돼지에서 정맥, 근육 그리고 경구 투여시의 enrofloxacin의 약물동태학

윤효인,김무열,박승춘,조준형,박병권,이내경,노상석,장범수,신광순,조명행 충남대학교 수의과대학 동물의과학연구소 1996 動物醫科學硏究誌 Vol.4 No.-

In order to characterize pharmacokinetic profiles according to route of a new enrofloxacin salt form (Enrotil®), it was given to 4 healthy pigs via oral (p.o.), intramuscular (i.m.) or intravenous (i.v.) administrations at a dose rate of 5 ㎎/㎏ body weight. Enrofloxacin (ENFX) in serum was detected by bioassay using E. coli BE1186 as a test organism. The biological elimination half-lives (t_1/2(β)) of ENFX were 6.76±0.99 h (i.v.), 7.16±2.30 h (i.m.) and 11.45±3.90 h (p.o.), Volume of distribution (Vd) of enrofloxacin was 2.20±0.31 L/㎏ (i.v.), 2.52±0.60 L/㎏ (i.m.) and 1.88±0.33 L/㎏ (i.m.). Mean residence time (MRT) was 8.77±1.26 h after i.v. injection and the maximal concentration time (Tmax) following p.o. and i.m. administration was 0.76±0.09 h and 0.60±0.12 h, indicating a rapid absorption from these routes. Bioavailibility (F) was calculated as 64.1% for p.o. administration and 59.71% for i.m. injections. In summary, the newly formulated enrofloxacin salt form has shown a high water solubility, rapid absorption and large tissue distribution, suggesting a potential antibacterials for oral application on a large scale in veterinary sectors.

葡萄 Muscat Bailey A의 無核果 生産을 爲한 Streptomycin 利用 試驗(Ⅱ)

蔡潤錫,朴相眩,安相烈 진주산업대학교 농업기술연구소 1993 農業技術硏究所報 Vol.6 No.-

GA_3 100ppm單用과 GA_3 100ppm+Streptomycim 200ppm 混用을 葡萄 Muscat Bailey A 品種의 滿開期 10日前에 新稍長 30, 40, 50cm의 着果房에 處理한 結果는 다음과 같다. 1. 熟期는 兩處理區 모두 無處理보다 20日 前後 早熟되었으며 混用區는 GA_3 單用區 보다 2∼3日 빠른 傾向을 보였고, 新稍의 길이에 따른 差異는 비슷하였다. 2. 有核粒數는 無處理 平均 5∼6個에 비해 混用 및 GA_3 單用 모두 無核의 傾向을 보였는데 新稍長 50cm의 GA_3 單用區에서 1∼2個의 有核粒을 나타내었다. 3. 果房長의 兩主區의 新稍길이 30cm와 40cm 處理區는 비슷하였으며 상품성이 없었고, 50cm, 處理區에서는 높은 有意性을 보였다. 4. 果房重은 GA_3 單用區가 混用區보다 80∼90g정도 무거웠으며, 新稍길이 間에는 50cm處理區에서 가장 무거웠고 과방당 과립수와 평균과립중도 50cm 처리구에서 고도의 유의성을 나타내었다. 5. 糖度는 混用區가 單用區보다 높고, 新稍의 길이間에는 길수록 다소 높은 傾向을 보였다. GA_3 100ppm solution and GA_3 100ppm+streptomycin 200ppm solution are applied on the cluster of 30, 40, 50cm shoot length of Muscat Bailey A variety at 10 days before full bloom day. The results are as follows : 1. The maturing season was 20 days or so ealier in both exprimental plots than in the control plot. The GA_3+streptomycin solution applied grapes atured 2∼3 days ealier than the GA_3 solution applied grapes. Thd shoot length of application revealed little difference. 2. The GA_3+streptomycin plot and GA_3 plot produced no seed holding berry, but the control plot produced 5∼6 seed holding berries. GA_3 of 50cm shoot length plot produced 1∼2 seed holding berries. 3. The cluster length of 30, 40cm shoot length plot among both main plots were similar and the value of merchandise were not found. The 50cm shoot length plot among both main plots showed high significant difference. 4. The cluster weight of GA_3 plot was significantly 80∼90g heaviet than that of GA_3+streptomycin plot. The cluster weight of 50cm shoot length plot was the heaviest. The berry number per cluster and average berry weight of 50cm shoot length plot showed high significant differencd. 5. The sugar content of berry was significant larger in the GA_3+streptomycin plot than in the GA_3 plot. The longer shoot length was, the larger the sugar content of berry was.

정신과 환자에서 간이정신진단검사의 요인구조

오상우,김윤희,고효선,이상열,노승호 圓光大學校 醫科學硏究所 2008 圓光醫科學 Vol.23 No.2

배경: 본 연구는 SCL-90-R에서 9개 증상차원의 요인구조가 어떻게 나타나는지를 알아보는 데 목적이 있다. 방법: SAS 프로그램을 이용하여 정신과적 장애로 진단받은 환자 188명이 수행한 SCL-90-R 자료의 요인구조를 분석하였다. 결과: 요인분석 결과 SCL-90-R의 9개 증상차원은 단일요인으로 나타났다. 결론: SCL-90-R의 요인분석 결과 단일 요인 모형이 탐색되었다. 추후 연구에서는 SCL-90-R의 9개 척도에 대한 확인적 요인분석이 필요할 것으로 생각된다. Background: To find of this study was to find exploratory factor analysis of the nine scales of the Symptom Checklist-90-Revision(SCL-90-R). Methods: This study was investigated the factor structures of nine scales of the SCL-90-R in 188 patients with psychiatric disorders using SAS 8.02 software. Results: The factor structure showed that the factor structures of nine scales of the SCL-90-R had one factor. Conclusion: The factor structures showed that the factor structures of the SCL-90-R had one factor. Further research is nedeed about confirmatory factor analysis of the nine scales of the SCL-90-R.

재래종 참외 종자 및 생육초기 주요형질의 유전력과 상관관계 분석

이상우,박상현,강호종,안상열,채윤석,김주현 진주산업대학교 농업기술연구소 2000 農業技術硏究所報 Vol.13 No.-

This experiment was conducted to obtain some basic imformation for korean native oriental melon breeding. Genetic variability, heritability, and correlation on 13 characters were analyzed. The results are summarized as follows; 1. Among 13 characters, plant height and length of lateral shoot showed high level of GCV(110-362%) and ECV(89-101%). The rest characters showed low level of GCV(7-21%) and ECV(0.16-9%). 2. Heritabilities of 13 characters investigated were high as over 50%. Especially those of hypocotyl length, 100-seed weigth and seed width were very high (> 95%). 3. High level correlation values were observed among seed characters and seedling characters. 4. Plant characters of early growth stage, except leaf stalk length, were not related with characters of seed or seedling 5. In early plant growth stage, plant height and length of lateral shoot were correlated positively with number of node, number of lateral shoot, leaf length and leaf width.

Gibberellin Paste 處理가 배 행수의 品質에 미치는 影響

안상열,박상현,채윤석 진주산업대학교 1993 論文集 Vol.32 No.-

The size, weight, sugar content and firmness of the pear, "Kosui", treated gibberellin paste on the fruit stalk on 20, 30, 40days after full blossom were determined. Treating dates had significant effect on the diameter(either horizontal or longitudinal) of fruits. There was significant increase in fruit weights treated gibberellin paste on 20 and 30 days after full blossom. Sugar content and firmness of the fruit resulted similarity in each plot.

우심방과 우심실의 거대 심장 혈관종 1예

김제열,조상호,김건일,허경림,김현숙,조구영,최영진,이원용,임종윤 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Cardiac tumors, especially the primary tumors involving any part of the heart are extremely rare and its relative incidence has been reported to be approximately 0.02%. We report a patient with huge cardiac hemangioma who complained of shortness of breath, general weakness, and dizziness, Imaging study by echocardiography and computed tomography of thorax revealed a huge lobulating mass like a bunch of grapes in the right chamber of heart. The surgical exploration of thorax was performed and a histological diagnosis of spindle cell hemangioma was obtained by microscopy. The patient was treated by surgical resection of the tumor and doing well after surgery. Our experience indicated that prompt diagnosis and treatment of cardiac hemangioma is imperative for patients' prognosis.

도토리 과수화 가능수종의 특성에 관한 연구

안상열,박상현,채윤석 진주산업대학교 농업기술연구소 1998 農業技術硏究所報 Vol.11 No.-

한국 자생 도토리를 과수화 하기 위한 각 선발수들의 특성에 관한 조사결과는 다음과 같다. 상수리 선발수의 평균엽장이 138.9mm, 엽폭은 42.4mm, 평균과중은 3.9g이였고 과형은 원형이였다. 졸참나무 선발수의 평균 엽장은 126.omm, 엽폭은 53,4mm, 평균과중은 2.4g이였고 과형은 장타원형이였다. 굴참나무 선발수의 평균엽장은 135.6mm, 엽폭은 49.0mm였으며, 평균과중은 2.9g이였고, 과형은 약간 타원형이였다. 갈참나무 선발수의 평균엽장은 153.6mm, 엽폭은 83.0mm였으며, 평균과중은 2.4g의 장타원형이였다. 특히 도토리의 결실성이 좋은 것은 M-2, H-25, K-1, K-2, HC-, Ch-2, Ch-3, S-3, S-7, SV-0, SV-2등으로 관찰되었다. This study attempted to make some basic investigations for the cultivation of Korean native acorn tree as a new fruit tree crop. The characteristics of the selected trees were analyzed as follows. In the case of Quercus acutissima CARRUTHERS, the average of leaf length of the selection trees was 138.8mm : the average of leaf width was 42.4mm : the average of fruit weight was 3.9g ; the shape of fruit was round. In the case of quercus serrata THUNBERG, the average of leaf length was 126.9mm ; the average of leaf width was 53.4mm ; the average of fruit weight was 2.4g ; the fruit shape was a long oval. In the case of Quercus variabils BL., the average of leaf length was 135.2mm ; the average of leaf width was 49.0mm the average of fruit weight was 2.9g ; the fruit shape was a little longish. In the case of Quercus aliena BLUME, the average of leaf length was 153.6mm ; the average of leaf width was 83.0 ; the average of friut weight was 2.4g ; the shape of the fruit was longish. Specially good maturity was observed in the acorns of M-2, H-5, K-1, K-2, HC-1, Ch-2, Ch-3, S-3, S-7, SV-0 and SV-2 classifications.

시판용 상토 종류가 배추 유묘기 묘소질에 미치는 영향

이상우,강호종,안상열,채윤석,윤재길,최경옥 진주산업대학교 농업기술연구소 2007 農業技術硏究所報 Vol.20 No.-

시중에 판매되고 있는 상토는 제조 회사에 따라 재료의 구성 및 혼합 비율이 다르다. 시판용상토를 제조사별로 구입하여 상토 제조사에 따라 배추 육묘기 묘소질에 미치는 영향에 대해 조사하였다. 상토 제조사 별로 배추의 지상부 및 지하부의 생육에 많은 차이가 있었다. 그리고 엽록소 함량 및 단백질 함량에도 차이가 많았으며, 엽록소 및 단백질 함량이 높았던 상토에서 배추의 생육이 좋았다. 상토 제조사별로 상토의 재료 및 혼합비율에 따라 배추의 유묘기 생육에 많은 영향을 미치는 것으로 나타났다. The substrate is very important to grow seedling because of directly effect on seedling quality of Chinese cabbage. The substrates manufactured by the companies consist of different materials and mixing ratios. This study was conducted to observe the seedling quality of Chinese cabbage by using of the kinds of substrate. The number of leaf, leaf area, fresh weight, dry weight, root length, root weight and T/R ratio of the seedling were shown in different from each substrate manufactured by the companies. And chlorophyll and protein content of the seedling were also shown in different from substrates supplied from the companies, respectively. Substrate which was high in that was also higher in seedling quality. The material and mixing ratios of substrate effected on the growth of cabbage

감자의 가공품질에 영향을 미치는 토양 및 기상조건

정진철,윤영호,장동칠,박천수,김숭열 한국환경농학회 2003 한국환경농학회지 Vol.22 No.4

감자의 가공품질에 영향을 미치는 토양 및 기상조건을 구명하기 위하여 국내 주요 감자재배 지역 7곳에 1994년부터 1995년까지 2년에 걸쳐 각 지역별 2~3개 농가에서 감자를 재배하였으며, 각 재배포장의 토양시료 채취 및 괴경을 수확하였다. 지역별 감자 괴경의 가공품질 차이의 원인을 구명키 위하여 토양분석과 수확일 기준으로 수확전 70~10일 사이의 기상조건을 10일 간격으로 조사하였으며, 수확된 괴경의 가공품질과 이들 요인과의 상관계수를 계산하였다. 시험결과 감자의 가공품질은 토양의 화학적 특성 중에서 토양내 유기물함량과 높은 상관계수를 보였다. 또한 기상조건과 관련하여 수확전 30~10일 사이의 최저온도가 낮으며, 일조시간이 많을수록 감자의 가공품질이 향상되었다. 또한 이들 상관관계가 높은 요인들을 대상으로 가공품질 요인에 대한 다중회귀식을 구한 결과 괴경건물율과 칩색도는 비교적 높은 결정계수를 보여주었다. 따라서 우리나라에서 고품질의 가공원료 생산을 위한 적지 선정에 있어 토양중의 유기물 함량과 그 지역의 최저온도 및 일조시간 둥이 고려되어야 할 것으로 생각된다. In order to examine the difference in processing quality of potato tubers among localities, chemical properties of soils were analyzed and climatic conditions were investigated. potatoes (Solanum tuberosum L) were grow at seven localities of Korea during two years from 1994 to 1995. Soil samples and tubers were obtained from 2 to 3 commercial farms per locality with 10 days interval from 70 days before harvesting. As the result of that, higher correlation in processing quality was found with organic material content among soil conditions. On the climatic conditions, minimum temperature and sunshine hours during the period from 30 to 11 days before harvesting exhibited highly significant negative correlations with all quality parameters except reducing sugar content. Additionally, regression equations based on the observed level of these factors showed the relatively high coefficients of determination for dry matter content and chip color. To produce higher quality potatoes for processing, therefore, climatic conditions such as minimum temperature and sunshine hour and soil condition such as organic matter content have to be considered before the selection of areas or fields.

유아의 애착표상과 또래관계 : 애착의 사례분석을 토대로 based on attachment case analysis

이기영,고윤희,최성열 한국아동교육학회 2004 아동교육 Vol.13 No.2

본 연구에서는 부모와의 애착이 유아에게 하나의 '관계 도식(relational schema)' 이 되어 이를 바탕으로 외부세계에 대한 표상을 한다는 Bowlby의 관점을 취하여, 구체적인 애착 사례를 질적 분석하여 애착이 이후 또래관계 형성에 미칠 수 있는 영향과 그에 따른 교육적 시사점을 살펴보았다. 유아는 부모와의 애착을 형성하는 과정에서 겪게 되는 지속적인 경험은 통해 자신에 대한 중요한 정보를 제공받는 동시에, 또래관계에서 타인의 행동을 지각하고 해석하고 예측하는 표상을 형성하게 된다. 부모와의 관계에서 부정적인 내적실행모덜(internal working model of attachment) 형성된 유아는 또래관계에서 타인에 대한 부정적인 해석과 예측을 하게 되고, 부적응적인 행동을 하면서 또래관계에 부정적 영향을 줄 수 있다. 따라서 유아에게 의미 있는 부모와 교사는 먼저 유아와 안정적인 애착관계를 형성할수 있어야 하며, 이미 부정적인 모델이 형성된 유아라 하더라도 또래집단에서 경험하는 지속적인 긍정적 경험을 통해 타인과의 관계에서 비롯되는 사건과 정보를 왜곡시키지 않도록 도와야 할 것이다. The study adopted Bowlby's point of view on such that preschool child's attachment with the parents as one relational schema becomes a foundation for the representation of the outside world. The study looked at educational suggestion on the effects on the formation of peer relationship after attachment by qualitatively analysing the details of case methods. The child obtains principal information of oneself during the continuous experience when developing attachment with the parents. The child also develops the representation to percept, interpretate and forecast based on others behaviour in peer relation. For those child who has formed negative internal working model attachment during their relationship with the parents may interpretate and forecast negatively towards others within the peer and act with maladjustment, hence having negative influence in the peer relation. Therefore a meaningful parents and childhood teachers are to create a stable attachment relationship with the child. Continuous positive experiences within the peer for those whom has developed a negative model of relationship and attachment will aid in avoidance of misrepresentation of case and information originating by outsiders.