Benzoate, m-Toluate, Phenol의 Pseudomonas putida에 의한 생분해

김장규,김석형,김태환,이대광,김남기 成均館大學校 科學技術硏究所 1993 論文集 Vol.44 No.1

It this study, basic data were obtained for the treatment of industrial waste water which includes aromatic compounds. Substrate concentrations used were 100ppm, 500ppm, and 1,000pprn and initial pH's were pH6, pH7, and pH8 in order to obtain the optimum conditions for treating benzoate, m-toluate, and phenol by Pseudomonas putida(KCTC 1644). Durations were 20hrs for 100ppm, 40hrs for 500ppm, and 60hrs for 1,000ppm before the static growth of Pseudomonas putida. 100% of 100ppm benzoate(0.31g cell/1) was biodegraded at pH6, pH7, and pH8 before 20hrs, 52.8% of 500ppm at pH8 in 40hrs, and 27.9% of 1,000ppm at pH8 in 60hrs. The best initial pH was pH8 for the biodegradation and the growth of Pseudomonas putida in benzoate medium. For m-toluate, the best initial pH was also pH8. At this pH, 40.6% of 10Dppm(0.31 cell/1), 21.9% of 500ppm, and 14.1% of 1,000ppm m-toluate were biodegraded respectively in limited time. But for phenol, the best initial pH was pH7. At this point, 9.8% of 100ppm(0.218 cell/1), 7.1% of 500ppm, and 4.7% of 1,000ppm phenol were biodegraded respectively. Therefore, the best carbon source in this experiment was benzoate. Pseudomonas putida was also able to biodegrade m-cresol, p-hydroxybenzoic acid, and benzaldehyde.

고온·고압 처리한 키토산을 이용한 수중의 납 제거에 관한 연구

김동석,이승원,우형택 한국환경과학회 2003 한국환경과학회지 Vol.12 No.12

In order to know the effect of autoclaving on the heavy metal removal using chitosan, lead removal capacities and removal rates by various chitosans in aqueous solution were compared according to the various autoclaving time. The lead removal efficiencies and removal rates by the autoclaved chitosan were found to be on the order of 15 min(98%) > 10 min(95%) > 30 min(83%) > 5 min(53%) > 60 min(47%) > 0 min(22%) chitosan. The molecular weight of chitosan was decreased by the increase of autoclaving time. Therefore, the heavy metal removal capacity was not well correlated to the molecular weight. Langmuir isotherm was well fitted to experimental results of equilibrium adsorption on chitosan. In order to examine the process of lead removal by the autoclaved chitosan, TEMs, SEMs and FT-IR analyses were used. The surface of autoclaved chitosan was much more porous and the lead removal was mainly occurred on the surface of chitosan. The structure of autoclaved chitosan was same as that of controlled chitosan.

S. cerevisiae와 A. pullulans를 이용한 수용액 중의 납 제거에서 온도와 pH의 영향

김동석,서정호,우형택,송승구 대구효성가톨릭대학교 응용과학연구소 1997 응용과학연구논문집 Vol.6 No.1

The environmental factors, temperature and pH, were controlled to investigate the effects on the removal of lead in the solution by S. cerevisiae and A. pullulans. The range of experimental temperature was 20℃∼50℃, and that of Ph was 2.5∼6.5 and 2.5∼12, respectively. The optimum temperature of S. cerevisiae and A. pullulans in the removal of lead was 30℃ and 40℃, respectively. And the initial removal rate of lead by, S. cerevisiae was increased according to the increase of temperatue. The variation of the amounts of lead removal by S. cerevisiae according to the variation of temperature was steeper that by A. pullulans. The optimum pH condition was existed on both of the microorganisms, S. cerevisiae and A. pullulans, in our experimental range and that is 4.5 and 9.0, respectively.

유기용제에 장기간 폭로된 근로자의 정신의학적 기능과 삶의 질

김석재,강순아,유지숙,국승희,윤진상,문재동,이형영 大韓神經精神醫學會 2000 신경정신의학 Vol.39 No.5

연구목적: 본 연구는 Y공단의 제조공정에서 저농도의 유기용제(solvent)에 장기간 노출된 근로자의 정신의학적 기능과 삶의 질을 평가하고자 하였다. 방법: 총 142명의 남성근로자 중 유기용제에 폭로된 군(이하 폭로군) 82명과 폭로되지 않는 군(이하 비폭로군) 60명에게 간이정신진단검사(Symptom Checklist-90-R, SCL-90-R), 인지 및 정신운동성검사 (Critical Flicker Fusion Threshold. CFFT; Choice Reaction Time, CRT;Compensatory Tracking Task, CTT;Digit-Symbol Substitution, DDS) 및 한국판 스미스클라인 비챰 삶의 질 척도(Korean version of the SmithKline Beecham 'Quality of Life' Scale, KvSBQOL) 등을 적용하였다. 두 군간의 비교는 평가치의 평균에 대해 t-검증을 하였고 또한 연령과 학력을 공변인으로한 공변량분석(ANCOVA)을 하였다. 결과: SCL-90-R의 9개 증상 차원과 3개 전체 지표 점수는 두 군이 각각 정상범위였다. 그러나 신체화 (Somatization, SOM), 우울(Depression, DEP), 적대감(Hostility, HOS), 공포불안(Phobic anx-iety, PHOB)의 증상차원과 전체심도지수(Global Severity Index, GSI), 표출증상합계(Positive Symptom Total, PST)의 전체 지표는 폭로군이 비폭로군보다 유의하게 높았다. 인지 및 정신운동성 검사와 삶의 질은 두 군간에 유의한 차이는 없었다. 결론: 이상의 결과는 유기용제가 허용치 이하일지라도 장기간 폭로되는 경우에는 정신의학적 문제를 다소 일으킬 수 있음을 시사하였다. 중심단어:유기용제·근로자·정신건강·정신운동성 기능·삶의 질. Objectives: The aim of this study was to evaluate the psychiatric function and quality of life of the chemical workers who had been exposed to long-term, low-level organic solvents in the Y industrial complex. Method: A total of 144 male workers, of whom 82 were in the exposed group and 60 in the unexposed-control group, were evaluated by using Symptom Checklist-90-R(SCL-90-R), series of neuropsychological tests(critical flicker fusion threshold, CFFT) ; choice reaction time, CRT ; compensatory tracking task, CTT) ; digit symbol substitution test, DSS), and the Korean version of the SmithKline Beecham Quality Of Life scale(KvSBQOL). For the statistical analyses, comparisons of the means of the two groups were performed for each variable with two-tailed t-test as well as ANCOVA including age and education as covariates. Results: For the SCL-90-R, the nine symptom scales and the three global indices were clinically within normal range in both groups. However, the scores on the symptom scales of 'somatization','depression','hostility' and 'phobic anxiety', and those on the global indices of 'global severity index' and 'positive symptom total', were significantly higher in the exposed group than in the unexposed group. In terms of the neuropsychological function and the quality of life, there wes no significant difference between the two groups. Conclusion: These findings suggested that the long-term eposure to mixed organic solvents, even at the low level below the permissible exposure limit, might induce some psychiatric problems. KEY WORDS: Organic solvent·Worker·Mental health·Psychomotor function·Quality of life.

다중회귀모형을 이용한 수완부 골성숙도의 추정에 관한 연구

김경호,유형석,김석현 대한치과교정학회 1997 대한치과교정학회지 Vol.27 No.5

성장의 잠재력에 대한 평가는 개체의 성숙도를 나타내는 여러 생리학적 지표(physiologic indicators)들에 의해 이루어지며 그 중 골성숙도(skeletal maturity)는 성적성숙도(sexual maturity)와 신장의 성장변화와 밀접한 관계가 있는 것으로 알려져 있으나, 치아발육과의 상관관계에 대해선 논란이 많은 실정이다. 그러나 최근의 연구에 의하면 하악견치를 포함한 일부치아의 발육이 골성숙도와 밀접한 관련이 있는 것으로 알려져 있으나, 치아발육과의 상관관계에 대해선 논란이 많은 실정이다. 그러나 최근의 연구에 의하면 하악 견치를 포함한 일부 치아의 발육이 골성숙도와 밀접한 관련이 있는 것으로 보고된 바 있다. 이에, 본 연구에서는 7세에서 15세까지의 한국인 남, 녀 아동 387명의 수완부 방사선 사진과 파노라마 사진을 이용하여 Fishman방법과 Greulich와 Pyle방법에 의해 골성숙도을 평가하였으며 변형된 Demirjiran방법에 의해 치아의 성숙도를 평가하여, 수완부 방사선의 사진의 도움 없이 골성숙도를 추정할수 있는 방법을 구하고자 다중회귀모형을 이용한 수완부 골성숙도의 추정에 관한 연구를 시행하였으며 다음과 같은 결론을 얻었다. 1. 골성숙 지수의 추정을 위한 아래의 다중회귀모형은 84%의 설명력을 나타내며 연대연령, 성별, 하악 견치의 회귀계수는 통계학적 유의성을 보였다. 골성숙지수 = 0.60x 연대연령 -1.67x성별 + 0.88x하악견치 - 0.05x하악 제2대구치 -10.3 2. 골연령의 추정을 위한 아래의 다중회귀모형은 87%의 설명력을 나타내며 연대연령, 성별, 하악 견치의 회귀계수는 통계학적 유의성을 보였다. 골연령 = 0.75x 연대연령 - 0.55x성별 + 0.71x하악 견치 + 0.09x하악 제2대구치- 5.77 (성별: 남자=1, 여자=0., 하악견치, 제2대구치 : 각 발육단계별 평균연령) The evaluation of growth potency can be done with many physiologic indicators. It has been well known that skeletal maturity has a close relation with both sexual maturity somatic maturity, but the correlation between skeletal maturity and dental maturity was believed to be less certain. But, recent studies show that specific teeth, including lower canines, present close correlations with skeletal maturity. So, in this study, we study, we studied hand-wrist X-ray films and orthopantomograms of 387 Korean boys and girls aged from 7 to 15; the purpose was to determine skeletal and dental maturity, and to find out a new method to estimate individual skeletal maturity using multiple-regression model, without the help of hand-wrist X-ray film. As a result of this study, followings were observed. 1. The following multiple-regression model can estimate skeletal maturity index(SMI) with 84% of accuracy, and regression coefficient of chronologic age, sex and lower canine show statistical significance. SMI = 0.60 x chronologic age - 1.67 x sex** + 0.88 x lower canine* - 0.05 x lower 2nd molar* - 10.3 *: mean age corresponding each developing atage, **: male= 1, femal = 0 2. The following multiple-regression model can estimate skeletal age with 87% of accuracy, and regression coefficient of chronologic age, sex and lower canine show statistical significance. Skeletal age = 0.75 x chronologic age - 0.55 x sex** + 0.71 x lower canine* - 0.09 x lower 2nd molar* - 5.77 *: mean age corresponding each developing atage, **: male= 1, femal = 0

폐모세포종 : 1례보고 A Case Report

최영호,서홍주,임영혁,김정중,박성강,이석기,임진수,김은규 조선대학교 2001 The Medical Journal of Chosun University Vol.26 No.2

Pulmonary blastoma is a very rare primary neoplasm of the lung. We experienced a case of pulmonary blastoma in a 40 years old man. The mediobasal segmentectomy of the right lower lobe was performed. The patient was discharge on the postoperative days 6. There is no evidence of recurrence or metastasis on followup study during 7 months period after operation.

3차원 CT 영상을 이용한 정상교합자의 안면 연조직 계측 분석

유형석,한수연,백형선,김기덕 대한치과교정학회 발행 2005 대한치과교정학회지 Vol.35 No.6

최근 들어 3차원 전산화 단층 촬영(CT, Computed Tomography) 영상을 이용한 진단기법의 개발을 위한 연구가 활발히 진행되고 있으며 여러 분야에서 3차원적인 두개악안면 분석의 필요성이 증대되고 있다. 특히 교정 치료나 악교정 수술 후의 결과에 있어서 안면 연조직의 분석은 필수적이라 할 것이다. 본 연구에서는 정상교합을 가진 성인 남자 12명, 성인 여자 11명의 CT 영상을 촬영하여 개인용 컴퓨터 상에서 V works 4.0 프로그램 (Cybermed Inc., Seoul, Korea)으로 3차원 CT 연조직 영상을 재구성한 후에 soft tissue Nasion을 기준 원점으로 하는 3차원 좌표평면의 좌표계를 설정하여 정중선상의 soft tissue Nasion, Pronasale, Subnasale, Upper lip center, Lower lip center, soft tissue B, soft tissue Pogonion, soft tissue Menton 등 8개의 계측점과 양측성인 Endocanthion, Alare lateralis, Cheilion, soft tissue Gonion, Tragus, Zygomatic point 등 총 20개의 재현 가능한 안면 연조직의 계측점을 지정하였으며 V surgery 프로그램(Cybermed Inc., Seoul, Korea)을 이용하여 이들 계측점의 3차원적인 좌표와 기준 원점으로부터 각 계측점까지의 Net (δ=√ (X^(2)+Y^(2)+z^(2))) 값의 평균과 표준편차를 구하였다. 안면 연조직 분석의 3차원적인 이해를 돕기 위해 주요 계측점 간의 거리 계측을 시행하였고, 그 결과 Na'-Sn과 En(Rt)-En(Lt)를 제외한 대부분의 계측값에서 남녀간의 유의한 차이가 있었으며, 2차원적인 두부 방사선 규격사진이나 안면 사진으로는 정확한 계측이 어려웠던 Na'-Zy, Na'-Ch, Na'-Go' (facial depth) 등의 정상치도 구하였다. 이상의 자료는 부정교합 환자와 악안면 기형 환자의 3차원적인 진단 및 치료 계획에 참고자료로 사용될 수 있을 것이다. Studies for diagnostic analysis using three-dimensional (3D) CT images are recently in progress and needs for 3D craniofacial analysis are increasing in the fields of orthodontlcs. It is especially essential to analyze the facial soft tissue after orthodontic treatment and orthognathic surgery. In this study 3D CT images of adults with normal occlusion were taken to analyze. the facial soft tissue. Norms were obtained from CT images of adults with normal occlusion (12males, 11 females) using a computer program named V works 4.0 program. 3D coordinate planes were established using soft tissue Nasion as the reference point and a total of 20 reproducible landmarks of facial soft tissue were obtained using the multiple reconstructive sectional images (axial, sagittal and coronal images) of the V works 4.0 program: soft tissue Nasion, Pronasale, Subnasale, Upper lip center, Lower lip center, soft tissue B, soft tissue Pogonion, soft tissue Menton, Endocanthion (Rt/Lt), Alare lateralis (Rt/Lt), Cheilion (Rt/Lt), soft tissue Gonion (Rt/Lt), Tragus (Rt/Lt), and Zygomatic point (Rt/Lt). According to the established landmarks and measuring method, the 3D CT images of adults with normal occlusion were measured and the normal positional measurements and their Net (δ=√ (X^(2)+Y^(2)+z^(2))) values were obtained using V surgery program. In the linear measurement between landmarks, there was a significant difference between males and females except Na'-Sn and En(Rt)-En(Lt). The normal ranges of Na'-Zy, Na'-Ch and Na'-Go' (facial depth) were obtained. which was difficult to measure by two-dimensional (2D) cephalometric analysis and facial photographs. These data may be used as references for 3D diagnosis and treatment planning for patients with malocclusion and dentofacial deformity.

개심술(開心術)의 임상적 고찰 : 치험 200예 200 Cases

최형호,서홍주,임영혁,김정중,배대양,이석기,임진수 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.2

Background and Objectives: Two hundred cases of the open heart surgery due to congenital and acquired heart disease were done using the cardiopulmonary bypass in the Department of Thoracic and Cardiovascular surgery, Chosun University Hospital from November, 1980 to June, 2001. Material and Methods: The number of congenital heart disease was 132 cases. 68 cases were acquired heart disease. 'The age of the congenital heart disease was from 22 days to 45 years. In the acquired heart disease, the age was from 14 to 72 years. Result: Congenital heart disease consisted of 113 congenital acyanotic heart disease, 19 congenital cyanotic heart disease. Corrective operation was done for congenital heart disease with 4. 5 % operative mortality. Of 68 cases acquired heart disease, 44 patients were valvular heart disease, 3 cardiac tumors, 9 ischemic heart diseases, 12 aortic dissections and etc. The operative mortality was 13%. Conclusion: The postoperative complications were appeared in 68 cases and the complications were wound infection, occipital alopecia, low cardiac output syndrome, arrhythmia, septicemia etc. The mortality after open heart surgery was 15 cases and the causes of death were low cardiac output syndrome, septicemia, respiratory failure and left ventricle rupture.

비글개에서 분만 후 자궁수복의 연속적 초음파상

손형원, 김홍석, 김형진, 김일화, 이기창, 이청산, 강현구 충북대학교 동물의학연구소 2006 Journal of Biomedical and Translational Research Vol.7 No.2

본문참고

Tripledecker 착물, (CpCo)_2(C_4R_4)과 Alkyne과의 반응

嚴在國,李元植,金碩峯,車震淳,李炯秀,李東鎬,金洪碩,沈相喆 대구효성가톨릭대학교 자연과학연구소 1993 基礎科學硏究論集 Vol.1993 No.1

트리플데카 착물류, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt들은 Jonas시약과 2-hexyne 또는 3-hexyne을 실온에서 동량으로 반응시킬때, 50% 이상의 최대 수율이 얻어졌다. 한 종류의 트리플데카 착물인 bis-(η^5-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt(13)는 실온에서 3-hexyne과 반응시키면, 착물 (η^5-cyclopentadienyl)cobalt-acyclopentadiene-μ-(η^4-2,4-cobaltacyclope-ntadiene)(η^5-cyclopentadienyl)cobalt(15)로 이성화되었다. 다른 한 종류의 트리플데카 착물, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,3-dimethyl-2,4-dipropyl-cyclobutadiene)dicobalt(14)를 2-hexyne 과 반응시켰더니 1,3,5-tri-methyl-2,4,6-tripropyl benzene화합물이 생성되었다. The tripledecker complexes, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt were produced by the reaction of Jonas reagent with 2-hexyne and 3-hexyne in the maxi-mum yield(above 50%) when they were reacted in eq-molar amounts at room temperature. A tripledecker complexes,bis-(η^2-cyclopentadienyl)-μ-(η^4-1,2,3,4-tetraalkylcyclobutadiene)dicobalt(13) was isomerized to (η^5-cyclopentadienyl)cobalt-acyclopentadiene-μ-(η^4-2,4-cobaltacyclope-ntadiene)(η^5-cyclopentadienyl)cobalt(15) on reacting with 3-hexyne at room temperature. Another tripledecker complex, bis-(η^5-cyclopentadienyl)-μ-(η^4-1,3-dimethyl-2,4-dipropyl-cyclobutadiene)dicobalt(14) was decomposed to give 1,3,5-trimethyl-2,4,6-trip-ropylbenzene through an intermediate complex by the reaction of 2-hexyne.