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이상우,박태열,김주혁 東亞大學校附設스포츠科學硏究所 1996 스포츠科學硏究論文集 Vol.14 No.-
The purpose of this study was to evaluate of the cardiorespiatory function and energy expenditure in men-rowing. The subjects were two groups; men rowing group in which career had for 5.4 ±1.13 year, Control group were college students. They did exercise with start speed of 120m/min without treadmill slope, the speed was incremental 20m/min per two minute and they were finally led to exhaustion. The results were as follows; 1. The cardiorespiratory was non-significant difference in rest, during maximum exercise ventilation was 162.6 ±11.69ℓ/min in rowing group, 142.3 ±21.34ℓ/min in control group. ?? o₂max/kg was 61.5 ±4.91㎖/kg/min in control group. The ????, RR ?? o₂, ??o₂/kg were significant difference in during maximum exercise. 2. The energy expenditure was non-significant in rest. The EQO₂was significant difference in rest. The MET in during maximum exercise was 21.2 ±2.67 in rowing group, 18.7 ±4.56 in control group, the cal/day was 5,864.5 ±341.47Kcal in rowing group, 4,662.6 ±563.67Kcal in control group.
이상원,이혁우 부산대학교 사범대학 1990 교사교육연구 Vol.21 No.-
The Chirisan gneiss complex is composed of various paragneisses and small amounts of orthogneisses metamorphosed in Precambrian, which are intruded by gabbroic rock, porphyritic granite and Namwon granite. The gneiss complex was undergone multimetamorhism that early high-grade progressive metamorphism reached to upper amphibolite facies, later amphibolite and epidote-amphinbolite facies(partially to greenschist facies) were overlapped by retrogressive metamorphism. Major mineral assemblage of those gneisses are biotite-garnet,biotitie-garnet-sillimanite,biotite-garnet-cordierite,biotite-garnet-cordierite-sillimanite. Coexisting minerals of 14 samples were analysed by EPMA. Metamorphic conditions were estimated using various experimental, theoretical geothermometers and geobarometers. They show wide ranges of temperature and pressure as 600∼750℃, 720∼820℃, 420∼550℃ of biotite-garnet, cordierite-garnet, alkali feldspar-plagioclase geothermometer and 4.6~6.2Kb, 4.5~7Kb of cordierite-garnet, plagioclase-garnet geobarometer, respectively. But peak metamorphic condition is about 700℃ with 4.67Kb(X=0.40) inferred by plotting of cordierite composition to the P-T diagram under consideration of H₂0 content. The metamorphic path, according to the inferred P-T conditions with the reaction of coexisting minerals and analyses of various geothermo-barometers, is considered that progressive peak metamorphism reached to upper amphibolite facies with partial melting under 700∼750℃, 4.67Kb of temperature and pressure, and later epidote-amphibolite facies was overlapped by the retrogressive metamorphism.
工業敎育大學의 實驗實習施設 共同活用 및 運營에 關한 硏究
尹錫天,牟相榮,權五憲,千炳善,周赫鍾,李永臣,金健中,羅聲雄,洪錫雨,吳德成,盧泰天 충남대학교 공업교육연구소 1983 論文集 Vol.6 No.2(A)
The College of Engineering was specialized to have a sole function for supplying technical high school teachers in 1977 and referred to as the College of Industrial Education according to the Government's policy. The economic impact mainly due to the oil-crises caused a severe problem to this college, namely discrepancy of supply to demand scale. Accordingly the number of student enrollment was to be fluctuated from 479 in 1979 through 800 in 1979 and 900 in 1980 to 430 in 1981. And the engineering departments have been attached to this Engineering Education College since 1981. These circumstanses met singnificant inefficiency in facility operation. This program aims at providing an overall relocation of the college facilities and preparing the practical system to make the joint-operation possible taking into account circulation, academic stream, budget, maintenance, etc. However this study could not get optimal spacing but some trade-off, considering the current situation.
Woo Heon Song,Jong Hyeok Park,Dong Woo Yeom,Byeong Kil Ahn,Kyung Min Lee,Sang Gon Lee,Hye Seung Woo,최영욱 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.1
A supersaturating self-emulsifying drug deliverysystem (S-SEDDS) was prepared and evaluated for enhanceddissolution of celecoxib (CXB), a poorly water-soluble drug. The selected CXB-dissolved SEDDS formulation consisting10 % Capryol 90 (oil), 45 % Tween 20 (surfactant), and45 % Tetraglycol (cosurfactant) had the characteristics ofsmall droplet size and great solubility as 208 nm and556.7 mg/mL in average, respectively. CXB dissolution fromSEDDS in simulated gastric fluid was increased to about20 % for the initial period of 5 min, but decreased to a halflevel as time elapsed. Thus, precipitation inhibitors werescreened to stabilize the supersaturation. The stabilizingeffect of Soluplus, an amphiphilic copolymer, was concentration-dependent, revealing the greatest dissolution ofapproximately 90 % level with delayed drug crystallizationby the addition of the copolymer. CXB dissolution fromS-SEDDS was pH-independent. We concluded that S-SEDDSformulation would be very useful in the future fordeveloping oral delivery product of poorly water-solubledrugs.
Poster Session 1 : Role of carboxy-terminus of p23 in the regulation of its physiological functions
( Sang Hyeok Woo ),( Sung Kwan An ),( Hyeon Ok Jin ),( Hyung Chahn Lee ),( Sung Keum Seo ),( Doo Hyun Yoo ),( Chang Hun Rhee ),( Seok Il Hong ),( In Chul Park ) 한국생화학분자생물학회 (구 한국생화학회) 2005 생화학분자생물학회 춘계학술발표논문집 Vol.2005 No.-
Woo, Sang-Hyeok,Oh, Su-Young,Han, Song-Iy,Choi, Yung-Hyun,Kang, Kwang-Il,Yoo, Mi-Ae,Kim, Han-Do,Kang, Ho-Sung The Korean Society for Integrative Biology 2000 Korean journal of biological sciences Vol.4 No.2
The expression of $p21^{WAF1/ClP1/SDl1}$, one of the cyclin-dependent kinase inhibitors, is regulated by a variety of transcription factors including p53 and STAT. Heat shock induces the expression of p21 in a temperature- and time-dependent manner. Although the p21 induction by heat shock has been reported to be controlled by p53, a p53-independent mechanism Is also involved. To understand the p53-independent regulation of heat shock-induced p21 expression, we searched the promoter region of p21 gene and found one or two heat shock element (HSE)-like sequences in human, rat, and mouse. Electromobility shift assay (EMSA) showed that heat shock factor (HSF) could bind to these HSE-like sequences In response to heat shock, even though to a lesser extent than to HSE. In addition, p21 promoter deletion analysis revealed that heat shock activated a p21 deletion promoter construct containing the HSE-like sequences but lacking p53-binding sites, but not a promoter construct containing neither HSE-like sequences nor the p53-responsive element. Furthermore, the p21 induction by heat shook was significantly inhibited in confluent cells in which heat shock-induced HSF activation was reduced. These results suggest that the transcriptional regulation of p21 by heat shock may be mediated through activation and binding to HSE-like sequences of HSF.
( Sang Myung Woo ),( Sang Hyub Lee ),( Ji Won Yoo ),( Ki Young Yang ),( Jung Gyun Seo ),( Joo Kyung Park ),( Jin Hyeok Hwang ),( Woo Jin Lee ),( Ji Kon Ryu ),( Yong Tae Kim ),( Yong Bum Yoon ) The Editorial Office of Gut and Liver 2013 Gut and Liver Vol.7 No.5
Background/Aims: No standard chemotherapy has been established for advanced gallbladder cancer. The authors studied the activity and tolerability of a gemcitabine and ox-aliplatin (GEMOX) combination in unresectable gallbladder cancer (GBC). Methods: Adult patients with pathologically confirmed unresectable GBC were prospectively recruited at three centers. No patient had received prior chemotherapy or radiotherapy. Patients received cycles of gemcitabine at 1,000 mg/m2 on day 1, followed by oxaliplatin at 100 mg/m2 on day 2, every 2 weeks. The primary study endpoint was time to progression. Results: Forty patients with unresect-able GBC were enrolled. The median age was 60 years (range, 38 to 79 years). All patients showed good performance status. Of the 33 analyzable patients, 12 achieved partial re-sponse (36%), 17 stable disease (52%), and four progressive disease (12%). No patient achieved a complete response. The tumor control rate was 88%. At a median follow-up of 6.8 months, the median time to progression was 5.3 months (95% confidence interval [CI], 3.7 to 6.9), and median overall survival was 6.8 months (95% CI, 6.1 to 7.5). Nine of the 40 patients (23%) experienced at least a grade-3 adverse event, but no patient experienced a grade-4 adverse event. Conclu-sions: GEMOX combination therapy is a feasible option and is well tolerated in unresectable GBC. (Gut Liver 2013;7:594-598)