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김새인,이동현,김광현,류동열,김승정,강덕희,최규복,이신아 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.3
Objectives: Metabolic acidosis frequently develops in patients after neobladder reconstruction. However, the incidence of metabolic acidosis in patients with neobladder and the factors associated with the development of metabolic acidosis have not been well elucidated. We aimed to investigate the incidence and the potential predictors for the development of metabolic acidosis after neobladder reconstruction with intestinal segment. Methods: We included patients who underwent neobladder reconstruction using intestinal segment at Ewha Womans University Mokdong Hospital between January 1, 2005 and December 31, 2014. A subgroup of patients according to the time of metabolic acidosis occurrence was further analyzed in order to characterize predictors for metabolic acidosis. Results: Metabolic acidosis was encountered in 79.4% of patients with neobladder during follow up period. When patients were divided into 2 groups according to anion gap (AG), total CO2 (18.9±2.1 mEq/L vs. 20.0±1.3 mEq/L, P=0.001) and chloride (106.6±4.9 mE/L vs. 109.4±3.6 mEq/L, P<0.001) were significant different between groups with AG>12 and AG≤12. Furthermore, when patients were divided into 3 groups; patients with metabolic acidosis at postoperative day (POD) 1; from POD 2 to 14 days; after 14 days, there was significant difference among those subgroups. Conclusion: Our study showed the rate of metabolic acidosis in patients underwent neobladder reconstruction and the difference between patients with metabolic acidosis and those without metabolic acidosis for the first time in Korea. In the future, well designed prospective study will be needed to prevent metabolic acidosis after neobladder reconstruction.
雜犬에서 Isoflurane 全身痲醉時 Labetalol과 Sodium Nitroprusside가 心血力學에 미치는 影響
우현제,이정은,최세진 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1
Many studies have been performing to attenuate hemodynamic responses in related to anesthesia of hypertensive patients because increased blood pressure and heart rate may be even fatal. The author performed this experimental study to evaluate the hemodynamic effect of labetalol which has dual site of action(non-specific beta and postsynaptic alpha 1 receptor blockade) and SNP on cardiovascular system under the 1 % isoflurane anesthesia in 14 mongrel dogs. Heart rate(HR), systolic arterial blood pressure(SAP); diastolic arterial blood pressure(DAP), mean arterial blood pressure(MAP), central venous pressure(CVP), pulmonary arterial pressure (PAP), pulmonary capillary wedge pressure(PCWP), and cardiac output(CO) were measured after labetalol 0.08mg/kg, 0.24mg/kg, and 0.72mg/kg intravenous bolus injection and SNP 0.7mg /kg/min, 2.1mg/kg/min, and 6.3mg/kg/min intravenous dripping. Besides stroke volume (SV), cardicac index(CI), left ventricular stroke work index(LVSWI), systemic vascular resistance (SVR) and pulmonary vascular resistance(PVR) were calculated. The results were summerized as follows 1. SAP, DAP and MAP were decreaed significantly in both groups. HR were decreased significantly in labetalol group but there was no change in SNP group. 2. PCWP showed a tendency to increase in labetalol group but to decrease in SNP group, PAP showed no change in both groups. 3. CO and CI were decreased significantly but SV was not changed in labetalol group. There were no changes in SNP group. LVSWI showed a tendency to decrease in both groups. 4. CVP, SVR and PVR were not changed in both groups. The author conclude both labetalol and SNP are effective to attenuate hemodynamic responses, in hypertensive patients. But labetalol is preferable for hypertensive patient with coronary heart. disease because it has dual blocking action.
류한영,설정현,김정철,한승세,우상현,최시호 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.2
Bronchopleural fistula and chronic empyema are the difficult problems in the thoracic surgery field. We experienced 3 cases of chronic empyema and complicated bronchopleural fistulas treated with muscle flap and concomitant thoracoplasty. The causative primary diseases were pulmonary tuberculosis and bronchiectasis. All the three cases have failed to control the chronic empyema and bronchopleural fistula with conventional method such as closed or open drainage and Eloesser flap after lobectomy. The unresponsive infection on bronchopleural fistula and pleural space was well controlled after muscle flap with thoracoplasty. Complete decortication, closure of bronchopleural fistula as much as possible and coverage of closed fistula with good vascularized tissue are the essential factors for the success of operation on chronic empyema and bronchopleural fistula. The results of operations were satisfactory and the respiratory function was well preserved or improved in one patient. But, the contour of chest wall was deformed in patient with extensive concomitant thoracoplasty.
조산 예측인자로서 Fetal Fibronectin과 자궁경부 개대 및 길이 측정의 임상적 의의
정두용,방세창,유정현,김소정 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-
Twenty seven pregnant women between 22 and 36 weeks of gestational age presenting with preterm labor, intact membrane and less than 3cm cervical dilatation visited the department of Obstetrics and Gynecology, KonKuk University Medical Center, Choongju Hospital from June 1, 1998 to March 31, 1999. These patients' cervicovaginal swabs were assessed for the presence or absence of fetal fibronectin by means of ROM-CHECK(monoclonal antibody assay) the positivity of which was revealed by a colorimetric reaction. Also cervical parameters such as cervical length, presence of funneling, funnel length and funnel width were measured by transvaginal ultrasonography. We compared the diagnostic performances of these results in the prediction of preterm delivery of patients with preterm labor and intact membranes. The results were as follows; 1. The overall incidence of preterm delivery(< 37 weeks) was 44%; 12 among 27 patients. 2. There were statistically significant differences in the mean Bishop scores(4.58±0.48 vs 2.13±0.36), the mean gestational age at first admission with preterm labor(33.33±0.38 vs 29.47±1.06 weeks), the mean gestational age at delivery(34.92±0.34 vs 38.27±0.34 weeks) and interval from first admission to delivery(284.2±103.1 vs 1,339.2±154.4 hour) and mean birthweight(2,620±100 vs 3,131±100g) between the preterm delivery group and term delivery group. 3. The positive rates of fetal fibronectin in the vaginal fluid of preterm delivery group and term delivery group were 42%(5/12) and 0%(0/15). 4. The mean cervical length, presence of cervical funneling, funnel length and funnel width were 22.25±2.61mm vs 30.67±1.63mm; 75%(9/12) vs 47%(7/15); 11.83±3.40mm vs 4.53±1.64mm; 11.50±2.92mm vs 6.07±1.87mm in preterm delivery group and term delivery group, and there were statistical significances in the mean values of cervical length and funnel length between each group. 5. The sensitivities and specificities of fetal fibronectin, cervical length(≤25mm), cervical funnel length(≥10mm) and width(≥16mm) as a predictor of preterm delivery were 42% and 100%; 75% and 80%: 50% and 87%; 33% and 93%. The positive predictive values and negative predictive values of fetal fibronectin, cervical length(≤25mm), cervical funnel length(≥10mm) and funnel width(≥16mm) as a predictor of preterm delivery were 100% and 68%; 75% and 80%; 75% and 68%; 80% and 64%. 6. The sensitivities and specificities of the combined use of fetal fibronectin, cervical length(≤25mm), cervical funnel length(≥10mm) and width(≥16mm) as a predictor of preterm delivery were 83% and 67%. The positive predictive value and negative predictive value of the combination of fetal fibronectin, cervical length(≤25mm), cervical funnel length(≥10mm) and width(≥16mm) as a whole as a predictor of preterm delivery were 67% and 83%.
A New Winter-Type Malting Barley Cultivar, "Dajin" with Powdery Mildew and BaYMV Resistance
Jong Nae Hyun,Sae Jung Suh,Hyun Tae Kim,Seong Bum Baek,Sang Ik Han,Jong Rae Kang,Jong Min Ko,Sea Gye Lim,Jong Chul Park,Mi Jung Kim,Jung Gon Kim,Jung Hyun Nam,Duck Yong SuhDa 한국육종학회 2006 한국육종학회지 Vol.38 No.1
Suwon295 at the Honam Agricultural Research Institute (HARI) in 2005. An elite line, 953017-BG-BN-BN-53N, was selected in2000 and designated as Milyang126. It showed good agronomic performance in the regional adaptation yield trials (RYT) from2003 to 2005
A New Malting Barley Cultivar Resistant to BaYMV, "Sinho"
Sae Jung Suh,Seong Bum Baek,Jung Gon Kim,Duk Hwan Jang,Mi Young Hong,Su Kyung Kim,Ya Seong Lee,Dae Ho Kim,Chang Yong Yun,Moon Woong Park,Yong Woong Ha,Jung Hyun Nam,Dong Ju Kang 한국육종학회 2003 한국육종학회지 Vol.35 No.2
A new malting barley cultivar, “Sinho”, with a resistant gene (rym5) to barley yellow mosaic virus (BaYMV) was developed by the barley breeding team of National Crop Experiment Station (NCES), RDA in 1999. This cultivar was derived from the cross between
A New Covered Barley Cultivar Resistant to Powdery Mildew and BaYMV, "Sanglog"
Jung Gon Kim,Seong Bum Baek,Sae Jung Suh,Moon Seok Kang,Jong Ho Lee,Jung Hyun Nam,Gun Yong Park,Moon Woong Park,Yong Woong Ha,Moo Nam Chung 한국육종학회 2003 한국육종학회지 Vol.35 No.2
Sanglog', a new covered barley cultivar resistant to powdery mildew and barley yellow m osaic virus (BaYMV) was developed by the barley breeding team of the National Crop Experim ent Station (NCES), RDA in 1999. This variety was derived from a cross betwe
( Sae Jung Na ),( Jae Myung Park ),( Joo Hyun O ),( Han Hee Lee ),( Kyo Young Song ),( Sung Hak Lee ),( Sang Young Roh ),( Myung Gyu Choi ),( Cho Hyun Park ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: This study assessed the prognostic value of metabolic parameters from preoperative 18F-FDG PET/CT in patients with curative surgical resection of stage III gastric cancer. Methods: Patients who underwent staging preoperative 18F-FDG PET/CT and con- fi rmed to have stage III gastric cancer after curative surgical resection were retrospectively enrolled. The maximum standardized uptake value (SUVmax) and peak SUV (SUVpeak) of the primary gastric cancer were measured from all patients. In addition, the metabolic tumor volume (MTV) and total lesion glycolysis (TLG) were computed in all cases showing perceptible FDG uptake. The prognostic values of the PET parameters and clinicopathologic factors for recurrence free survival (RFS) and overall survival (OS) were evaluated. Results: 138 patients (male 89, female 49) were included, with age ranging from 26 to 83 years (mean±SD, 60.5±8.5). The TNM stage was IIIa in 41 patients, IIIb in 47 patients and IIIc in 50 patients. Mean follow up duration was 41±18 month (range 0~65, median 46 months). On univariate analysis, the pathologic T stage (pT), pathologic N stage (pN), TNM stage, vein invasion, SUVmax and SUVpeak were signifi cant prognostic factors for RFS (pmax, SUVpeak, and TLG were signifi cant factors for OS (pmax were prognostic for RFS, while TNM stage and age were the prognostic factors for OS. Conclusions: Higher SUVmax and SUVpeak of the primary tumor were associated with signifi cantly shorter RFS and OS. 18F-FDG PET/CT in patients with stage III gastric cancer provides prognostic information prior to surgery.
A New Two-rowed, Naked and Waxy Barley Cultivar, "Pungsanchal" Suitable for Split Polished Grains
Jung Gon Kim,Seon Bum Baek,Moon Seok Kang,Sae Jung Suh,Gun Yong Park,Moon Woong Park,Jung Hyun Nam,Jong Ho Lee,Young Koo Son,Choon Woo Lee,Hong Sik Kim,Chang Yong Yun,Ya Seong Lee 한국육종학회 2003 한국육종학회지 Vol.35 No.2
A new two-rowed naked waxy barley cultivar, 'Pungsanchal', was developed for split polished grains by the National Crop Experiment Station(NCES), RDA in 2001. This cultivar was derived f rom a cross between 'SB901258GG-B' and 'Suwon212' in 1991. The f ina