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Choi, Yeun Seoung,Lim, Jung Soo,Kwon, Woocheol,Jung, Soon-Hee,Park, Il Hwan,Lee, Myoung Kyu,Lee, Won Yeon,Yong, Suk Joong,Lee, Seok Jeong,Jung, Ye-Ryung,Choi, Jiwon,Choi, Ji Sun,Jeong, Joon Taek,Yoo, The Korean Academy of Tuberculosis and Respiratory 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.
( Yeun Seoung Choi ),( Jung Soo Lim ),( Woocheol Kwon ),( Soon Hee Jung ),( Il Hwan Park ),( Myoung Kyu Lee ),( Won Yeon Lee ),( Suk Joong Yong ),( Seok Jeong Lee ),( Ye Ryung Jung ),( Jiwon Choi ),( 대한결핵 및 호흡기학회 2015 Tuberculosis and Respiratory Diseases Vol.78 No.4
Pulmonary Langerhans cell histiocytosis is an uncommon diffuse cystic lung disease in adults. In rare cases, it can involve extrapulmonary organs and lead to endocrine abnormalities such as central diabetes insipidus. A 42-year-old man presented with polyphagia and polydipsia, as well as a dry cough and dyspnea on exertion. Magnetic resonance imaging of the hypothalamic-pituitary system failed to show the posterior pituitary, which is a typical finding in patients with central diabetes insipidus. This condition was confirmed by a water deprivation test, and the patient was also found to have type 2 diabetes mellitus. Computed tomographic scanning of the lungs revealed multiple, irregularly shaped cystic lesions and small nodules bilaterally, with sparing of the costophrenic angles. Lung biopsy through video-assisted thoracoscopic surgery revealed pulmonary Langerhans cell histiocytosis. On a follow-up visit, only 1 year after the patient had quit smoking, clinical and radiological improvement was significant. Here, we report an uncommon case of pulmonary Langerhans cell histiocytosis that simultaneously presented with diabetes insipidus and diabetes mellitus.
( Ji Sun Choi ),( Myoung Kyu Lee ),( Sang Ha Kim ),( Won Yeon Lee ),( Suk Joong Yong ),( Kye Chul Shin ),( Jiwon Choi ),( Yeun Seoung Choi ),( Jae Ho Seong ),( Ye Ryung Jung ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Limited studies have been identifi ed about nursing and healthcare-associated pneumonia (NHCAP) requiring intensive care unit (ICU) admission. We evaluated the clinical and microbiological characteristics of NHCAP patients admitted to the ICU. Methods: NHCAP was categorized as four groups. Reviewed database included age, gender, comorbid diseases, laboratory data and microbiological Results: The severity of pneumonia was assessed by using the pneumonia severity index (PSI) and CURB-65. The 30-day mortality and duration of ICU stay were evaluated as endpoints Results: Total 428 patients (men, 67.1%) were reviewed. The mean age was 71.2 ± 11.9 year-old. Thirty-day mortality was 25.5%, and duration of ICU stay was 13.8 ± 13.3 days. Mortality (P = 0.349) had no signifi cant difference among four groups although duration of ICU stay (P = 0.008) was signifi cantly longer in group C and D. When we performed multivariate logistic analysis using signifi cant variables, PSI score (OR 1.015 95% CI 1.004-1.026, P = 0.009), serum HCO3- level (OR 0.954 95% CI 0.918-0.993, P = 0.020), duration of ICU stay (OR 0.971 95% CI 0.950-0.993, P = 0.010), multidrug-resistant (MDR) pathogens including ESBL-producing K. pneumoniae (OR 2.688 95% CI 1.237-5.840, P = 0.013) and MDR A. baumannii (OR 3.081 95% CI 1.504-6.311, P = 0.002) were signifi cantly associated with 30-day mortality. Conclusions: ESBL-producing K. pneumoniae and MDR A. baumannii were more often isolated and associated with mortality in NHCAP in ICU patients, therefore these MDR pathogens as well as PSI score should be considered as prognostic factors in NHCAP.
( Myoung Kyu Lee ),( Sang Ha Kim ),( Suk Joong Yong ),( Kye Chul Shin ),( Ye Ryung Jung ),( Jae Ho Seong ),( Yeun Seoung Choi ),( Ji Won Choi ),( Won Yeon Lee ) 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-
Background: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are important causes of hospital admission and mortality. We investigated the clinical features of hospitalized patients with severe AECOPD and evaluated prognostic factors associated the readmission or mortality due to re-exacerbation of COPD within 6 months. Methods: The prospective study was enrolled 314 patients who hospitalized with severe AECOPD. And we collected demographic, clinical and laboratory findings at admission. Lung function was evaluated using the COPD assessment test (CAT) questionnaire, the modified Medical Research Council (mMRC) dyspnea scale, and spirometry in the stable state. Results: The mean age was 72.2 ± 9.4 years (76.4% of male), and the rate of readmission within 6 months was 45.2% and mortality rate was 16.6%. When multivariate analysis was performed by using the significant variables, age (P < 0.001), CAT score (P < 0.001), old pulmonary tuberculosis (P = 0.003), initial PaO2 (P = 0.026), hemoglobin (P = 0.009), albumin (P = 0.005) and CRP at discharge (P < 0.001) were significantly associated with mortality. And also CAT score (P < 0.001), diabetes mellitus (P = 0.030) and CRP at discharge (P = 0.004) were significantly associated with readmission. In receiver operating characteristic curves, CRP at discharge than CAT score showed a good accuracy to predict the mortality. But CAT score showed good accuracy to predict readmission due to severe AECOPD. Conclusions: CRP at discharge as well as CAT score was significantly associated with both mortality and readmission due to AECOPD.
( Myoung Kyu Lee ),( Sang Ha Kim ),( Suk Joong Yong ),( Kye Chul Shin ),( Ye Ryung Jung ),( Jae Ho Seong ),( Yeun Seoung Choi ),( Jiwon Choi ),( Won Yeon Lee ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are important causes of hospital admission and mortality. We investigated the clinical features of hospitalized patients with severe AECOPD and evaluated prognostic factors associated the readmission or mortality due to re-exacerbation of COPD within 6 months. Methods: The prospective study was enrolled 314 patients who hospitalized with severe AECOPD. And we collected demographic, clinical and laboratory findings at admission. Lung function was evaluated using the COPD assessment test (CAT) questionnaire, the modified Medical Research Council (mMRC) dyspnea scale, and spirometry in the stable state. Results: The mean age was 72.2 ± 9.4 years (76.4% of male), and the rate of readmission within 6 months was 45.2% and mortality rate was 16.6%. When multivariate analysis was performed by using the significant variables, age (P < 0.001), CAT score (P < 0.001), old pulmonary tuberculosis (P = 0.003), initial PaO2 (P = 0.026), hemoglobin (P = 0.009), albumin (P = 0.005) and CRP at discharge (P < 0.001) were significantly associated with mortality. And also CAT score (P < 0.001), diabetes mellitus (P = 0.030) and CRP at discharge (P = 0.004) were significantly associated with readmission. In receiver operating characteristic curves, CRP at discharge than CAT score showed a good accuracy to predict the mortality. But CAT score showed good accuracy to predict readmission due to severe AECOPD. Conclusions: CRP at discharge as well as CAT score was significantly associated with both mortality and readmission due to AECOPD.
유비쿼터스 환경에 적합한 VoIP 통화 품질 측정 모델
최승권(Choi Seoung-Kwon),송종명(Song Jong-Myoung),김송영(Kim Song-Young),이병록(Lee Byung-Rok),조용환(Cho Yong-Hwan) 한국콘텐츠학회 2005 한국콘텐츠학회 종합학술대회 논문집 Vol.3 No.1
본 논문에서는 착신효과(Recency Effect)와 버스트 패킷 손실 모델을 적용한 유비쿼터스 환경에 적합한 VoIP 통화품질 측정모델을 제안하였다. 이 측정모델을 통하여, 기존의 모델에서는 구현할 수 없었던 시간의 흐름에 따른 통화품질의 측정이 가능해지며, 또한 버스트 패킷손실 모델을 적용하여, 현재의 네트워크 환경에 부합시켜 이전 모델보다 정교하고 신뢰성 있는 측정을 가능하도록 하게 하였다. In this paper, proposed VoIP call quality Assessment model for Ubiquitous environment that apply the recency Effect and bust packet loss model. It is model that improved E -Model's problems for elaborate and reliable assessment. A new model makes the accurate VoIP call quality assessment possible by applying the burst packet loss and recency effect. Advanced E -model apply bust packet loss model potentialized elaborate and reliable assessment.
최치규(Chi Kyu Choi),강민성(Min Seoung Kang),이개명(Kae Myoung Lee),김상기(Sang Gi Kim),서경수(Kyung Soo Suh),이정용(Jeong Yong Lee),김건호(Kun Ho Kim) 한국진공학회(ASCT) 1995 Applied Science and Convergence Technology Vol.4 No.3
초고진공에서 Si(100)-2×1 기판 위에 Rt를 약 100Å의 두께로 증착한 후 in-situ로 열처리하는 고상에피택셜 성장법으로 PtSi 박막을 형성시켰다. XRD와 XPS 분석 결과 200℃로 열처리한 시료에서는 Pt₃Si, Pt₂Si와 PtSi의 상이 섞여 있었으나 500℃로 열처리한 시료에서는 PtSi의 단일상만 확인되었으며, 형성된 PtSi박막은 주상구조와 판상구조의 이중구조를 나타내었다. 기판 온도를 500℃로 유지하면서 Rt를 증착한 후 750℃에서 열처리한 경우에는 판상구조를 갖는 양질의 PtSi 박막이 에피택셜 성장되었다. HRTEM 분석 결과 에피택셜 성장된 PtSi와 기판 Si(100)의 계면은 RSi[110]//Si[110], RtSi(110)//Si(100)의 정합성을 가졌다. 판상구조를 갖는 PtSi 상의 에피택셜 방향은 기판과 열처리 온도에는 의존하나 열처리 시간에는 무관한 것으로 나타냈다. Solid-phase epitaxial growth of the thin PtSi films were obtained by deposition of a thin Pt(100Å) film on a Si(100)-2×1 substrate in ultra-high vacuum followed by in-situ annealing. X-ray diffraction and X-ray photoelectron spectroscopy showed that Pt₃Si, Pt₂Si and PtSi phases coexisted in the samples annealed at 200℃. However, at 500℃, only the PtSi phase was formed as a bilayered film with a columnar and planar structure. For the Pt(100Å)/Si(100)-2×1 sample which was prepared by deposition of Pt at 500℃ followed by in situ annealing at 750℃ for 10 min, on the other hand, high-quality epitxial PtSi with planar structure was gown. The orientation relationship between the epitaxail PtSi film and the Si(100) substrate from thee HRTEM lattice image is PtSi[110]//Si[110], PtSi(110)//Si(100) without a misorientation angle. It was found out that the epitaxial orientation of the PtSi phase with a planar stucture were mainly depending on the substrate and annealing temperature, not on me annealing time.
사상체질의학(四象體質醫學)과 증치의학(證治醫學)의 비교(比較) 및 상호(相互) 보완(補完) 방안(方案) 연구(硏究)
김명,최나래,오승윤,주종천,Kim, Myoung,Choi, Na-Rae,Oh, Seoung-Yun,Joo, Jong-Cheon 대한한의정보학회 2015 大韓韓醫情報學會誌 Vol.21 No.2
Objectives : Through a comparative study between Sasang constitutional medicine and Syndrome identification and treatment medicine about the theory of diagnosis, the theory of herbal medicine, the theory of prescription, the theory of acupuncture and constitutional medicine to put forward a complementary perfect solution which has good clinical utility. Methods : We compared and sorted out the textbook of Korean Sasang constitutional medicine which named Sasang medicine, and also the textbook of Chinese TCM which was including Basic theory of TCM, Diagnostics of TCM, Science of Chinese materia medica, Pharmacology of traditional Chinese medical formulae, Science of acupuncture and moxibustion, Constitution of TCM, and also related papers. Results : (1) Through a comparative study between Sasang constitutional medicine and Syndrome identification and treatment medicine about diagnosis, herbal medicine, prescription and acupuncture, Sasang constitutional medicine is a medical system which gives priority to balance of organs, when Syndrome identification and treatment medicine is a medical system that gives priority to improve symptom. (2) The prescriptions of Sasang constitutional medicine are used for the treatment of basic pathogenesis in the chronic stage of the disease, which can recover vital qi, when Syndrome identification and treatment medicine are used for the treatment of stage pathogenesis in the acute stage of the disease, which can get rid of pathogenic factors. (3) There are two kind of complementary perfect solution between Sasang constitutional medicine and Syndrome identification and treatment medicine. One perfect complementary medicine is that Sasang constitutional medicine plays a major role when Syndrome identification and treatment medicine plays a supporting role. The other one is that Syndrome identification and treatment medicine plays a major role when Sasang constitutional medicine plays a supporting role. It determined by the usual symptoms and the symptoms now, vital qi and pathogenic factors, symptom and the root cause, acute stage and chronic stage, and the state of pathogenesis. Conclusion : A new perfect complementary medicine can be created which is based on the setting that Sasang constitutional medicine primarily treat the usual symptoms, vital qi, the root cause, chronic stage and basic pathogenesis when Syndrome identification and treatment medicine primarily treat the symptoms now, pathogenic factors, symptom, acute stage and stage pathogenesis.