치과 기공사들에게서 나타나는 호흡기 증상과 이의 관련 요인

김웅철,오세윤,김지환,김진완,이준석,이가영,이세훈,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 2001 保健科學論集 Vol.27 No.1

This study was carried out to investigate subjective respiratory symptoms and their attributable factors in Korean dental laboratory technicians. A questionnaire was mailed to randomly selected 1,900 dental laboratory technicians. Among them, 1,344 dental technicians completed the questionnaires and returmned them. Validity and reliability tests on the questionnaires were carried out before the main survey. To investigate risk factors on respiratory subjective symptoms, we performed analysis on distribution of characteristics, and then investigated univariate analysis and multiple logistic regression analysis. The prevalence rate of wheezing, cough and phlegm, and dyspnea was 4.8%, 33.9%, 54.9%, respectively. Statistically significant factors inducing subjective respiratory symptoms by multiple logistic regression analysis were sex, smoking, exercise, health examination, work hours a day, investment gas, investment dust, metal fume, resin vapor, and asbestos dust. Considering the results above, it seems that most subjective respiratory symptoms are related with health habits and occupational environmental-related factors. The result, consideration in mind, suggest that health promotion programs for smoking cessation, regular health examination, and physical exercise in health habit, and improvement on casting and resin work in dental technological environment be necessary.

악안면 골격 형태에 따른 교합평면각의 변화에 관한 두부 방사선학적 연구

오세윤,김웅철,김지환,이준석,김진완,유진호,김태석 高麗大學校 倂設 保健大學 保健科學硏究所 1999 保健科學論集 Vol.25 No.1

A correlation analysis was made to understand the interaction between the growth patterns of some craniofacial skeletal components and occlusal plane inclination. 5 angular measurements(S.a. Ar.a, Go.a, UGo.a, LGo.a), 6 linear measurements(ACBL, PCBL, RH. MBL. AFH. PFH) and OP/SN. obtained from 83 cephalometric tracing records, were selected and the relationship between the occlusal plane angle and those measurements were analyzed statistically. Ramus Height(r=-0.55), Posterior Facial Height(r=-0.41), were found to be negatively related with Occlusal Plane angle, while Lower Gonial angle(r= 0.35), Saddle angle(r= 0.24) were found to be positively related with Occlusal Plane angle(p(0.05). The results obtained from the above analysis were further assessed with stepwise regression analysis, using Occlusal Plane angle as a dependant variable, and RH, LGo.a and S.a as explanatory variables. Stepwise regression analysis revealed that all the explanatory variables were found to be significant.(p<0.05) [OP/SN] = -8.74-0.33(RH)+0.23(S.a)+0.20(LGo.a). (R²=0.44). This stepwise regression analysis explains, to some extent, the relationship between the growth patterns of some craniofacial skeletal components and the occlusal plane inclination. 1. The inclination of Occlusal Plane angle is noticeably related with the growth patterns of some craniofacial skeletal components, i.e. RH, PFH, Saddle angle and Lower Gonial angle 2. In high Occlusal Plane angle, the Ram us Height tends to be shorter, and the Saddle angle and Lower Gonial angle tend to be obtuse.

요로감염증 환자의 치료에서 메로페넴(Meropenem)과 이미페넴/실라스타틴(Imipenem/Cilastatin)의 임상효과 및 안정성

김세웅,이승주,이지열,조용현,신완식,윤문수 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.1

목적 :메로페넴은 실라스타틴을 복합투여하지 않아도 되는 새로운 계열의 카바페넴계 항생물질이다. 요로감염 치료에 있어서의 메로페넴의 효과와 안전성을 평가하기 위하여 기존의 카바페넴계 항생물질인 이미페넴/실라스타틴과 동시에 비교임상실험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법을 통하여 시행하였다. 1996년 10월부터 1998년 2월까지 가톨릭대학교 의과대학 부속 성모병원 및 울산대학교 외과대학 부속 중앙병원 비뇨기과에 입원한 신우신염과 복잡성방광염 환자 115명을 대상으로 하였고, 연속적 무작위 배정방법을 통하여 메로페spa군 58명과 이미페넴/실라스타틴군 57명으로 분류하였다. 두가지 약제는 모두 0.5 g을 12시간 간격으로 정맥주사 하였고, 평균 투약기간은 4일 (3-8일) 이었다. 임상효과, 세균학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 67명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 메로페넴군은 34명이었고, 이미페넴/실라스타틴군은 33명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 메로페넴투여군은 34례중 32례 (94.1%)에서, 이미페넴/실라스타틴투여군은 33례중 29례 (87.9%)에서 유효율을 보였다. 세균학적 평가에서 메로페넴 투여군은 34례중 32례 (94.1%)에서, 이미페spa/실라스타틴투여군은 33례중 29례 (87.9%)에서 세균학적 소실율을 보였다. 세균학적 재발 은 각각 4명과 7명이 나타났고, 재감염은 메로페넴군은 나타나지 않았지만, 이미페넴/실라스타틴군은 2명이 나타났다. 임상효과와 세균학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 부작용은 메로페spa투여군 56례중 1례 (1.8%)에서, 이미페넴/실라스타틴투여군 53례중 1례 (1.9%)에서 나타났으며, 임상검사치 이상은 메로페넴투여군 45례중 10례 (22.2%)에서, 이미페넴 실라스타틴투여군 44례중 8례 (18.2%)에서 나타났으나 전체적으로 특별히 문제가 된 증례는 없었다. 결론 :결론적으로 메로페spa은 신우신염 및 복잡성방광염과 같은 요로감염에 대하여 이미페넴/실라스타틴과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Metopenem is the first of a new class carbapenems which may be administered without cilastatin. The clinical study was carried out to assess efficacy and safety of metopenem in the treatment of urinary tract infections, in comparison to imipenem/cilastatin. Methods : This was a controlled, two-center, prospective, randomized study with two parallel groups. From October 1996 until February 1998, a total of 115 consecutive patients with urinary tract infections, such as pyeolonephritis and complicated cystitis, were randomly allocated into two groups, 58 in the meropenem group and 57 in the imipenem/cilastatin group. Both drugs were administered intravenously, at a dose of 0.5 g every 12 hours. The mean duration of therapy was 4 days (3-8 days) for both treatment. Clinical and bacteriological reponses were assessed at the begining of treatment, during treatment, at the end of treatment, and follow-up (1-2 weeks). Results : A total of 67 patients, 34 of meropenem and 33 of imipenem/cilastatin, were evaluable for response. Overall, a positive clinical response (recovery and improvement) was observed in 32 (94.1%) of 34 patients treated with meropenem and in 29 (87.9%) of 33 patients with imipenem/cilastin and the corresponding eradication rates of the primary pathogens were 32 (94.1%) of 34 patients and 29 (87.9%) of 33 patients, respectively. The microbiological relapse after the treatment completion was recorded in 4 patients treated with meropenem and 7 patients given imipenem/cilastath and superinfections occurred in none and 2 patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. Both drugs were well tolerated with adverse events considered to be related to therapy being recorded for 1 (1.8%) of 56 patients treated with meropenem and 1 (1.9%) of 53 of those who had been given imipenenjcilastatin. Conclusion : Empirial monotherapy with meropenem was therefore as effective and as well tolerated as that with imipenem/cilastatin for the treatment of urinary tract infections.

韓牛 肥育促進을 위한 Cobalt(Co) 給與效果에 關한 硏究

尹熙燮,吳世正,姜昌鎭,金時明 건국대학교 1978 學術誌 Vol.22 No.1

For an increase of body weight, feed efficiency, and profitability of Korean cattle fattening through the effective fattening of the Korean cattle concentrates with an addition of 0.05 mg of cobalt for test plot I, 0.05 mg of cobalt for test plot II 0.10 mg, and 0.15 mg for test plot III, per kg of concentrate were given to sampled cattle. Experiments were designed to repeat control plot and three test plots (I, II, III) five times far 140 days on the 20 cattle sampled by completely randomized design. The results of the experiments are presented in the following. I. Amount of Body Weight Gain The average weight gain per head, and weight gain per day are commonly highest in the test plot II (132.6 kg ㆍ 0.92 kg), second in the test plot I (128.5 kg ㆍ 0.91 kg), third in the test plot III (121.1 kg ㆍ 0.87 kg), and lowest in the control plot (120.4 kg ㆍ 0.87 kg). The rull hypothesis was accepted while there was no statistical significance between the test plots and the control plot, and also among the test plots. But the test plots with an addition of cobalt resulted in higher gain of body weigh comparing to that of the control plot. II. Amount of Feed Intake and Feed Effeciency The efficiency of concentrate required to increase on Kilogram of beef was highest in the test plot II 6.42 kg, second in the test plot I 6.53kg, third in the test plot III 7.00 kg, and lowest in the control plot 7.18 kg respectively. In case of flay and pellets the test plot I showed the highest weight gain, the test plot II, and III resulted in the same performance, and the control plot was the lowest one in the gain of body weight. There was no statistical significance between the test plots and control plot, and among the test plots. Thus, the test plots with ail addition of cobalt comparing to the control plot resulted in a higher feed efficiency. III. Profitability Feed costs required to increase one Kilogram of fresh meat was 636 casts won in the test plot II, 641 won in the test plot I, 685 fresh meat won in the test plot III, and 703 won in the control plot respectively. While there was no statistical significance with profitability, the test plot with an addition of cobalt required lower feed cost increase one kilogram if fresh meat comparing to the control plot. IV. Fattening outcome Of the sampled 20 cattle 18 cattle were slaughtered after 6 days from the last day of the tests. The carcass rate of the sloughtered cattle was 56.4 percent in the test plot II, 55.0 percent in the test I, 54.8 percent in the test plot III, and 54.6 percent in the control plot. There was no statistical significance with the rate of carcass, but the test plats with an addition to cobalt presented a little higher carcass rate comparing to the control plot. It was rather difficult to distinguish meat color with eyes, but comparing to the control plot the meat color of the test plots was heavily red.

현행 국사교육 수행평가의 실제와 문제점 및 해결방안

김현진,김세윤 신라대학교 교육과학연구소 2000 교육과학연구 Vol.- No.5

李肯翊의 燃藜室記述

金世潤 新羅大學校 1984 論文集 Vol.17 No.-

The present thesis attempts to examin some characteristics of YonRyoSilkiSul. Therefore this thesis will be helpful in understanding the history books and the concept of Silhak(實學)in the 18.9C Chosun Dynasty. It is hoped that the present thesis will contribute to a fresh understanding of this topic. Editing of YRSKS by Lee Kung Ik (李肯翊) originated from the dissatisfaction about the previous history books and related to the author's personal aspiration to become a historiographer. To describe a wider and more original history book, though Lee K. I. stated he applied the KiSaBonMal-Style(紀事本末體) in the preface, he applied it only partially. On the whole he applied KiJun-Style (紀傅體). Structure of WonJip(原集), application of KiSaBonMal--Style, addition of the titles of reference books and wide collection of materials can be seen in other history books in the same period. Hitherto most scholars have rated YRSKS hiph in its originality. Because characteristics of YRSKS are not original in several aspects, however, it must be reconsidered to involve YRSKS in the category of Silhak.

뇌졸중 및 뇌손상 환자의 경관 유동식이에섬유소 첨가시 설사에 대한 효과

전세일,김동아,온석훈,조성래,서정훈,윤태준,유성,전중선,김정남,윤지영 大韓再活醫學會 2000 Annals of Rehabilitation Medicine Vol.24 No.5

급성 단순하부요로감염증 치료에서 노르플록사신과 루플록사신의 임상효과 및 안전성

김세웅,이지열,이승주,조용현,윤문수 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.1

목적 : 루플록사신은 긴 반감기와 넓은 항균력을 가진 퀴놀론계 항생물질이다. 급성 단순하부요로감염 치료에 있어서의 루플록사신의 효과와 안전성을 평가하기 위하여 기존의 퀴놀론계 항생물질인 노르플록사신과 비교임상시험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법으로 진행하였으며 1997년 8월부터 1999년 3월까지 가톨릭대학교 의과대학 부속 성모병원 비뇨기과에 내원한 급성 단순하부요로감염 환자 72명을 대상으로 하였다. 연속적 무작위 배정방법을 통하여 루플록사신군 36명과 노르플록사신군 36명이 루플록사신 400㎎을 단회 경구투여 받거나 노르플록사신 400㎎을 12시간 간격으로 3일간 6회 경구투여 받았다. 임상효과, 미생물학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 64명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 루플록사신군은 32명이었고, 노르플록사신군은 32명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 루플록사신투여군은 32례중 32예(100%)에서, 노르플록사신투여군은 32례 중 31례(96.9%)에서 만족할 만한 결과를 얻었다. 미생물학적 평가에서 루플록사신투여군은 32례 중 29례(90.6%)에서, 노르플록사신투여군은 32례 중 28례(87.5%)에서 미생물학적 소실을 보였다. 미생물학적 재발은 루플록사신군과 노르플록사신군에서 각각 1례(3.1%)과 2례(6.3%)가 나타났고, 재감염은 각각 2례(6.3%)와 1례(3.1%)가 나타났다. 임상효과와 미생물학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 약물역동학적 검사상 루플록사신은 노르플록사신에 비해 높은 MIC를 갖고 있지만 긴 반감기를 통해 소변내에서 높은 농도와 요 살균력을 유지함을 알 수 있었다. 부작용은 루플록사신투여군 34례 중 5례(14/7%)에서, 노르플록사신투여군 35례 중 1례(2.9%)에서 나타났으며, 대부분의 소화기계통의 이상반응 이었으며, 모두 경증으로 24시간 이내에 소실되었다. 루플록사신투여군 중 2례에서는 경증의 중추신경계의 이상반응이 관찰되었다. 결론 : 결론적으로 루플록사신은 급성 단순하부요로감염에 대하여 1회 투여만으로도 노르플록사신의 3일 투여법과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Rufloxacin is a broad-spectrum quinolone that exhibits a prolonged elimination half-life. The purpose of this study is to evaluate the efficacy and safety of a single dose of rufloxacin, campared with those of a norfloxacin standard treatment. Methods : This was a open. randomized. parallel-group, phase 11 clinical trial. A total of 72 women with acute lower urinary tract infections were included and randomly assigned to one of the treatment regimens: rufloxacin 400㎎ single dose, or norfloxacin 400㎎ b.i.d. for 3 days. Clinical and bacteriological assessments were performed twice at the third day and the seventh or tenth day after inclusion. Results : A total of 64 patients(32 and 32 patients in the rufloxacin and norfloxacin groups, respectively) were considered clinically and bacteriologically evaluable. Overall, a clinical response(recovery and improvement) was observed in 32 (100%) of 32 patients treated with rufloxacin and in 31 (96.95) of 32 patients with norfloxacin. The corresponding eradication rates of the primary pathogens were 90.6%(29/32) and 87.5%(28/32), respectively. The microbiological relapses between the seventh and tenth day were recorded in 1 patient(3.1%) and 2 patients(6.3%) in the rufloxacin and norfloxacin groups, respectively. The superinfections occurred in 2(6.3%) and 1(3.1%) patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. The pharmacodynamic evaluation showed similar median urine bactericidal titers(UBT) for both treatment groups against initial isolates, despite a higher MIC of rufloxacin than that of norfloxacin. Five patients (14.7%) in the rufloxacin group and 2 patients (5.7%) in the norfloxacin group reported 9 and 4 adverse events, respectively, almost all of them being mild and lasting <24 h. Overall, gastrointestinal reactions were the most frequent adverse events reported. However, 2 patients treated with rufloxacin reported 3 central nervous system adverse events. Conclusion : This study suggests that single dose of rufloxacin treatment is effective and well tolerated as norfloxacin 3-day standard treatment in acute uncomplicated lower urinary tract infections.

간세포암과 감별이 어려웠던 악성중피종 치험 1예

김선문,허원석,채경훈,강윤세,정재훈,김연수,박기오,문희석,이엄석,김석현,성재규,이병석,이헌영,신경숙,조준식,송인상,강대영 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

Malignant peritoneal mesothelioma is a rare neoplasm that arises from the mesothelium of a serosal cavity and is a rapidly fatal disease with a median survival of 4 to 12 months for untreated cases. Recently, we experienced a case with malignant peritoneal mesothelioma who was suspected hepatocelluar carcioma by abdominal CT scan and was confirmed by biopsy including immunohistochemical stain(calretinin) after surgery. We performed tumor excisions and wedge resection of the liver(segment Ⅷ)and inserted Tencoff catheter in abdominal cavity at 25th day of post-operation. We treated with intraperitoneal paclitaxel(25mg/m^(2)/day for 5 days) six courses monthly. She was well tolerable and is still living without any evidence of recurrence for 14th month of post-operation.

경희대학교 수원 캠퍼스의 교문디자인 연구

김동찬,이윤수,박중구,황세현,김명기 경희대학교 디자인연구원 2000 예술· 디자인학연구 Vol.3 No.1

The Suwon Campus of Kyunghee University was decided to rebuild a university gate to make new image of the university for a new millenium. The purpose of this study is to design a university gate not only for a gate but also for a commemorative environmental model which presents a spirit and idea of the Kyunghee University. The entire design of the gate has a renaissance style, the design of it's center has a triumphal arch form which cars can go through, and the design of it's side has a corridor form which pedestrians can walk. The gate is designed to present the spirit for human and world peace which Kyunghee University intends.