스마트폰 부재와 분실을 대비한 어플리케이션

조시현;문상수;김기환;도민균;서재현;김태공 인제대학교 2012 仁濟論叢 Vol.27 No.1

Recently, as the Smart Phone is rapidly disseminated worldwide, it is emerging as an important digital communication media changing the communication types of users. We use the Smart Phone in all aspect of daily life besides communication. The Smart Phone is indispensible tool that has a great ripple effect on our daily life. Therefore, if the Smart Phone users lose or do not bring their phones, they were troubled. In this paper, we make users available to use the Smart Phone, even if they lose or do not bring their phones. To do this end, we develop features that search the phone in case of not knowing where it is, that contact another phone in case of not bringing their phone, that lock the phone in case of losing it. We expect these features promote a expansion and a vitality of the Smart Phone market.

처분장근처에서 침식에 의한 Sr 화학종의 평형

조윤정,김성현,이인화,김시욱,고문주,박성규,이범규 조선대학교 환경공해연구소 2000 環境公害硏究 Vol.16 No.1

Leaching and adsorption equilibria of Sr Chemical Species from the near field of a repository has been studied in solidified cement with Fe and oxidized Fe. The absorption percent, Ads %, and distribution coefficient, K_(d) were calculated using equilibrium concentration to predict the extent of leaching and adsorption. In the mixed aqueous solutions the Ads % increase as Cement(C)/Water(W) ratios increase and K_(d) was decreased for Sr. These behaviors were discussed by adsorption and equilibrium of spiked ions. Oxides Fe promoted the adsorption of spiked ions, but pure Fe had no effect. E_(h) values were also estimated and discussed to elucidate oxidation-reduction environment of experimental system.

처분장근처에서 침식에의한 Sr 화학종의 평형

조윤정,김성현,이인화,김시욱,고문주,박성규,이범규 조선대학교 환경연구소 2000 環境硏究 Vol.16 No.1

Leaching and adsorption equilibria of Sr Chemical Species from the near field of a repository has been studied in solidified cement with Fe and oxidized Fe. The absorption percent, Ads %, and distribution coefficient, K_d were calculated using equilibrium concentration to predict the extent of leaching and adsorption. In the mixed aqueous solutions the Ads % increase as Cement(C)/Water(W) ratios increase and K_d was decreased for Sr. These behaviors were discussed by adsorption and equilibrium of spiked ions. Oxides Fe promoted adsorption of spiked ions, but pure Fe had no effect. E_h values were also estimated and discussed to elucidate oxidation-reduction environment of experimental system.

연쇄상구균을 실험감염시킨 넙치치어의 병리조직학적 관찰

조성환,류시윤,김현수,박배근,김덕환,손화영,윤원기,신창호 충남대학교 수의과대학 동물의과학연구소 1999 動物醫科學硏究誌 Vol.7 No.-

Pathological observations were examined after abdominal inoculation in 7∼8㎝ sized flounder (Paralichthys olivaceus) with 1X10^7 cfu/㎖ of Streptococcus faecalis. The infected flounder were clinically observed and weighed a fish body at 0, 5, 10, 15, 20, 25, 30 days post inoculation. In infected group, mortality were 70% and feed efficiency were 7.2%. In non-infected group, mortality were 10% and feed efficiency were 18.2%. Macroscopically, the significant lesions were characterized by protrusions and opacity of the eyes and ulcer of the caudal pecuncle. Histopathologically, the lesions were observed a degeneration. necrosis and inflammatory cells in muscle of the caudal peduncle and a degeneration and necrosis of the rod cells and detached retina from the black pigmented layer

Novel Trials to Control Harmful Algal Blooms in Seawater

Hyun?Jae Shin,Hoon Cho,Un?Sun Jin,Yun?Kyung Park,Si Wouk Kim 한국생물공학회 2010 한국생물공학회 학술대회 Vol.2010 No.10

돼지생식기호흡기 증후군(PRRS) 바이러스 감염시킨 돼지 기관의 병리학적 관찰

조성환,김현수,윤원기,전무형,류시윤,박배근,손화영,김무강 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

The porcine reproductive and respiratory syndrome virus was inoculated into swine tracheal organ culture. The ballooning degeneration of the tracheal ciliated epithelium and a decrease of ciliary activity from the tracheal organs infected with PRRS virus were observed one day post-infection(PI). Tracheal epithelium showed degeneration and focal necrosis 2 days PI. Epithelial necrosis and loss of cilia and epithelial cells became more severe 3 and 4 days PI. An entire loss of cilia and epithelial cells were recognized 4 days PI, however, control tracheal organs were normal during the period of the experiment except a little decrease of ciliary activities with time..

Effects of Phenytoin and Diazepam on the Seizure Activity in the Cortical Dysplasia Animal Models

Kim, Si-Hyung,Choi, In-Sun,Cho, Jin-Hwa,Park, Eun-Ju,Jang, Il-Sung,Choi, Byung-Ju,Kim, Hyun-Jung,Kim, Young-Jin,Nam, Soon-Hyeun The Korean Academy of Oral Biology 2006 International Journal of Oral Biology Vol.31 No.2

Dysplasia-associated seizure disorders are markedly resistant to pharmacological intervention. Relatively little research has been conducted studying the effects of antiepileptic drugs(AEDs) on seizure activity in a rat model of dysplasia. We have used rats exposed to methylazoxymethanol acetate(MAM) in utero, an animal model featuring nodular heterotopia, to investigate the effects of AEDs in the dysplastic brain. Pilocarpine was used to induce acute seizure in MAM-exposed and age-matched vehicle-injucted control animals. Field potential recordings were used to monitor amplitude and numbers population spikes, and paired pulse inhibition in response to stimulation of commissural pathway. Two commonly used AEDs were tested: diazepam 5, 2.5mg/kg;phenytoin 40, 60mg/kg. Diazepam(DZP) and phenytoin(PHT) reduced the amplitude of population spike in control and MAM-exposed rats. However, the amplitude of population spike was nearly eliminated in control rats as compared to the MAM-exposed rats. Pharmaco-resistance was tested by measuring seizure latencies in awake rats after pilocarpine administration(320mg/kg, i.p.) with and without pretreatment with AEDs. Pre-treatment with PHT 60 mg prolonged seizure latency in control rats, but not in MAM-exposed animals. The main findings of this study are that acute seizures initiated in MAM-exposed rats are relatively resistant to standard AEDs assessed in vivo. These data suggest that animal model with cortical dysplasia can be used to screen the effects of potential AEDs.

조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

사연 및 동판저수지의 식물성 플랑크톤에 관한 연구

강현무,박시섭,이상명,조현아,이진우,이호원 慶南大學校 附設 基礎科學硏究所 1995 硏究論文集 Vol.7 No.-

본 연구는 1994년 2,5,8,11월의 4회에 걸쳐 실시하였다. 조사 결과 동정 분류된 식물성 프랑크톤은 사연호가 6강 126분류군, 동판저수지가 5강 100분류군으로 전체 6강 211분류군이 출현하였다. 월별 종조성은 사연호에서 5월이 50분류군, 8월이 43분류군, 2월이 31분류군 순으로 출현하였다. 동판저수지는 5월이 49분류군, 11월이 27분류군, 2월 25분류군, 8월이 24분류군 순이다. 강별 구성비에서 두 지역모두 녹조강이 가장 많고 다음이 규조강 순이다. 전체 종조성은 사연호는 녹조강 54.3%, 규조강이 25.2%, 유글레나강 7.9%, 남조강 7.1%, 황녹조강 4.7%, 황갈조강 0.8%순이다. 동판저수지의 전출현 종에 대한 종조성은 규조강 51.4%, 녹조강33.9%, 유글레나강 11.0%, 황갈조강 3.7%, 황녹조강 10.9%의 종조성을 나타내었다. 환경요인은 pH의 경우 사연호 8월에 9.28로 가장 높고, DO는 동판 5월이 12.3㎎/ℓ으로 가장 높게 나타났다. 클로로필 a는 사연 2월이 13.1㎎/㎥로 가장 높으며, 부유물질은 동판저수지 5월에 85.0㎎/ℓ으로 가장 높았다. Phytoplankton flora of Sayoun and Tongpan-Reservoirs were studied. A total of 204 taxa (Sayoun-Reservoir, 126 taxa : Tongpan-Reservoir, 100 taxa) were indentified. The Major taxa of two localities was Chlorophyceae 46.7% and Bacillariophyceae 35.1%. As the bloom causing species. Microcystis aeruginosa. Ceratium hirudinella and Peridinium divergens were identified. The chlorophyll a concentration of Tongpan-Reservoir was higher then Sayoun-Reservoir.

곰팡이 오염된 사료를 섭취한 개에서 신부전과 calcium oxalate-like crystal

육현정,손화영,류시윤,조성환 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

In March and July 2004, 2-year-old female Yorkshire Terrier and 7-year-old female Shih-Tzu were referred to the College of Veterinary Medicine, Chungnam National University. Clinically, two dogs showed anorexia, vomiting and emaciation. The signs had occurred after the dogs were fed diets infected with oxalate-producing fungi. At necropsy, Shih Tzu had severe renal damage with the green-yellowish colored uroliths in the renal pelvis and the both kidneys were extremely reduced in sizes. Microscopically, Yorkshire Terrier had acute nephritis contained necrotized and degenerated tubular epithelial cells in cortex. Numerous calcium oxalate-like crystals were infiltrated into most tubules, especially the proximal convoluted tubules. Shih Tzu showed chronic nephritis with nephrosclerosis displaced by fibrous connective tissue in most areas. The glomeruli had undergone all stages of variation such as degeneration and fibrosis.