서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

가스상 대기오염물질에 의한 종이 기록물의 가속열화 특성 연구

정소윤(So-Yoon Jeong),전수연(Soo-Yeon Jeon),백소라(So-Ra Baek),정현석(Hyun-Seok Jeong),이진희(Jin-Hee Lee),김형진(Hyoung-Jin Kim) 한국펄프·종이공학회 2015 펄프.종이기술 Vol.47 No.4

Paper records were generally degraded by some factors from atmospheric environments, like temperature, relative humidity or air pollutants. In this study, the degradation behavior of paper records by single or mixed gases of NO₂, SO₂, HCHO and TVOC was evaluated. The mechanical, optical and chemical properties of 4 kinds of paper (acid and neutral-based printing paper, traditional Hanji, and filter paper) were directly and indirectly affected by gaseous harmful materials. The brightness and L<SUP>*</SUP> value in all papers were slightly increased by accelerated aging under gaseous HCHO and TVOCs, but highly decreased by conditions under gases NO₂ and SO₂. The optical properties of paper records were most vulnerable in acid-based paper and high stable in filter paper and traditional Hanji by air pollutant degradation. The aging treatments under mixed gas pollutants including NO₂ resulted in decrease of physical, mechanical and optical properties of paper, so it was supposed that the concentration of NO₂ gas would be strictly controlled for optimum indoor air quality management in domestic storage centers for paper records.

대기 중 유해성분(NO₂, SO₂, HCHO)에 의해 열화된 종이의 물리적 특성

백소라(So Ra Beck),정소윤(So Yoon Jeong),정현석(Hyun Suk Jung),이진희(Jin Hee Lee),김형진(Hyoung Jin Kim),김신도(Shin Do Kim) 한국펄프·종이공학회 2014 한국펄프·종이공학회 학술발표논문집 Vol.2014 No.10

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

Depth Jump 시 하지 관절 상해에 관한 운동역학적 분석

소재무,김윤지,이종희,서진희,정연옥,김광기 한국운동역학회 2005 한국운동역학회지 Vol.15 No.1

J. M. SO, Y. J. KIM, J. H. LEE, H. J. SEO, Y. O. CHUNG ? K. K. KIM. The analysis of lower extremities injury on depth jump. Korean Journal of Sport Biomechanics, Vol. 15, No. 1, pp. 127-142, 2005. The purpose of this study was to analysis biomechanics of the lower extremities injury the heights(40cm, 60cm, 80cm) of jump box as performed depth jump motion by 6 females aerobic athletes and 6 non-experience females students. The event of depth jump were set to be drop, landing and jump. The depth jump motions on the force plate were filmed using a digital video cameras, and data were collected through the cinematography and force plate. On the basis of the results analyzed, the conclusions were drawn as follows: 1. The landing time of skill group was shorter than unskill group at 40cm, 60cm drop height during drop-landing-jump phase especially. The landing time of 60cm drop height was significant between two group(p<.05). 2. The peak GRF of sagittal and frontal direction following drop height improve was variety pattern and the peak vertical force of 40cm drop height was significantly(p<.05). 3. The magnitude of peak passive force was not increase to change the drop height. 4. The peak passive forces was significant at 40cm drop height between two groups(p<.05)

Erythrophagocytosis of Lead-Exposed Erythrocytes by Renal Tubular Cells: Possible Role in Lead-Induced Nephrotoxicity

Kwon, So-Youn,Bae, Ok-Nam,Noh, Ji-Yoon,Kim, Keunyoung,Kang, Seojin,Shin, Young-Jun,Lim, Kyung-Min,Chung, Jin-Ho U.S. Dept. of Health, Education, and Welfare, Publ 2015 Environmental health perspectives Vol.123 No.2

<P>Background: Nephrotoxicity associated with lead poisoning has been frequently reported in epidemiological studies, but the underlying mechanisms have not been fully described.</P><P>Objectives: We examined the role of erythrocytes, one of the major lead reservoirs, in lead-associated nephrotoxicity.</P><P>Methods and results: Co-incubation of lead-exposed human erythrocytes with HK-2 human renal proximal tubular cells resulted in renal tubular cytotoxicity, suggesting a role of erythrocytes in lead-induced nephrotoxicity. Morphological and flow cytometric analyses revealed that HK-2 cells actively phagocytized lead-exposed erythrocytes, which was associated with phosphatidylserine (PS) externalization on the erythrocyte membrane and generation of PS-bearing microvesicles. Increased oxidative stress and up-regulation of nephrotoxic biomarkers, such as NGAL, were observed in HK-2 cells undergoing erythrophagocytosis. Moreover, TGF-β, a marker of fibrosis, was also significantly up-regulated. We examined the significance of erythrophagocytosis in lead-induced nephrotoxicity in rats exposed to lead via drinking water for 12 weeks. We observed iron deposition and generation of oxidative stress in renal tissues of lead-exposed rats, as well as the histopathological alterations such as tubulointerstitial lesions, fibrosis, and up-regulation of KIM-1, NGAL, and TGF-β.</P><P>Conclusions: Our data strongly suggest that erythrophagocytosis and subsequent iron deposition in renal tubular cells could significantly enhance nephrotoxicity following lead exposure, providing insight on lead-associated kidney damages.</P><P>Citation: Kwon SY, Bae ON, Noh JY, Kim K, Kang S, Shin YJ, Lim KM, Chung JH. 2015. Erythrophagocytosis of lead-exposed erythrocytes by renal tubular cells: possible role in lead-induced nephrotoxicity. Environ Health Perspect 123:120–127; http://dx.doi.org/10.1289/ehp.1408094</P>

Diclofenac sodium 으로 인한 Nicolau 증후군 1예

김소진,강정대,윤녕훈,박석돈 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.3

Nicolau syndrome is defined as local cutaneous and sometimes muscular necrosis observed at the injection site of intramuscular preparations. It is characterized by severe pain immediately after the injection and variable degrees of skin necrosis. The only treatment is conservative. A 46-year-old man presented with painful skin necrosis on his buttock after the injection of diclofenac sodium. Histopathologic examination showed necrosis of the epidermis and upper 2/3 of the dermis. The lesion was treated conservatively with topical antibiotic ointment. We report a rare case of Nicolau syndrome due to dicolfenac sodium. (Korean J Dermatol 2004;42(3):370~372)

입원 정신질환자들의 수면의 질과 관련요인에 관한 연구

김명주,윤혜은,박연주,류소연 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

본 연구는 입원 정신질환자들의 생활습관과 수면의 질과의 관련요인을 알아보고자 시도되었다. 전남 나주시 국립나주병원 개방병동에 입원한 정신질환자 154명을 대상으로 2008년 7월 17일부터 7월 25일까지 인구사회학적 특성, 임상적 특성, 입원 생활습관, 입원병력특성 등을 설문지 및 병록지로 조사하였으며, Leeds Sleep Evaluation Questionnaire(LSEQ) 변형도구를 이용하여 수면의 질을 측정하였다. 입원 정신질환자들의 수면의 질 점수는 17.53±5.03점이었으며, 단순분석상에서 수면의 질은 인구사회학적 특성 등과는 관련이 없었다. 그러나 다중회귀분석 결과 과체중군에서, 입원횟수가 많을수록, 통증 정도가 심할수록 수면의 질은 나빴다. 반면, 수면제를 복용한 사람이 복용하지 않은 사람에 비해 수면의 질이 좋았다. 생활습관과 수면의 질과 유의한 차이가 없었던 것은 입원이라는 동일 환경의 한계 때문이라고 생각된다. 이상의 결과로 볼 때 입원 정신질환자들의 수면의 질을 높이기 위해서는 수면제 복용의 약물치료와 함께 체중조절을 고려하고, 통증에 대한 적극적인 대처가 이루어져야 할 것으로 생각된다. Objectives : This study was performed to identify the relations between daily habits and quality of sleep of the psychiatric inpatients. Methods: We interviewed 154 the psychiatric inpatients of open ward in Naju national hospital, Chonnam Naju, from July 17, 2008 to July 25 of the same year. Data was collected using disease records and a questionnaire about socio- demographic characteristics, clinical characteristics, habits in hospital, and characteristics in history of hospitalization. And we measured the quality of sleep using the subjective sleep questionnaire modified from Leeds Sleep Evaluation Questionnaire (LSEQ). Results: The scores of quality of sleep of inpatients were 17.53±5.03. Quality of sleep had no statistically significant relationship with various characteristics in the simple analysis. However, as a result of the multiple regression analysis, the sleep quality of the overweight group was low, and the higher frequency of hospitalization and more pain they had, the worse sleep quality was. However, the sleep quality of those who took hypnotics was higher than that of those who did not. Conclusions: This study suggests that there was no significant difference between daily habits in the hospital and the sleep quality because of limits to the same environment of being in hospital. Based on the results above, in order to enhance the sleep quality of the psychiatric inpatients, we should consider both medication which takes hypnotics and weight control and actively deal with the pain.

보육교사의 아동학대 인식과 신고의무에 대한 태도

김소연,윤혜미 충북대학교 교육 ·생활연구소 생활과학연구센터 2003 생활과학연구논총 Vol.7 No.1

The purpose of this study was to find out the perception of child abuse and attitudes toward reporting among educare center teachers who were specified as the mandatory reporters of child abuse in Child Welfare Law amended in 2000. The subjects of this study were 312 preschool teachers, 231 from urban and 81 from rural area, Self-administered social survey method was employed. The data were analyzed by frequency, percentage, mean(M), standard deviation(SD), t-test, Chi-Square, Person correlation using SPSSWIN program. The results are as follow ; (1) Educare center teachers were highly perceptive of child abuse and quite alert to the occurrence of child abuse. Preschool teachers in the rural area tended to experience higher number of child abuse occurrence than those who in the urban area. (2) Significantly low reporting rate was observed. While 29.8% of educare center teachers had experiences of child abuse observance, only two teachers among them had reported to the authority. The reasons appeared that the most of educare center teachers are not aware of the proper timing for reporting and they don't have the correct information concerning child abuse reporting. Only 26.9% of the subjects, answered that they would report the child abuse cases to the proper authority. It was shown that the child abuse reporting behavior was affected by what happenes after reporting and the extent of their perception of seriousness of the child abuse. It was found that they had not had any formal educational opportunity on the subject of child abuse and reporting, Most of the subjects indicated the need for frequent on-the-job training and workshops on the issue.

양측성 이중성 대상포진 (herpes zoster duplex bilateralis) 1예

김소진,강정대,윤녕훈,박석돈 대한피부과학회 2004 大韓皮膚科學會誌 Vol.42 No.3

Herpes zoster classically occurs unilaterally within the area of skin innervated by a single sensory ganglion. Simultaneous involvement of two noncontiguous dermatomes in very rare and it has been referred to as zoster duplex unilateralis of bilateralis, depending whether one or both halves of the body are involved. A 47-year-old woman presented with painful grouped vesicles on the right chest and the left lower back. The tzanck smear and the skin biopsy were consistent with herpetic infection. She was treated with intavenous acyclovir without any significant complications. We report a rare case of zoster duplex bilateralis. (Korean J Dermatol 2004;42(3):367~369)