건강한 성인에서 발병한 칸디다와 연관된 위궤양 1례

박지훈,이상혁,김희,이재호,박성재,지삼룡,양성연,박은택,이연재,설상영,정정명,강미선 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Fungus such as Candida albicans is a normal flora that is frequently found in the oral cavity, gastrointestinal tract, genitourinary tract, vaginal mucosa in a normal person. However, candida can cause opportunistic infection in an immune compromised host. Candidiasis has broad spectrum of disease from mucocutaneous infection to invasive or disseminated infection. But, it is rarely reported that candida is associaed with gastrointestinal tract disease in a healthy adult. The case of gastric ulcer associated with candida particularly in a health adult is reported with relevant literature.

젊은 남자에게 발생한 통상성 간질성 폐렴과 동반된 폐암 1예

박종숙,이준혁,박성우,장안수,박춘식,박재성,백상현,고은석,신화균 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

Usual interstitial pneumonia(UIP) is relatively rare disease of lung parenchyme under the age of 50. Lung cancer is reported to occur as a complication of UIP, but has not been reported in young age patient with UIP in Korea. A 35-year-old man was admitted to the hospital because of dyspnea, cough and mild fever. He had been suffered from dyspnea during 3 years. The dyspnea worsened recent 1 month ago. He had been treated with pneumonia at another hospital during 4 months before this admission. Chest radiographs and High resolution CT showed subpleural and basal dominant reticular opacities in both lung with no change until now. He was smoker and his occupation was car engine-man dealing with benzene. UIP is suspected by history and radiologic findings. Operation for open lung biopsy was performed to obtain lung specimen via video-assisted thoracoscopic surgery. Patient's pathologic examination showed UIP combined with adenocarcinoma in RLL superior segment and posterobasal segment and RLL lobectomy was done. After operation, the patient has been in cancer free condition so far. We report a case of UIP combined with lung cancer in young man with brief review of the literature.

Pro is Still Case-Ungoverned

Park, Sung-Hyuk 서울대학교 어학연구소 1990 語學硏究 Vol.26 No.2

Ths main purpose of this squib is to show that unlike Lasnik and Uriagereka's (1988) claim, the Case-theoretic approach to the distribution of PRO in English can substantially broaden its empirical coverage if we adopt Park's (1988a) proposal that Chomsky's (1981) PRO-theorem be recast as the PRO-condition, which states that PRO must be Case-ungoverned (or PRO may not be Case-governed). In order to make the PRO-condition work properly, we invoke the Case theory of Chomsky (1986a), where case-marking consists of two separate steps: Case-assignment and Case-realization. We also propose with respect to the Case theory that the adjacency condition on Case-assignment of Stowell (1981) be reinterpreted as a condition for Case-realization. In addition, the Case-absorbing properties of passive morphology will be redressed as the properties that absorb the Case-realizing ability of its host verb.

비·부비동 종양의 신생혈관 형성에서 COX-2 및 VEGF의 역할

도남용,박성용,조성일,윤혁수,박선홍,박영균,권대승,임성철 조선대학교 2003 The Medical Journal of Chosun University Vol.28 No.1

Background and Objectives : COX-2, the inducible form of cyclooxygenase(COX), is upregulated in transformed cells and in malignant cells, which have important roles in promotion of colorectal carcinogenesis, invasiveness and angiogenesis. Vascular endothelial growth factor(VEGF) may act as endothelial cell mitogen in various cancer tissues. It will increase tumor growth and angiogenesis. Aims of this study were to asses COX-2/VEGF expression and it's clinical correlation in sinonasal tumors and to investigate the effects on angiogenesis also. Materials and Method : The study samples were obtained from surgical removal of 27 cases of inverted papilloma(IPs), 5 cases of IP with malignant transformation(IP-MT), 16 cases of Squamous cell carcinoma(SCC) in sinonasal cavity COX-2 and VEGF expressions were assessed by immunohistochemical staining. Synchronism of COX-2/VEGF expression in one tumor cell was demonstrated with double immunofluorescence technique. Results : The expression rates of COX-2 were 37% in IP, 80% in IP-MT and 100% in SCC. The positive rates of VEGF were 29 6% in IP, 100% in IP-MT and SCC. COX-2 and VEGF expressions were increased as tumor progressed, and there is a positive correlation between COX-2 &EGF expressions. All clinical features which were compared are not associated with COX-2 &EGF expressions except malignant change in IP(p=0 028). Synchronism of COX-2/VEGF expressions was noted in all positive immunostaining samples. Conclusion : These findings suggest the role of COX-2 pathway could be involved in sinonasal tumor angiogenesis, which is modulated by VEGF COX-2 may act as autocrine factor in VEGF expression. There is a potential role for selective COX-2 inhibitors in the treatment of these lesions.

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

보호지역 경계조정을 위한 공간의사결정지원모델 연구 -지리산 국립공원을 사례로-

성혜정 ( Hye Jung Sung ),권혁수 ( Hyuk Soo Kwon ),서창완 ( Chang Wan Seo ),박종화 ( Chong Hwa Park ) 한국환경복원기술학회 2011 한국환경복원기술학회지 Vol.14 No.3

The purpose of this study are to develop a SDSS (Spatial Decision Support System) that can incorporate diverse opinions of stakeholders related the designation of protected areas (PA), and to employ the model for the readjustment of the boundary line of the Jirisan National Park of Korea. The SDSS would lead to more rational and less controversial decision-making during the expansion or removal of PA in Korea. Research methods are as follows. Firstly, to select evaluation criteria for SDSS for PA designation by using expert interview and literature survey. Secondly, to measure their preferences on the designation of additional PA or the removal of a part of PA based on the opinions of various stakeholders such as local residents, environmental groups, or public officials. Thirdly, to produce conservation priority maps based on a multi-criteria decision making technique. The SDSS would be used to rational decision making for the expansion of PA or the release of a certain part of PA by reflecting diverse preferences on biodiversity conservation and economic interest of residents. The visualization of conservation priority maps would also increase the efficiency of such decision making processes. The evaluation criteria for the expansion of PA for biodiversity conservation includes vegetation conservation value, wildlife conservation value, and the habitats of key species. The evaluation criteria for the removal of PA includes the proximity to roads and the boundary of PA, land use types, and conservation zoning of the PA. Preference weights are based on data collected from the Jirisan National Park. Both the conservation priority and removal priority maps are based on land parcels so that property rights of all parcels would be correctly represented.

바터 팽대부에 생긴 유암종 1예

강명주,지삼룡,박석주,이재익,조영완,김준영,박성재,박은택,이연재,이상혁,설상영,배상균 인제대학교 2006 仁濟醫學 Vol.27 No.-

Carcinoid tumors have been reported in a wide range of organs but most commonly involve the lungs, bronchi and gastrointestinal tract. Within the gastrointestinal tract, appendix is the most common location for carcinoid, followed by the distal small intestine, the rectum, and the stomach. Among these, primary involvement of the ampulla of Vater is extremely rare. We report a case of carcinoid tumor of ampulla of Vater. A 62-year-old man presented with epigastric soreness. Gastroduodenal endoscopy showed hyperemic bulging mass on ampulla of Vater and diagnosed as carcinoid tumor by histologic finding, with immunohistochemical study. In ^(111)In-octreoscan, tumor had regional lymph node metastasis, but no evidence of distant metastasis. Pancreatoduodenectomy with lymph node dissection was performed.

수입각증후군에 의한 급성 복증 1례

정은욱,지삼룡,이영태,박지훈,김동기,제인수,채두근,박성재,박은택,이연재,이상혁,설상영,정정명 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Afferent loop syndrome is an uncommon complication of a gastrectomy and Billroth Ⅱ reconstruction. It may cause symtoms at any time from the first postoperative day to many years after the gastrectomy. Afferent loop syndrome is characterized by abdominal pain, vomiting and elevation of serum amylase. Thus, it is difficult to differentiate afferent loop syndrome from other cause of acute pancreatitis. However, the history of gastrectomy can be an important clue for diagnosing afferent loop syndrome. We experienced one case of chronic afferent loop syndrome with acute pancreatitis. After appropriate management, the abdominal pain disappeared and serum amylase level decreased. We report this case with a review of relevant literatures.

A-結束理論과 θ-結束理論 比較考

朴勝赫 이화여자대학교 한국문화연구원 1990 韓國文化硏究院 論叢 Vol.58 No.-

It can be claimed that Chomskys (1981; 1982; 1986a) A-binding theory is position-oriented in that it basically assumes that each and every element involved in the binding theory, be it phonetically realized or not, must occupy a position on the syntactic structure. Williams (1985;1987;1989), on the other hand, assumes that it is not the structural (syntactic) configuration that governs binding, but rather the θ-structure. Chomskys (1986a) theory can explain a wide range of binding phenomena, including the NIC effect and the anaphoric relation in the possessive construction. The weakness of Chomskys A-binding theory, however, is that it cannot successfully handle such binding phenomena as occurring in the reconstruction structure and the construction in which the implicit argument plays a crucial role. In Williamss θ-binding theory, on the other hand, it is unnecessary for the element involved in anaphora in general to be realized syntactically. As a consequence, binding effects in the construction which contains implicit arguments can be dealt with in a natural manner. Furthermore, Williamss theory sheds much light on the binding phenomenon in the reconstruction structure, which has so far been a major problem with Chomskys theory. In spite of the fact that Williamss theory provides fresh insight into the study of binding, we should point out that it cannot handle the overall binding effects in any satisfactory way. In particular, the θ-binding theory does not seem to adequately deal with the NIC effect and the anaphoric relation in the possessive construction. Although the A-binding theory and the θ-binding theory do not appear to be easily unifiable, they may, in some sense, be viewed as complementary. For the present, it seems true that Chomskys theory enjoys by far wider empirical coverage than Williamss. The latter theory is worthy of pursuing nevertheless since in some cases it provides us with explanations more natural than those of the former.

英語의 擴大 投射 原理 效果

朴勝赫 이화여자대학교 한국문화연구원 1994 韓國文化硏究院 論叢 Vol.65 No.1-2

According to Chomskys(1993) minimalist theory, the Extended Projection Principle (EPP) in English is not an independent principle any more, but derived from other deeper principles (or certain language-particular parameters) of the grammar. Chomsky (1993) claims that the requirement that clauses have subjects in English can be explained by assuming that the DP feature of the functional head T is strong in English. Since strong features become illegitimate objects at PF if they are not checked off prior to Spell-out, the subject DP must move out of its containing VP into the checking domain of T, where its features are checked by T. As a result of this checking operation, the strong DP feature of T is discharged and hence eliminated for convergence at PF; otherwise, the derivation crashes. In order to make his account of the EPP effect in English work, Chomsky (1993) assumes, among others : (i) T adjoins to Ages pre-Spell-out, and that (ii) the subject DP moves into the checking domain of T before Spell-out. These assumptions, however, do not seem to stand on solid grounds when we take Chomskys (1993) Principle of Greed into consideration. The purpose of this paper is thus to show that the account of the EPP effect in English presented by Chomsky (1993) within the framework of his minimalist theory is untenable in light of the concept Greed, which plays an important role in the minimalist theory, and to provide a condition on the application of Greed so that the EPP effect in English can be accounted for in a more plausible way. We specifically raise the following questions: (ⅰ) Why does T adjoin to AgrS pre-Spell-out? (ⅱ) Where does the subject DP move to? and (ⅲ) Why does the subject DP move before Spell-out? Questions (ⅰ) and (ⅱ) are solved if we adopt Chomskys (1994) suggestions that agreement can be assigned without Case. According to this suggestion, the functional head T need not adjoin to AgrS to begin with since it can check the Case feature of the DP in its specifier position without movement to AgrS; hence the problem in (ⅰ) disappears in toto. Furthermore, if the specifier position of TP exists, as suggested in Chomsky (1994) (unlike in Chomsky (1993)), and the head T can check the Case feature of the element in [Spec, TP], the subject DP need not move into [Spec, AgrSP] but into [Spec, TP] for its Case feature checking. Question (ⅲ) is one of the most serious problem in Chomskys (1993; 1994) minimalist system and hence the core of the discussions in this paper. Chomsky (1994) assumes that Greed holds in the strong form : Move raises α to a position β only if morphological properties of α itself would not otherwise be satisfied in the derivation. However, this strong Greed does not motivate the movement of the subject DP is not strong but that of the functional head T is. Therefore, the movement of the subject DP itself but to the strong nature of the DP feature of T. In an effort to provide a plausible answer to the questions in (ⅲ) , we in this respect propose the following condition on the application of Greed : Move α for the checking of the morphological features of α by β may apply without regard for Procrastinate if it satisfies the morphological requirements of β at a given point in the derivation. As a consequence of the proposal, VP-internal subjects can now move to [Spec, TP] pre-Spell-out and their Case feature is checked by T, which on its part can discharge its strong feature. This checked strong feature of T can now be stripped away by Spell-out; hence the derivation converges. The same explanation holds good for the case of the exceptional Case marking construction, where the embedded infinitival complement clause shows the same EPP effect as in ordinary tensed clauses, if we adopt Lasniks (1993) assumption that the DP feature of the infinitival T is also strong.