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      • KCI등재

        역전파 신경회로망을 이용한 가공조건에 따른 STD-11 절단면의 신뢰성 평가

        김선진,성백섭,조규재,김하식,반제삼 한국공작기계학회 2004 한국생산제조학회지 Vol.13 No.5

        The purpose of this study was to present the method to choose the optimum machining condition for the wire EDM. This was completed by examining the ever-changing quality of the material and by improving the function of the wire electric discharge machine. Precision metal mold products and the unmanned wire electric discharge machining system were used and then applied in industrial fields. This experiment uses the wire electric discharge machine with brass wire electrode of 0.25mm. To measure the precision of the machining surface, average values are obtained from 3 samples of measures of center-line average roughness by using a third dimension gauge and a stylus surface roughness gauge.

      • 농가용 저온저장고의 제어변수에 따른 성능평가

        김석우,김성만,현명택,최동호,고정삼,박영하 제주대학교 공과대학 첨단기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.2

        The low temperature storage method has been used to increase the value of agricultural products by reducing quality deterioration and controlling respiration rate. The respiration rate of agricultural products depends on several factors such as temperature, moisture, gas composition and microbe inside the storage room. Among that temperature is the most important factor, which affects respiration rate and causes severe damage. The results obtained from these experiments are that electric consumption is decreased as setting temperature is decreasing and temperature deviation is increasing. In the ventilation experiment, the case ventilated four times a day(every six hours a day) with ten minutes operation each time, was inspected require as much electric consumption as non-ventilation case.

      • 저장물의 적재방법에 따른 저온저장고의 열성능 분석

        김석우,김성만,현명택,최동호,고정삼,박영하 제주대학교 공과대학 첨단기술연구소 2001 尖端技術硏究所論文集 Vol.12 No.2

        The heat performance in a forced circulating cool storage room was numerically investigated. A commercial PHOENICS package was used to simulate 3-D airflow. For solving the governing equations a standard k-ε turbulent model was implemented to calculate steady state turbulent velocity and temperature distributions. The results show that the large air contacting area of products increases the storage quality, because the airflow between products helps to remove the heat from the products by convective heat transfer.

      • Streptozotocin-당뇨병 백서에서 당뇨병 이환기간에 따른 대동맥의 이완능 저하 및 Oxygen-Free Radical에 의한 이완능의 손상정도

        김정국,김신우,김수동,서예경,하승우,김보완,백운이,권삼,강승완 경북대학교 병원 1997 경북대학교병원의학연구소논문집 Vol.1 No.1

        목적: 당뇨병의 이환기간이 혈관의 내피세포 의존성 및 비의존성 이완능의 저하에 미치는 영향과 이환기간에 따라 oxygen-free radical(OFR)에 의한 동맥이완능의 손상정도에 차이가 있는지를 알아보고자 하였다. 방법: Streptozotocin(STZ)으로 당뇨병이 유도된 3 주 및 10주째의 백서군과 연령이 비슷한 정상 대조백서군의 적출 대동맥환을 norepinephrine으로 수축시킨 상태에서 내피세포 의존성 이완제인 acetylcholine(ACh) 및 비의존성 이완제인 nitroglycerine(NTG)에 대한 이완능을 즉정하여 비교 관찬하였다. 또한 xanthine과 xanthine oxidase의 혼합으로 생성된 H₂O₂에 대동맥환을 노출시킨뒤 역시 ACh과 NTG에 대한 이완능의 손상정도를 비교하였다. 결과: 3주및 10주째 당뇨병 백서의 대동맥환은 모두 대조군 백서의 대동맥환에 비해 ACh에 대한 이완능이 유의하게 감소하였으며 10주째 당뇨병 백서군에서의 ACh에대한 이완능의 저하는 3 주째 당뇨병 백서군에 비해 유의하게 심하였다.H₂O₂에 노출시킨 뒤 ACh에대한 이완능은 3주 및 10주 째 당뇨병 백서군에서 모두 대조군에 비해 유의하게 심한 손상을 보였으나 3주와 10주째 당뇨병 백서군 사이의 손상정도의 차이가 통계학적으로 유의하지는 않았다. 한편 3주 및 10주째 당뇨병 백서군 모두 NTH에 대한 대동맥환의 이완능은 대조 백서군과 별다른 차이가 없었으며 또 H₂O₂에 노출시킨 뒤에도 NTG에 대한 이완능의 손상은 관찰되지 않았다. 결론: STZ-당뇨병백서에서 대동맥의 이완능은 당뇨병에 이환된지 3 주째에 이미 ACh에 대한 내피세포 의존성 이완능이 선택적으로 저하되며 당뇨병의 이환기간이 길수록 이완능의 저하가 심하였고, OFR에 의한 동맥 이완능의 손상도 내피세포 의존성 이완능에만 선택적으로 나타나나 이환기간에 따라 OFR에 의한 이완능 손상정도에는 뚜렷한 차이가 없음을 시사하고 있다. Objectives: Diabetes mellitus produces histological evidence of endothelial as well as changes in vascular function in experimental animal. Oxygen free radicals interfere with of destroy endothelium-dependent relaxation in normal and diabetic blood vessels. The present study was investigated whether the duration of diabetic state can affect the severity of impairment in endothelium-dependent and/or independent relaxation and the sensitivity to oxygen free fadical (OFR)-induced damage in diabetic rat vasculature. Methods: The relaxative responses of aortic ring precontracted with norepinephrine in vitro to cumulative concentrations of acetylcholine (ACh) and nitroglycerine (NTG) were conducted in 3- and 10- week streptozotocin (STZ)-diabetic rats and agematched controls. After exposure to H₂O₂generated by mixing xanthine and xanthine oxidase, the degree of impairment in relaxative responses to ACh and NTG were also compared between 3- and 10-week diabetic rats. Results: The relaxative responses of aortic rings produced by cumulative concentrations of ACh were significantly lower in both 3- and 10-week diabetic rats than in the age-matched controls. The impairments of relaxative responses to ACh in 10-week diabetic rats were significantly greater than those in 3-week ones. After H₂O₂ exposure, the impairments of relaxative responses to ACh in 3- and 10-week diabetic aortas was also significantly greater than those in the control in the control ones. However, the severity of H₂O₂-induced damage in 10-week diabetic aortas was not significantly different than that in 3-week ones. In contrast, aortic rings of 3- and 10-week diabetic rats could still be fully relaxed by NTG, even after exposure to H₂O₂. Conclusion: These findings suggest that in SRZ-diabetic rat aortas selective impairment of endothelium-dependent relaxation to Ach can be found early even over a 3-week period after the induction of diabetes and the impairment may be greater in those with the longer duration of the diabetic state and that the impairment of the vascular relaxation by OFR is also selective to endothelium-dependent response but the sensitivity of OFR-induced damage may not be related to the duration of the diabetic state.

      • 간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

        조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

        Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

      • Antimicrobial and antioxidative effects of the synthetic peptide CP112 in the Scolopendra subspinipes mutilans

        Sang-hee Kim,Joon Ha Lee,In-Woo Kim,Eun-Young,Sung-Hee Nam,Mi-Young Ahn,Jae Sam Hwang 한국응용곤충학회 2013 한국응용곤충학회 학술대회논문집 Vol.2013 No.10

        Previously, we performed de novo RNA sequencing of Scolopendra subpinipes mutilans using high-throughput sequencing technology and identified several AMP candidates. Among them, a synthetic peptide (CP112) was designed based on the physicochemical properties of antimicrobial peptide such as length, charge, isoelectric point. Here, we have assessed the antimicrobial activities of CP112 against various microbes and the antioxidative effects. The results showed that CP112 had antimicrobial activities in radial diffusion assay and colony count assay. In addition, we found that CP112 bound to the surface of microorganisms via a specific interaction with lipoteichoic acid, lipopolysaccharide and peptidoglycan, which is one of bacteria cell wall components. Furthermore, CP112 has shown significant DPPH radical scavenging activity. Taken together, the results would be provided the basis for developing of peptide antibiotics and antioxidants.

      • Poster Session:PS 1090;Gastroenterology (Gastrointestinal Tract):Primary Malt Lymphoma of Colon; Differential Diagnosis of Colonic Metastasis of Rapidly Growing Poorly Differentiated Advanced Gastric Adenocarcinoma

        ( Sung Sam Ha ),( Hyun Soo Kim ),( Jae Woo Kim ),( Hong Jun Park ),( Hee Man Kim ),( Kyoung Joo Lee ),( Hyun Sik Kim ),( Yong Seok Kang ),( Yoo Li Lim ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Introduction: Primary colorectal lymphoma is rare, less than 1% of colorectal malignancies and known about 1. 4% of non-hodgekin lymphoma. Also colonic metastases from gastric adenocarcinoma is rare. We describe a rare case of Differential diagnosis of primary MALT lymphoma of the colon with colonic metastasis of advanced gastric adenocarcinoma. Case: A 81 year-old female patient presented with advanced gastric cancer (AGC) from local clinic. She had no evidence of cancer at esophagogastroduodenoscopy (EGD) 2 years ago. She had been treated for hypertension and diabetes. Physical examination revealed rectal shelf postive. Her routine blood investigations including tumor markers(i. e CEA, CA19-9) were normal. On EGD, AGC of Borrmann type 3 on posterior wall of upper body were revealed and colonoscopy showed multiple subepithelial masses of cecum, ascending colon and rectum. Computer tomography(CT) and positron emission tomography( PET) showed fiurodeoxyglucose(FDG)-uptakes of stomach, cecum, rectum and adjacent bladder and vagina. Histologically, poorly differentiated tubular adenocarcinoma of stomach was reported, but the colonic biopsy revealed many small to medium sized lymphoid cells and diagnosed MALT lymphoma, featuring CD20 positive and cyclin D1 negative. The patient refused both treatment and follow-up because of her age. Discussion: MALT lymphoma of colon and colonic meatastasis of AGC are very rare. The radiologic differential diagnosis of lymphomatous polyposis of colon is diffi cult especially in rapidly progressive AGC. Also colonic lymphoma taking the form of polyposis is very rare and is almost mantle cell lymphoma, but this case reported MALT lymphoma. In rapidly progressive AGC with rectal shelf positive, the subepithelial tumors of cecum, favoring localization of colorectal lymphoma and multiple nodularity on rectum should be distinguished peritoneal metastasis and other malignancies. This case shows that we should keep primary colorectal lymphoma in mind.

      • KCI등재

        복강경 담낭절제술 10년 경과 후 외과용 클립에 의해 발생한 총담관결석

        하성삼 ( Sung Sam Ha ),임유리 ( Yoo Ri Lim ),이지현 ( Ji Hyeon Lee ),심정한 ( Jeong Han Sim ),유진세 ( Jin Sae Yoo ),이경주 ( Kyong Joo Lee ),김동현 ( Dong Hyun Kim ),김재우 ( Jae Woo Kim ) 대한췌장담도학회 2015 대한췌담도학회지 Vol.20 No.1

        Rarely, surgical clips can migrate into the biliary tract after laparoscopic cholecystectomy and work as a nidus for biliary stone formation. We report a case of the development of a common bile duct (CBD) stone induced by surgical clip in a 57-yearold man who underwent laparoscopic cholecystectomy 10 years ago. On computed tomography, a CBD stone with a metallic material was found, and endoscopic retrograde cholangiopancreatography (ERCP) revealed a CBD stone including a metallic clip. The stone was removed completely by ERCP, and the surgical clip was found along with the stone.

      • 합성 Mellin Radial Harmonic필터를 이용한 위치 및 크기불변 물체인식

        하영호,신현삼,김성용,김수중 경북대학교 전자기술연구소 1990 電子技術硏究誌 Vol.11 No.1

        The proposed composite MRH(Mellin radial harmonic) filter, which is derived from a single MRH with shift- and scale- invariance. even recognizes the objects of scaled and/or similar shapes. The proposed composite MRH filter also can recognize inputs with the additive with nonzero mean gaussian noises by constant correlation threshold. Since the composite MRH filter is realized by CGH(computer- generated- hologram) which has amplitude and phase informations of the object. The light efficiency of this CGH filter is as high as the Wai-Hon-Lee CGH filter, which has only phase informations of the object.

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