[cis-Cr(III)(5,5,7,12,12,14-hexamethy1-1,4,8,11-tetraazacyclotetradecane)(L_(a))_(n)]CLO_(4)(n = 1 or 2)합성과 성질

변종철,한성빈,정덕상,임희정,한충훈 濟州大學校 師範大學 科學敎育硏究所 1995 科學敎育 Vol.12 No.1

rac-5.5.7.12.12.14-hexamethy1-1,4,8,11-tetraazacyclotetradecane hydrate : Lm·H_(2)O was prepared and separated from the corresponding meso-isomer dihydrate according to the Curtis method. The racisomer was confirmed by spectroscopic data of NMR and IR spectroscopy. To synthesize the [CrL_m(OH)₂] complex. the racemic compound purified from meso and racemic mixture was reacted with Cr(II1) salt. The complx ion species {[SrL_m(OH)_(2)]^(+): λ_(max) = 613.0(ε_(max) = 116 M^(-1)cm^(-1)), {[CrLm(OH)(H_(2)O)]^(2+) : λ_(max) = 575.0nm(ε_(max) = 133M^(-1)cm^(-1)). [CrLm(H_(2)O)_(2)]^(3+) : λ_(max) = 532.0nm (ε_(max) = 172M^(-1)cm^(-1))} obtained from pH change of [CrLm(OH)_(2)(OH)_(3)]^(+) solution were confirmed from an electron absorption spectra. The result of the distribution diagram of chemical species proves that main products in the range of solution pH ≤ 3.5 . 3.5 <pH <7, and pH ≥ 7. are [CrLm(H_(2)O)_(2)]^(3+). [CrL_(m)(OH) (H_(2)O)^(2+). and [CrL_m(OH)_(2), respectively. At P~ 2.0, we synthesized several Cr(III)-macrocyclic complexes containing various axial ligands (L_(a) : I, Br^(-), CI^(-), S_(2)O_(3)^(2-), F^(-), malonate, NCS^-, oxalate) instead of H_(2)O. [CrL_m(OH_(2))]^(3+) + L_(a) →[CrL_(m)(L_(a))_(n)]^(+)(n = 1 or 2) Cr(III)-macrocyclic complexes combined with vaious ligands on the axial position were primarily confirmed with the mass spectrum. Especially, when the axial ligands are malonate, oxalate, and S_(2)O_(3)^(2-), a possible thermal decomposition reaction and redox potential are considered as follows: ◁표삽입▷(본문을 참조하세요) As well, a spectrochemical series was drawn up on the basis of the ligand field strength obtained from electron absorption spertra of the complexes, [CrL_(m)(La)_(n)]^(p+) F^(-), CI^(-) ~Br^(-)<I^(-)<S_(2)O_(3)^(2-)<OH^(-)<H_(2)O<mal~NCS^(-) We can expect that there is three d-d transition d^(3) ion Tanabe-Sugano diagram. ◁표삽입▷(본문을 참조하세요) However, we found only two trasitions because the other transition {^(4)A_(2)_g(F)→^(4)T_lg(P) : v_(3)} is obscured by absorption arising from charge transfer transition. ◁표삽입▷(본문을 참조하세요)

허혈성 심질환에서 염증지표에 관한 연구

번정득,권영주,박상호,한대희,이상철,강진환,김명구,심규혁,최병조,온영근,현민수,김성구 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background : Atherosclerosis is the chief underlying cause of ischemic heart disease and there is increasing evidence that inflammation is an important determinant of the development of atherosclerosis. We assessed the levels of inflammatory markers in patients with ischemic heart disease and normal group who has normal coronary angiograms. Materials and Methods : Coronary angiography was performed in 142 patients. 107 patients of ischemic heart disease(stable angina pectoris 58, unstable angina pectoris 30, Acute myocardial infarction 19) and 38 normal control subjects. We assessed the level of inflammatory markers, such as CRP, ESR, fibrinogen and leukocyte. Results : CRP, ESR and fibrinogen values of the patients with stable angina pectoris and unstable angina pectoris were higher than that of normal control group, but there were no statistical significance. Leukocyte value of the patients with unstable angina pectoris(9003.3±701.5/mm^(3)) was significantly higher than that of the patients with stable angina pectoris(6685.5±245.8/mm^(3)) and normal control subjects(6394.3±235.1/mm^(3)). CRP, ESR and fibrinogen values of the patients with acute myocardial infarction were also higher than that of normal control subjects. CRP was 3.88±2.05 mg/dL in acute mocardial infarction group, and 0.29±0.15 mg/dL in normal control subject group(p<0.05). Fibrinogen was 541.6±45.1 mg/dL in acute myocardial infarction group, 321.4±25.6 mg/dL in normal control subject group(p<0.05). Leukocyte was 10942.1±737.6/mm^(3) in acute myocardial infarction group, 6394.3±235.1/mm^(3) in normal control subject group(p<0.05). Conclusions : This study demonstrate that CRP, fibrinogen and leukocyte values of acute myocardial infarction group were significantly higher than that of control group and stable, unstable argina pectoris group. Leucokyte values were significantly elevated in unstable angina group, but CRP values were not in unstable angina group.

V79 배양 세포에 있어 인삼추출물이 DNA복제 및 회복 합성에 미치는 분자생물학적 연구

卞富亨,徐富一,卞晟僖 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

본 연구는 인삼추출물이 DNA 복제 및 회복 합성에 미치는 영향을 조사하기 위해 수행되었다. DNA 복제 및 회복 합성도의 측정은 V79 chinese hamster lung cell의 핵 내 DNA에 [3H]-tymidine이 유입되는 양으로 측정하였다. 그 결과 인삼추출물의 농도(0~1ug/㎖)가 높을수록 점점 더 크게 감소하였다. 이와 같이 인삼추출물에 의하여 DNA 복제 합성도가 감소하는 현상은 농도가 더 높을수록 효과적인 것으로 보아 농도에 의존한다는 것을 알 수 있었다. 한편 DNA 회복 합성도에 인삼추출물이 미치는 영향을 알아보기 위해 우선 DNA를 손상시켰다. DNA를 손상시키는 물질은 여러 가지 있으나, 본 실험에서는 자외선과 methylmethane sulfonate(MMS)를 사용하였다. 이렇게 손상된 DNA가 인삼추출물(0~1ug/㎖)에 의하여 얼마나 회복되었는가를 알아보기 위하여 인삼추출물의 농도를 각각 달리하여 V79 cell에 첨가하였다. 그 결과 인삼추출물의 농도가 높을수록 DNA 회복합성도는 증가하였다. 이와 같이 인삼추출물이 DNA 복제 합성은 억제하고, DNA 회복 합성은 증가시키는 상반된 효과를 보여 주었다. 이러한 상반된 효과는 복제합성과 회복합성의 두 과정에서 서로 다른 효소체계가 관여하기 때문인 것으로 보인다. 인삼추출물이 DNA복제 및 회복합성에 미치는 영향에 대하여 보다 더 구체적인 분자생물학적 메커니즘 연구가 이루어져야 할 것이다.

초음파 가습기 디자인에 대한 연구

변상태,유희영 홍익대학교 산업디자인 연구소 2002 미술디자인 논문집 Vol.- No.7

전동칫솔 디자인에 대한 연구

변상태,유희영 홍익대학교 산업디자인 연구소 2003 미술디자인 논문집 Vol.- No.8

Representation of bounded Linear Operators on Reproducing Kernel Hilbert Space

변두원,이성희,박달원,노영순,김승동 공주대학교 과학교육연구소 2001 과학교육연구 Vol.32 No.1

재생핵 힐버트공간에서 유계인 작용소는 어떤 적분변환의 형태로 표시된다. 또한 재생핵을 이용하여 어떤 적분변환의 형태가 유계인 작용소이기 위한 필요충분조건을 구한다. The bounded linear operators on a reproducing kernel Hilbert space can be represented in the form of generalized integral transform. Also, they are completely characterized by integral kernels.

Phenytoin으로 인한 치은비대증의 치험례

변상길,이희경,진병로,오명철 영남대학교 의과대학 1986 Yeungnam University Journal of Medicine Vol.3 No.1

저자 등은 8년간 dilantin의 복용으로 상하악간에 전반적인 치은비대증을 나타낸 환자를 치은절제술과 치은성형술을 시행하고 계속적인 치석제거와 치은연하소파술을 시행하여 재발됨이 없이 심미적으로나 기능적으로 만족한 결과를 얻었기에 이에 보고하는 바이다. Enlargement of the gingiva caused by phenitoin an anticonvulsant used in the treatment of epilepsy, occurs in some of the patients receiving the drug. Its incidence varies from 3 to 62 percent, with the greater frequencies in younger patients. The hyperplasia is usually generalized throughout the mouth, but is more severe tendency in the maxillary and mandibular anterior regions. 18 year old male patient was admitted to our Department of Dentistry with the complaint of generalized painless gingival swelling. After the consult of the N.M. and laboratory study, the gingivectomy and gingivoplasty was performed. The periodontal pack and tin foil was applied on the attached gingiva to protect a surgical site and bleeding control. We obtained a good result of improved esthetics and function.

이방향성 형상기억합금을 이용한 공동 주택용 방화 댐퍼 설계 연구

황성태,이찬희,장진수,변창수,히식수렝,이상욱 순천향대학교 산업기술연구소 2022 순천향 산업기술연구소논문집 Vol.28 No.2

The purpose of this paper is to redesign, compare, and study using bi-directional shape memory alloy spring to compensate for the shortcomings of the existing fire damper performance. Through the spring constant measurement experiment, using the difference in force between the coil spring and the shape memory alloy spring, the damper closes when the set temperature is reached, and opens again when the temperature is lowered. In addition, the internal structure was redesigned through smoke leakage experiments. As a result, semi-permanent usable dampers were modeled.

분자유전학 검사로 확진된 Hereditary Neuropathy with Liability to Pressure Palsy 환자 1 례

변재환,이원영,박성익,기창석,공선영,김종원,김선희 대한근전도전기진단의학회 2003 대한근전도 전기진단의학회지 Vol.5 No.1

철근콘크리트 휨部材의 回轉能力에 對한 實驗的 基礎 硏究

邊根周,임창희,한상훈 연세대학교 산업기술연구소 1980 논문집 Vol.12 No.1

Plastic analysis of concrete indeterminate structures is based on rotation capacity of the plastic hinges. Improved rotation capacity of the hinges permits better distribution of moments and higher reserve strength of structural systems. Consequently, maximum ductility resulting in maximum rotation capability of the plastic hinges is necessary. This study is no analyse experimentically the total rotation capacity (elastic rotation+plastic rotation) of reinforced concrete simple beams subject to a transverse load at midspan. The test results examined herein indicate that the plastic-hinge rotations of simple rectangular beams,computed on the basis of a formula derived,compared well with experimentally observed hinge rotations. Therefore, the total rotation capacity in the plastic hinge stage of reinforced concrete beams without stirrup can be predicted from the formular developed. Even if research properties were properly ordered and the appropriate model chosen, extensive long-term experimentation would be necessary for any substantial improvement in our knowledge.