or Shared Environments

Tao Gu,Chuang Zuo,Qun Liao,Yulu Yang,Tao Li 보안공학연구지원센터(IJGDC) 2013 International Journal of Grid and Distributed Comp Vol.6 No.5