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홍원표,송영석,이근하 중앙대학교 기술과학연구소 2000 기술과학연구소 논문집 Vol.30 No.-
본 연구에서는 연약지반개량공사가 실시된 광양지역을 대상으로 압밀기간동안 개량지반의 물리적, 역학적 변화특성 및 개량효과를 고찰되어 있다. 지반개량전 원지반에서 시료를 채취하고, 모래말뚝 타설직후, 압밀방치중(예상압밀도 50%) 및 압밀완료시(예상압밀도 90%)에도 시료를 채취하여 각각 토질정수를 조사 비교하였다. 그 결과 압밀이 진행되는 동안 지반의 강도는 증가하여, 일축압축강도로 구한 점성토지반의 강도증가율(C_u/P_o)이 0.36이 되었다. 그리고, 일축압축강도로 구한 점성토지반의 강도증가율(C_u/P_o)이 0.36이 되었다. 그리고, 일축압축강도와 함수비는 최대압밀응력에 대하여 유일함수관계를 보이고 있으며, 압밀완료시점(예상압밀도 90%)에서 추정된 비배수전단강도는 측정된 비례수전단강도와 비교적 잘 일치한다. In this study, both physical and mechanical properties of soft grounds are investigated during improvement works of soft grounds in Kwangyang. The properties of soil before ground improvement are compared with the properties of the improved ground after Sand Compaction Pile installation, during consolidation(degree of consolidation 50%), and at the end of consolidation(degree of consolidation 90%). From this result, improvement of the shearing strength of soft grounds can be deserved during consolidation, and the improving rate of shearing strength C_u/P_o is 0.36. The relationship between the shearing strength by unconfined compression tests, consolidation stress and water content shows that both the shearing strength and water content have an unique function relationship. The shearing strength predicted by Rutledge hypothesis shows relatives good agreement with the field strength.
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이권범,박환규,홍석주,김기형 조선대학교 동력자원연구소 1996 動力資源硏究所誌 Vol.18 No.1
In this study, when CFRP lamimates are subjected to static loading by the indentation of steel ball to examine a failure mechanism of lamimates, the fracture surface of interlaminar delamination generated at interfaces is investigated by the scanning electron microscopy (SEM). When orthotropic CFRP laimates stacked with two interface are subjected to static loading, interlaminar delaminations extend from the loading side to delamination edge even at any interface, and the fracture surface fo interlaminar delamination generated at two interfaces is symmertrically formed. In the CFRP laminates, the fracture mechanism sppears mainly to be the mixed mode(modes Ⅰ+Ⅱ), and the ratio of mixed mode varies partially. After the fracture initiates at the interface near the loading side with mode Ⅰ, the mixed mode gradually developes, but the total surface at the opposite plane to the loading side fractures with the mixed mode(modes Ⅰ+Ⅱ). While transverse cracks are generated, the direction of shear stresses reverses itself ar the delaminated surface, clarified by the hackle direction of fracture surface.
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김명호,유문집,유석주,박진영,정홍근,박희곤,문기혁 단국대학교 2000 論文集 Vol.35 No.-
Study Design : Spine fusion with fixation procedure is associated with substantial operative blood loss, which frequently necessitates transfusion. The authors evaluated the safety and efficacy of intraoperative autotransfusion using Cell Saver during spinal surgery. Summary of Literature Review : It has been reported that the contraindications to the use of intraoperative autologous transfusion are malignancy, infection, and gross wound contamination. Objectives : The purpose of this study was to evaluate the safety and efficacy of intraoperative autotransfusion using Cell Saver during spine surgery. Material and Methods : We retrospectively reviewed 62 patients who had operation for lumbosacral spinal stenosis and hypotensive anesthesia. Among them, Group Ⅰwhich received autotrans fusion using Cell Savers included 26 patients with fusion of 2 segments, and Group Ⅱ as control group included 13 patients. Group Ⅲ which received autotransfusion using Cell Savers included 17 patients with function of 3 segments, and Group Ⅳ as control group included 6 patients. We analyzed the amount of intraoperative blood salvage using a Cell Saver, the amount of total homologous transfusion amount, intraoperative blood loss, the amount of postoperative drainage amount and perioperative changes of hemoglobin, hematocrit and platelet count. Results : There was no statistical significance between Cell-Saver group and control group in amount of total homologous transfusion and intraoperative(except in 2 segment of fusion using cell saver: 86.5% increased) & postoperative blood loss(p>0.05). The circulatory balance(amount of intraoperative blood salvage using a Cell Saver plus amount of total homologous transfusion minus amount of total blood loss) was statistical significance between Cell-Saver group and Control group. The Cell-Saver group had positive balance and Control group had negative balance. There were no statistical differance in the evolusion of hemoglobin, hematoocrit and platelet count between Cell-Saver group and Control group(p>0.05). There was no transfusion reaction and thromboembolic disease in all group. Conclusion : In retrospective study, Cell Savers was safe and immediate availability in orthopedic surgery such as spinal surgery. It was effective methods for storing a sufficient volume of blood for spine surgery without affecting the patient's postoperative hemodynamic ststes, too. It was possible to operation without intraoperative homologous blood transfusion in 2 or 3 segment fusion. We may need further study.
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김상수,임동건,이준신,심경석,김홍우,이만근 성균관대학교 1997 학술회의지원논문목록집 Vol.1997 No.-
We investigated grain boundary effect for terrestrial applications of solar cells with low cost, large area, and high efficiency. Grain boundaries are known as potential barriers and recombination centers for the photo generated charge carriers, which make it difficult to achieve a high efficiency cell. To reduce these effects of grain boundarues, we investigated various influencing factors such as thermal treatments various grid patterns selective wet etchings for grain boundarues, buried contact metallizations along grain boundaries, and use of metallic thin films. From the various grid patterns we learned that the series resistance of solar cell reduced open circuit voltage and consequently decreased the cell efficiency. This paper describes the effect of various grid patterns and the employment of metallic thin films for a top electrode.
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Outcomes of Pediatric Liver Transplantation in Korea Using Two National Registries
( Suk Kyun Hong ),( Nam-joon Yi ),( Kyung Chul Yoon ),( Myoung Soo Kim ),( Jae Geun Lee ),( Sanghoon Lee ),( Koo Jeong Kang ),( Shin Hwang ),( Je Ho Ryu ),( Kwangpyo Hong ),( Eui Suh ) 대한간학회 2020 춘·추계 학술대회 (KASL) Vol.2020 No.1
Aims: This retrospective study aimed to evaluate overall survival and the risk factors for mortality among Korean pediatric liver transplantation (LT) patients using data from two national registries: the Korean Network Organ Sharing (KONOS) of the Korea Centers for Disease Control and Prevention and the Korean Organ Transplantation Registry (KOTRY). Methods: Prospectively collected data of 755 (333 male, 422 female) pediatric patients who underwent primary LT (KONOS, February 2000 to December 2015; KOTRY, May 2014 to December 2017) were retrospectively reviewed. Results: The 1-, 5-, 10-, and 15-year survival rates were 90.6%, 86.7%, 85.8%, and 85.5%, respectively, in KONOS, and the 1-month, 3-month, 1-year, and 2-year survival rates were 92.1%, 89.4%, 89.4%, and 87.2%, respectively, in KOTRY. There was no significant difference in survival between the two registries. Multivariate analysis identified that body weight ≥6 kg (P<0.001), biliary atresia as underlying liver disease (P=0.001), and high-volume center (P<0.001) were associated with better survival according to the KONOS database, while hepatic artery complication (P<0.001) was associated with poorer overall survival rates according to the KOTRY database. Conclusions: Long-term pediatric patient survival after LT was satisfactory in this Korean national registry analysis. However, children with risk factors for poor outcomes should be carefully managed after LT.
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Central nervous system blast crisis of chronic myeloid leukemia and treatment with dasatinib
( Hong Suk Park ),( Jinny Park ),( Young Saeng Kim ),( In Geun Park ),( Jun Sik Hong ),( Hee Kyong Ahn ),( Sun Jin Sim ),( Eun Kyoung Joe ),( Dong Bok Shin ),( Jae Hoon Lee ) 대한내과학회 2015 대한내과학회 추계학술대회 Vol.2015 No.1
Chronic myeloid leukemia (CML) is a myeloproliferative disorder driven by the BCR-ABL1. Owing to the high efficacy of imatinib mesylate for CML in chronic phase, the frequency of the blast crisis is greatly reduced. Some CML cases develop extramedullary disease caused by infiltration of blast cells. However, the central nervous system (CNS) as an isolated site of extramedullary blast crisis is rare. Herein, we report case of dasatinib-based maintenance therapy for lymphoid blast crisis of the CNS in a patient with CML who was receiving imatinib mesylate therapy. In July 2012, a 55 years old man was diagnosed with Philadelphia chromosome positive CML in the chronic phase. Immediately, imatinib mesylate administration was initiated. Four months after the diagnosis, he complained of headache. On cerebrospinal fluid (CSF) examination, the CSF had increased number of WBCs (6289/iL); almost all WBCs were lymphoid cells. Brain MRI revealed abnormal leptomeningeal enhancement of the frontal lobes. In addition to a complete hematological, cytogenetic response and evidence of the absence of malignant lymphoblasts in the peripheral blood and bone marrow samples, these findings led to the diagnosis of isolated lymphoid blast crisis in CNS. Immediately, the patient was treated with scheduled intrathecal methotrexate, cerebrospinal radiotherapy and TKI dasatinib. Major molecular response was achieved after 4 months after treatment change, followed by matched related allogeneic peripheral blood SCT. During the course of dasatinib maintenance therapy, several follow-up tests were performed and persistently yielded results indicating complete hematologic, molecular, and cytogenetic responses. The patient was neurological symptom-free for 2 years. In addition, the abnormal enhancement of the frontal lobe observed on the initial brain MRI had disappeared. This report is meaningful of significance as because we used a minimal treatment of intrathecal chemotherapy, radiotherapy, allogeneic peripheral blood SCT and an oral TKI without using cytotoxic chemotherapy such as hyper-CyVAD.
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음식물찌꺼기 소멸효율 재고를 위한 발효균 및 발효 공정 최적화 연구
김영권,홍명표,김명진,홍석일,박명석,김종석,장호근,Kim, Young-Kwon,Hong, Myung-Pyo,Kim, Myung-Jin,Hong, Suk-Il,Park, Myung-Suk,Kim, Jong-Suk,Chang, Ho-Geun 유기성자원학회 1998 유기물자원화 Vol.6 No.2
186종의 후보미생물을 대상으로 우수발효(소멸)균 선발시험을 실시한 결과, Rhizopus sp., Galactomyecs sp., Pichia sp., Hyphopichia sp.로 구성되는 4종의 발효균을 선발하였다. 이들 발효균을 이용한 발효(소멸)공정 시험결과, 내용적 50L의 발효조에 대해서, BIO-CHIP Volume 25-30L, BIO CHIP입도 2.0-6.0mm, 송풍량 200-280L/min, 교반강도 24 rpm, 온도 $30-45^{\circ}C$가 최저 발효조건인 것으로 나타났으며, 이러한 조건에서 1일 1kg의 음식물을 30일간 투입하면서 소멸기를 가동한 결과, 93%의 소멸율을 나타내었다. 소멸기 배출물의 재활용 가치를 평가하기 위하여, 발아율 시험을 실시한 결과, 배출물을 적절하게 희석하여 사용하면, 퇴비로서의 가치가 매우 양호한 것으로 나타났다. For the effective disposal of organic food wastes, we seleted 4 strains of microorganism from 186 microbial candidate via enzyme activity test, salt tolerance, food decomposition rate, stability and safety of strains. The identity of these 4 strains are as follows : Fungi is Rhizopus sp., yeasts are Galactomyces sp., Pichia sp. and Hyphopichia sp., In the 50L fermenter scale, we tested various fermenting factor for the optimization of conditions of food waste decomposition using 4 selected strains. The optimum fomenting conditions were as follows : BIO-CHIP Volume 25-30 L, BIO CHIP size 2.0-6.0mm, air flow 200-280L/min, mixing intensity 2-4rpm, temperature $30-45^{\circ}C$. In these fermenting conditions, the efficiency of decomposition(rate of weight loss of food wastes) were 93%. Also the quality of fermenting output were assayed at the basis of fertilizer, and the results were as good as general compost.
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