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Roxithromycin 으로 치료 후 호전을 보인 미만성 범세기관지염 1예
어성준,박성우,이준혁,장안수,박춘식 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2
Diffuse panbronchiolitis is a clinical pathologic condition characterized by chronic inflammation of respiratory bronchioles, with clinical features that position it as a differential diagnosis among the sinopulmonary syndromes. We experienced 46-year-old male patient who complained of dyspnea and productive sputum for 2 years. Diagnosis was made by the clinical and radiological features and confirmed by transbronchial biopsy. The clinical findings included chronic sinusits, productive cough,dyspnea, rhonchi, and wheezes. High resolution computerized tomography showed a diffuse nodular pattern, airway ectasia, and airway wall thickening. The biopsy showed interstitial accumulation of foam cells and lymphoid cells in the walls of respiratory bronchioles. We treated low does of roxithromycin, After 8 months, the patient nearly improved symptoms and HRCT findings.
( Kwang Min Kim ),( Sung June Eo ),( Geum Youn Gwak ),( Moon Seok Choi ),( Joon Hyeok Lee ),( Kwang Cheol Koh ),( Byung Chul Yoo ),( Seung Woon Paik ) 대한간학회 2011 Gut and Liver Vol.5 No.4
Background/Aims: The notion that acute hepatitis A superimposed on chronic hepatitis B infection leads to a worse outcome than acute hepatitis A alone remains controversial. The aim of this study was to determine the infl uence of the presence of hepatitis B surface antigen (HBsAg) on the severity of acute hepatitis A. Methods: We retrospectively analyzed 449 patients hospitalized for acute hepatitis A from January 2000 to February 2010 and compared clinical outcomes based on the presence of HBsAg. Results: Of the 449 patients, 30 patients were in the HBsAg-positive group and 419 in the HBsAg-negative group. The HBsAg-positive group was older than the HBsAg-negative group (36.1±8.3 vs 31.8±8.5 years, p=0.004); however, other baseline characteristics were similar between the 2 groups. Mean peak values of prothrombin time, serum total bilirubin, and serum creatinine at admission were significantly higher in the HBsAg-positive group. When comparing clinical outcomes between the 2 groups, gastrointestinal bleeding, acute renal failure, and acute liver failure were more frequently observed in the HBsAg-positive group. In particular, the incidence of acute liver failure was approximately 9-fold higher in the HBsAg-positive group than in the HBsAg-negative group (23.3% vs 3.3%; odds ratio [OR], 8.80; p<0.001). Multivariate analysis showed that HBsAg (OR, 7.43; 95% confi dence interval [CI], 2.56 to 21.57) and age (OR, 1.07; 95% CI, 1.02 to 1.13) were independent risk factors for the occurrence of acute liver failure. Conclusions: In patients with chronic hepatitis B infection, acute hepatitis A is associated with more severe clinical outcomes, including acute liver failure, compared with patients with acute hepatitis A alone. (Gut Liver 2011;5:500-505)
12주간의 수중운동이 노인 골관절염 환자의 동적평형성과 통증요인에 미치는 영향
임순영(Im, Sun-Young),어수주(Eo, Su-Ju),김송준(Kim, Song-June),허성훈(Hur, Sung-Hoon),안경준(An, Kyung-Jun),이장규(Lee, Jang-Kyu),이종삼(Lee, Jong-Sam) 한국산학기술학회 2016 한국산학기술학회논문지 Vol.17 No.2
본 논문은 관절염을 앓고 있는 노인여성(환자군; 65.25±5.9세, 11명)과 일반 노인여성(통제군; 64.50±7세, 11명)을 대상으로 12주간의 수중운동(주 3회)을 실시 한 후 동적평형성과 통증(통증자각도)의 변화를 알아보고자 실시되었다. 동적평 형성은 시각정보의 유무에 따라 개안 시와 폐안 시로 나누어 측정하였다. 12주간의 수중운동에 따른 개안 시 동적평형성은 관절염 환자군(p<.001)과 통제군(p<.05)에서 유의하게 향상되었고, 폐안 시 관절염 환자군에서도 유의하게 향상된 결과를 보였다(p<.05). 또한, 통증자각도(VAS) 평가에 의한 통증 변화는 관절염 환자 군의 10요인(푹신한 의자에 똑바로 앉아있기 힘든가, p<.01), 11요인(누워있을 때 통증이 덜해지는가, p<.05), 12요인(통증 때문에 일상생활에 지장이 있는가, p<.05), 13요인(통증 때문에 직장일 또는 집안일에 지장이 있는가, p<.01)에서 유의한 통증 감소가 나타났다. 본 연구 결과를 통해 12주간의 수중 운동은 골관절염 노인 환자에게 개안 시와 폐안 시 모두 동적평형 능력을 향상 시키고, 일부 통증요인 감소에 효과적인 운동임을 알 수 있었다 This study evaluated the dynamic balance and pain after 12 weeks aquatic exercise in old osteoarthritis patients. The dynamic balances were assessed using 2 different experimental conditions (Open Eye Condition; OEC, Closed Eye Condition; CEC). Twenty-two subjects were assigned one of the two experimental groups: arthritis group (ART, age=65.25±5.9, n=11), control group(CON, age=64.50±7, n=11). All subjects participated in the aquatic exercise program three times a week for 12 weeks. The dynamic balances (OEC (p<.001), CEC (p<.05)) capability were improved significantly in the ART group after 12 week aquatic exercise. Visual Analogue Scale (VAS) was decreased significantly [Factor 10(Soft chair, p< 0.01), 11 (Lying down, p< 0.05), 12(Handicap, p< 0.05), 13 (Work interference, p< 0.01)] in the ART group. In conclusion, aquatic exercise was effective in improving the overall health status and the capacity of dynamic balances and reducing the degree of pain in osteoarthritis patients.