http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Induction of heme oxygenase-1 protects against podocyte apoptosis under diabetic conditions
Lee, Sang Choel,Han, Seung Hyeok,Li, Jin Ji,Lee, Sun Ha,Jung, Dong-Sub,Kwak, Seung-Jae,Kim, Seung Hye,Kim, Dong Ki,Yoo, Tae-Hyun,Kim, Jin Hyun,Chang, Se-Ho,Han, Dae Suk,Kang, Shin-Wook International Society of Nephrology 2009 Kidney international Vol.76 No.8
Heme oxygenase-1 (HO-1) is an anti-oxidant enzyme normally upregulated in response to oxidant injury. Here we determined the role of HO-1 in podocyte apoptosis in glomeruli of streptozotocin-treated rats and in immortalized mouse podocytes cultured in media containing normal or high glucose. HO-1 expression, its activity, the ratio of Bax/Bcl-2 protein, and active caspase-3 fragments were all significantly higher in isolated glomeruli of diabetic rats and in high glucose–treated podocytes. These increases were inhibited by zinc protoporphyrin treatment of the rats or by HO-1 siRNA treatment of the podocytes in culture. The number of apoptotic cells was also significantly increased in the glomeruli of diabetic rats and in high glucose–treated podocytes. Inhibition of HO-1 accentuated the increase in apoptotic cells both in vivo and in vitro. Our findings suggest that HO-1 expression protects against podocyte apoptosis under diabetic conditions.
A New Sesame Variety, “Kangbaek” with Disease Resistance, Lodging Tolerence and High Yield
Kang-Bo Shim,Churl-Whan Kang,Suk-Bok Pae,Si-Kyu Lim,Yu-Young Lee,Duck-Yong Suh,Jae-Whan Rho,Jin Song,Dong-Whi Kim,Ho-Young Kim 한국육종학회 2005 한국육종학회지 Vol.37 No.5
A new sesame variety Kangbaek was developed from Yeongnam Agricultural Research Institute in 2004. Cros wasmade by lodging resistant SP9003-3 line to the F1with high yielding capacity, folowed by pedigree selection, yield test and RYT by the sesame breeding team at the National Insti-tute of Crop Science up to 2003. The variety showed higher disease resistance, especially phytophothra disease, and lodging resis-respectively. It's 1000 grains weight was about 2.54 g indicating 0.03 g heavier than that of Yangbaekkae, and it's oil content wasabout 52%. Kangbaek also contained total 7.65mg/g of such lignans as sesamin and sesamolin. The average yield of Kang-baek was 82 kg per 10a at the national-wide regional performance.
(E)-γ-히드록시-α,β-불포화 슬폰과 니트릴의 합성
강석구,전제호 성균관대학교 기초과학연구소 1992 論文集 Vol.43 No.2
β,γ-에폭시슬폰과 β,γ-에폭시느트릴을 -78℃에서 THF를 용매로 LDA를 사용하여 탈 양성자-제거반응을 유도하면 선택적으로(E)-히드록시-α, β-불포화 니트릴을 좋은 수율로 각각 얻을 수 있었다. Deprotection-elimination of β, γ-epoxy sulfone and β, γ-epoxy nitrile with LDA in THF at -78℃ afforded (E)-γ-hydroxy-α, β-unsaturated sulfone and (E)-γ-hydroxy-α, β-unsaturated nitrile in good yields, respectively.
치환된 알킬요드화물 또는 크산테이트 화합물과 에틸 아크릴산 또는 메틸 비닐케톤과의 분자간 라디칼 탄소-탄소 결합형성반응
강석구,박영원,박천호,조일환,오원택 성균관대학교 1992 論文集 Vol.42 No.2
생리활성천연물인 lipoxin A, carpenter bee 페로몬, 뇌염모기 페로몬, exobrevicomin 등의 합성의 주요 키탈 중간체들을 치환된 요드화물 또는 크산테이트 화합물과 에틸아크릴산 또는 메틸비닐케톤과의 분자간 라디칼 탄소-탄소 형성 반응에 의해 합성하였다. The chiral building blocks for the synthesis of biologically active natural products such as lipoxin A, carpenter bee pheromone, mosquito ov-iposition pheromone, and exo-brevicomins were synthesized by intermol-ecular radical C-C bond formation of the appropriate substituted iodides or xanthates with ethyl acrylate or methyl vinyl ketone.
姜錫浩,朴永孝,金珠浩,朱星浩 嶺南大學校 工業技術硏究所 1985 연구보고 Vol.13 No.1
The collection efficiency of the Lapple's standard-type cyclone separator was determined in order to investigate the effects of the particle size of the dust samples, the dust loading, and the air inlet velocity to the cyclone under the ambient conditions. The experimental conditions are in the following ranges; the air inlet velocity; 5 to 14.7 m/s, the particle sizes of the mono-dispersed system; 14 to 280 ㎛, the dust loading; 17.8 to 58.6 g/㎥, respectively. The collection efficiencies determined were compared with those predicted by the semi-empirical equations proposed earlier by Strauss (³) and by Licht et al, (⁴) and those are shown to be increased, as the particle size of the sample dusts and the air inlet velocity increase, respectively. However, the effect of the dust loading in the air could not be recognized, but slightly increased. For the poly-dispersed particulate samples, having a wide particle size distribution, the grade or separation efficiency curve was experimentally determined to specify more exactly the cyclone separation performance, and the result was discussed with the statistical analysis previously worked by Herrmann.(??)
강태규,송평섭,최길수,조용준,강용,최호석,김상돈 한국화학공학회 2002 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.40 No.5
직경이 0.102m이고 높이가 1.0m인 기체-액체 순환 및 삼상 순환유동층 생물반응기의 상승관에서 열전달 특성을 고찰하였다. 기체 및 액체의 유속 그리고 생물막 담체의 체류량이 상승관 내부의 수직 열원과 반응기 사이의 열전달 계수에 미치는 영향을 결정하였다. 기체-액체 순환 반응기에서 열전달 계수는 기체의 유속이 증가함에 따라 증가하였으나 액체 유속의 증가에 따라서는 약간 증가하였다. 삼상 순환유동층 생물반응기에서 열전달 계수는 기체의 유속과 유동 생물막 매체의 체류량이 증가함에 따라 증가하였으나 액체의 유속이 증가함에 따라서는 약간 증가하였다. 본 연구의 실험 범위에서 이들 열전달 계수는 실험 조작 변수의 상관식으로 잘 나타낼 수 있었다. Heat transfer characteristics have been investigated in the riser of gas-liquid circulation and three-phase circulating fluidized-bed bioreactors whose diameter and height are 0.102m and 1.0m, respectively. Effects of gas and liquid velocities and holdup of fluidized biofilm media on the heat transfer coefficient between the immersed vertical heater and the bed have been determined. The heat transfer coefficient in the gas-liquid circulation reactor increases with increasing gas velocity, but increases only slightly with increasing liquid velocity. The h(heat transfer coefficient) value in the three-phase circulating fluidized-bed bioreactor also increases with increasing gas velocity or holdup of fluidized biofilm media, but it increases only slightly with liquid velocity. The value of heat transfer coefficient has been well correlated in terms of operating variables.
강석구,조현성,이재호 성균관대학교 기초과학연구소 1989 論文集 Vol.40 No.2
천연물 합성에서 출발물질로 유용하게 쓰이는 디아세톤 글루코스 헥소퓨라노스고리의 산화와 입체선택적 변형에 관하여 연구하였다. 이 고리의 C-3위치에 있는 히드록시기를 Trifluoroacetic anhydride(TFAA)로 사용하여 케토기로 산화시키는 방법을 연구한 후 얻어진 C-3 위치에 케톤에 대해 Grignard반응과 Wittig반응을 도입하여 퓨라노스고리의 C-3위치에 입체 선택적으로 치환기를 유도하는 방법을 연구하였다. 또한 고리밖의 곁가지의 변형도 아울러 연구하였다. We have studied on the oxidation and the stereoselective modifications of the hexofuranose ring derived from diacetone glucose. We have attempted the method of the oxidation with trifluoroacetic anhydride (TFAA) on the C-3 position of this furanose ring. On the other hand, we have induced the stereoselective substrate on the keto group of the C-3 position. The modifications of the side chain out of the ring have been also studied.
강석구,이성호 성균관대학교 기초과학연구소 1990 論文集 Vol.41 No.1
(+)-Aspicilin은 Lecanora속에 속하는 lichen에서 분리된 거대고리락톤계 항생물질이다. 본 연구에서는 이를 비대칭적으로 합성하기 위해 두 부분의 합성 중간체인 벤질 5-데옥시-2, 3-0-이소프로필리덴-6-요드-α-D-만노시드와 (S)-(+)-9-데신-2-올을 각각 합성하였다. We have studied the synthesis of (+)-aspicilin, a macrolactonic substance which is isolated from a lichen source of the Black forest. As building blocks for enantiocontrolled synthesis of (+) -aspicilin, benzyl 5-deoxy-2. 3-0-isopropylidene-6-iodo-α-Dmannofuranoside and (S)-(+)-9-decyn-2-ol were synthesized.
Cu 촉매하에서 유기주석 화합물과 고분자에 결합된 Iodide의 Cross-Coupling 반응에 관한 연구
강석구,임권호,김재선,윤석근,윤승수 성균관대학교 기초과학연구소 1996 論文集 Vol.47 No.2
The copper iodide-catalyzed cross-coupling of polymer bound aryl iodide with organostannanesin N-methyl-2-pyrrolidone (NMP) was accomplishied smoothly in the presence of NaCl.
姜錫浩,姜善泰 영남대학교 공업기술연구소 1985 연구보고 Vol.13 No.2
The separation efficiency curve of the sand dust in the fibrous air filter was estimated from the particle size data of the sample dust measured by means of the optical microscope. The estimated separation curve was affected by the number of the experimental runs, and by the counted number of the particle images on the microscopic photograghs taken for each experimental run. But, the dust collection and the particle size data measured were not so reproducible that the separation efficiency curves determined were very widely scattered from their mean values.