좌전하행지 관동맥 개구부위의 망사형의 관(Slotted Tube)스텐트와 나선형 코일(Coil)스텐트 삽입후 단기 및 장기 암상 경과의 비교

박훈기,박성욱,이일수,이상곤,김진우,이근,정상식,이철환,홍명기,김재중,박승정 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

말기신질환을 동반한 다발성 골수종 1예에서 시행된 자가말초혈액 조혈모세포이식

유승민,박정우,이규훈,방수미,안정열,박필환,조은경,신동복,이종호,이재훈 대한조혈모세포이식학회 2002 대한조혈모세포이식학회지 Vol.7 No.2

본 환자는 혈액투석이 요구되는 말기신질환을 동반한 다발성골수종으로 진단받고 VAD 유도요법으로 초기 치료 후 부분관해를 보였으며, melphalan 투여 후 자가말초 조혈모세포이식을 시행하여 심각한 부작용 없이 완전관해를 보이고 그 효과가 1년간 유지되어 이를 보고하는 바이다. Multiple myeloma with monoclonal gammopathy of the lambda light chain, which initially manifested as end-stage renal disease, was diagnosed in a 50-year-old man. Induction chemothery with VAD (vincristine, adriamycin, and dexamethasone) failed to induce a complete response. Complete remission was obtained after high-dose therapy using melphalan (100 mg/m²) followed by autologous peripheral stem cell transplantation. Hemodialysis was performed every day or every other day during induction and high- dose therapy. The adverse events during transplantation consisted of mucositis and neutropenic fever. This case demonstrated that a sustained complete response can be achieved in multiple myeloma complicated by end-stage renal failure using hemodialysis and high-dose chemotherapy without serious toxicity.

Co-60 감마선에 대한 부정형조사면의 조직공중선량비(TAR) 계산

이수용,김채옥,김필수,지영훈 漢陽大學校 基礎科學硏究所 1988 基礎科學論文集 Vol.7 No.-

방사선치료에 사용되는 대표적인 부정형조사면 다섯가지에 대한 각 관심점에서의 선량계산을 위하여 새로 고안한 도표를 사용하여 Co-60감마선에 대한 부정형조사면의 조직공중선량비(TAR)를 계산하였다. 도표를 이용한 계산과 기존의 계산법인 컴퓨터계산법 및 근사법으로 구한 TAR를 측정에 의한 TAR에 비교하여 다음과 같은 결과를 얻었다. 관심점이 방사선속의 중심축상에 있을 때 부정형조사면에서 이들 방법으로 구한 TAR의 대부분은 오차가 1% 이내에서 잘 일치되어 있으며, 축으로부터 벗어난 경우에는 최대 오차가 각각 2.4%,2.3%, 및 8.8% 이었다. 이들 결과로부터 새로 고안한 도표를 이용한 계산법의 정확성을 확인하였다. In order to calculate the dose on each interest point in five types of irregularly shaped fields used commonly in radiotherapy, the tissue-air ratios (TAR) in these fields for Co-60 gamma radiation were calcnlated using the newly devised SAR-chart. The TARS calculated from newly method of using the SAR-chart. computer method and approximation method at the interest point were compared to the TARs obtained from measurement. The result are as follows: In case of the interest points on central axis the calculated TARs in irregularly shaped fields by the above metioned methods were well agreed within the error of 1%, whereas for the interest points on off-axis the calculated TARs were resulted in the maximum errors of 2.4%, 2.3% and 8.8% respectively. From these results, the accuracy of calculation method of using the SAR-chart was comfirmed.

坐劑의 吸收에 關한 硏究(第5報) : Polyvinylpyrrolidone Iodine 坐劑에 대한 粒子度 및 基劑의 影響 The Effect of Different Particle Sizes and Bases on Polyvinylpyrrolidone Iodine Suppositories

李鍾錫,徐成勳,金壽億 慶熙大學校 1990 論文集 Vol.19 No.-

The effect of two different particle sizes and three different of base on preparation of polyvinylpyrrolidone iodine suppositories were studies in this paper. The partcle size of povidone-iodine was divided into two parts(0.074㎛, 0.149㎛) by sieving method. Three types of base used in povidone iodine-suppositories were as follows : witepsol H-15 as a oleogeous base, cacao butter contained 1% of polysorbate 80 as a o/w type emulsified base and macrogols (macrogol 1000 : 1540, 1:4 w/w) as a water soluble base. Suppositories perpared with different particle sizes and base were examined for appearance and dispersion of drug. It was found that the apperance of suppositories with water soluble bases, macrogols, was better in color and dispersion than with the witepsol H-15 and the cacao butter. Each suppositories was tested for 8 weeks under the accelerated conditions(temp : 40。, RH : 75%) and room temperature (temp : 20。±3。, RH : 50±5%). The suppositories prepared with water soluble base were more stable in the content of povidone-iodine than with oleogeous base and o/w type emulsified base. The suppositories with 0.074㎛ of particle size were all the same to the suppositories with 0.149㎛ of particle size.

Langmuir probe를 이용한 플라즈마 진단

이태기,한용진,정재훈,채희백,이수빈,홍진수 순천향대학교 기초과학연구소 1998 순천향자연과학연구 논문집 Vol.4 No.2

The plasma parameters such as temperature and plasma potential was found by the use of a Langmuir probe. It is well known that the properties of the laser-produced plasma plume have an effection those of thin films. Thus, to understand the deposition processes of thin films and to deposit thin films having specific properties it is to necessary to probe the plasma, so we used Langmuir probe. The second harmonic of a Q-switched Nd:YAG laser have 6ns pulse-width and the peak intensity of focused laser beam on the high purity(99.7%) graphite target was nearly ??.

뇌하수체 선종내 출혈의 임상분석

이봉훈,김오룡,김성호,배장호,최병연,조수호 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.5

Methylphenidate 투약에 따른 주의력결핍 과잉운동장애 아동의 정량화 뇌파의 변화

이병대,정성훈,이만기,장수민,백지령,임효덕 대한생물치료정신의학회 2002 생물치료정신의학 Vol.8 No.1

TiAl 합금을 위한 Al-21Ti-23Cr 및 Al-37Ti-12Cr 코팅재료의 장기간 산화특성 평가

이재경,김수현,오명훈,위당문 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.10

Both Al-21Ti-23Cr(L1₂+Cr₂Al) and Al-37Ti-12Cr(γ+TiAlCr) two-phase alloys have been accepted to be the most pertinent coating materials in Al-Ti-Cr alloy system to improve the high-temperature oxidation resistance of TiAl alloy taking into consideration of the oxidation properties, the resistance to thermal stress and the chemical compatibility. The cyclic oxidation tests at 1000℃ and 1200℃ were performed for the specimens coated with both materials of 10 mm thickness, and the breakaway oxidation could be observed although both bulk alloys could form a stable Al₂O₃layer. And it was resulted from depleted Al content in the coating layer due to Al₂O₃oxide growth and interdiffusion with substrate. Considering the decrease of Al content resulting from oxide growth, the Al-21Ti-23Cr coating with higher initial Al content was more effective for oxidation protection of TiAl alloy for long-term service. On the other hand, when the change of Al content due to the interdiffusion with substrate was considered, the Al-37Ti-12Cr coating with smaller compositional gradient with TiAl substrate was more effective than the Al-21Ti-23Cr coating. However, it was confirmed through the cyclic oxidation tests at 1000℃ and 1200℃ that the initial Al content was more important for longer life-time of coating materials than the smaller compositional gradient with substrate. Therefore, the Al-21Ti-23Cr coating would be supposed to be more effective for long-term oxidation resistance of TiAl alloys.

영월 하송리 출토 금속유물 보존처리 및 제작기법 연구

이병훈,고형순,김수기 국립중앙박물관 2019 박물관보존과학 Vol.21 No.-

본 연구는 강원도 영월 하송리 유적에서 출토된 금속유물의 보존처리 과정과 표면 성분분석 결과를 제시하였다. 금동소형풍탁 1점, 풍설 2점, 호리병 형태 소형 청동병 1점을 대상으로 XRF를 이용한 표면 성분분석을 진행하였고, 호리병 형태 소형 청동병은 X-ray를 통한 내부구조관찰을 실시하였다. 금동소형풍탁과 풍설은 같은 위치에서 출토되었으나, 금동소형풍탁은 도금층이 확인되는데 반해, 풍설은 부식층이 표면에 고착되어 가시적으로 확인되지 않았다. 분석결과 금동소형풍탁은 Cu-Sn-Pb 3원계 합금 청동소지에 Au를 수은 아말감으로 도금하여 제작하였음을 확인하였다. 풍설은 소지가 구리이며, 소량의 금성분이 검출되었다. 호리병 형태 소형 청동병은 형태적으로 비슷한 고려시대 화폐인 은병(銀槪)인지 여부를 확인하고자 표면 성분분석과 함께 X-ray 촬영을 실시하였다. X-ray 촬영 결과 저부의 가운데 부분에 작은 구멍을 막았던 것으로 보이는 흔적이 확인되었으며, 전체적인 표면분석 결과에서는 은이 검출되지 않아 은병이 아닌 청동유물임을 알 수 있었다. This study describes the processes undertaken for the conservation treatment of metal artifacts excavated in Hasong-ri, Yeongwol, Gangwon-do and the results of the related surface composition analysis. X-ray fluorescence analysis (XRF) was applied to analyze the surface composition of a small gilt-bronze wind chime, two clappers, and a small gourd-shaped bronze bottle. The gourd-shaped bronze bottle was investigated using radiography to examine its internal structure. The wind chime and clappers were excavated from the same location. A gilt layer was identified on the wind chime, but surface corrosion made it difficult to identify any such layers on the clappers. The element analysis revealed that the wind chime was made of bronze in a Cu-Sn-Pb ternary system and was gilt-plated using mercury amalgam. The clappers were made from copper with a small amount of gold detected, but did not show any evidence of mercury. Since a thick corrosion layer was affixed to the surface of each clapper, it was impossible to identify the surface composition and determine if the clappers had been gilded. It is possible that the gold detected from the clappers was a foreign substance or had detached from the giltbronze wind chime buried alongside them. The small gourd-shaped bronze bottle was investigated through surface element analysis and radiography to verify if it was a type of silver bottle used as currency during the Goryeo dynasty. The radiography photography identified that a small hole in the middle of the base had been stopped up. The general surface analysis did not detect silver, which suggests that the bottle was made of bronze instead and was not one of the silver bottles used as a means of currency.

漢方製劑의 行動藥理學的 硏究 (第5報) : 柏子仁의 中樞抑制作用에 關하여 Central Depressive Action of Thujae Semen

李淑自,徐成勳,金壽億 慶熙大學校 1983 論文集 Vol.12 No.-

The behavioral effects of Thujae semen aqueous extracts which is used to insomnia, neuroses, nervous prostration in oriental medicine were compared with those of chlorpromazine and dizaepam as a comparison drug in mouse and rat. Effects of Thujae semen aqueous extracts on the central nervous depressive action were tested by spontaneous movement activity using photoelectrical method, smoked paper method and open field method, sloped plate method, extension of hypnosis time induced with phenobarbital-Na pentobarbital-Na and defense against convulsive action induced with picrotoxin, strychnine and electroshock. Thujae semen aqueous extracts was found to pharmacologically expect above various action similar to those of chlorpromazine Hcl and diazepam but action of sample was weaker than that of chlorpromazine and diazepam.