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      • 신생아 제대혈에 있어서 Alphafetoprotein 치와 Bilirubin 치에 관한 연구

        박영봉,나창수 朝鮮大學校 附設 醫學硏究所 1989 The Medical Journal of Chosun University Vol.14 No.1

        Alpha-fetoprotein(AFP) is a major plasma protein synthesized by the fetal liver, york sac, and gastrointestinal tract. There were many reports that elevated AFP levels in maternal serum and amniotic fluid have been associated with fetal distress and intrauterine fetal death, and recent studies demonstrates a high association between elevated AFP levels in maternal serum and umbilical cord blood and subsequent neonatal jaundice in normal healthy fullterm infants. To investigates the relationship between serum AFP and bilirubin levels of the newborn infants, the authors determind maternal serum and umbilical cord blood AFP concentration in 26 cases of normal healthy fullterm infants and their mothers, The serum AFP levels were measured by the method of enzyme immunoassay(AFP-EIA kit, USA) The results observed are summerized as follows: 1. The mean serum AFP levels of the newborn infants and their mothers were 27227.285ng/㎖ and 161.09ng/㎖, respectively and there was significant correlation between serum AFP levels of the newborn infants and their mothers, (Y= 14.598x+25646.955, r=0.1627, P<0.1627, p<0.005) 2. The mean serum AFP levels of the mothers and mean serum bilinibin levels of the newborn infants were 161.09ng/㎖ and 1.19ng/㎖, respectively and there was significant correlation between serum APP levels of the mothers and serum bilirubin levels of the newborn infants (Y=0.000032x+0.2831, r=0. 272491, P<0.005)

      • KCI등재

        매복된 중절치의 재식

        최수미,이긍호,최영철,박재홍 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

        매복치는 인접치의 이동 및 치근흡수, 악궁의 공간상실, 치성낭종 형성, 부분맹출에 의한 감염, 전위맹출 등 여러 가지 합병증을 유발할 수 있다. 이를 방지하기 위해 매복치의 발육상태,모양,매복된 위치나 각도에 따라 발치, 외과적 노출 및 교정적 견인, 재위치 및 치아이식 등을 시행할 수 있다. 본 증례는 상악 좌측 중절치의 맹출장애를 주소로 본과에 내원한 환아로, 내원 당시 상악 좌측 중절치는 치조골 내에서 정상적인 맹출 경로를 이탈하여 역위 매복되어 있었다. 역위된 정도를 고려했을 때 외과적 견인 및 노출을 이용한 교정적 처치를 수행하기 보다는 재식시키는 것이 바람직할 것으로 판단하였다. 치아를 발거하여 치근 부위의 치낭이 건점함을 확인하고 정상적인 치조와 내로 재식한 후 resin-wire splint로 1주일간 고정하였다. 치아의 생활력이 건전하고 치근형성이 미약하여 치수에 대한 처치는 하지 않았으며 그 후 일년 동안 주기적인 관찰을 시행하여 치근의 성장이 양호함을 확인하였다. 매복된 영구치의 매복된 위치나 각도가 정사 범주에서 지나치게 벗어나 예후가 불확실하더라도 무조건 발치하기보다는 환자와 보호자의 심리적인 면, 저작기능, 심미성 등을 고려하여 더욱 보존적인 시술을 하는 것이 바람직할 것이다. Delayed eruption of a maxillary incisor results in midline shift, the space occupied by adjacent teeth and different levels of alveolar height. Extraction or surgical/orthodontic therapy is the most common treatment for a impacted maxillary incisor. Surgical repositioning provides another option for treatment of this problem. The advantages of this approach include immediate esthetic improvement, use of a single and simplified surgical procedure, simple and short orthodontic therapy, a normal gingival margin and the possibility of the developing root adapting to the new position. Autotransplantation of an immature tooth provides for possible adaptation of the developing root apex to the new position. A root whith an open apex has good chance of pulp revascularization after transplantation.

      • KCI등재

        대학병원 정신과 외래 환자의 약물순응도

        권준수,신성웅,정영미,박경호 大韓神經精神醫學會 1997 신경정신의학 Vol.36 No.3

        Objective : In view of the facts that education about diseases and realization of the need form drugs can improve compliance of the patients, we assessed the knowledge about drugs and medication compliance in psychiatric outpatients. In addition, we investigated factors that influence patients compliance to develop a model of medication compliance. Methods : One-hundred twelve male and eighty female psychiatric outpatient were asked about drug information using questionnaires. We developed a model that predicts medication compliance using chi square tests and multiple regression analysis. Results : More than a half of the patients knew at least one of the names and the effects of the drugs they had taken, but many of them didn't know the side effects of drugs. About eighty percent of the patients showed good compliance. Knowledge of side effects, belief in the benefits of drugs, and level of education could predict medication compliance reliably. Conclusions : Because education level could not be managed by physician, we could enhance compliance through education about drug side effects and benefits of medications.

      • Mg(OH)₂를 이용한 습식탈황에서 폐슬러리 처리특성연구

        김근범,이은덕,박영성,임봉수 大田大學校 環境問題硏究所 1998 환경문제연구소 논문집 Vol.3 No.-

        Properties analyses and treatment characteristics of waste slurry discharged in the wetted flue gas desulfurization process using Mg(OH)₂as a absorbent were investigated. Aeration and coagulation test were carried out to evaluate variation of some factors such as COD, SS, T-N, etc. related to waste slurry treatment. The hydraulic retention time(HRT) and coagulant dosage rate were applied as operating variables in experiment. As experimental results, the reduction effects of COD, SS in aeration test were distinct, due to oxidation of SO₃ and floc, formation of suspended solids. It was also found that the reduction efficiencies of SS and T-P in coagulation test are higher than 90%.

      • KCI등재

        기업 사이버교육 학습자들의 내적통제소재, 조직의 지원, 학습몰입, 학업지속의향 간의 구조적관계 규명

        주영주,김수미,박수영,김은경 이화여자대학교 교육과학연구소 2009 교육과학연구 Vol.40 No.3

        본 연구는 기업 사이버교육생을 대상으로 하여 내적통제소재, 조직의 지원, 학습몰입과 학업지속의향 간의 구조적 관계를 검증하는 것을 목적으로 하였다. 이를 위해 A기업의 2009년 1월 사이버강좌 수강생 447명을 대상으로 연구를 수행하였다. 그 결과 내적통제소재와 조직의 지원은 학습몰입에 직접적인 유의한 영향을 미쳤으며, 내적통제소재와 학습몰입은 학업지속의향에 직접적인 유의한 영향력을 가지는 것으로 나타났다. 또한 학습몰입은 내적통제소재와 학업지속의향, 조직의 지원과 학업지속의향을 매개하는 변수임을 확인하였다. 이와 같은 연구결과는 내적통제소재가 사이버교육 과정의 교수설계와 개발전략을 위해 고려되어야 하는 변수라는 것과, 조직의 지원이 기업 사이버교육의 효과성을 향상시키는데 있어서 중요한 변수라는 것을 시사한다. 이에 본 연구는 성공적인 사이버교육을 위한 학습전략을 제공하는데 있어서 기초적인 토대를 제공하는데 기여할 것으로 기대된다. The purpose of the present study is to verify the structural relationship among internal locus of control, organizational support, flow and learning persistence in Corporate Cyber Education. The subjects were 447 students who participated in A’s corporate cyber courses. A hypothetical model was proposed, which was composed of internal locus of control, organizational support, flow as an extraneous variable, and learning persistence as an endogenous variable. Flow has also been suggested as an intervening endogenous variable. The results of this study through structural equation modeling analysis indicated that both internal locus of control and organizational support significantly affect flow. Also, internal locus of control and flow affected learning persistence significantly. As a result of the Sobel test to examine the significance of the mediation effect, flow was a mediating variable between internal locus of control and learning persistence, organizational support and learning persistence. These results imply that internal locus of control should be considered for the design and development strategies of online courses. Also, organizational support is critical to enhance the effectiveness of corporate cyber education. This study proposes the first step of learning strategies for successful cyber education.

      • Single Nucleotide Primer Extension 기법을 이용한 SNP 연구

        안영욱,예성수,박영홍 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.5

        Single nucleotide polymorphisms(SNPs) are the most frequent type of DNA sequence variation of individuals. They are defined by the presence of two alternative bases at a particular position in a DNA sequence and occur about one per 500-1000bp in the human genome. The recent completion of the first reference sequence of the human genome has provided a basis for comprehensive analysis of sequence variation in man. The identification and dense mapping of SNPs is of considerable significance for association studies of complex diseases, pharmacogenetics, population genetics and physical mapping. Their use as genetic markers is favored by their high abundance, low mutation rate and the easy automation of typing. With the development of ABI Prism 3100 or 3700 system, single nucleotide primer extension, we car get a straightforward and large-scale method for validation of or comparative genotyping of known SNPs and point mutations. In the mini sequencing primer extension reaction, a DNA polymerase is used specifically to extend a primer that anneals immediately adjacent to the nucleotide position to be analyzed with a single labeled nucleoside triphosphate complementary to the nucleotide at the variant site. The reactor allows highly specific detection of point mutations and single nucleotide polymorphisms(SNPs) without direct sequencing. Because all SNPs can be analyzed with high specificity at the same reaction conditions, mini sequencing is a promising reaction principle for multiplex high-throughput genotyping assays. It is also a useful tool for accurate quantitative PCR-based analysis. This review discusses the advanced biotechnique.

      • KCI등재후보

        VDT작업별 정신사회적 스트레스와 근골격계 장애에 관한 연구

        백남종,강종두,주영수,배인근,권호장,박종만,조수헌,김돈규,김재용,최홍렬 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.4

        It has been hypothesized that jobs that have both high psychological demands and low decision latitude("job strain") can lead to musculoskeletal disorder. The objective of this study was to test whether job strain was correlated with the presence of work-related musculoskeletal disorder, especially myofascial pain syndrome(MPS). Information on demographic factors, confounders such as household load and taking care of children or not, and scores for decision latitude, job demand, and social support was obtained by self-administered questionnaire, which had been developed in Korean language, by adopting NIOSH instrument and Extended Karasek Model(16 items). All subjects were also examined by rehabilitation medicine specialists for musculoskeletal disorders. Subjects(n=370) could be categorized into 4 groups, these were, housewives(n=89), shipyard CAD workers(n=89), general female workers(n=79; nurses, insurance counselors, public officials, clerks, etc), and telephone directory assistance operators(n=113). Results from univariate analyses indicated that all demographic factors, all confounders, scores for decision latitude and social support were not associated with the risk of musculoskeletal disorder. However, score for job demand was higher in musculoskeletal disorder cases than others. In subgroup analysis, this association was convinced again, in telephone directory assistance operators. Job strain model showed that the group of telephone directory assistance operators was high-stain group, and OR of musculo skeletal disorder was 2.446(95% C. I. : 1.174, 5.096), when comparing this with the low strain group. In conclusion, job strain is a risk factor for work-related musculoskeletal disorder.

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