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청소년을 위한 교육 프로그램 개발·실시 및 평가에 관한 연구
계선자,이정우,김명자,박미석,송말희,유을용,김경아,정진희 대한가정학회 2003 Human Ecology Research(HER) Vol.41 No.8
The main goal of this program is to build a healthy adolescent culture by broadening the understanding of adolescents and recognition of the environment as well through the development of educational programs centering on the domains of peer relationships, intimacy in dating relationships and sex, leisure activities, and consumption life of adolescents. The program was carried out to 10 young boys and girls for two days/one night and the major findings of the effects of the program through a qualitative evaluation were as follows: First, the program provided adolescents with a proper opportunity to promote a sense of self-confidence through the self-reevaluation process. Secondly, the program provided adolescents with a chance to firmly recognize to become good friends with others though the enhancement of self-esteem, which helped them to build a healthy peer relationship. Thirdly, adolescents were able to promote their views on sex and sexual decision-making by acquiring a proper knowledge of intimacy in dating relationships and of sex, and by candidly expressing their own opinions on sex with instructors. Fourthly, the program provided adolescents with an opportunity to look back on their leisure life with family members which had been neglected thus far and to renew their recognition of active leisure activities. Fifthly, the program provided adolescents with a chance to reflect on their unplanned consumption life and to be firmly determined to refrain from impulsive purchasing and extravagance.
RP-HPLC에서 α-Hydroxy Carboxylic Acid류의 머무름거동에 관한 연구
문선영,김정수,유은아 성신여자대학교기초과학연구소 1996 基礎科學硏究誌 Vol.15 No.-
This study is an investigation of the effect of organic modifier volume in mobile phase, temperature and pH on the retention behavior in RP-HPLC. The retention data, capacity factors(k') of ten α-hydroxy acids were measured in the mobile phase with various compostion of methanol-phosphate buffer solution(v/v) at the same time that pH value was adjusted to 2.4, 4.4 and 6.4 respectively, and regulated the temperature from 10°C to 50°C with using c18 column. As expected, the decrease in retention time was mostly obtained as higher pH values than pKa values of solutes. That is explained by the increasing concentration of the ionized species when pH increase, but some of them did not coincide with that tendency. The effect of temperature on retention was investigated by the linerity of van't Hoff plot (R〉0.900), on the whole, at a lower volume fraction of organic modifier. And hydrophobicity index, log kw' obtained with experimental and the theoretical method showed an excellent correlation. Maximum retention time of these solutes is Mostly no more than double that of dead time, therefore another hydrophobicity index φ0 values were determined and discussed in several solute system.
청소년자녀와 어머니를 위한 세대간 이해증진 프로그램 개발 및 실시
김명자,이정우,계선자,박미선,송말희,김경아,박수선,유을용,정진희 대한가정학회 2003 Human Ecology Research(HER) Vol.41 No.1
The relationship between adolescent children and parents has a profound effect on not only the adolescents development into healthy adults but also the psychological welfare of the parent. A program focused to improve adolescents relationship with parents has not been developed until now. To achieve the educational goals enhancing mutual understanding, it is more effective to educate both the parents and adolescent childern. Thus, this study developed and carried out a program in which adolescent children and mothers, being fully in charge of raising children, participated. The study analyzed the program effects after implementing on 6 pairs of adolescent children and mothers. The results are as follows: 1) adolescent children and mothers placed high values on the fact that they can understand each other well, 2) both parties accepted each other by recognizing the inevitability of the generation gap, and 3) the program gave them a chance to admit that they should try to communicate openly. Most of all, adolescent children could find self-confidence while mothers could collect valuable data essential to raise children and build a new mother's role model adapting to social changes.
간암 환자에 합병된 Citrobacter braakii 패혈증 1례 보고
이해미,배성하,이수남,이정우,신아영,류시영,이수연,윤문희,한선영,한남익,이영석,유진홍 대한감염학회 2010 감염과 화학요법 Vol.42 No.3
Citrobacter species is a gram-negative bacilli that can cause opportunistic infections in immunocompromised hosts. Citrobacter braakii refers to the genomospecies 6 of the Citrobacter freundii complex. There are no detailed studies on infections caused by this newly identified specific genetic species in Korea. We herein report a case of a patient with hepatocellular carcinoma who, after undergoing transcatheter arterial chemoembolization, developed biloma which later progressed to C.braakii sepsis and did not respond to treatment. To our knowledge, this is the first reported case in Korea on C. braakii infection resulting in septic shock in a patient with malignancy in Korea.
기능적 발목관절 불안정성의 등속성 근력과 균형 및 보행 중에 근활성도와 발바닥압의 평가
이선아 ( Sun-ah Lee ),김아람 ( Ah-ram Kim ),유경태 ( Kyung-tae Yoo ),이호성 ( Ho-seong Lee ) 대한물리의학회 2018 대한물리의학회지 Vol.13 No.3
PURPOSE: The purpose of this study was to investigate and evaluate muscle activity and foot pressure during gait, and isokinetic strength and balance in persons with functional ankle instability (FAI). METHODS: Nine healthy subjects (CON, n=9) without FAI and 11 patients (FAI, n=11) with FAI participated in the study after having been screened with an ankle instability instrument and a balance error scoring system. In addition, FAI was classified as non-involved (FAI-N) or involved (FAI-I), and CON was classified as dominant or nondominant. All subjects were evaluated for isokinetic strength (plantar flexion, dorsiflexion, inversion and eversion of 30°/sec and 60°/sec), balance (static and dynamic), muscle activity (tibialis anterior, peroneus longus and gastrocnemius) and foot pressure (static and dynamic) during gait. RESULTS: Results showed that plantar flexion (p<.05), dorsiflexion (p<.05), inversion (p<.01) and eversion (p<.00) of 60°/sec were significantly decreased in FAI-I compared to those in FAI-N and CON. C 90 of static balance with eyes open (p<.01) and closed (p<.00) were significantly increased in FAI compared to those in CON. Forward position of dynamic balance (p<.01) was significantly decreased in FAI compared to that in CON. Gastrocnemius and peroneus longus of dynamic muscle activity (p<.01), left and right weight distribution of static foot pressure (p<.00) and pressure distribution of dynamic foot pressure (p<.00) were significantly decreased in FAI-I compared to those in FAI-N. CONCLUSION: We demonstrated that ankle strength, balance, muscle activity and foot pressure were significantly correlated with FAI.
Yoo, Yun Joo,Kim, Sun Ah,Bull, Shelley B. Hindawi Publishing Corporation 2015 BioMed research international Vol.2015 No.-
<P>Gene-based analysis of multiple single nucleotide polymorphisms (SNPs) in a gene region is an alternative to single SNP analysis. The multi-bin linear combination test (MLC) proposed in previous studies utilizes the correlation among SNPs within a gene to construct a gene-based global test. SNPs are partitioned into clusters of highly correlated SNPs, and the MLC test statistic quadratically combines linear combination statistics constructed for each cluster. The test has degrees of freedom equal to the number of clusters and can be more powerful than a fully quadratic or fully linear test statistic. In this study, we develop a new SNP clustering algorithm designed to find cliques, which are complete subnetworks of SNPs with all pairwise correlations above a threshold. We evaluate the performance of the MLC test using the clique-based CLQ algorithm versus using the tag-SNP-based LDSelect algorithm. In our numerical power calculations we observed that the two clustering algorithms produce identical clusters about 40~60% of the time, yielding similar power on average. However, because the CLQ algorithm tends to produce smaller clusters with stronger positive correlation, the MLC test is less likely to be affected by the occurrence of opposing signs in the individual SNP effect coefficients.</P>
Tandem Repeats (CCTTT)n in the Promoter of iNOS Gene in Korean Genome
Sun-Ah Baek,Min Yoo 대한의생명과학회 2009 Biomedical Science Letters Vol.15 No.2
Nitric oxide is an important factor to regulate the biochemical reactions in the body such as expansion of blood vessel, neural conduction and antimicrobial activity. There are two forms of nitric oxide synthase and iNOS has attracted most attention because it is involved in the development of diabetes and cardiac disease condition. There are several regulatory sequences in the promoter region of iNOS gene. One of them is (CCTTT)n. It has been reported that the number of tandem repeat of (CCTTT)n varies from population to population. So, we analyzed (CCTTT)n polymorphism in Korean genome for the purpose of comparison. According to our present study Koreans are different from other Asians reported previously because (CCTTT)₁? is the highest incidence as opposed to (CCTTT)₁₂ for other countries. This study should facilitate the understanding of the expression of iNOS gene in different population.