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      • Measurements of surgeons’ exposure to ionizing radiation dose: comparison of conventional and mini C-arm fluoroscopy

        Sung, K. H.,Min, E.,Chung, C. Y.,Jo, B. C.,Park, M. S.,Lee, K. SAGE Publications 2016 The journal of hand surgery. journal of the Britis Vol.41 No.3

        <P>This study was performed to measure the equivalent scattered radiation dose delivered to susceptible organs while simulating orthopaedic surgery using conventional and mini C-arm fluoroscopy. In addition, shielding effects on the thyroid, thymus, and gonad, and the direct exposure delivered to the patient's hands were also compared. A conventional and mini C-arms were installed in an operating room, and a hand and an operator phantom were used to simulate a patient's hand and a surgeon. Photoluminescence dosimeters were used to measure the equivalent dose by scattered radiation arriving at the thyroid, thymus, and gonad on a whole-body phantom in the position of the surgeon. Equivalent scattered radiation doses were measured in four groups: (1) unshielded conventional C-arm group; (2) unshielded mini C-arm group; (3) lead-shielded conventional C-arm group; and (4) lead-shielded mini C-arm group. Equivalent scattered radiation doses to the unshielded group were significantly lower in the mini C-arm group than those in the conventional C-arm group for all organs. The gonad in the lead-shielded conventional C-arm group showed the highest equivalent dose among operator-susceptible organs, and radiation dose was reduced by approximately 96% compared with that in the unshielded group. Scattered radiation was not detected in any susceptible organ in the lead-shielded mini C-arm group. The direct radiation dose to the hand phantom measured from the mini C-arm was significantly lower than that measured from the conventional C-arm. The results show that the equivalent scattered radiation dose to the surgeon's susceptible organs and the direct radiation dose to a patient's hand can be decreased significantly by using a mini C-arm rather than a conventional C-arm. However, protective lead garments, such as a thyroid shield and apron, should be applied to minimize radiation exposure to susceptible organs, even during use of mini C-arm fluoroscopy.</P>

      • 오대산 신갈나무림의 낙엽생산과 유기탄소 동태

        장미나 ( Mi Na Jang ),김성용 ( Sung Yong Kim ),( Azyleah C. Abino ),김창현 ( Chang Hyun Kim ),이중효 ( Jung Hyo Lee ),이영진 ( Young Jin Lee ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

        본 연구는 백두대간에 위치하고 있는 오대산 국립공원 신갈나무림을 대상으로 2012년 6월부터 2013년 5월까지 지상부와 지하부 현존량, 낙엽생산량, 낙엽층의 낙엽량과 토양의 유기탄소 분포를 조사하였으며, 탄소수지를 파악하기 위하여 토양호흡을 측정하였다. 오대산 신갈나무림에서 조사된 총유기탄소량은 93.07 ton C/ha으로, 지상부와 지하부의 유기탄소량은 각각 72.36 ton C/ha, 18.09 tonC/ha이었으며, 낙엽층과 토양의 유기탄소량은 각각 4.39 ton C/ha, 42.28 ton C/ha이었다. 오대산 신갈나무림에서 연간 광합성을 통하여 식물체에 고정되는 유기탄소량은 5.46 ton C/ha/yr로 임내 층위에 따라 교목층 4.26 ton C/ha/yr, 관목층 0.24 ton C/ha/yr, 초본층 0.95 ton C/ha/yr의 유기탄소가 고정되어 있다. 또한 조사기간 동안 낙엽을 통하여 임상으로 유입되는 유기탄소량은 2.840 tonC/ha/yr이었다. 토양호흡을 통하여 방출되는 탄소량은 5.52 ton C/ha/yr으로 이 중 미생물호흡을 통해 방출되는 탄소량은 2.98 ton C/ha/yr이고, 뿌리호흡을 통하여 방출되는 탄소량은 2.54 tonC/ha/yr이었다. 그 결과, 오대산 신갈나무림에서 연간 대기로부터 순 흡수하는 유기탄소는 2.48 tonC/ha/yr로 조사되었다. This study was conducted to estimate Litter Production and carbon budget of Quercus mongolica stands in the Mt. Odae National Park. Above and below ground standing biomass, litter layer, soil organic carbon, and soil respiration were measured to estimate the amount of carbon and the carbon budget from June 2012 through May 2013. Total amount of carbon was 93.07 ton C/ha attributed to above (72.36 ton C/ha) and below (18.09 ton C/ha) ground biomass, litter layer (4.39 ton C/ha) and soil organic carbon (42.28 ton C/ha). This was equivalent to 5.46 ton C/ha/yr where 4.26 ton C/ha/yr is from above and below ground biomass, 0.24 ton C/ha/yr from shrub and 0.95 ton C/ha/yr from herb. In addition, the amount of organic carbon returned to the forest through litterfall was 2.840 ton C/ha/yr. The amount of carbon evolved through soil respiration was 5.52 ton C/ha/yr to which 2.98 ton C/ha/yr was accounted for microbial respiration while the remaining 2.54 ton C/ha/yr was due to root respiration. Based on the estimation of the difference between Net Primary Production and microbial respiration, the amount of atmospheric carbon sequestered by Quercus mongolica stands was 2.48 ton C/ha/yr.

      • 오대산 소나무림의 유기탄소 분포 및 수지

        장미나 ( Mi Na Jang ),김성용 ( Sung Yong Kim ),( Azyleah C. Abino ),김창현 ( Chang Hyun Kim ),이중효 ( Jung Hyo Lee ),이영진 ( Young Jin Lee ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

        본 연구는 백두대간에 위치하고 있는 오대산 국립공원 소나무림을 대상으로 2012년 6월부터 2013년 5월까지 지상부와 지하부 현존량, 낙엽생산량, 낙엽층의 낙엽량과 토양의 유기탄소 분포를 조사하였으며, 탄소수지를 파악하기 위하여 토양호흡을 측정하였다. 오대산 소나무림에서 조사된 총 유기탄소량은 230.11 ton C/ha으로, 지상부와 지하부의 유기탄소량은 각각 182.78 ton C/ha, 45.70 tonC/ha이었으며, 낙엽층과 토양의 유기탄소량은 각각 5.98 ton C/ha, 45.40 ton C/ha이었다. 오대산 소 나무림에서 연간 광합성을 통하여 식물체에 고정되는 유기탄소량은 17.76 ton C/ha/yr로 임내 층위에 따라 유기탄소가 고정되어 있다. 또한 조사기간 동안 낙엽을 통하여 임상으로 유입되는 유기탄소 량은 3.233 ton C/ha/yr이었다. 토양호흡을 통하여 방출되는 탄소량은 5.76 ton C/ha/yr으로 이 중미생물호흡을 통해 방출되는 탄소량은 3.11 ton C/ha/yr이고, 뿌리호흡을 통하여 방출되는 탄소량은2.65 ton C/ha/yr이었다. 그 결과, 오대산 소나무림에서 연간 대기로부터 순 흡수하는 유기탄소는 14.65 ton C/ha/yr로 조사되었다. This study was conducted to estimate carbon sequestration and carbon budget of Pinus densiflora stands in the Mt. Odae National Park. Above and below ground standing biomass, litter layer, soil organic carbon, and soil respiration were measured to estimate the amount of carbon and the carbon budget from June 2012 through May 2013. Total amount of carbon was 230.11 ton C/ha attributed to above (182.78 ton C/ha) and below (45.70 ton C/ha) ground biomass, litter layer (5.98 ton C/ha) and soil organic carbon (45.40 ton C/ha). This was equivalent to 17.76 ton C/ha/yr from above and below ground biomass, shrub and herb. In addition, the amount of organic carbon returned to the forest through litterfall was 3.233 ton C/ha/yr. The amount of carbon evolved through soil respiration was 5.76 ton C/ha/yr to which 3.11 ton C/ha/yr was accounted for microbial respiration while the remaining 2.65 ton C/ha/yr was due to root respiration. Based on the estimation of the difference between Net Primary Production and microbial respiration, the amount of atmospheric carbon sequestered by Pinus densiflora stands was 14.65 ton C/ha/yr.

      • MRP1 Polymorphisms Associated With Citalopram Response in Patients With Major Depression

        Lee, Sung Hee,Lee, Min-Soo,Lee, Ji Hyun,Kim, So Won,Kang, Rhee-Hun,Choi, Myoung-Jin,Park, Sang Jin,Kim, Se Joo,Lee, Jae Myun,Cole, Susan P.C.,Lee, Min Goo Lippincott Williams Wilkins, Inc. 2010 JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY Vol.30 No.2

        Multidrug resistance protein 1 (MRP1, ABCC1) transports antidepressive agents in the endothelial cells of the blood-brain barrier. Therefore, polymorphisms in the MRP1 gene may affect the treatment response of antidepressants. This study was aimed to identify the association between genetic variations in MRP1/ABCC1 and the therapeutic response to the antidepressant citalopram. One hundred and twenty-three patients who had been treated with citalopram monotherapy to control their major depressive disorder were recruited, and genotype data from 64 patients who had completed their 8-week follow-up were evaluated together with those from 100 controls. Nine MRP1 single nucleotide polymorphisms (SNPs) showing more than 5% allele frequency in the Korean population were analyzed. The c.4002G>A, a synonymous SNP in exon 28, showed a strong association with the remission state at 8 weeks (P = 0.005, odds ratio [OR], 4.7, 95% confidence interval [CI], 1.5∼14.7). The c.4002G>A forms a linkage disequilibrium block with 3 other SNPs including c.5462T>A in the 3' untranslated region. Accordingly, the haplotype showed a significant association with the remission state (P = 0.014). Subsequent molecular studies also supported the association between these MRP1 polymorphisms and the citalopram response. Thus, kinetic studies using MRP1-enriched membrane vesicles revealed that citalopram is a substrate of MRP1 (Km = 1.99 μM, Vmax = 137 pmol/min per milligram protein). In addition, individuals with c.4002G>A or c.5462T>A polymorphisms showed higher MRP1 mRNA levels in peripheral blood cells. These results suggest that MRP1 polymorphisms may be a predictive marker of citalopram treatment in major depression.

      • KCI우수등재

        몇가지 사료 첨가제가 계란의 특정성분에 미치는 영향

        성기승,윤칠석,이남형,한찬규,이복희 한국축산학회 2000 한국축산학회지 Vol.42 No.1

        The experiment was conducted to determine the effects of various commercial feed additives on specific components in shell egg and to develop a new type of brand egg. Forty-four week old ISA Brown layers were randomly assigned to 8 treatments. Hens of each treatment were 300 and treatment was replicated 3 times. Experimental period was 10 weeks. The 8 treatments were as follows: astarich^ⓡ 2%(B), astarich^ⓡ 5%(C), chitin+chitosan 2%(D), omega-3 powder 2%(E), pyrogreen 1%(F), greenpia 0.2%(G), hydrogenated soy oil 3%(H) and commercial layer feed(A). Eggs were collected at day 0, 7, 14, 40 and 70 for chemical analyses. Chemical analyses were done for vitamins A and E, cholesterol and fatty acid profile of egg yolks. During the experimental period, the contents of vitamin A increased overall. Astarich^ⓡ 5%(C) group showed the highest amounts of vitamin A (11.14±3.93 ㎍/g yolk) whereas commercial layer feed goup(A) showed the lowest amounts of vitamin A(8.65±1.97 ㎍/g yolk). Vitamin E contents were significantly different among treatments at day 7, 40, and 70 (p$lt;0.05). Mean value of vitamin E (99.66±8.30 ㎍/g yolk) was the highest in omega-3(E) group and the lowest in pyrogreen (F) group (53.49±11.36 ㎍/g yolk). Yolk cholesterol contents tended to increase, although the fluctuation existed somewhat depending on the day of measurement. The highest value of yolk cholesterol(11.71±0.50㎎/g yolk) was observed in astarich^ⓡ 2%(B) group and the Lowest value(9.45±2.32㎎/g yolk) in pyrogreen (F) group. The mean compositions of yolk fatty acids during the experimental period were 37.3∼39.6% for saturated fatty acids(SFA), 39.3∼41.3% for monounsaturated fatty acids(MUFA), 16.2∼18.9% for omega-6 fatty acids and 2.20∼5.36% for omega-3 fatty acids. In general, the concentrations of SFA and omega-6 fatty acids decreased, while those of MUFA tended to increase. On the other hand, eicosapentaenoic acid(C_(20:5) ω6, EPA) and docosapentaenoic acid(C_(22:5) ω3, DPA) were detected only in astarich^ⓡ 5%(B) and omega-3(E) groups where the docosahexaenoic acid(C_(22:6) ω3, DHA) concentration was over twice higher than those of other group. The study proved both astarich^ⓡ and omega-3 powder were suitable to produce brand eggs specially high in certain components.

      • KCI등재SCIESCOPUS

        Ferroelectric properties of Mn-doped BiFeO<sub>3</sub> thin films

        Lee, M.H.,Park, J.S.,Kim, D.J.,Cho, H.J.,Sung, Y.S.,Kim, M.H.,Cho, J.H.,Choi, H.I.,Do, D.,Kim, W.J.,Kim, S.S.,Choi, B.C.,Song, T.K. Elsevier 2011 CURRENT APPLIED PHYSICS Vol.11 No.3

        Bi(Fe<SUB>0.99</SUB>Mn<SUB>0.01</SUB>)O<SUB>3</SUB> thin films were prepared on a Pt(111)/Ti/SiO<SUB>2</SUB>/Si(100) substrates by pulsed laser deposition at various deposition temperature, such as at 520 <SUP>o</SUP>C, 530 <SUP>o</SUP>C, and 540 <SUP>o</SUP>C, respectively. The film deposited at 540 <SUP>o</SUP>C exhibited better ferroelectric property such as large remnant polarization (2P<SUB>r</SUB> = 139 μC/cm<SUP>2</SUP>) and low coercive field (2E<SUB>c</SUB> = 630 kV/cm). However, high leakage current density was observed especially in a high electric field range. The improvements were attributed to the facts of highly (111)-preferred orientation and uniform large grain size when the film was deposited at 540 <SUP>o</SUP>C.

      • Rice C2-Domain Proteins Are Induced and Translocated to the Plasma Membrane in Response to a Fungal Elicitor

        Kim, Cha-Young,Koo, Yoon-Duck,Jin, Jing-Bo,Moon, Byeong-Cheol,Kang, Chang-Ho,Kim, Sun-Tae,Park, Byung-Ouk,Lee, So-Young,Kim, Man-Lyang,Hwang, In-Hwan,Kang, Kyu-Young,Bahk, Jeong-Dong,Lee, Sang-Yeol,,C Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

        ABSTRACT: Hundreds of proteins involved in signaling pathways contain a Ca^(2+)-dependent membrane-binding motif called the C2-domain. However, no small C2-domain proteins consisting of a single C2-domain have been reported in animal cells. We have isolated two cDNA clones, OsERG1a and OsERGIb, that encode two small C2-domain proteins of 156 and 159 amino acids, respectively, from a fungal elicitor-treated rice cDNA library. The clones are believed to have originated from a single gene by alternative splicing. Transcript levels of the OsERG1 gene are dramatically elvated by a fungal elicitor prepared from Magnaporthe grisea or by Ca^(2+) ions. The OsERG1 protein produced in Escherichia coli binds to phospholipid vesicles in a Ca^(2+)-dependent manner and is translocated to the plasma membrane of plant cells by treatment with either a fungal elicitor of a Ca^(2+)-ionophore. These results suggest that OsERG1 proteins containing a single C2-domain are involved in plant defense signaling systems.

      • SCIESCOPUSKCI등재

        Re-evaluation of the Optimum Dietary Vitamin C Requirement in Juvenile Eel, Anguilla japonica by Using L-ascorbyl-2-monophosphate

        Bae, Jun-Young,Park, Gun-Hyun,Yoo, Kwang-Yeol,Lee, Jeong-Yeol,Kim, Dae-Jung,Bai, Sung-Chul C. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.1

        This study was conducted to re-evaluate the dietary vitamin C requirement in juvenile eel, Anguilla japonica by using L-ascorbyl-2-monophosphate (AMP) as the vitamin C source. Five semi-purified experimental diets were formulated to contain 0 ($AMP_0$), 30 ($AMP_{24}$), 60 ($AMP_{52}$), 120 ($AMP_{108}$) and 1,200 ($AMP_{1137}$) mg AMP $kg^{-1}$ diet on a dry matter basis. Casein and defatted fish meal were used as the main protein sources in the semi-purified experimental diets. After a 4-week conditioning period, fish initially averaging $15{\pm}0.3$ g (mean${\pm}$SD) were randomly distributed to each aquarium as triplicate groups of 20 fish each. One of five experimental diets was fed on a DM basis to fish in three randomly selected aquaria, at a rate of 3% of total body weight, twice a day. At the end of the feeding trial, weight gain (WG) and specific growth rate (SGR) for fish fed $AMP_{52}$ and $AMP_{108}$ were significantly higher than those recorded for fish fed the control diet (p<0.05). Similarly, feed efficiency (FE) and protein efficiency ratio (PER) for fish fed $AMP_{52}$ were significantly higher than those for fish fed the control diet (p<0.05). Broken-line regression analysis on the basis of WG, SGR, FE and PER showed dietary vitamin C requirements of juvenile eel to be 41.1, 41.2, 43.9 and 43.1 (mg $kg^{-1}$ diet), respectively. These results indicated that the dietary vitamin C requirement could range from 41.1 to 43.9 mg $kg^{-1}$ diet in juvenile eel when L-ascorbyl-2-monophosphate was used as the dietary source of vitamin C.

      • KCI등재

        한우 c-fos 유전자의 염기서열 및 발현분석

        유성란,정행진,정기철,이준헌,조규완,최재관,나기준,상병찬 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.6

        Cellular FOS(c-fos) protein is a transcription factor that forms heterodimers mostly with c-jun family and stimulates the transcription of genes containing AP-1 regulatory elements. This c-fos expression can control growth and differentiation of various precursor cells including myoblasts. The controls by c-fos gene have been identified for affecting skeletal muscle fiber traits which are the key determinants of meat quality in pigs. As a first step for identifying the relationship between c-fos gene and meat quality traits in cattle, we fully sequenced 1,443 bp of Hanwoo c-fos mRNA and analyzed expression patterns from various organs and muscle tissues. The sequence identities of Hanwoo c-fos with that of human, pig and mouse showed 89.8%, 93.3% and rib muscle from 7 organs and 9 different parts of muscles investigated. These results presented here can be used as a valuable marker for meat quality related traits in cattle with further verification.

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