문화유산을 활용한 테마파크형박물관에 관한 연구

박소라(Park, So La),우성호(Woo, Sung Ho) 한국실내디자인학회 2013 한국실내디자인학회논문집 Vol.22 No.6

The number of visitors to historic sites and museums in Korea has been on a rapid decrease and in order to search for creative ways to work on the problem, the study proposed a theme park-typed museum with cultural heritage applied and reviewed spatial strategies for such theme park-typed museums. Applied methods of research of this study are as follows. First, in order to understand definitions and current situations of cultural heritage use and theme park-typed museums, the study went thoroughly over all sorts of literature and reports as well as findings of advance researches on how to make a use of cultural heritage. Based on the results of the investigations, the study determined characteristics of the theme park-typed museums with cultural heritage applied which the study was proposing and the characteristics were categorized by type. Considering those characteristics and types gained in the study, the study looked for cultural heritage-based theme parks and museums in the world which were good enough to be used as research subjects in the study from the aspects of profitability and level of awareness. The study examined those theme parks and museums in the world and in the end, it found out ways to adopt the findings to the situations in Korea and discussed expecting effects as well. As to the characteristics of the theme park-typed museums with cultural heritage applied, the study divided those characteristics into mutual cooperation, location, communicability, authenticity, maintainability, education, durability, narrativity, undailiness, interactivity and leisure. The types were categorized into ride, environment direction, cartoon character and souvenir by attraction pattern. When cultural heritage is used actively, it would improve competitiveness of historic cultural sites and museums in return, making people realize the iterative structure of excavation, conservation, maintenance and use of cultural heritage. That would create many kinds of added values, re-discovering culture of the country. At the same time, it would also create a new value of culture as well. Now, it is important for us to do harder with researches on how to evolve museums and exhibition spaces. Considering that, the study is believed to make a contribution to revival of historic sites and museums in Korea but also establishment of scientific strategies.

Heme oxygenase-1 induced by desoxo-narchinol-A attenuated the severity of acute pancreatitis via blockade of neutrophil infiltration

Bae, Gi-Sang,Kim, Dong-Goo,Jo, Il-Joo,Choi, Sun-Bok,Kim, Myoung-Jin,Shin, Joon Yeon,Kim, Dong-Uk,Song, Ho-Joon,Joo, Myungsoo,Park, Sung-Joo ELSEVIER 2019 INTERNATIONAL IMMUNOPHARMACOLOGY Vol.69 No.-

<P><B>Abstract</B></P> <P>Heme oxygenase-1 (HO-1) has an anti-inflammatory action in acute pancreatitis (AP). However, its mechanism of action and natural compounds/drugs to induce HO-1 in pancreas are not well understood. In this study, we investigated the regulatory mechanisms of HO-1 during AP using desoxo-narchinol-A (DN), the natural compound inducing HO-1 in the pancreas. Female C57/BL6 Mice were intraperitoneally injected with supramaximal concentrations of cerulein (50 μg/kg) hourly for 6 h to induce AP. DMSO or DN was administered intraperitoneally, then mice were sacrificed 6 h after the final cerulein injection. Administration of DN increased pancreatic HO-1 expression through activation of activating protein-1, mediated by mitogen-activated protein kinases. Furthermore, DN treatment reduced the pancreatic weight-to-body weight ratio as well as production of digestive enzymes and pro-inflammatory cytokines. Inhibition of HO-1 by tin protoporphyrin IX abolished the protective effects of DN on pancreatic damage. Additionally, DN treatment inhibited neutrophil infiltration into the pancreas via regulation of chemokine (C-X-C motif) ligand 2 (CXCL2) by HO-1. Our results suggest that DN is an effective inducer of HO-1 in the pancreas, and that HO-1 regulates neutrophil infiltration in AP via CXCL2 inhibition.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Desoxo-narchinol-A (DN) is a natural compound of HO-1 inducer in pancreas. </LI> <LI> Mechanism of DN-induced HO-1 is mediated by MAPK/Activator Protein-1/HO-1 signaling. </LI> <LI> DN-induced HO-1 blocks neutrophil infiltration into pancreas via inhibition of CXCL2. </LI> <LI> DN inhibits cerulein-induced acute pancreatitis (AP) and AP-associated lung injury. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

도시의 모험놀이터‘플레이파크’에 관한 고찰

신순호(Shin Soon Ho),박성현(Park Sung Hyun) 한국도시행정학회 2011 도시 행정 학보 Vol.24 No.1

The purpose of this study is to suggest a preliminary data based upon implications from the analysis of Japan’ s Play Park that how we could introduce Play Park in the urban environment. With this in mind, We have looked at the concept of Play Park, the history of Play Park, and the role of Play Park. After that, We have examined “Hanegi Play Park”, which is known for the most advanced model in Japan, based on the following analytical frameworks. First of all, We identified geographic characteristics (location, area, space, facilities, and tools), and then looked into utilization(number of users, age of users, and contents of play), operating structure(operating system and solidarity), and operating contents and method(finance, safety, program, and insurance). In order to enhance the accuracy of research, We have used the different way of research according to its characteristics such as geographic characteristics with observation and utilization, operating structure, and operating contents and method with interview. After analyses, We have found out that a few thing were shall be considered before it introduced Play Park in urban environment. First, Play Park did not require special components such as condition of site and man-made structures, therefore We suggested that we should consider trying the existing park that hardly uses or becomes obsolete on a trial basis. Second, We suggested that we need to take account of operating solidarity in order to make the best use of Play Park. In other words, it shall be an organic cooperation system that local government limits their role to provide only place and finance, while residents could take charge of Play Park operation and all other matters as a “trust”way. Last but not least, it should be discussed how to raise funds. In case of “Hanegi Play Park”, it consists of two parts with ratio of 3:1; consignment fee from local government and earnings from own business. We, however, need to discuss whether this ratio is reasonable or not. It is more desirable to raise funds through own business as much as possible rather than local government financial support.

PGA2 induces the expression of HO-1 by activating p53 in HCT116 cells

Hyein Lee,Sang-Sun Lee,Ji-Young Park,Yun-Jeong Choe,이선영,Ho-Shik Kim,H.-S. Kim 대한독성 유전단백체 학회 2017 Molecular & cellular toxicology Vol.13 No.2

Prostaglandin (PG) A2 which is a cytotoxic PG, was reported to induce the expression of heme oxygenase (HO)-1 via activation of p38MAPK to keep U2OS cells from cell cycle arrest in G2M phase. The expression of HO-1 is primarily regulated at the level of transcription. But the transcription factors that are responsible for PGA2-induced HO-1 expression were not clarified yet. Here, we report that PGA2-induced transcription of HO-1 is mediated by p53, a tumor suppressive transcription factor. In HCT116 cells, PGA2 treatment led to the phosphorylation of p53 and an increase of p21WAF1 transcription as well as the activation of HO-1 transcription. Knocking p53 down via RNA interference or inhibiting the p53’s transcriptional activity by pifithrin-α treatment led to suppression of the increase in the level of both HO-1 expression and activity of HO-1 promoter. Pretreatment of NU- 7441, a chemical inhibitor of DNA-activated protein kinase (DNA-PK), prevented both the PGA2-induced phosphorylation of p53 and an increase of HO-1 transcription. In addition, N-acetyl-l-cysteine, a scavenger of reactive oxygen species (ROS), also mimicked the effect of NU-7441 on the PGA2-induced activation of p53 and HO-1 transcription. Collectively, these results suggest that PGA2 induces the expression of HO-1 via activation of p53, which is mediated by the ROSDNA- PK pathway.

12M의 고해상도 360° 카메라를 사용한 주차장의 14면 주차 상태 판단 프로그램

이영지(Young-Ji Lee),이희열(Hee-Yeol Lee),고태영(Tae-Young Ko),곽동훈(Dong-Hoon Kwak),김재형(Jae-Hyung Kim),김주호(Joo-Ho Kim),오승진,이태윤(Tae-Yoon Lee),박상민(Sang-Min Park),이승호(Seung-Ho Lee) 대한전자공학회 2019 대한전자공학회 학술대회 Vol.2019 No.6

In this paper, we propose a program to identify 14 parking status in a parking lot using a high resolution 360° camera of 12M. The proposed program consists of three steps: Match with plane image, parking area detection algorithm, and discrimination of parking using learning method. Tests on a model car to evaluate the program to identify 14 parking status in a parking lot using a high-resolution 360° camera of 12M showed 100% accuracy for both parking and double parking. Therefore, the effectiveness of a program to identify 14 parking status in a parking lot using a high-resolution 360° camera of 12M proposed in this paper has been proved.

Synthesis of Sr Doped HoCrO3 Solid Solution Systems and Their Electrical Properties

PARK, SUNG HO,Kwon, Tae Yun 한국공업화학회 2000 Journal of Industrial and Engineering Chemistry Vol.6 No.4

Ho_(1-x)SrxCrO₃ systems, with perovskite structures, were synthesized for x=0, 0.05, 0.1, 0.2 at 1300 ℃ under atmospheric pressure. The results of X-ray analysis reveals that these prepared systems forms orthorhombic structures. Also, the HoCrO₃ systems which were doped with Sr cations on the site of Ho cations, exhibited a linear increase in their cell volume. It was found that the lattice parameter and reduced volume increased as the doping level of Sr^(2+) increased. From the measurements of D.C conductivity, the activation energy obtained from the conductivity dependence on temperature was 0.18 eV. The conduction mechanism would appear to be the hopping model of electron conduction.

Protective Effect of Baicalin Against Carbon Tetrachloride–Induced Acute Hepatic Injury in Mice

Park, Sang-Won,Lee, Chan-Ho,Kim, Yeong Shik,Kang, Sam Sik,Jeon, Su Jin,Son, Kun Ho,Lee, Sun-Mee The Japanese Pharmacological Society 2008 JOURNAL OF PHARMACOLOGICAL SCIENCES Vol.106 No.1

<P>This study examined the effects of baicalin, a bioactive flavonoid isolated from <I>Scutellariae Radix</I>, on carbon tetrachloride (CCl<SUB>4</SUB>)-induced liver injury. Mice were treated intraperitoneally with 0.5 ml/kg CCl<SUB>4</SUB> and different groups of animals received 25, 50, 100, and 200 mg/kg baicalin. At 24 h after the CCl<SUB>4</SUB> treatment, the level of serum aminotransferases and lipid peroxidation was significantly elevated, whereas the hepatic glutathione content was decreased. These changes were attenuated by baicalin. The histological studies showed that baicalin inhibited the portal inflammation, centrizonal necrosis, and Kupffer cell hyperplasia, which are the three most common characteristics of CCl<SUB>4</SUB>-induced liver damage. The serum level and mRNA expression of tumor necrosis factor-α were markedly increased by the CCl<SUB>4</SUB> treatment but suppressed by baicalin. The mRNA and protein expression levels of inducible nitric oxide synthase and heme oxygenase-1 increased significantly at 24 h after the CCl<SUB>4</SUB> treatment. Baicalin attenuated the increase in the protein and gene expression of inducible nitric oxide synthase but augmented the increase in those of heme oxygenase-1. These findings suggest that baicalin protects hepatocytes from the oxidative damage caused by CCl<SUB>4</SUB>, and this protection is likely due to the induction of HO-1 expression and the inhibition of the proinflammatory mediators.</P>

계룡산국립공원의 나비류 군집에 관한 연구

전성재 ( Sung Jae Jeon ),조영호 ( Young Ho Cho ),한용구 ( Yong Gu Han ),김영진 ( Young Jin Kim ),최민주 ( Min Joo Choi ),박영준 ( Young Jun Park ),남상호 ( Sang Ho Nam ) 한국환경생태학회 2012 한국환경생태학회지 Vol.26 No.3

고도의 변화는 종 다양성 및 풍부도 그리고 생물 종 구성에 있어 매우 중요한 역할을 하는 요인으로 최근에는 나비를 비롯하여 곤충의 고도에 따른 분포 형태에 관하여 많은 관심이 집중되고 있다. 본 논문에서는 계룡산국립공원의 고도에 따른 나비분포를 조사하여, 종 보전 및 효율적인 관리방안을 제시하고자 하였다. 본 연구에서는 고도가 증가함에 따라 종과 개체수가 감소하는 경향이 나타났으며, 이는 수관울폐로 인한 그늘의 증가가 원인일 것으로 사료된다. 고도의 영향 이외에도 종의 분포에 영향을 주는 요인을 분석한 결과, 경사도 및 식생군락 그리고 수계거리가 종의 분포 변화와 상관관계가 있는 것으로 조사되었다. 이러한 종들은 먹이식물과 밀접한 관련이 있으므로 추후에 숲 내부의 변화를 감지하는데 적합한 생물지표종을 선정한다면 시간과 비용을 감소시킬 수 있을 뿐만 아니라 효율적인 생물다양성 평가를 내릴 수 있을 것으로 판단된다. 또한 추후에 기후 및 미기후, 그리고 먹이식물과 같은 환경요인들의 자료를 축적하고 정량화 할 경우 나비 분포를 예측할 수 있어 종 보전에 있어 더 효율적이라고 사료된다. Altitude is a factor that plays an important role in the diversity, richness and composition of species. Recently, much attention has been paid to the distribution of butterflies and insects according to altitude. The purpose of this article is to propose a method to preserve and manage species efficiently by reviewing the distribution of butterflies according to different altitudes in Mt. Gyeryong National Park. This study found that the number of species and individuals decreased as the altitude increased, possibly due to the increased amount of shade caused by the crown density. When analyzing the factors influencing the distribution of species other than altitude, it was found that the slope, vegetative colonies and hydrosphere distance were correlated with the change in species distribution. As these species are closely related to food plants, it may save time and reduce the cost as well as allow an efficient evaluation of the bio-diversity if these species are selected as biological indicator species suitable for detecting the changes in the forest. It is judged to be a more efficient means of species preservation to accumulate and quantify the materials regarding environmental elements such as the climate, microclimate and food plants, as this would allow the butterfly distribution to be estimated.

경부고속철도건설사업 성과평가

송성태(Sung Tae Song),최문규(Moon Kyu Choi),박상구(Sang Gu Park),장호환(Ho Hwan Jang),차효정(Hyo Jung Cha) 한국철도학회 2012 한국철도학회 학술발표대회논문집 Vol.2012 No.5

1992년 첫 삽을 뜨면서 시작한 경부고속철도건설사업이 2004년 4월, 1단계 개통을 한데 이어 지난 2010년 11월 완전 개통하였다. 경부고속철도 개통으로 경부축 지역의 2시간대 서비스 제공을 통한 국토의 균형발전 촉진 및 여가·관광사업 활성화, 기술발전, 환경비용 및 에너지 절감 등 긍정적인 효과를 이룬 반면, 잦은 기본계획 변경으로 인한 사업비 및 사업기간의 증가, 현실과 맞지 않은 설치기준으로 인한 과잉설계 문제 등 부정적 효과도 초래했다. 본 연구를 통해 사업추진 단계별 주요 이슈에 대해 객관적인 시각으로 문제점을 분석하고 시사점을 도출함으로써, 현재 추진하고 있는 호남고속철도와 수도권고속철도 사업에서는 시행착오를 줄이고 사업을 효율적으로 추진하는데 활용하고자 한다. Launched in 1992, the Gyeung-Bu High Speed Railway (HSR) was fully opened in November 2010 following the partial opening of the first phase in April 2004. Since the opening it has made tremendous achievements, including but not limited to, technical innovation, balanced regional development, growth of leisure and tourism industries, and savings of environmental costs and energy. On the other hand, it has brought negative effects such as increase in project time and cost by frequent changes of the basic plan and over-design based on unrealistic criteria. In this study we will analyze major issues that occurred at each stage of the Gyeong-Bu HSR project and draw implications. Thus, this study will enhance to efficiently implement the Ho-Nam and Seoul Metropolitan HSR project through minimizing possible trials and errors.

SNS의 여론형성과정과 참여행태에 관한 고찰

박상호(Sang-Ho Park) 한국언론정보학회 2012 한국언론정보학보 Vol.58 No.2

본 연구는 SNS의 여론형성과정과 참여행태에 관한 연구이다. 대표적인 SNS 서비스인 트위터가 무상급식 주민투표와 10.26재보선 기간의 여론형성에 미치는 영향을 고찰하였다. 특히, 여론형성의 유력자인 파워 트위터리안이 영향력을 분석하였다. 첫 번째 연구문제인 트위터의 여론형성에 관한 분석결과, 무상급식 주민투표의 경우 오전시장이 대권 불출마선언 이후에 무상급식 주민투표에 대한 국민들의 관심이 폭발적으로 늘어났으며, 오전시장을 지지하는 트윗보다는 반대하는 트윗의 영향력이 컸다. 10.26재보선의 경우 트위터공간에서 나 후보자보다는 박 후보자가 촘촘한 소통망을 형성하면서 자신에게 호의적인 여론을 형성하였다. 두 번째 연구문제인 파워 트위터리안과 일반 트위터리안의 참여행태에 관한 분석결과, 무상급식 주민투표의 경우 유명스타들이 파워 트위터리안으로써 사회이슈에 대한 참여를 선도하는 역할자로 자리매김하게 되는 계기를 마련했다. 파워 트위터리안은 일반 트위터리안의 공감을 끌어내는 데 성공하였다고 평가된다. 10.26재보선의 경우 박 후보를 지지하는 파워 트위터리안이 나 후보를 지지하는 파워 트위터리안보다 많았을 뿐만 아니라 박 후보와 소통을 하고 있는 일반 트위터리안도 훨씬 많았다. 특히, 박 후보를 지지한 파워 트위터리안이 보유한 커뮤니티의 규모는 나 후보를 지지한 파워 트위터리안의 5배가 넘었다. 파워 트위터리안과 일반 트위터리안의 관계는 단순한 지지가 아닌 서로 간의 공감을 전제로 관계가 형성되고 있다. 전통적인 언론을 통한 여론형성과정에서 국민들은 단순히 여론에 휩쓸리는 대상에 불과하였지만, SNS가 확대되면서 이슈의 생산과 유통에 참여하고 이슈를 선도하는 역할을 하는 것으로 평가된다. This study is critical research on the forming public opinion of SNS and participation behavior. Twitter is a typical SNS service, free school food and 10.26 re-and by-elections during the formation of public opinion on the impact have been investigated. Formation of public opinion about Twitter’s analysis of the first research question, The case of free meals to support the Mayor Oh, rather than against Twitter were influential. 10.26 re-and by-elections Twitter in space, the Park‘ candidate than Na’ candidate has formed a favorable opinion. Power twitterian and twitterian on the behavior of the second study involved analysis of the problem, For free meals, power twitterian were responsible for leading the public opinion. For 10.26 re-and by-elections, Power twitterian were more Park‘ candidates than Na’ candidates. In addition, Park‘ candidates of twitterians were communicating more. Through traditional media in the process of forming public opinion was swayed by public opinion to the target people simply but SNS age people involved in the production and distribution of the issue and the issue has a leading role.