Red Number 104호를 포함한 치면세균막 착색정제의 적정 색소함량 및 저작도포시간에 관한 연구

신승철,서현석,류현,장연수,변계영 대한구강보건학회 2003 大韓口腔保健學會誌 Vol.27 No.1

The authors have examined the PHP index, in order to choose the optimum concentration, calivary flow volume and chewing time for Red-Plaque tablets, one of the newly developed disclosing agent for dental plaque. 4 kinds of tablets as 0.5㎎ of Red No.104, 1.0㎎, 2.0㎎ and 5.0㎎ were produced and 30 adults volunteers were selected for clinical experiments. PHP index were checked for extracted tooth of lateral incisor with artificial plaque and dyeing with various concentration of Red-Plaque, as well as for volungeerss 'teeth. Obtained date were analysed and compared. 1. Carbohydrate and protein were contained in dental plaque. 2. 2.0㎎/250㎎ to 5.0㎎/250㎎ of Red 104 contained Red-Plaque tablets were recommended to use checking the dental plaque clinically. 3. It needed more than 1 minutes chewing for disclosing the dental plaque enough, with a 250㎎ Red-Plaque tablet. 4. It was recommended that 2㎖ to 5㎖ volume saliva were needed to dissolve a Red-Plaque tablet of 250㎎ for 1 minute's chewing.

용인 안성지구 산사태와 파괴 형상에 관한 연구

신승목,김상규,장연수 동국대학교 대학원 1993 大學院硏究論集-東國大學校 大學院 Vol.23 No.-

본 논문에는 1991년 7월의 집중호우로 인해 많은 산사태가 발생한 용인·안성지역의 산사태 현장을 방문 조사를 실시한 결과를 토대로 우리나라의 산사태 발생요인과 파괴형상을 규명하였다. 표본지구의 지질암은 풍화된 편마암 및 편암이 주종을 이루고 주요 사면파괴형태는 평행활동파괴 및 토석류이었다. 평행활동파괴는 표토층이 1m내로 얕고 경사가 30˚이상인 사면의 산복부에서 발생한 반면 토석류는 대체로 길이가 길고 경사가 40˚~50˚로 급경사를 이루는 계곡부에서 발생하였는데 토석류발생이 시작된 산정상부에서는 소규모의 평행 또는 회전활동의 흔적이 발견되었다. 본 지역 식생의 뿌리 깊이는 표토의 두께와 거의 일치하고 파괴면도 표토와 기반암의 경계에서 발생하여 집중호우시 나무하중도 국내 지형 지질에서는 무시못할 요소이며 또한 큰 균열도 유수의 침투로를 제공하여 산사태 발생을 촉진시킨 것으로 판단되었다. This paper investigates the causes of the generation of domestic landslides and their representative failure shapes, based on the results of the reconnaissance of Youngin-Ansung region where enormous number of landslides occurred due to downpour in July, 1991. The geology of the site is mainly weathered schist and gneiss, and the representative failure patterns of the landslides are translational sliding and debris flow. The translational sliding failure is generated at the abdominal region of the mountain, of which the thickness of cover soil is less than 1m and its slope is greater than 30 degrees. On the other hand debris flow is generated in the valleys where their slopes are steep in between 40˚ and 55˚ and the travel distance of debris is quite long. At the summit area where debris flows were initiated, small sized translation or rotational failures were found. The thickness of the vegetation roots in the landslide area consists almost with that of the soil covers, and most failure planes are located at the boundary of cover soil and base rock. Hence, it can be recognized that the surcharge load due to vegetation accompanied with severe downpour can be a significant cause of domestic landslides. The macropores formed at these boundaries can also accelerate the initiation of landslides by accumulating the pore pressure in the pores.

NADPH의 안정화 및 이온토포레시스를 이용한 피부투과

신현택,이승연,오승열 숙명여자대학교 약학연구소 2005 약학논문집-숙명여자대학교 Vol.22 No.-

Nicotinamide Adenine Dinucleotide Phosphate (NADPH) has antioxidant effect in the body and thus decreases the symptoms of senility. The development of a transdermal delivery formulation for NADPH is a very difficult task, due to its rapid decomposition by oxidation, low partition coefficient into stratum corneum, high molecular weight and electrical charge at neutral pH in aqueous solution. The purpose of this work is to test several anti-oxidants as the stabilizing agent for NADPH in the aqueous formulation, and to study the effect of these agents on the in-vitro iontophoretic transport through hairless mouse skin. The stability of NADPH in aqueous solution with/without various antioxidants such as butylated hydroxy toluene (BHT), resveratrol, a-tocopherol and Vitamine C was studied. BHT an a-tocopherol (0.01 % w/w) exhibited minimal stabilizing effect, however resveratrol and vitamine C showed significant stabilizing effect. Stabilizing effect of vitamine C was proportional to the concentration in aqueous solution. Although vitamine C increased the stability ofNADPH significantly, it decreased flux of NADPH in a concentration dependent fashion, therapeutic amount ofNADPH can be delivered through skin using iontophoresis and These results suggest that, in order to develope a efficient iontophoresis formulation, it is important to choose a stabilizing agents which are not only potent in stabilizing effect but also not competitive for the delivery of NADPH.

4년제 간호대학(과) 실습 비 및 실습기자재 표준안 개발을 위한 기초조사연구

신경림,박경숙,안양희,정승교,서연옥 성인간호학회 2003 성인간호학회지 Vol.15 No.2

To describe the states of the laboratory facilities, equipment and expenses for practice in a four-year nursing schools and to analyze mandatory requirements for laboratory facilities and equipment. Method: A descriptive survey research design was used. The participants were 49 of the 4-year nursing schools across the nation. The data were collected by e-mail. The return rate were questionnaires was 63.3%(n=31). Result: In 2001 the total expenses for laboratory practice were 21,865,230won and the average per student was 102,418won. Types of laboratories included single and complex. The mean size for laboratories was 318.7 m^2 and mean size for laboratories for fundamental nursing was 161.1m^2. The range for number of students in a laboratory class was 20-30 for eight universities(30.8%). Among required laboratory equipment, items that were mercury and aneroid sphygmomanometers for children, electronic sphygmomanometers. Bell type fetal stetho-scopes, sheepskin, beds for children, for gynecology, and electronic hilo beds. Among the elective equipment, items that were deficient in 50% of the universities were O^2 tents, and incentive spirometers. The number of items that needs to add to the equipment and 22 for elective equipment. Conclusion: A standardized mandatory list of equipment for laboratory facilities and expenses for practice in 4-year nursing schools needs to be developed.

자기공명영상용 라디오주파수 코일의 제작에 있어서 동조 및 매칭에 영향을 미치는 전기 용량 값들의 실험적 측정

양경승,신용진,김영섭,한재진,이성길,김승국,김영근,지연상 조선대학교 기초과학연구소 2003 自然科學硏究 Vol.26 No.-

Radio frequency coil which is capable of transmit and receive the signal has been used for image production in magnetic resonance imaging(MRI). Tuning and matching characteristic of radio frequency coil is major factor determining the image quality. In experiment the used coil was called a staircase type coil which is simplified the birdcage coil and referred to a simple LC resonant circuit. Because the inductance values of the coils are fixed coil performance was examined by changing of the capacitance values. In this study capacitance values were experimentally determined to increase of-tuning and matching effect in junction of the coil between coil endring and BNC cable to obtain the high quality of image.

랫드에서 신우황청심원의 급성 및 아급성독성시험

오승민,남혜윤,김준수,연제덕,신대희,이진영,박대규,조명행,정규혁 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

The acute and subacute toxicity of New Woohwangchungsimwon(NWCH) which was used l-muscone as substitutive material of musk were investigated in S.D. rats. In intraperitoneal acute toxicity test, rats(Sprague-Dawley, SPF) were injected intraperitoneally with dosages of 0, 540, 750, 1,070, 1,500 and 3,000 ㎎/㎏. Body weights were significantly decreased at 540 ㎎/㎏ dose group in both sexes and abnormal autopsy findings were founded in both sexes at all treated groups. Intraperitoneal LD_50 of NWCH was 812.3 ㎎/㎏ in male and 872.3 ㎎/㎏ in female rats. In the subacute toxicity study, NWCH was administrated orally to both sexes of rats for 4 weeks as several doses(0, 320, 800 and 2,000 ㎎/㎏). There were neither dead animals nor significant changes of body weights during the experimental period. In addition, no differences were found between control and treated groups in clinical signs, urinalysis, hematology, serum biochemical analysis, and other findings. Above data strongly suggest that no observed adverse effect level of NWCH might be over 2,000 ㎎/㎏/day in this study.

대학신입생들의 구강상태 인식도와 상대구강진료필요도에 관한 상관관계 조사연구

원상연,신승철,김선영 단국대학교 치과대학 예방치과 1998 예방치과 세미나집 Vol.- No.12

The purpose of this study was to detemine toe correlation between the awareness and the status of their won oral diseases. A questionnaire survey form was desinged to determine the awareness of their won oral diseases and asked aoo of the university freshmen students to fill out the al of questionaries. They were then immediately examined for을 새 determine their status of dental hard tissures by using the WHO criteria. Also determined were the CPITN and the needs for orthodontic as well as prosthodontic treatments. The results were then statistically analyzed to determine the correlation coefficiencies between the awareness and the status of oral diseases by using SPSS statistical package. The results suggested the followings; 1. The correlation coefficiencies between the awareness and the status for number of teeth decayed, missed, and indicated for extractions were 0.18, 0.06 and 0.09 respectively. 2. The correlationg coefficiency between the awareness and the status in treated teeth(F component) and CPITN were 0.622 and 0.10 respectively. 3. The agreement between examiners and examiners on the needs for prosthodontic treatments was 87.31% and their sensitivity and specificity were 47.54% and 88.55% respectively. 4. The agreement between examiners and examinees on the needs for orthodontic treatment was 70.40% and their sensitivity and specificity were 77.27% and 69.71% respectively. Data indicate that a majority of respondents are lacking in the awareness of their own oral disease status. Therefore, it is concluded that a regular oral examination, a regular counselling on oral health status as well as specific oral health education for each individual warranted.

대학 신입생들의 구강상태 인식도와 상대구강진료필요도에 관한 상관관계 조사연구

원상연,신승철,김선영 단국대학교 치과대학 예방치과 1997 예방치과 세미나집 Vol.- No.11

The purpose of this study was to determine the correlation between the awareness and the status of their won oral diseases. A questionnaire survey form was designed to determine the awareness of their won oral diseases and asked aoo of the university freshmen students to fill out the all of questionaries. They were then immediately examined for을 새 determine their status of dental hard tissures by using the WHO criteria. Also determined were the CPITN and the needs for orthodontic as well as prosthodontic treatments. The results were then statistically analyzed to determine the correlation coefficiencies between the awareness and the status of oral diseases by using SPSS statistical package. The results suggested the followings; 1. The correlation coefficiencies between the awareness and the status for number of teeth decayed, missed, and indicated for extractions were 0.18, 0.06 and 0.09 respectively. 2. The correlation coefficiency between the awareness and the status in treated teeth(F component) and CPITN were 0.622 and 0.10 respectively. 3. the agreement between examiners and examinees on the needs for prosthodontic treatments was 87.31% and their sensitivity and specificity were 47.54% and 88.55% respectively. 4. the agreement between examiners and examinees on the needs for orthodontic treatment was 70.40% and their sensitivity and specificity were 77.27% and 60.71% respectively. Data indicate that a majority of respondents are lacking in the awareness of their own oral disease status. Therefore, it is concluded that a regular oral examination, a regular counselling on oral health status as well as specific oral health education for each individual warranted.

직장암 환자의 술 전 병기 결정에 있어서 전산화 단층 촬영의 의의

신용덕,백승언,신연명,오경승 대한대장항문학회 1995 Annals of Coloproctolgy Vol.11 No.3

다발성 간종괴의 형태로 나타난 특발성 과호산구 증후군 치험1예

최승오,연규민,이승민,김순제,왕준호,박형석,이재동,진춘조,이창훈,신현준,김정은 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

Hypereosinophilic syndrome is characterized by persistent blood eosinophilia of 1,500/ul or more in the absence of known causes and multiorgan dysfunction by eosinophil-related tissue damage. In Korea, some cases of hypereosinophilic syndrome with hepatic involvement have been described with prolonged benign clinical courses. Most of them were diffuse or multifocal lesions in imaging studies, and a few case presenting as a single mass has been described. Here we report a case of hypereosinophilic syndrome with hepatic involvement in a 65-year-old man who presented with multifocal mass lesions. By abdominal US and CT scan, multiple, ill-defined nodules were detected in throughout the liver. Liver biopsy revealed severe eosinophilic hepatitis, suggestive of hypereosinophilic syndrome. Hepatic mass lesions improved after steroid administration for several weeks.