바터 팽대부에 생긴 유암종 1예

강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

가령에 따른 백서 악관절 원판의 형태 및 미세구조적 변화

배용철,성재현,경희문,서혜경 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.2

백서에 있어서 가령에 따라 악관절 원판에 가하여지는 기계적 부하의 변화에 따른 악관절 원판의 형태, 탄성섬유 및 세포의 미세구조의 적응등의 변화양상을 관찰하기 위하여, 생후 1일, 7일, 17일, 27일, 55일, 1년 이상군의 백서의 악관절 부위를 적출하여 광학 및 전자현미경으로 관찰하여 다음과 같은 결론을 얻었다. 악관절 원판의 형태는 1일 및 7일군에서는 중앙부의 얇은 부위가 전후방으로 상당히 길게 뻗쳐 있고 전부 및 후부의 최대 풍융부를 향한 경사가 완만하여 하악와 및 하악과두에 적합되지 않는 양상을 보였으나, 17일군부터는 전부 및 후부가 하악와쪽으로 풍융해짐과 동시에 중앙부의 얇은 부위가 전후방으로 좁아지고 전부 및 후부의 최대 풍융부를 향한 경사가 급하여져, 악관절 원판이 하악과두를 감싸는 형태를 취하여 하악와 및 하악과두에 적합되어 가는 양상을 보였다. 가령에 따라 세포밀도는 점점 감소하였으며, 1일 및7일군에서는 세포내 골지장치, 과립성 내형질망, 유리 리보솜 등의 세포질 및 세포간 기질을 활발하게 합성하는 세포 소기관들이 발달 되어 있었으나 세포질내 세사는 발달되어 있지 않았다. 17일, 27일 및 55일에서는 기질합성에 관여하는 세포 소기관의 발달과 아울러 손가락 모양의 세포돌기, 용해소체, 사립체등의 세포간 기질의 개조에 관여하는 세포 소기관이 발달된 세포가 다수 관찰되었으며, 가령에 따라서 세포질내 세사가 점점 축적되어지는 양상을 보였고, 섬유성 물질에 둘러 싸인 chondroid cell들이 증가하였다. 1년이상군에서는 대부분이 세포가 chondroid cell로 구성되어 있었으며 세포질내의 대부분을 세사가 차지하고 세포내 소기관이 거의 발달되지 않는 등 대사 활동이 미약하며 주로 기계적 부하에 적응하기 위한 구조로 이루어져 있었으며 때로는 변성과정에 있는 세포도 다소 관찰되었다. The purpose of this study was to investigate changes in the shape and ultrastructrue of the articular disc of the rat mandibular joint with aging. Mechanical stress applied to the articular disc changes during neonatal, suckling, juvenile, adult and senile stages. Mandibular joints of 6 groups of rats (1-,7-,17-,27-,55-day and over-1-year groups) were removed en bloc and processed for light and electro microscopic study. The changes in the shape of articular disc were examined by light microscope in each group. Structural and ultrastructural changes in the articular disc were examined by light and electron microscope in each group. The results were as follows: In the 1-day and 7-day groups, the articular disc was long and slender in shape and the articular disc was not fitted with the shape of the mandibular fossa and condyle. However, after that time, the anterior and posterior portions of the articular disc were more bulged and the middle portion was shorter and biconcave. Thus the articuler disc was well fitted with the shape of the mandibular fossa and condyle. The cell density decreased wth aging. In the 1-day and 7-day groups, the Golgi apparatus, rough endoplasmic reticulum and free ribosome, which are involved in the synthesis of intracellular and extracellular matrix. were developed. In the 17-day, 27-day and 55-day groups, not only the cell organelles involved in the synthesis of the intracellular and exracellular matrix but also the cell organelles involved in the remodeling of the extracellular matrix(i.e., finger-like cell process, lysosome and mitochondria) were well developed. With advancing age, intracytoplasmic microfilaments were more accumulated and condroid cells increased. In the over-1-year group, the majority of cells of the articular disc were chondroid cells. The majority of cytoplasmic compartment were filled with intracytoplasmic microfilaments and cell organelles were not developed. Therefore, metabolic activites of the cell was markedly reduced and cells contained structures enduring mechanical stress, and cells which were in the process of degeneration were observed occasionally.

능이버섯 가공품이 스테이크용 우육의 품질에 미치는 영향

배윤환,이종숙,이경아,윤재돈,강동헌,이재성 동아시아식생활학회 2002 東아시아食生活學會誌 Vol.12 No.4

The possibility of using the dried powder form of Sarcodon aspratus fruitbody (a kind of mushrooms) as a meat tenderizer was explored in this study. The freeze-dried powder had higher protease activity compared to the hot air dried powder of S. aspratus. The powder kept higher activity when preserved at -20℃ than at ambient temperature. The hardness of the meat decreased and the cooking loss increased more rapidly when the meat was treated with the mushroom powder at ambient temperature than at -41℃. In terms of sensory evaluation, 0.1% of the powder based on the meat and 3 hours of treatment at 4℃ gave the highest acceptability score. In the comparison test, the meat was more acceptable when treated with the mushroom powder than with the imported commercial tenderizer. This led to the conclusion that it is quite feasible to develop a natural meat tenderizer using the Sarcodon aspratus fruitbody.

갑상선 초음파검진의 유용성

배오근,김재권,강명순,조영익,김임봉,신유진,임성규,서민호 한국건강관리협회 2000 건협 Report Vol.3 No.-

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

정자기장과 맥동전자기장이 MC3T3-E1 세포의 ALP 및 DNA 활성도에 미치는 영향

배성민,성재현,손정희 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.4

정자기장과 맥동전자기장이 배양 조골세포에 미치는 영향을 알아보고자 MC3T3-E1세포를 각 자기장하에서 배양하여 ALP활성도와 DNA의 합성능을 평가한 결과 다음과 같은 결과를 얻었다. 1. 정자기장을 가한 군에서 자석을 1,2,3개 가한 군(51~114.8mT)에서 대조군에 비하여 ALP의 유의성있는 증가가 나타났으며(p<0.05), 자석을 4개, 5개 가한 군(150mT)에서는 대조군에 비하여 ALP활성도에 차이가 나타나지 않았다. 2. 맥동성 전자기장에서는 대조군에 비하여 ALP활성도에 유의한 차이가 나타나지 않았다. 3. DNA합성능은 정자기장과 맥동성 전자기장을 가한 군 모두 대조군에 비하여 유의한 차이가 나타나지 않았다. 이상의 결과 정자기장에 의한 교정력은 골세포의 대사과정에 변화를 줄 수 있으므로, 치아이동에 어떠한 영향을 줄 수 있을 것으로 사료된다. The purpose of this study was to evaluate the effect of magnetic field on cellular activity of MC3T3-E1 cells. The celular activity was monitored by alkaline phosphatase and DNA synthetic activity in control, static magnetic field and pulsed electromagnetic field groups. A static magnetic field and pulsed electromagnetic field groups. A static magnetic field was applied to the cell by placing one, two, three, foue, and five samarium-cobalt magnets above and below each cell plate for 24hours per day. A pulsed electromagnetic field with a frequency of 100 herz was applied for 10 hours per day. After 10 days of magnetic field exposure, there were increase of alkaline phosphatase activity in static magnetic field groups consisted of one, two and three magnetic groups. Alkaline phosphaatase activities were not significant increase in alkaline phosphatase activity compared to control. DNA synthetic activity in both static and pulsed electromagnetic field group were not significantly different from that in control group. The result of this study suggest that magnetic field could have effect on the metabolism of bone cells related to the cellular metabolic process.

본태성 고혈압에서 염산에포니디핀 (NZ-105, 핀테20정�)의 유효성 및 안전성 : 제3상 다기관 임상시험 The phaseⅢ multicenter open trial

배종화,손일석,강흥선,조정휘,강재헌,김성원,이선영,양윤준,김영식,선우성 대한간질학회 2003 대한간질학회지 Vol.9 No.1

水産專門大學 漁業科 敎育課程 開發硏究

裵錫悌,宋之浩,李吉來,鄭興基,洪聖根,趙鳳坤,朴種洙 군산대학교 1983 群山水産專門大學 硏究報告 Vol.17 No.1

In order to develop the curriculum of the fishery department in the fisheries Jr. college, We have collected and analyzed the domistic and foreign data adquated to the fishey department under the international trend, also we gathered the opinion from the inquiring paper investigation and consultation to the industrial field, concerned college and graduate during the 6 month from September 1982. The fishery department curriculum in fisheries Jr. college will be industrialized with the concerned technics and knowledge in relation to speciality of maritime affairs. Accordingly, we have developed the adquate curriculum which is practical and can be cultivated the technician to adopt in the industrial society.

인증과 무결성을 위한 웨이블릿 계수의 비트 플래인 기반 워터마킹

배재민,이신주,정성환 국립7개대학공동논문집간행위원회 2001 공업기술연구 Vol.1 No.-

We proposed a fragile watermark using selective bit plane of wavelet coefficient. Wong's method inserts a watermark into the LSB. It is a block-based approach in the spatial domain. We improve its related problems by selecting the inserted bit plane randomly with a secret key and processing the watermark in the wavelet transform domain. Through some experiments, our scheme improves the image quality of about 2-8dB, compared with Wong's method. It can recognize the minute modification in the intensity. The other modifying attacks including object-addition can be easily detected. Our approach also confirms that the exact location of modification can be found in the extracted watermark.

백서 하악골의 기능적 전방위가 악관절 원판에 미치는 영향

배용철,경희문,장병천,성재현 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.4

This study was conducted to examine the changes in the shape of the Sprague-Dawley rats' articular disk following postural hyperpropulsion by observing their articular specimens through light and electronic microscopes after following 2-week and 4-week postural hyperpropulsion from their four weeks of age. The findings of this study are summarized as follow. It was shown that as compared with the control group, the experimental group indicated a significant increase in thickness of the 2-week groups' anterior and posterior portion of the articular disc. The experimental group showed statistically more significant increase in thickness of the 4-week groups' anterior portion of the articular disc than the control group. Light micrograph showed that the experimental group had more fibroblast in the anterior portion of the 2-week and 4-week groups than the comparing group. The 2-week groups showed in the findings through the electronic microscope that there were found the well developed and dilated RER which see-ms to actively synthesize the extracellular matrix including collagen, the cells with the well developed RER without distention which seems to actively synthesize the intracellular microfilaments due to the well developed free ribosome, and the typical chondroid cells. In addition, there was more fibroblast cell with the distended and well developed RER in the anterior area of the experimental group than that of the control group while fibroblast with the well developed RER and free ribosome was quite abundat. Based on the above result of this study, it was shown that the functional hyperpropulsion of the mandible causes the changes in the nature of the mechanical load to the certain portion of the articular disk. As a result, it seems that there may be occurred some changes in morphology of the disc by adaptation or confrontation with these changes at the cellular level.