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      • 近視性 屈折異常의 疫學的 硏究

        劉世煥,廉容泰 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.1

        The distribution of ametropia whether refractive or axial in communities is variable according to factors such as ethnicon, age, living environment, and working begavior among others. Among young adults in Korea whose eves are fully matured most ametropia results form myopic refractive errors. It is well known that the prevalence of myopia among college students in Korea is very high, more than 60%. Nevertheless, community based epidemiological research on the causalities of myopia has: not been adequately performed to provide preventive or control measures for myopia for the young in Korea. In view of this, the author attempted an epidemiological study on myopia using the distribution of personal characteristics, and analyzing these factors on a total of 8,555(4,006 in 1981 and 4,549 in 1982) newly enrolled college students of Korea University The summarized results were as follows: 1. A total sample of 115 among 3,337 ametropic cases discovered during screening by visual acuity examination were selected for confirmation by objective refraction tests. One hundred percent of these were discovered to be of the myopic type. Statistical analysis of visual acuity and refraction revealed: R=-3.172+3.407V, r=-0.781, p<0.001 V=0.748+0.179R, r=-0.781, p<0.001 Using simple linear regression; and log(-R)=0.543-1.050V, R^(2)=0.673, F=419.478, p<0.001 logV=-0.042+0.629R, R^(2)=0.760, f=588.559, P<0.001 using logarithmic transformation of exponential curve linear regression, where V= visual acuity, and R=refraction in diopter. 2. The prevalence of ametropia was 65% in 1981 and 73% in 1982. Most of the ametropic cases were predicted to be the myopic type of refractive errors. No significant difference in prevalence by sex was found. However, the rates among males raised in urban areas, and among high economic females found to be significantly higher than other groups. 3. Factors related to causalities of myopia were analysed in terms of work credit, reading behavior, heredity, and food habits as shown in the followings; (1) The correlation between the variables of visual acuity and score on college entrance examinations was V=-0.01S+1.52, r=-0.14, p<0.001(where S=score) Showing a low interpretation capacity but very high reliability. (2) Average distance between the eyes and a book while reading was significantly shorter in myopia than the emetropia group. Distance in the majority of myopia cases were less than 25cm. (3) Attack rate of myopia of siblings born from myopic parents(one or both eyes) was found to be significantly higher(doubled) than that from emetropic parents. This provides substantial evidence that heredity plays an important role in revealing myopia. (4) There were more vegetarians and persons with seriously unbalanced diets in the myopia group. However, rates by visual acuity were too low to be tested for significance. 4. Clinical findings included the relationship between the site of major eye and myopic eye, data on the correction of visual acuity, and onset on visual disturbances. (1) In the majority of the emetropic group the major eye was the right eye, while in persons whose right eyes were myopic the majority had left eyes as the major ones. Similarly, in case where the left eye was myopic the right eye tended to be the major eye. In cases where both eyes were myopic, the pattern followed the emetropic group in that the majority had the right eyes as the major eye. (2) The more severe the myopic status was, the higher the rate of wearing glasses was. About 50% of glasses wearers got their glasses from opticians without an ophthalmologist’s prescription. (3) The onset of visual disturbance in the majority(47%) of myopic cases was during highschool.

      • 형광검출 역상 액체크로마토그래피에 의한 Histamine의 정량

        유희춘,김형룡,김상현,김대기,이영미,김형민,안년형,신태용 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

        Histamine을 정확하고 신속하게 정량하기 위해 9.Fiuorenylmethyl chloroformate를 형광유도체화제로 하여 역상 HPLC법으로 정량하였다. 히스타민을 형광유도체화할 때 반응액의 pH, 반응시간, 형광유도체화제의 농도 등 최적 반응 조건을 검토하였다. 이 방법으로 히스타민을 분석한 결과 0.1~0.5ug/ml의 농도범위에서 상관계수가 0.922인 양호한 직선성을 나타내었으며 검출한계는 0.01??/ml였다. A rapid and simple method for the determination of histamine by reverse-phase high performance liquid chromatography with fluorescence detection was established. 9-Fluorenylmethyl chloroformate(FMOC) was used as fluorescent derivative reagent. The optimum conditions for the derivatiation such as pH, reaction time and he concentration of FMOC were investigated. Linearity of calibration curve was obtained between 0.1ug/ml/and 0.5ug/ml(r=0.922) and the limit of detection was 0.01ug/ml.

      • 농촌 집단검진시 재검수진 행위이행에 관한 연구 : Papanicolau 세포진 검사를 중심으로 In Case of Papanicolau Smear

        유지소,염용태 고려대학교 의과대학 1992 고려대 의대 잡지 Vol.29 No.3

        Among females in Korea, cervical cancer is one of the most common malignant tumors Exfoliative cytology is a highly sensitive and specific test with low expense for early detection of cervical cancer and its precursors. This is why the test is widely used for screening purpose. However, in case of screening, the validity is lowered, and so it should be compensated for by recheck to confirm. From the viewpoints above, the Korea University performed prescheduled cervical cancer screening tests from 1987 to June 1990 for a total of 1,761 women living in Yeoju Gun, Kyong Kee Province where K.U. Hospital is located. This research includes the results of the tests and the discussion on the participation in second stage examination for the confirmation purpose. This can be summarized as follows. 1. Cytological result of the Papanicolau smear revealed 0.7% of C.Ⅲ and 0.1% of C.Ⅳ category. And 42.2% of cases showed some signs of gynecological inflammation which were subjected to recheck. 2. A total of 209 (27.9%) among 750 inflammatory category participated in the second stage confirmation test. 3. It was confirmed that geographical accessibility in terms of distance from hospital to residential area could not afford to influence the rate of participating in confirmation test. 4. As the result of stepwise multiple regression analysis of the subjects to be rechecked. accumulative R square of symptom level. occupation, economic status, age and numbers of children was 46.8% in relation to the participation in the second stage examination for confirmation purpose.

      • SCOPUSKCI등재

        이담자균 효모 Rhodosporidium toruloides에서 Rhodotorucine A에 의한 막단백질 인산화의 저해와 Trigger Peptidase의 관련성

        정영기,이태호,류병호 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

        이담자 효모균 Rhodosporidium toruloides 접합형 a 세포의 막단백질 가용화 분획을 비변성 전기영동에 의하여 인산화 한 결과 인산화 되는 단백질을 발견하였다. 이 단백질의 인산화는 Rhodotorucine A (Rh. A)에 의하여 저해되었다. 본 인산화 단백질에는 trigger-peptidase (TPase)가 존재하고 있는 것을 확인 하였으며, TPase inhibitor(antipain)를 반응액에 첨가할 경우 Rh. A에 의한 인산화 저해작용은 나타나지 않았다. 그리고, Rh. A를 trypsin으로 분해한 산물을 반응액에 첨가했을 경우 인산화 저해현상이 있는 것으로 보아, 인산화의 저해반응에는 TPase가 중요한 작용을 하는 것이 확인되었다. [γ-^32P]ATP was used to test phosphorylation of membrane proteins of mating type a cells of heterobasidiomycetous yeast Rhodosporidium toruloides separated by non-denaturing electrophoresis. The phosphoprotein was observed in the membrane proteins. The phosphorylation was inhibited by the pheromone rhodotorucine A (Rh. A) secreted by mating type A of the yeast. Rh. A didn't inhibit the phosphorylation in the presence of a trigger peptidase (TPase) inhibitor, antipain. Partially digested Rh. A by trypsin maintained the phosphorylation inhibitory activity. These results show that TPase activity plays an important role in the transduction of pheromone signal in the yeast.

      • 단면의 성질을 적용한 크기와 회전 변화에 불변인 영상 검사 시스템

        이용중,김태원,김기대,류재엽 한국공작기계학회 2001 한국공작기계학회 춘계학술대회논문집 Vol.2001 No.-

        The purpose of this paper is to develop image inspection system endows an automatic operating and measuring that the moment values are invariant with respect to variable object size and rotation. In this paper, using these moment feature vector with Hu's 7 invariant moment is also given. The charasteristics of section which is applied in the mechanics used moment descriptor of invariant moment detection algorithm for image inspection system. Corresponding rates between 94% and 96% have been achived for all object tested.

      • F.A. Process에 의한 下水處理에 관한 硏究

        姜龍太,柳在益,許宗文 東亞大學校 海洋資源硏究所 1989 硏究論文集 Vol.2 No.1

        The purposes of this researches were to evaluate the effects of an advanced processes supplemented Conventional Activated Sludge Process and to invent the economical advanced process combined activated sludge process with FAC(Flocculation-Aeration-Clarification). Raw water used was synthetic wastewater. The primary treatment using the PAC process was effective in treating the wastewater with lower concentration. F.A process showed the removal rate of more than 90 percent without regard to variences of influent concentration.

      • KCI등재

        DBD 반응기에서 플라즈마 방전형태에 따른 PFC_(s) 가스의 분해 특성

        김관태,김용호,차민석,송영훈,김석준,류정인 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.5

        Perfluorocompounds(PFC_(s)), such as tetrafluoromethane (CF₄) and hexafluoroethane (C₂F_(6)), have been widely used as plasma etching and chemical vapor deposition (CVD) gases for semiconductor manufacturing processes. Since these PFC_(s) are known to cause a greenhouse effect intensively, there has been a growing interest in reducing PFC_(s) emissions. Among various CF₄ decomposing techniques, a dielectric barrier discharge (DBD) is considered as one of a promising candidate because it has been successfully used for generating ozone (O₃) and decomposing nitrogen oxide (NO). Firstly, optimal concentration of oxygen for CF₄ decomposition was found to figure out how many primary and secondary reactions are associated with DBD process. Secondary, to find effective discharge method for CF₄ decomposition, a streamer and a glow mode in DBD are experimentally compared, which includes (ⅰ) coaxialcylinder DBD, (ⅱ) DBD reactor packed with glass beads. and (ⅲ) a glow mode operation with a helium gas. The test results showed that optimal concentration of oxygen was ranged 500 ppm~1% for treating 500 ppm of CF₄ and helium glow discharge was the most efficient one to decompose CF₄.

      • 해양미생물로부터 카로테노이드 색소의 생산을 위한 최적조건

        정영기,박정욱,주우홍,류병호,정명주,김태수 동의대학교 기초과학연구소 2000 基礎科學硏究論文集 Vol.10 No.1

        The optimal medium composition for the production of carotenoid pigment from Haloarcular sp. EH-1 as a dietary for fishes were 1.0% sucrose, 1.0% yeast extract, 25% sodium chloride, 0.3% sodium citrate, 0.2% potassium chloride, 2.0% magnesium sulphate, 0.002% ferric sulphate(pH7.0). The incubation temperate, aeration rate and agitation speed were 40℃, 100ml medium/500ml vol. shaking flask, and 180 rpm/min. The carotenoid pigment production was highest after 5 days of incubation with the light.

      • 地方職化 以後 農村指導事業의 推進 方向

        황대용,류진춘,하태일 慶北大學校農業科學技術硏究所 1998 慶北大農學誌 Vol.16 No.-

        As a result of the execution of the import liberalization and local autonomy with WTO system launching, centralized rural extension service converted to localized rural extension service. This advent of globalization and localization era affects our over all agricultural condition, moreover the duty and role of rural extension organization which take complete of rural extension, is compelled to diversified and specified technology. In this study, first we will investigate the change of agricultural, rural community, and local rural extension service in globalization and localization era. Second we will analyze the confronted problems of local rural extension service. With this study's outcome for basis, we will present new role and direction of local rural extension service which can contribute to local agricultural development.

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