신장이식 환자에서 HCMV 항원혈증 검사의 임상적 유용성

김탁,성흥섭,박관태,김송철,김성한,최상호,김양수,우준희,박수길,한덕종,이상오 대한감염학회 2009 감염과 화학요법 Vol.41 No.2

Background : This study was performed to determine the cut-off value and the predictability of symptomatic human cytomegalovirus (HCMV) infection according to the peak value of HCMV antigenemia assay in kidney transplant recipients. Materials and Methods : We reviewed the results of HCMV antigenemia assay (Chemicon, CA, USA) in patients who received kidney transplantation at our institution from May 2003 through May 2008, and investigated the existence and the type of HCMV infection by the medical record review. Patients who underwent the test only once during the episode or those who received ganciclovir for more than 48hrs before the test were excluded. The receiver-operator characteristic curve was drawn and the point showing maximum likelihood ratio (LR) was chosen as the cut-off value of symptomatic HCMV infection. Results : A total of 689 episodes were screened and 134 episodes were enrolled. Thirty-three (24.6%) episodes were symptomatic HCMV infection, 23 (17.2%) episodes were associated with HCMV syndrome, and 10 (7.5%) episodes were tissue-invasive diseases. The maximum LR was 7.5 (95% confidence interval, 4.014.2) and the cut-off value was 29.5 cells/200,000 WBC. The sensitivity, specificity, Positive predictive value, and negative predictive value were 66.7%, 91.1%, 71.0%, and 89.3%, respectively. Conclusions : The cut-off value of symptomatic HCMV infection by the peak value of HCMV antigenemia assay in our study was similar with previous results, although the sensitivity was relatively low.

머리염색이 인체에 미치는 영향

윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

신경과 질환의 체성감각 유발 순목반사

차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.5

재난관리조직의 실태분석과 발전방안

권오한,남상화,이춘하 한국화재소방학회 2001 한국화재소방학회논문지 Vol.15 No.1

재난관리업무 자체가 매우 복잡하고 각 부처간에 서로 연계되는 분야가 많아 여러 가지 어려움이 많지만 행정 조직상으로 볼 때 재난관리업무가 분산되어 있으면서도 총괄 조정하는 기능이 미흡하고, 재난관리 담당인력이 부족 할 뿐만 아니라 전문성도 결여되어 있고, 대개는 이들 부서들이 업무가 과중하여 기피하는 부서 정도로 인식되고 있는 실정이다. 특히, 우리나라의 경우 재난을 양분화하여 인위재난 및 자연재해를 분리하여 그 소관부서 및 법체계를 달리하고 있어 비효율적 재난관리체제를 취하고 있어 현재 미국에서의 재난이론의 개념 즉 "재난은 그 유형에 관계없이 계획, 수습 및 복구의 양태는 동일하다"는 원칙에 반하는 것이다. 그것은 지방자치제가 시행되면서 아직은 중앙과 지방의 역할이 불분명하거나 분명하더라도 서로 그 역할을 해 내기를 바라는 점은 철저한 계획수립과 점검으로 해결해 나가야 할 사항이다. Ⅰ.Introduction. A government goal at the present is established to make a welfare nation and to keep people's safe living, but it is criticized that when a large-scale disaster happens, the authority concerned could not deal with it, causing many people injured and material damage. Moreover, in these days, cities have many risk factors. Extremely large and intelligent building, industrial facilities and underground equipment have many risk themselevs along with scientific progress. To cope with disaster effectively, government must have efficient organization, skillful personnel, tool, facilities and so on. To reduce the damages, what's the most effective government organization? Ⅱ. Government organization for managing disaster In a few decades, a large-sized accidents broke out in Korea, for example, collapse of Sampoong deprtment store, break of Sungsoo bridge, explosion of Daegu city gas, gas explosion accident at Ahyon-dong etc. But government has not any adequate response organi zation. Especially, after collapse of Sampoong department store broke out, Disaster Management Act is enacted to solve the problem. According to Disaster management Act, disaster is limited in manmaid disaster. Therefore, in this thesis, disaster management is inspected theoretically, organization of disaster management for pattern of disaster, and role, duty of government organization, emergency relief organization system and actual conditions art analyzed. There are some problems. There art trials and errors. The government has changed the disaster management. But zation by the disaster management law. The organization consists of central and local government. But both of government do not work together harmoniously. In thesis, I could like to introduce the advanced nations disaster management organization, and study our central, local government organization. Ⅲ. conclusion Change and development of the government disaster managementorganization is the goal of this theses. We have to increase public service in response and manage disaster. Protecting civilian's life from the disaster is very important responsibility of government. There would be better way of government disaster management organization.

편측 하악 과두골절의 관혈적 치료에 있어서 예후에 영향을 줄 수 있는 인자들에 관한 임상 통계학적 연구

성현모,이동근,민승기,오승환,장관식 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.1

The purpose of this study is to reveal the factors leading to the problem of unilateral condylar fractures and suggest a treatment guideline of treatment for good prognosis in surgical treatment, The factors can be age, sex, fracture site, degree of displacement, posterior occlusion loss, post-operative alteration of condylar head position, post-operatlve condylar head resorption, and maxillomandibular fixation period. One hundred and eleven patients with unilateral condylar fractures, who were treated by surgical method from 1990 Feb. to 2000 Feb., were studied. Minimum follow-up period was 6 months. The results were as follows ; 1. In the age group of 41 ∼60, females had significantly higher complication rate than males, therefore we must be careful about treatment of female in this age group 2 In level I fractures of the mandibular condyle, because there were abundant complications when the patients were treated with fragment removal, conservative treatment is recommended over the surgical approach. 3. There were no differences in the complication rate, in the level Ⅱ, Ⅲ fractures. but were severe complications in the cases of patients treated by Dr.Nam's method or fragment removal. Therefore, open reduction and internal fixation is recommended over Dr.Nam's method or fragment removal. 4. In level Ⅳ fractures, open reduction and internal fixation is recommended 5. Although there was a higher complication rate depending on the degree of deviation, there was no correlation between the degree of deviation and development of complications in each level of fracture 6. Because the complication rate was higher in cases of condylar resorption, vertical dimension loss, and alteration of condylar head position, we must make an effort to prevent such complications during treatment

美國 南部社會의 Plantation에 대한 考察 : 南北戰爭以前의 奴隸制度를 中心으로

권상선 新羅大學校 1993 論文集 Vol.35 No.1

In modern society it is almost out of question that most of political troubles are based on economic interest. Slavery in America was not exceptional in this respect. The slavery in Southern society was possible, for there were rich resources such as men and land, and the proper environment for it. But the problem was that this system functioned as an obstacle to hinder the growth of capitalism. It is because not noly the root of Southern capitalism, different from Northern capitalism, was in agriculture, especially in a cotton, but also most capital was invested in slavery system. Accordingly since the foundation of the United States, there has been a peculiar social structure of the South and the North until the 19th century. In this paper I tried to show the influence of plantation and slave labor on the social development of Southern society, surveying various economic conditions of the South. First, why did slavery system even in the 19th century in America expand? second, what was the foundation to develop the slavery system? Third, what was the result in the process of the development of Southerly society that it brougth about? The answers to these questions I have sought, mainly from the viewpoint of economy. My final conclusion is that the slavery system caused the Civil War, and that economically it hindered the development of capitalism, and socially it hampered the development of true democracy.

특발성 부갑상선 기능 저하증 환자에서의 가역적 파킨슨증 1례

전성만,김상우,김상수,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

편측안면경련 환자에서의 임상적 중증도를 평가하기 위한 전기생리학적 연구

전성만,김종국,정재익,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

동통성 안근마비를 나타낸 양측성 자발성 경동맥해면정맥동루 2례

전성만,박경원,차재관,김상호,김재우,최순섭 대한신경과학회 1997 대한신경과학회지 Vol.15 No.5

釜山市 有料公園의 植物 및 野鼠類相에 관한 硏究

權相洙,南廷七,朴承範 동아대학교 환경문제연구소 1988 硏究報告 Vol.11 No.1

This experiment was conducted in the three areas of pay park in pusan city for eight times from March to December in order to the aspect of plants and protect forest injury of field mice. The results were obtained as follows : 1. The numbers of flora in the survey area, the numbers of Family was appeared to 58, and the numbers of Sepcies was appeared to 184. The species of bload leaved evergreen trees of that was investigated totally to 25, and the it's ratio was found to 36% in comparison with the whole country. 2. The species of field mice were Apodemus agrarius coreae. Apodemus speciosus peninsulae, Clethrionomys rufocanus regulus and Crocidura suaveolens shantungensis. 3. The 66 individuals of field mice were collected from 2, 745 traps. 4. A total of 66 field mice collected were composed with 48.5% in Apodemus speciosus peninsulae, 34.8% in Crocidura suaveolens shantungensis, 9.1% in Apodemus agrarius coreae and 7.6% in Clethrionomys rufocanus regulue. 5. The locational proportions of field mice collected were 3.3%, 3.0% and 1.0% in station. Ⅱ, Ⅲ and Ⅰ, respectively. 6. Apodemus speciosus peninsulae and clethrionomys rufocanus regulue was not collected at the station Ⅰ. 7. The body weight ranged from 18 to 41.9g in Apodemus agrarius coreae, from 9 to 44.9g in Apodemus speciosus peninsulae, from 18 to 35.9g in clethrionomys rufocanus regulue. It's average weight was 27.8g in Apodemus agrarius coreae, 28.4g in Apodemus speciosus peninsulae and 23.7g in clethrionomys rufocanus regulue. 8. The ratio of female to male of field mice was 0.67 to 0.33 in apodemus agrarius careae, 0.47 to 0.53 in Apodemus speciosus peninsulae and 0.4 to 0.6 in Clethrionomys rufocanus regulue. 9. The average body length of field mice was 95.97㎜ in Apodemus speciosus peninsulae, 95.20㎜ in Clethrionomys rufocanus regulue and 94.83㎜ in Apodemus agrarius coreae. 10. The everage tail length of field mice was 94.84㎜ in Apodemus speciosus peninsulae, 76.67㎜ in Apodemus agrarius coreae and 37.20㎜ in Clethronomys rufocanus regulue. 11. The everage ear length of field mice was 15.83㎜ in Apodemus speciosus peninsulae, 14.08㎜ in Apodemus agrarius coreae and 13.80㎜ in Clethrionomys rufocanus regulue. 12. The breeding period of field mice was between March and September in Pusan area. 13. The average fetal number of field mice was 5.1 in Apodemus speciosus peninsulae, 4.5 in Crocidura suaveolens shantungensis and 3.0 in Apodemus agrarius coreae.