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      • KCI등재

        Exploring Information Warfare Strategies during the Russia–Ukraine War on Twitter

        Shu–Min Hou,Wen-Cheng Fu,Shao–Yi Lai 한국국방연구원 2023 The Korean Journal of Defense Analysis Vol.35 No.1

        Twitter, one of the mainstream social media platforms, has played a significant role in strategic communication and public diplomacy. Using tweets during the 2022 Russia–Ukraine war period as a case study, the researchers aim to build a pipeline that automatically detects information manipulation. Artificial intelligence and machine learning technology are adopted to target certain coordinated groups of people, and how they manipulate online public opinion internationally via social media platforms by retweeting identical tweets between members within the groups and even with their own tweets. With the large number of tweets posted and retweeted by the coordinated groups, their intended content will appear in the news feeds of normal users. This study maps an approach to future warfare that social media is becoming a vital part of information warfare to influence the results of conflict and regional relationships. The researchers argue that the government should consider taking countermeasures: 1) Set up legislation regarding media platforms and cooperate with social media companies to monitor manipulating behaviors. 2) Establish a model to orchestrate inter-agency defensive strategies. 3) Increase people’s media literacy to allow them to be aware of manipulative and collaborative behavior and decrease their likeliness to spread fake/manipulated information online unintentionally. Also, similar research can be adapted to different regional conflicts.

      • KCI등재

        Heat dissipation in high-power semiconductor lasers with heat pipe cooling system

        Shili Shu,Guanyu Hou,Lijie Wang,Sicong Tian,Leonid L. Vassiliev,Cunzhu Tong 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.6

        This study focuses on the application of heat pipes in thermal management for high-power semiconductor lasers. The heat pipe cooling systems are used for heat dissipation in high-power semiconductor lasers. These systems are used instead of water cooling machines to realize a compact and lightweight laser module. The n-shaped heat pipe cooling system, which consists of eight 6 mm copper heat pipes with sintered powder wicks, can easily handle a heat load of up to 73 W from a single-laser unit. The fabricated U-shaped heat pipe cooling system, which consists of ten 12 mm copper heat pipes with sintered powder wicks, can easily handle a heat load of up to 300 W from five laser units. The optical power of the multi-laser module cooled by the U-shaped heat pipe cooling system reaches 210 W. These results indicate that high-power semiconductor lasers can be cooled using heat pipe cooling systems instead of water cooling machines.

      • Equivocal Association of RAD51 Polymorphisms with Risk of Esophageal Squamous Cell Carcinoma in a Chinese Population

        Zhang, Shu-Xiang,Yang, Shan,Xu, Chang-Qing,Hou, Rui-Ping,Zhang, Chuan-Zhen,Xu, Cui-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        Aim: To study the contribution of genetic variation in RAD51 to risk of esophageal squamous cell carcinoma (ESCC). Methods: Three single nucleotide polymorphisms (SNPs) in RAD51 (rs1801320, rs4144242 and rs4417527) were genotyped in 316 ESCC patients and 316 healthy controls in Anyang area of China using PCR-RFLP (polymerase chain reaction-restriction fragment length polymorphism). Demographic variables between cases and controls were statistically compared by T test and Chi-square test. Hardy-Weinberg equilibrium was evaluated by the Chi-square test. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to measure any association with ESCC. Haplotype frequencies were estimated by Phase 2.1. Result: The genotype frequencies of rs1801320, rs4144242 and rs4417527 in patients with ESCC demonstrated no significant differences from those in control group (P>0.05). When the haplotypes of these three SNPs were constructed and their relationships with ESCC risk investigated, however, CGG was observed to increase the risk (P=0.020, OR=2.289). Conclusions: There was no association between the three SNPs of RAD51 and ESCC susceptibility in our Chinese population. However, the CGG haplotype might be a risk factor.

      • KCI등재

        Multiple-copy-gene integration on chromosome of Escherichia coli for beta-galactosidase production

        Shao-Yi Hou,Hsing-Ta Chen,Ming-Shu Lin 한국화학공학회 2008 Korean Journal of Chemical Engineering Vol.25 No.5

        Recombinant E. coli strains with 1-3 copies of lacZ genes on their chromosomes were constructed and their β-galactosidase (β-gal) expressions were examined. Serial dilution cultures were used to analyze the long-term genetic stability of the recombinant lacZ genes of the chromosomal or plasmid expression system. The strain with a 3-copy lacZ on the chromosome has a sustainable β-gal expression through 60 hours. However, the β-gal activity of the plasmid expression system lasted less than 36 hours under a no selection condition. Obviously, the genetic stability of the chromosomal expression system demonstrated in this study is better than that of the plasmid expression system under nonselective condition, such as a medium without antibiotics. The results demonstrated that the strains with a multiple-copy-gene on the chromosome are useful for protein production in industrial repeated fed-batch fermentation.

      • KCI등재

        The Intrinsic Relation between the Hydrogel Structure and In Vivo Performance of Hyaluronic Acid Dermal Fillers: A Comparative Study of Four Typical Dermal Fillers

        Zhou Weiwei,Hou Shuai,Deng Shu,Peng Yang,Fu Wei,Zhou Yang,Yang Jie,Peng Cheng 한국조직공학과 재생의학회 2023 조직공학과 재생의학 Vol.20 No.3

        BACKGROUND: Hyaluronic acid dermal fillers are composed of cross-linked viscoelastic particles with high biocompatibility. The performance of the fillers is determined by the viscoelastic properties of particles and the connecting force between particles. However, the relationships among the properties of fillers, the interaction of the gels and the surrounding tissue are not clear enough. METHOD: Four kinds of typical dermal filler were selected in this research to reveal the interaction between the gels and cells. A series of analytical tools was applied to characterize the structure and physicochemical properties of the gel, as well as observing their interaction with the surrounding tissues in vivo and discussing their internal mechanism. RESULT: The large particles internal the gel and the high rheological properties endow the Restylane2 with excellent support. However, these large-size particles have a significant impact on the metabolism of the local tissue surrounding the gel. Juve´derm3 present gel integrity with the high cohesiveness and superior support. The rational matching of large and small particles provides the Juve´derm3 with supporting capacity and excellent biological performance. Ifresh is characterized by small-size particles, moderate cohesiveness, good integrity, lower viscoelasticity and the superior cellular activity located the surrounding tissues. Cryohyaluron has high cohesion and medium particle size and it is prominent in cell behaviors involving localized tissues. Specific macroporous structure in the gel may facilitate the nutrients delivering and removing the waste. CONCLUSION: It’s necessary to make the filler both sufficient support and biocompatibility through the rational matching of particle sizes and rheological properties. Gels with macroporous structured particle showed an advantage in this area by providing a space inside the particle.

      • SCISCIESCOPUS

        Electroweak baryogenesis driven by extra top Yukawa couplings

        Fuyuto, Kaori,Hou, Wei-Shu,Senaha, Eibun North-Holland Pub. Co 2018 Physics letters. Section B Vol.776 No.-

        <P><B>Abstract</B></P> <P>We study electroweak baryogenesis driven by the top quark in a general two Higgs doublet model with flavor-changing Yukawa couplings, keeping the Higgs potential <I>CP</I> invariant. With Higgs sector couplings and the additional top Yukawa coupling <SUB> ρ t t </SUB> all of O (1), one naturally has sizable <I>CP</I> violation that fuels the cosmic baryon asymmetry. Even if <SUB> ρ t t </SUB> vanishes, the favor-changing coupling <SUB> ρ t c </SUB> can still lead to successful baryogenesis. Phenomenological consequences such as t → c h , τ → μ γ electron electric dipole moment, h → γ γ , and <I>hhh</I> coupling are discussed.</P>

      • The MTHFR C677T Polymorphism and Risk of Acute Lymphoblastic Leukemia: an Updated Meta-analysis Based on 37 Case-control Studies

        Jiang, Yuan,Hou, Jing,Zhang, Qiang,Jia, Shu-Ting,Wang, Bo-Yuan,Zhang, Ji-Hong,Tang, Wen-Ru,Luo, Ying Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.11

        Background: The C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) has been associated with acute lymphoblastic leukemia (ALL). However, results were conflicting. The aim of this study was to quantitatively summarize the evidence for the MTHFRC677T polymorphism and ALL risk. Methods: Electronic searches of PubMed and the Chinese Biomedicine database were conducted to select case-control studies containing available genotype frequencies of C677T and the odds ratio (OR) with 95% confidence interval (CI) was used to assess the strength of any association. Results: Case-control studies including 6,371 cases and 10,850 controls were identified. The meta-analysis stratified by ethnicity showed that individuals with the homozygous TT genotype had decreased risk of ALL (OR= 0.776, 95% CI: 0.687~0.877, p< 0.001) in Caucasians (OR= 0.715, 95% CI: 0.655~0.781, p= 0.000). However, results among Asians (OR=0.711, 95% CI: 0.591~1.005, p= 0.055) and others (OR=0.913, 95% CI: 0.656~1.271, p= 0. 590) did not suggest an association. A symmetric funnel plot, the Egger's test (P=0.093), and the Begg- test (P=0.072) were all suggestive of the lack of publication bias. Conclusion: This meta-analysis supports the idea that the MTHFR C677T genotype is associated with risk of ALL in Caucasians. To draw comprehensive and true conclusions, further prospective studies with larger numbers of participants worldwide are needed to examine associations between the MTHFRC677T polymorphism and ALL.

      • SCIESCOPUSKCI등재

        Case Reports : Paroxysmal Supraventricular Tachycardia in an Infant with Hand, Foot, and Mouth Disease

        ( Peng Hu ),( Shu Hou ),( Peng Fei Du ),( Jia Bin Li ),( Ying Ye ) 대한피부과학회 2012 Annals of Dermatology Vol.24 No.2

        An 11-month-old male infant was admitted to our hospital with fever, fussiness, poor feeding, vomiting, and tachypnea for two days prior. Physical examination revealed sporadic papules and vesicles occurring on his hands, feet, face, and perianal mucosa. Enterovirus 71 was identified from both throat swab and vesicle fluid using virus isolation techniques. The patient`s heart rate fluctuated in a very narrow range from 180~210/beats/min regardless of his physiologic state. An electrocardiogram showed P-waves buried within or occurring just after regular, narrow, QRS complexes. The patient was diagnosed as having hand, foot, and mouth disease in combination with paroxysmal supraventricular tachycardia (PSVT). The child recovered well with symptomatic treatment, including intravenous administration of acyclovir, glucocorticoids, immunoglobulin, adenosine, and sotalol. PSVT was terminated within 36 hours of hospitalization. The skin lesions became crusted on the third day, and then proceeded to heal spontaneously. Here we report on this unusual case and review the associated literature. (Ann Dermatol 24(2) 200∼202, 2012)

      • All-trans-retinoic Acid Promotes Iodine Uptake Via Up-regulating the Sodium Iodide Symporter in Medullary Thyroid Cancer Stem Cells

        Tang, Min,Hou, Yan-Li,Kang, Qiang-Qiang,Chen, Xing-Yue,Duan, Li-Qun,Shu, Jin,Li, Shao-Lin,Hu, Xiao-Li,Peng, Zhi-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4

        Recently, the main therapy of medullary thyroid cancer (MTC) is surgical, but by which way there is a poor prognosis with a mean survival of only 5 years. In some cases, some researchers found that it is the medullary thyroid cancer stem cells (MTCSCs) that cause metastasis and recurrence. This study aimed to eradicate MTCSCs through administration of all-trans-retinoic acid (ATRA). Here we demonstrate that MTCSCs possess stemlike properties in serum-free medium. The ABCG2, OCT4 and sodium iodide symporter (NIS) were changed by ATRA. Additionally, we found that ATRA can increase the expression of NIS in vivo. All the data suggested that ATRA could increase the iodine uptake of MTCSCs through NIS.

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