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( San Hui Lee ),( Eui Hyeok Kim ),( Sang Won Han ),( Sang Wun Kim ),( Young Tae Kim ) 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-
목적: The purpose of this study was to evaluate the effect of scheduled ramosetron injection during hospitalized period in patients undergoing single port access total laparoscopic hysterectomy (SPA-TLH). 방법: In this prospective, randomized, double-blinded, placebo-controlled study, 131 patients who were undergoing SPA ?TLH in National Health Insurance Service Ilsan Hospital from March 2013 to May 2014 were enrolled. Patients were divided into two groups: the ramosetron group (0.3 mg i.v.; n=65), and the placebo group (normal saline i.v.; n= 66). Both groups received their respective injection on post-operative day 1 and day 2. The incidence of postoperative nausea and vomiting (PONV), the severity of PONV (numerical rating scale 0-10), and the use of rescue antiemetic requirements during the first 24 h after surgery were evaluated. 결과: Demographic and perioperative differences were not observed between the two groups. The incidence of postoperative nausea and vomiting in the ramosetron group and the placebo group were 40.1% and 42.7%, respectively (p=0.213). However, there was a significant difference between the groups in the scale of PONV during 24 hours and 48 hours after surgery (p=0.042, p=0.034, respectively). The use of rescue antiemetics was significantly lower in the roamsetron group (p=0.021). 결론: After general anesthesia in the same fashion, the scheduled injection of ramosetron reduced the intensity of PONV and the use of rescue antiemetics. Administration of ramosetron can be considered not only immediately after the SPA-TLH but also during the recovery period.
마음읽기 중재가 자폐범주성장애 아동의 이야기 회상 산출에 미치는 효과
이산희(San-Hui Lee),서경희(Kyung-Hee Sehr),정한진(Han-Jin Jeong),유진(Jin Yu),이효진(Hyo-Jin Lee) 한국의료정보교육협회 2018 보건의료생명과학논문지 Vol.6 No.2
본 논문에서는 마음읽기 중재가 ASD 아동의 이야기 회상산출 능력에 미치는 효과를 알아보고자 하였다. 연구는 행동간 중다 기초선 설계로 이루어졌으며 기초선 1회기, 중재 8회기, 중재철회 1회기로 진행되었다. 연구 결과, 마음읽기 중재를 사용하였을 때 대상아동의 이야기 회상산출 능력이 증가되었다. 이를 통해 마음읽기 중재가 ASD 아동의 이야기 회상산출에 긍정적인 효과가 있음을 확인할 수 있었다. The purpose of this study was to investigate the effect of mind reading intervention on the recall of ASD children. This study was designed as a single case study (A-B-A). As a result of the study, when the mind reading intervention was used, the ability of the target child to recall the story was increased. This suggests that the mind reading intervention has a positive effect on the story recall of ASD children.
Trends in Robotic Surgery in Korean Gynecology
( Seungmee Lee ),( Mee-ran Kim ),( Seok Ju Seong ),( Jiheum Paek ),( Yoon S Lee ),( Eun Ji Nam ),( Yong-man Kim ),( Young-han Park ),( Tae Joong Kim ),( Yong Beom Kim ),( Tae Jin Kim ),( San-hui Lee ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
Objective: The objective of this study is to discover the trends of robotic surgery in gynecology since the introduction of robotic surgery platforms in Korea. Methods: : Data for the use of robotic surgery in gynecologic diseases were collected from the 14 hospitals that perform most of the robotic gynecologic surgeries in Korea. Records of robotic surgeries from between 2006 and 2019 were selected (n = 12,405), and data including diagnoses, approach methods, and names of surgical procedures were obtained. Statistical analysis was performed, including a trend test. Results: Overall, robotic surgery in gynecology showed an increasing trend (p < 0.001). The common cases in which robotic surgery was used for benign diseases were uterine leiomyoma, adnexal tumors, and adenomyosis, which accounted for 68%, 17%, and 9% of benign cases, respectively. Common malignant diseases were cervical cancer, endometrial cancer, and ovarian cancer, accounting for 55%, 35%, and 5% of malignant cases, respectively. This increasing trend was significantly evident in uterine leiomyoma, both single-site and multiport approaches. Conclusion: Since robotic surgical platforms were introduced in Korea, the number of gynecologic robotic surgeries has grown rapidly. Considering these data, the use of robotic surgery is expected to grow continuously for both benign and malignant gynecological diseases. A large amount of minimal invasive surgeries are expected to be replaced with robotic surgeries.
Po-Wei Lee,Tzu-Yun Wang,Yun-Hsuan Chang,Sheng-Yu Lee,Shiou-Lan Chen,Ze-Cheng Wang,Po See Chen,Chun-Hsien Chu,San-Yuan Huang,Nian-Sheng Tzeng,I Hui Lee,Kao Chin Chen,Yen Kuang Yang,Jau-Shyong Hong,Ru-B 대한정신약물학회 2020 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.18 No.1
Objective: Patients with opioid use disorder (OUD) have impaired attention, inhibition control, and memory function. The aldehyde dehydrogenase 2 (ALDH2 ) gene has been associated with OUD and ALDH2 gene polymorphisms may affect aldehyde metabolism and cognitive function in other substance use disorder. Therefore, we aimed to investigate whether ALDH2 genotypes have significant effects on neuropsychological functions in OUD patients undergoing methadone maintenance therapy (MMT). Methods: OUD patients undergoing MMT were investigated and followed-up for 12 weeks. ALDH2 gene polymorphisms were genotyped. Connors’ Continuous Performance Test (CPT) and the Wechsler Memory Scale-Revised (WMS-R) were administered at baseline and after 12 weeks of MMT. Multivariate linear regressions and generalized estimating equations (GEEs) were used to examine the correlation between the ALDH2 genotypes and performance on the CPTs and WMS-R. Results: We enrolled 86 patients at baseline; 61 patients completed the end-of-study assessments. The GEE analysis showed that, after the 12 weeks of MMT, OUD patients with the ALDH2 *1/*2+*2/*2 (ALDH2 inactive) genotypes had significantly higher commission error T-scores (p = 0.03), significantly lower hit reaction time T-scores (p = 0.04), and significantly lower WMS-R visual memory index scores (p = 0.03) than did patients with the ALDH2 1 */*1 (ALDH2 active) genotype. Conclusion: OUD patients with the ALDH2 inactive genotypes performed worse in cognitive domains of attention, impulse control, and memory than did those with the ALDH2 active genotype. We conclude that the ALDH2 gene is important in OUD and is associated with neuropsychological performance after MMT.