위험평가(Risk Assessment)에 의한 업종별 위험(Risk)의 구분

박동욱,박덕묵,정광수,윤충식,김태형,노영만,이경남,이송권,김현욱 한국산업위생학회 2003 한국산업보건학회지 Vol.13 No.2

A total of 514 workplaces in 17 industries were inbestigated through walk-through survey. These industries were all small companies with less than five workers and didn't have work environmental measurement data. These industries were ranked by risk that was evaluated by combination of toxicity and possibility of exposure to chemical hazardous agents produced at operations of industry. Risk Index(RI) was qualitatively combined by the combination between hazard and potential of exposure to chemical hazardous agents. Industries that were regarded as having the highest risk were wood and products of wood, chemicals and chemical products, basic metals, other vehicles, trailers and semi-trailers, and fumiture manufacturing. These industries were found to have operations with higher risk than other industries. This study found that more attentions should be paid to these industries with that more attentions should be paid to these industries with high risk.

악관절장애진단에 있어서 동시다층개별화측방단층촬영의 진단효과

이우식,박태원 大韓口腔顎顔面 放射線學會 1991 Imaging Science in Dentistry Vol.21 No.2

This study was designed to evaluate the diagnostic effect of the simulatenous multifilm individualized lateral tomography in the diagnosis of the temporomandibular disorders. The subjects consisted of 29 patients with symptoms of the temporomandibular disorders. The panoramic view, oblique lateral transcranial radiograph (OLTC) (Hirozontal angulation 0°, Vertical angulation 29°), submentovertex view, and simultaneous multifilm individualized lateral tomographs (SMFI) in centric occlusion (2.5mm thickness difference, 5 layers) were taken for the patients. This study compared the findings from each radiographs in the determining of mandibular condylar position with dual linear measurement of the subjective closest posterior and subjective closest anterior interarticular space and in the determining of bony changes on the studied 30 temporomandibular joints (TMJ) with symptoms of the temporomandibular disorders. The results were as follows: 1. The distribution of condylar position of OLTC and 5 layers of SMFI depended on the radiographs(p<0.05). The condylar position and the distribution of condylar position of OLTC were more similar to lateral sections of the SMFI than mesial sections, and in the distribution of the condylar position of SMFI, the more lateral sections of SMFI, the more concentric positions. 2. There were 10 cases in which all layers showed the same condylar position as that of OLTC. There were 3 cases in which no layers showed the same condylar position as that of OLTC. 3. In the SMFI of 30 Temporomandibular joints studied, there is 13 cases in which all five layers represented the same condylar position in the same TMJ and 11 cases in which 4 layers represented the same condylar position in the same TMJ and 6 cases in which 3 layers represented the same condylar position in the same TMJ. So at least 3 layers of SMFI represented same condylar position in the same TMJ. 4. The bony changes were not detected in conventional radiographs on the temporomandibular joint and the bony changes were not detected in simultaneous multifilm individualized lateral tomographs. The bony changes were detected in conventional radiographs on the temporomandibular joint and the bony changes were detected in simultaneous multifilm individualized lateral tomographs. SMFI provided a meams for a three dimensional visualization of the shape, the position and the extent of bony changes of TMJ.

하악에 발생된 법랑모 섬유육종

최갑식,이은숙,박태원,최미 大韓口腔顎顔面 放射線學會 1993 Imaging Science in Dentistry Vol.23 No.2

The ameloblastic fibrosarcoma is the malignant counterpart of the ameloblastic fibrosarcoma in which the mesenchymal element has become malignant. Clinically it frequently occurs in the 3rd and 4th decades, and more frequent in the mandible than in the maxilla. Radiographic features are apparent multiocular radiolucency with ill-defined border. The authors experienced two cases of ameloblastic fibrosarcoma of the mandible in a 26-year-old male and a 48-year-old female patients who suffered from pain and swelling on the affected area. And we discussed the clinical, radiological and histopathological features of this disease with a brief review of the literatures.

화농성 슬관절염이 동반된 수막구균성 수막염 1예

김태연,유진홍,박성환,김연식,임상현,신완식,강문원,정창훈,최문구,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.2

저자들은 최근 화농성 슬관절염과 병발한 수막구균성 수막염 1예를 체험하였고, 이는 국내에서 아직 보고되지 않은 드문 예로 사료되어 문헌고찰과 함께 보고하는 바이다. We recently experienced a case of meningococcal meningitis associated with pyogenic arthritis in a 37-year old male patient. Pyogenic arthritis developed in right knee joint during treatment for meningococcal meningitis. He was treated successfully by appropriate antibiotics and arthroscopic irrigation. To our knowledge, such a rare case has not ever been reported in Korea, Hence we report this case with a review of related literatures.

극저준위 감마선 분광시스템의 백그라운드 저감화를 위한 중성자 차폐체 설계

김태욱,박종묵,박종길,신상운,전재식 대한방사선 방어학회 2001 방사선방어학회지 Vol.26 No.2

극저준위 방사능측정시스템의 백그라운드에 영향을 주는 중성자를 차폐하기 위한 차폐체를 설계하였다. 중성자 차폐방법은 고 밀도 폴리에틸렌을 이용하여 고속중성자를 감속한 후 B4C를 이용하여 감속된 열중성자를 흡수하는 방법을 이용하였다. 몬테카를로 모사방법인 MCNP4B 코드를 이용하여 계산한 결과 고 밀도 폴리에틸렌의 두께가 10 cm 일 때 열중성자속이 최대가 되는 것으로 나타났으며 감속된 중성자의 흡수는 용제에 자연상태의 B4C 분말을 30 w% 섞을 경우 2 mm의 두께에서 94%의 중성자 흡수가 일어나는 것으로 나타났다. 또한 몬테카를로 모사를 통한 계산결과의 타당성 여부를 조사하기 위하여 중성자 차폐실험 장치를 제작하여 실험 결과와 비교하였으며, 비교 결과 실험값과 일치하는 것으로 나타났다 In order to shield the neutrons affecting the background of Low Level Gamma Ray Spectrometer, a neutron shielder was designed. The method used in this study for neutron shielding was the deceleration of fast neutrons by high density polyethylene(HDPE) and the absorption of those slowing-down neutrons by B4C. The calculation results of neutron interaction in HDPE using Monte Carlo simulation code MCNP4B showed that the thermal-neutron flux was maximum at 10 cm thickness of HDPE. The results also showed that 95% of the thermal neutrons were absorbed by 2 mm thickness of B4C absorber consisted of 30 w% B4C and 70 w% polymer. The results of the Monte Carlo calculation were in good agreement with the experimental value obtained by a neutron shielding apparatus designd for this purpose.

신경외과 중환자실에서 치료받은 환자들의 합병증 및 사망율에 대한 임상적 분석 : A Prospective Study of 200 Consecutive Patients

이성운,박상근,김태홍,권점대,신형식,김상진 인제대학교 1997 仁濟醫學 Vol.18 No.2

저자들은 본원 신경외과 중환자 관리의 개선을 위하여 1993년 2월부터 12월까지 중환자실에 입원하여 치료받은 환자 200명을 대상으로 합병증 및 사망율을 일정한 분석양식에 의하여 후향성 연구를 시행하였다. 전체 합병증 발생률은 16.5% 였으며, 환자의 의식 상태가 나쁘고 재원 기간이 길수록 빈도가 증가하였다. 합병증중에서 감염이 66.8%로 합병증 중 가장 많은 빈도를 보였으며, 감염 부위별로는 요도 감염(18.8%), 상처 감염(18.8%) 그리고 폐렴(16.9%) 순으로 많았다. 그외 합병증은 욕창(9.4%), 위장관 질환(7.5%), 피부 질환(7.5%) 순이었다. 사망자는 18명으로 전체 환자의 9%를 차지하였으며 그중 외상 환자가 11명(61%)으로 가장 많았다. 사망 원인은 패혈성 쇼크로 사망한 1명을 제외하고 나머지 모두는 두개강 내압 항진으로 중환자실에서 치료상 합병증에 의하여 사망한 것은 아니었다. 따라서 본 연구 결과 적합한 약물 요법, 적절한 인원 배치, 시설의 개선 및 종사자들에 대한 적극적인 교육 등을 통하여 중환자실에서의 환자 관리를 개선함으로써 합병증 및 사망율을 감소시킬 수 있을 것으로 사료된다. In order to improve the management outcome of patients in neurosurgical intensive care unit(NICU), the authors analyzed complications and mortality of 200 consecutive patients between February and December 1993. Complications were occurred in 33 patients (16.5%) among 200 patients who had been treated at NICU. Infection(66.8%) was the most common complication in our complication series and their detailed sites were urinary tract infection(18.8%), wound infection (18.8%) and pneumonia (16.9%). The motality rate was 9%. Increased intracranial pressure was the most common cause of death. Based on this study, the authors conclude that appropriate medical treatment, proper management and education for personnel and excellent equipments were key to prevention of complication and mortality.

Benzodiazepinone과 1,5-Benzodiazepine 유도체의 합성 연구

정대일,이용균,박유미,최태원,정일수,김인식,김윤영 東亞大學校 1997 東亞論叢 Vol.34 No.-

The reaction of o-phenylenediamine 5 with acrylic acid 11 in the presencce of P₂O5+H₃PO₄afforded benzodiazepinone 13 and pyridobenzodiazepinono 17. The reactions of o-phenylenediamine 5 with acrylic acid 11 in the presence of PPA or SiO₂afforded only benzodiazepinone 13. But the reaction of O-phenylenediamine 5 with acrylic acid 11 in the presence of acetonedicarboxylic acid 18 or acetonedicarboxylic acid 18 and PPA or acetonedicarboxylic acid 18 and SiO₂was respectively synthesized 2,4,4,-trimethyI-3H-5-hydro-1.5-benzodi-azepine 23 as new cyclic imine compound. We propose that formation of 2-(2`-imine)propyI-N-isopropylidene aniline proceed though 2-amino, N-isopropylidene aniline intermediate C and 2-(N-a-methylethyI) amino, N-isopropylidene aniline intermediate G. The reaction of o-phenylenediamine 5 with acetonedicarboxylic acid 18 in the presence of PPA or SiO₂or HCI gave 2,4,4-trimethyI-3H-5-hydro-1,5-benzodiazepine 23. Using acetone 19 instead of acetonedicarboxylic acid 18, the reaction of o-phenylenediamine 5 in the presence of PPA or SiO₂or acrylic acid 11 was synthesized 2,4,4-trimethyI-3H-5-hydro-1,5-benzodiazepine 23 as same product. And also the reaction of o-phenylenediamine 5 with acetone 19 and acrylic 11 in the presence of PPA or SiO₂was obtained 2,4,4-trimethyI-3H-5-hydro-1,5-benzodiazepine 23. In case of acetophenone 21 in stead of acceton 19, the reaction of o-phenylenediamine 5 in presence of PPA or SiO₂at 40~45℃ were obtained 2,4-diphenyI-4methyI-3H-5-hydro-1,5-benzodiazepine 24. The reaction of o-phenylenediamine 5 with crotonic acid 25 in the presence of PPA or P₂O5+H₃PO₄or SiO₂at 100~110℃ afforded respectively 4-methybenzodiazepinone 26 as 1:1 cycloadduct.

Ventriculosubgaleal shunt의 임상적 경험

남궁원철,박상근,김태홍,신형식,황용순,김상진 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.2

Object : Ventriculosubgaleal(VSG) shunt is considered to be useful and safe ventricluar diversion method for the patient for whom ventriculoperitoneal(VP) shunt cannot be carried out because of significant particulate debirs within the CSF, recent surgeries, or infections that were considered substantial enough to impair shunt function or to increase the risk of infection. To clarify the efficacy of VSG shunt for temporary ventricular decompression we analyzed our clinical trial cases. Patients and Methods : VSG shunt was carried out in 8 patient with acute hydrocephalus between February 2000 and June 2000. The causes of acute hydrocephalus were as follows: spontaneous intracerebral hemorrahage and intraventricular hemorrhage in four patients, spontaheous subarachnoid hemorrahge in three patients, tuberculous meningitis in one patient. With these 8 cases we compared pre-operative and post-operative clinical conditions and ventricular size in the brain CT scan. Results : Even though the ventricular size was not changed statistically there was significant clinical improvement between preoperative Glasgow coma scale(GCS)(7.25) and postoperative GCS(9.25). Six patients died as a result of causes unrelated to the VSG shunt. There were no VSG shunt infection. A permanent ventriculoperitoneal shunt surgery was needed in two patients. Conclusion : The VSG shunt is a simple and safe method of treatment for acute hydrocephalus instead of extraventricular drainage in the patients who cannot be underwent a permanent shunt immediately due to some reasons. Even though VSG shunt were free from infection, our preliminary clinical trials suggests that its efficacy seems to be doubtful. Further studies with lots of cases would be needed for its clinical application.

한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

백서 간재생중 H2B Histone 유전자 발현에 대한 Octamer Binding Transcription Factor의 역할

임규,방재웅,최두식,손미영,이영철,박청,김태동,김영래,박종일,윤완희,박승길,황병두 한국노화학회 2001 한국노화학회지 Vol.11 No.1