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김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2
Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.
정승원,한대석,김석중,전문진 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2
Tyrosinase는 식품의 효소적 갈변과 생체내에서 melanin 합성을 촉매하는 효소이다. 식용 가능한 tyrosinase 저해제의 발효생산을 통하여 melanin 합성을 저해하는 효과를 가지는 미백식품 소재를 개발하고자 현재 식품의 제조에 이용되고 있는 안전한 미생물을 대상으로 tyrosinase 저해능이 높은 균주를 선발하고 표고버섯을 주 배지원으로 발효시켜 저해제 생산의 적정조건에 대하여 연구하였다. 발효식품으로부터 분리된 NU-7을 tyrosinase 저해제 생산을 위한 발효균으로 선정하여 tyrosinase 저해제 생산 최적배지 조건을 확인한 결과 glucose가 3~20% 및 ammonium sulfate가 0~0.25%인 범위에서 균체량 증가에 따른 tyrosinase 저해제 생산능의 차이는 나타나지 않았으며, 무기질소원으로 첨가한 ammonium sulfate의 영향은 비교적 낮았다. 한편, 표고버섯(Lentinus edodes, Shiitake) 함량은 저해제 생산과 밀접한 관계를 나타내어 버섯함량(X)에 대한 저해제 생산량(Y)이 Y=-0.96X^2+13.07X+14.43의 상관식을 보였고, R value는 0.96으로 나타나 최적발효 조건을 위한 최소한의 배지는 표고버섯과 glucose 만으로도 가능한 것으로 판단되었다. 표고버섯을 이용한 발효액에서 곰팡이 독소로 알려진 아플라톡신은 검출되지 않았으며 따라서 이를 식용할 수 있는 가능성이 높은 것으로 판단되었다. Tyrosinase is an enzyme which catalyzes an enzymatic browning of some foods and in vivo synthesis of melanin. In order to produce natural and edible inhibitor of the enzyme which is expected to have whitening effect on melanogenesis, a microorganism was selected from fermented foods. It was named as NU-7, and cultured in mushroom (Lentinus edodes, Shiitake) media. Optimal media to produce tyrosinase inhibitor was formulated by varing nitrogen or carbon content. If glucose content was in a range of 3~20% and ammonium sulfate was in a range of 0~0.25%, production of inhibitor was independent of cell mass. Addition of ammonium sulfate as a nitrogen source had little effect on inhibitor production. Production of inhibitor (Y) was proportionally related to shiitake content (X) with a regression equation of Y=-0.96X^2+13.07X+14.43 (R=0.96). These results indicate that shiitake and glucose are necessary for the production of tyrosinase inhibitor. In the analysis of mycotoxin in culture broth, aflatoxin was not detected, suggesting that it would be probably edible.
Jung‑Hun Lee,Min‑Su Park,Hong‑Seon Ahn,Kyung‑Won Park,Jun‑Seok Oh,Seung‑Gyu Jeon,Dong‑Kyu Kim,Jae‑Eon Kim 대한전기학회 2020 Journal of Electrical Engineering & Technology Vol.15 No.4
When large scales DG are connected to the distribution system of unidirectional power currents, bi-directional power currents are formed, making it impossible to use conventional overcurrent protection methods alone to detect and isolate fault sections for ground and short-circuit faults. To solve these problems, this study proposed the method of protection against single-line-ground fault of common neutral line multi-contact local power distribution system using distance relay and directional relay. The proposed protection method was applied to the common neutral multi-ground distribution system to validate the protection against single-line-ground fault through the PSCAD/EMTDC software package and efectively detect and isolate only the zone of single-line-ground fault without malfunctions.
조정태,이석원,남부희 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.B
This paper describes the path planning method in an unknown environment for an autonomous mobile robot equipped with CCD(Charge-Coupled Device) camera. The mobile robot moves along the guideline. The CCD camera is used for the detection of the existence of a guideline. The wavelet transform is used to find the edge of guideline. It is possible for us to do image processing more easily and rapidly by using wavelet transform. We make a fuzzy control rule using image data as an input then determined the position and the navigation of the mobile robot. The center value of guideline is the input of fuzzy logic controller and the steering angle of the mobile robot is the fuzzy controller output. Some actual experiments show that the mobile robot effectively moves to target position by means of the applied fuzzy control.
金正勳,柳輔赫,魏湲錫 弘益大學校 科學技術硏究所 2000 科學技術硏究論文集 Vol.11 No.-
In this paper, portable and vehicle-mounted generators grounding methods of low-voltage systems is compared to each other. Ungrouded system is better for the safety operation than solidly grounding system. Solidly-grounding method causes so high fault current that its safety voltages is lower than the ungrounded method. This paper also determined the magnitude and duration of the pelniissible body current limit and step voltage for the solidly-grounding and ungrounded system.
안동호 상류 운곡천의 이화학적 수질특성과 식물플랑크톤 군집 특성
이중복,이희무,이건주,박정원,박재충,김동걸,권기석 7개 국립대학교 환경연구 논문집 공동발행 위원회 2002 환경연구논문집 Vol.2 No.1
This investigation is about the characteristics of phytoplankton community and physciochemical water quality of specific 6-point the Woon-kog stream system in upsteam of the Andong Lake. DO value was showed over 8.1㎎/L at each site and COD_Mn, BOD, T-N, T-P tend to increase as they stream down and that the existence and dominance of phytoplankton was low and it was difficult to conclude the definite correlation of water quality and phytoplankton community. Finally, it seemed to be desirable that alternatives for pollutional reduction should be made and performed on the basis of the continuous monitoring of the inflow to preserve the Andong Lake.
김석규,장원익,남정칠 東亞大學校建設技術硏究所 2004 硏究論文集 Vol.28 No.1
The the purpose of this study is to propose vegetation management device through analyzing vegetation structure and phytocociological Changes for ten years in Mt. Geumjeong. Eight belt transects of quadrat(20m×20m) were sampled to investigate and analyze the vegetation structure.
신상아에서 후족부 모세 혈액 검사 이후에 발생한 종골 골수염
최장석,김정원 인제대학교 백병원 2002 仁濟醫學 Vol.23 No.3
In neonate, osteomyelitis of the calcaneus is extremely rare and various reports have indicated that it accounts for 3~8% of all bone infections among neonates, infection can result from hematogenous seeding or direct inoculation, as seen in puncture wounds (accidental or for blood sampling), open fracture, degloving injuries. and extension of pressure ulceration. Although direct inoculation has been reported to be the more frequent cause, other reports suggest a hematogenous etiology in the majority. We compared our experience that neonate calcaneal osteomyelitis after hind foot capillary blood sampling for cogenital metabolic deficiencies test and follow up of bilirubin level at Paik Hospital, Inje University, Pusan, Korea to that reported in the literature to determine if the experience at this institution was similar to that previously reported. Additionally, characteristics of the clinical presentation, laboratory investigation, treatment, and outcome were studied to determine if any factors might be helpful in making an earlier diagnosis, improving outcome, or both.
이원석,송준영,김용대,박의수 啓明大學校 醫科大學 1988 계명의대학술지 Vol.7 No.2
We report a case of lupus erythematosus profundus in a 16-year old male. He had multiple pea-nut to bean sized subcutaneous nodules with dark brownish colored overlying skin was present on the upper arm, trunk & other systemic disease. Histologically, deep dermis & subcutaneous layer had dense patch lymphocytic infiltration and homogenized hyaline fat necrosis. Direct immunofluorescene studies showed IgM and C?? deposit on the vessel wall. We treated him with chloroquine and corticosteroid.